#NEXUS 
[MacClade 4.08 registered to Tomoaki Nishiyama, National Institute for Basic Biology]


BEGIN DATA;
	DIMENSIONS  NTAX=91 NCHAR=1140;
	FORMAT DATATYPE=PROTEIN  SYMBOLS = " 1 2 3 4"  MISSING=? GAP=- ;
MATRIX
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'gi|15242626|ref|NP 201116.1| HDA6 (HISTONE DEACETYLASE 6); histone deacetylase [Arabidopsis thaliana] >gi|23296897|gb|AAN13198.'    -----------------------------------------------------------------------------------------------------------------------MEADESGISLP----SGPDGRKRRVSY----------------FYE-PTIGDYYYGQGHPMKPHRIRMAHSLIIHYHLH--RRLEIS-------------------------RPSLADASDIGRFHSPEYVDFLASVSPESMGD--PSAARNLRRFNVGE--DC--PVFDGLFDFCRASAGGSIGAAVKLNRQDADIAINWGGGLHHAKKSEASGFCYVNDIVLGILELLKMFK-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKFGDF-FPGTGHIRDVGAEKGKYYALNVPLNDGMDDESFRSLFRP-LIQKVM----------EVYQPEA--------VVLQCG-----ADSLSGDRLGCF--NLSVKGHADCLRFLRSYNVPLMV-LGGGGYTIRNVARCWCYETAVAVG--VEPDNKLPYNEYFEYFGPDYT-LHVDP-SPMENLNTPKDMERIRNTLLEQLSGLIHAPSVQFQHTPPV--N---RVL----------------------DEP-EDDMETR-PKPRIWSGTATYE-----SDSDDD-DKPLHGYSCRGG-----------ATTDRD-----------------STGEDEMDD-DNPEPDVNPPSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [471]
'gi|11066141|gb|AAG28475.1| putative histone deacetylase [Arabidopsis thaliana]'                                    -----------------------------------------------------------------------------------------------------------------------MEADESGISLP----SGPDGRKRRVSY----------------FYE-PTIGDYYYGQGHPMKPHRIRMAHSLIIHYHLH--RRLEIS-------------------------RPSLADASDIGRFHSPEYVDFLASVSPESMGD--PSAARNLRRFNVGE--DC--PVFDGLFDFCRASAGGSIGAAVKLNRQDADIAINWGGGLHHAKKSEASGFCYVNDIVLGILELLKMFK-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKFGDF-FPGTGHIRDVGAEKGKYYALNVPLNDGMDDESFRSLFRP-LIQKVM----------EVYQPEA--------VVLQCG-----ADSLSGDRLGCF--NLSVKGHADCLRFLRSYNVPLMV-LGGEGYTIRNVARCWCYETAVAVG--VEPDNKLPYNEYFEYFGPDYT-LHVDP-SPMENLNTPKDMERIRNTLLEQLSGLIHAPSVQFQHTPPV--N---RVL----------------------DEP-EDDMETR-PKPR?WSGTATYE-----SDSDDD-DKPLHGYSCRGG-----------ATTDRD-----------------STGEDEMDD-DNPEPDVNPPSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [471]
'gi|4193320|gb|AAD10139.1| histone deacetylase [Zea mays]'                                    -----------------------------------------------------------------------------------------------------------------------MAASGEGVSLP-SPAGGEDAHRRRVSY----------------FYE-PSIGDYYYGQGHPMKPHRIRMAHSLVVHYGLH--RLLELS-------------------------RPYPASEADIRRFHSDDYVAFLASATGNPGVL----DPRAIKRFNVGE--DC--PVFDGLFPFCQASAGGSIGAAVKLNRGDADITVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKFHR-------------------------------------------RVLYVDIDVHH--GDGVEEAFFTTNRVMTVSFHKYGDF-FPGTGHITDVGAAEGKHYALNVPLSDGIDDTTFRGLFQC-IIKKVM----------EVYQPDV--------VVLQCG-----ADSLAGDRLGCF--NLSVKGHADCLRFLRSYNVPMMV-LGGGGYTIRNVARCWCYETAVAVG--VEPDNKLPYNDYYEYFGPDYT-LHIQP-KSVENLNTTKDLENIKNMILENLSKIEHVPSTQFHDRPSD--P---EAP----------------------EEK-EEDMDKR-PPQRS--RLWSGGAY--DSDTEDP--------DSLKS-----------EGKDV--------------------TANFQMK-DEPKDDL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [458]
'gi|52548252|gb|AAU82113.1| histone deacetylase [Triticum aestivum]'                                    -----------------------------------------------------------------------------------------------------------------------MAASGEGASLP-SPAGGEDSRRRRVSY----------------FYE-PTIGDYYYGQGHPMKPHRIRMAHSLVIHYGLH--RLLELS-------------------------RPFPASEADISRFHSDEYVSFLASATGNPTIL----DPRAVKRFNVGE--DC--PVFDGLFPFCQASAGGSIGAAVKLNRGDADITVNWAGGLHHAKKGEASGFCYVNDIVLAILELLKFHR-------------------------------------------RVLYVDIDVHH--GDGVEEAFFTTNRVMTVSFHKYGDF-FPGTGHITDVGAGEGKHYAVNVPLSDGIDDDTFRDLFQC-IIKRVM----------EVYQPEV--------VVLQCG-----ADSLAGNRLGCF--NLSVKGHADCLRFLRSFNIPMMV-LGGGGYTIRNVARCWCYETAVAVG--VEPDNKLPYNDYYEYFGPDYN-LHIQP-RIVENLNTTKDLENIKNMILDHLSKLEHVPNAQFHERPSD--P---EGP----------------------EEK-EEDMDKR-PAQRS--RLWSGGAY--DSDTEDP--------DNMKT-----------EANDL--------------------SANSIMK-DASNDDL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [458]
'gi|50944529|ref|XP 481792.1| putative histone deacetylase [Oryza sativa (japonica cultivar-group)] >gi|38637022|dbj|BAD03280.1|'    -----------------------------------------------------------------------------------------------------------------------MAASGEGASLA-SAAGGEDGRRRRVSY----------------FYE-PSIGDYYYGQGHPMKPHRIRMAHSLVVHYGLH--RLLELS-------------------------RPYPASDADIRRFHSDDYVAFLASATGNPALL----DARAVKRFNVGE--DC--PVFDGLFPFCQASAGGSIGAAVKLNRGDADITVNWAGGLHHAKKGEASGFCYVNDIVLAILELLKFHR-------------------------------------------RVLYVDIDVHH--GDGVEEAFFTTNRVMTCSFHKYGDF-FPGTGHITDVGAGEGKHYALNVPLSDGIDDDTFRDLFQC-IIKKVM----------EVYQPDV--------VVLQCG-----ADSLAGDRLGCF--NLSVKGHADCLRYLRSFNIPMMV-LGGGGYTIRNVARCWCYETAVAVG--VEPDNKLPYNDYYEYFGPDYN-LHIQP-RSVENLNSTKDLENIKSMILDHLSKIEHVPSTQFHDRPSD--P---EAP----------------------EQE-EEDMDKR-PPQRS--RLWSGGAY--ESDTEDP--------DNMKT-----------ETNDL--------------------SASSVMK-DESNDDS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [458]
'gi|17017398|gb|AAL33653.1| histone deacetylase [Zea mays]'                                    ----------------------------------------------------------------------------------------------------------------------------------------------RVSY----------------FYE-PSIGDYYYGQGHPMKPHRIRMAHSLVVHYGLH--RLLELS-------------------------RPYPASEADIRRFHSDDYVAFLASATGNPGVL----DPRAIKRFNVGE--DC--PVFDGLFPFCQASAGGSIGAAVKLNRGDADITVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKFHR-------------------------------------------RVLYVDIDVHH--GDGVEEAFFTTNRVMTVSFHKYGDF-FPGTGHITDVGAAEGKHYALNVPLSDGIDDTTFRGLFQC-IIKKVM----------EVYQPDV--------VVLQCG-----ADSLAGDRLGCF--NLSVKGHADCLRFLRSYNVPMMV-LGGGGYTIRNVARCWCYETAVAVG--VEPDNKLPYNDYYEYFGPDYT-LHIQP-KSVENLNTTKDLENIKNMILENLSKIEHVPSTQFHDRPSD--P---EAP----------------------EEK-EEDMDKR-PPQRS--RLWSGGAY--DSDTEDP--------DSLKS-----------EGKDV--------------------TANFQMK-DEPKDDL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [436]
lcl|Smo_HDA6_40_1_unnamed_protein_product                                    -------------------------------------------------------------------------------------------------------------------------MDGSGNSLA----SGPEGRSKRVAY----------------FYD-PEVGNYYYGQGHPMKPHRIRMTHSLLVHYGIH--NKLEVL-------------------------KPLPAKDRDLCRFHADDYVAFLRVITPETQHE----HLRALKRFNVGE--DC--PVFDGLYSFCQTYAGGSVGGAVKLNHGHSDIAVNWSGGLHHAKKCEASGFCYVNDIVLAILELLKYHA-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKFGDY-FPGTGDVRDMGHAKGKYYSLNVPLNDGIDDESYHSLFKP-IITKVM----------EVFQPGA--------VVLQCG-----ADSLSGDRLGCF--NLSIKGHAQCVKFMRSFNVPLLL-LGGGGYTIRNVARCWCYETAVAVG--VELEDKMPYNEYYEYFGPDYT-LHVTP-SNMENQNSAQYLESIRNRLLENLSNLQHVPSVPFQERPPD--T---DLPEEVSL---------------------SVASTWR-QSPSARDDRIKKEKEELMDEGSDIDGDLPKVQQEPQD----------------------------------DQPTAMETD-AKAEEK---------------------------------------------------------------------------CSSLLPDAPSAPLASSADTAHEPNEQSTSNTNWQLVTTSTAATAAAMNARSPL-----APPAPNQAPPSSTAIATAAWTPPTSATVV------------ARLPRFSASSGAPVAATVTATATVTAVTSSTVANSPAPAPVPAALARVTEAPTPMTP----------------------------------------------------------------------------------------------------------------------------------   [602]
lcl|Ppa_HDA6_9_1_unnamed_protein_product                                    --------------------------------------------------------------------------------------------------------------------------MEGGNSLV---AG-PEGRKRRVSY----------------FYD-PDVGNYYYGQGHPMKPHRIRMAHSLLVHYNLH--TRMEVL-------------------------RPYPARDRDLCRFHADDYVSFLKEVTPETQHD----QMRQLKRFNVGE--DC--PVFDGLYNFCQTYAGGSVGGAVKLNHGHSDIAINWAGGLHHAKKCEASGFCYVNDIVLAILELLKYHQPLNLLKLRHSVRVSNVAFIIVQAVLEEVQLDRKCFTDIPVVVVRVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKFGDY-FPGTGDVRDIGHGKGKYYSLNVPLDDGIDDESYQSLFKP-IMSKVM----------EVFQPGA--------VVLQCG-----ADSLSGDRLGCF--NLSVKGHAECVRFMRSFNVPLLL-VGGGGYTIRNVARCWCYETAVAVG--EELDDRLPHHEYYEYFGPDYS-LHVAP-SNMANQNSKKDIDNLRMKLLENLSKLQHVPSVPFSERPPD--T---ELPENVFVAFKLNLSFECAFWIMQEDED-LELRDKG----------RTWDGE--LSDSDSE------DHDLRRR------------NQGVFASETAFPR---------RPPPLGSTR-GKSEEE---------------------------------------------------------------------------IGEAMSSDDEIDM---EDEARKGPEDTKDAAEEHVEMDVDPAVEAGPEDETPSNIEMGGAPQAEQADTSAGAAPAVAVAPPTTTTNV------------DR------ESSVSTAAPFLLHPSPSSTTAAVKPAASSSGRVTERSTVAPAATNFNQSNSFGGAPSFTQRSYVPPQPSAGSNMPWRQSQPGNHAKTSNQSNNSHSLPQAGVPLGIRAGPPSQAGGGASVPGSGSGILSRSSGNPVLPPGRPGAPGPGSYSARPAGPTNRFASTINPGANLGEPAQTDS   [786]
'gi|11066139|gb|AAG28474.1| putative histone deacetylase [Arabidopsis thaliana] >gi|2318131|gb|AAB66486.1| histone deacetylase ['    --------------------------------------------------------------------------------------------------------------------MD-----TGGNSLA---SG-PDGVKRKVCY----------------FYD-PEVGNYYYGQGHPMKPHRIRMTHALLAHYGLL--QHMQVL-------------------------KPFPARERDLCRFHADDYVSFLRSITPETQQD----QIRQLKRFNVGE--DC--PVFDGLYSFCQTYAGGSVGGSVKLNHGLCDIAINWAGGLHHAKKCEASGFCYVNDIVLAILELLKQHE-------------------------------------------RVLYVDIDIHH--GDGVEEAFYATDRVMTVSFHKFGDY-FPGTGHIQDIGYGSGKYYSLNVPLDDGIDDESYHLLFKP-IMGKVM----------EIFRPGA--------VVLQCG-----ADSLSGDRLGCF--NLSIKGHAECVKFMRSFNVPLLL-LGGGGYTIRNVARCWCYETGVALG--VEVEDKMPEHEYYEYFGPDYT-LHVAP-SNMENKNSRQMLEEIRNDLLHNLSKLQHAPSVPFQERPPD--T---ETPEV--------------------DED-QEDGDKR-WDPDS-------DMD--VDD---------------DR-----------KPIPS--------R---------VKREAVEPD-TKDKDG---------------------------------------------------------------------------LKGIMERGKGC----------EVEVDESG--------STKVTGVNPVGV---------EEASVKMEEEGTNKGGAEQAFPP------------------KT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [501]
'gi|15233694|ref|NP 195526.1| HD1; histone deacetylase [Arabidopsis thaliana] >gi|31711912|gb|AAP68312.1| At4g38130 [Arabidopsis'    --------------------------------------------------------------------------------------------------------------------MD-----TGGNSLA---SG-PDGVKRKVCY----------------FYD-PEVGNYYYGQGHPMKPHRIRMTHALLAHYGLL--QHMQVL-------------------------KPFPARDRDLCRFHADDYVSFLRSITPETQQD----QIRQLKRFNVGE--DC--PVFDGLYSFCQTYAGGSVGGSVKLNHGLCDIAINWAGGLHHAKKCEASGFCYVNDIVLAILELLKQHE-------------------------------------------RVLYVDIDIHH--GDGVEEAFYATDRVMTVSFHKFGDY-FPGTGHIQDIGYGSGKYYSLNVPLDDGIDDESYHLLFKP-IMGKVM----------EIFRPGA--------VVLQCG-----ADSLSGDRLGCF--NLSIKGHAECVKFMRSFNVPLLL-LGGGGYTIRNVARCWCYETGVALG--VEVEDKMPEHEYYEYFGPDYT-LHVAP-SNMENKNSRQMLEEIRNDLLHNLSKLQHAPSVPFQERPPD--T---ETPEV--------------------DED-QEDGDKR-WDPDS-------DMD--VDD---------------DR-----------KPIPS--------R---------VKREAVEPD-TKDKDG---------------------------------------------------------------------------LKGIMERGKGC----------EVEVDESG--------STKVTGVNPVGV---------EEASVKMEEEGTNKGGAEQAFPP------------------KT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [501]
'gi|14550104|gb|AAK67142.1| histone deacetylase HDA101 [Zea mays]'                                    --------------------------------------------------------------------------------------------------------------------MDPSSAGSGGNSLP--SVG-PDGQKRRVCY----------------FYD-PDVGNYYYGQGHPMKPHRIRMTHSLLARYGLL--NQMQVY-------------------------RPNPARDRDLCRFHADDYINFLRSVTPETQQD----QIRLLKRFNVGE--DC--PVFDGLYSFCQTYAGASVGGAVKLNHG-HDIAINWSGGLHHAKKCEASGFCYVNDIVLAILELLKHHE-------------------------------------------RVLYVDIDIHH--GDGVEEAFYTTDRVMTVSFHKFGDY-FPGTGDIRDIGHSKGKYYSLNVPLDDGIDDESYQSLFKP-IMGKVM----------EVFRPGA--------VVLQCG-----ADSLSGDRLGCF--NLSIKGHAECVRYMRSFNVPLLL-LGGGGYTIRNVARCWCYETGVALG--QEPEDKMPVNEYYEYFGPDYT-LHVAP-SNMENKNTRQQLDDIRSKLLDNLSKLRHAPSVHFQERVPD--T---EIPEQ--------------------DED-QDDPDER-HDPDS-------DME--VDDHKAV------EESS-RR-----------SILGI--------K---------IKREFGENA-TRVQDG---------------------------------------------------------------------------GRVASEH-RGL----------EPMAEDIG--------SSKQAPQADASAMAID-----EPSNVKNEPESSTKLQGQAAAYH------------------KP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [517]
'gi|31324093|gb|AAP47171.1| histone deacetylase HDAC1 [Oryza sativa (japonica cultivar-group)] >gi|55296516|dbj|BAD68730.1| hist'    --------------------------------------------------------------------------------------------------------------------MD-ASAGGGGNSLP--TAG-ADGAKRRVCY----------------FYD-AEVGNYYYGQGHPMKPHRIRMTHALLAHYGLL--DQMQVL-------------------------KPHPARDRDLCRFHADDYVAFLRSVTPETQQD----QIRALKRFNVGE--DC--PVFDGLYSFCQTYAGGSVGGAVKLNHG-HDIAINWAGGLHHAKKCEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYVDIDIHH--GDGVEEAFYTTDRVMTVSFHKFGDY-FPGTGDIRDIGHSKGKYYSLNVPLDDGIDDESYQSLFKP-IMGKVM----------EVFRPGA--------VVLQCG-----ADSLSGDRLGCF--NLSIRGHAECVRFMRSFNVPLLL-LGGGGYTIRNVARCWCYETGVALG--HELTDKMPPNEYFEYFGPDYT-LHVAP-SNMENKNTRQQLDDIRSRLLDNLSKLRHAPSVQFQERPPE--A---ELPEQ--------------------DED-QEDPDER-HHADS-------DVE--MDDVKPL------DDSGRRS-----------SIQNV--------R---------VKRESAETD-AADQDG---------------------------------------------------------------------------NRVAAENTKGT----------EPAADGVG--------SSKQTVPTDASAMAID-----EPGSLKVEPDNSNKLQDQPSVHQ------------------KT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [518]
'gi|55296517|dbj|BAD68731.1| putative histone deacetylase HDAC1 [Oryza sativa (japonica cultivar-group)]'                            --------------------------------------------------------------------------------------------------------------------MD-ASAGGGGNSLP--TAG-ADGAKRRVCY----------------FYD-AEVGNYYYGQGHPMKPHRIRMTHALLAHYGLL--DQMQVL-------------------------KPHPARDRDLCRFHADDYVAFLRSVTPETQQD----QIRALKRFNVGE--DC--PVFDGLYSFCQTYAGGSVGGAVKLNHG-HDIAINWAGGLHHAKKCEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYVDIDIHH--GDGVEEAFYTTDRVMTVSFHKFGDY-FPGTGDIRDIGHSKGKYYSLNVPLDDGIDDESYQSLFKP-IMGKVM----------EVFRPGA--------VVLQCG-----ADSLSGDRLGCF--NLSIRGHAECVRFMRSFNVPLLL-LGGGGYTIRNVARCWCYETGVALG--HELTDKMPPNEYFEYFGPDYT-LHVAP-SNMENKNTRQQLDDIRSRLLDNLSKLRHAPSVQFQERPPE--A---ELPEQ--------------------DED-QEDPDER-HHADS-------DVE--MDDVKPL------DDSGRRS-----------SIQNV--------R---------VKRESAETD-AADQVFFY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [460]
'gi|9022439|gb|AAF82385.1| histone deacetylase [Mesembryanthemum crystallinum]'                                    --------------------------------------------------------------------------------------------------------------------MD-----TGGNSLP---SG-PDGVKRKVSY----------------FYD-PEVGNYYYGQGHPMKPHRIRMTHALLAHYGLL--QHMQVL-------------------------KPVPARDRDLCRFHADDYVSFLRGITPEMQQD----QLRQLKRFNVGE--DC--PVFDGLYSFCQTYAGGSVGGAVKLNHGLCDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKVHE-------------------------------------------RVLYVDIDIHH--GDGVEEAFYTTERVMTVSFHKFGDY-FPGTETFVYIGYGKGKYYSLNVPLDDGIDDESYQSLFKP-IMGKVM----------EIFKPGA--------VVLQCG-----ADSLSGDRLGCF--NLSIKGHAECVKYMISFNVPLLL-VGGGGYTIRYVARCWCYETGVALG--FELDDKIPQHEYYEYFGPDYT-LHVAP-SNMENKNSRPMLDDIRGKLLEYLSSLQHAPSVQFQERPPE--A---EIPEE--------------------DED-QHDPEGR-WDPDS-------DME--VDD---------------RS-----------ISIRS--------R---------VKREIMEPD-LKDRDD---------------------------------------------------------------------------VKDAVDHPRDM----------DVSYGAGN--------TSVKAPTTSSDQ---------PEGCVEMEQDNSNRPPDQGPNMNS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [500]
lcl|Smo_HDA6_39_1_unnamed_protein_product                                    -------------------------------------------------------------------------------------------------------------------------MDGSGNSLA----SGPEGRSKRVAY----------------FYD-PEVGNYYYGQGHPMKPHRIRMTHSLLVHYGIH--NKLEVL-------------------------KPLPAKDRDLCRFHADDYVAFLRVITPETQHE----HLRALKRFNVGE--DC--PVFDGLYSFCQTYAGGSVGGAVKLNHGHSDIAVNWSGGLHHAKKCEASGFCYVNDIVLAILELLKYHA-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKFGDY-FPGTGDVRDMGHAKGKYYSLNVPLNDGIDDESYHSLFKP-IITK-------------------------------CG-----ADSLSGDRLGCF--NLSIKGHAQCVKFMRSFNVPLLL-LGGGGYTIRNVARCWCYETAVAVG--VELEDKMPYNEYYEYFGPDYT-LHVTP-SNMENQNSAQYLESIRNRLLENLSNLQHVPSVPFQERPPD--T---DLPEEVSL---------------------SVASTWR-QSPSARDDRIKKEKEELMDEGSDIDGDLPKAQQEPQD----------------------------------DQPTAMETD-AKAEEK---------------------------------------------------------------------------CSSLLPDAPSAPLASSADTAHEPNEQSTSNTNWQLVTTSTAATAAAMNARSPL-----APPALNQAPPSSTAIATAAWTPPTSATVLWSSSCCHCHCHRHGYRCYELHSGEFSSSSASSSGSSSCDRSSHTNDSLKKAIELTVLIGFGSSTRGEFTSQASSCSLKLCAQNILPDQVLEGDFSTLIQVKVANWKMAGNHELWRRDEEVKAIDRSRLTQRSIDRRIGPRIGIRRGDESGEEEELSVLPRHTKVIVTGNNRTKSVLVGLHGIVKKAVGLGGWHWL----   [727]
'gi|2665840|gb|AAC50038.1| putative histone deacetylase RPD3 [Zea mays] >gi|3023947|sp|P56521|HDAC MAIZE Probable histone deacet'    --------------------------------------------------------------------------------------------------------------------MDPSSAGSGGNSLP--SVG-PDGQKRRVCY----------------FYD-PDVGNYYYGQGHPMKPHRIRMTHSLLARYGLL--NQMQVY-------------------------RPNPARERELCRFHAEEYINFLRSVTPETQQD----QIRLLKRFNVGE--EC--PVLDGLYSFCQTYAGASVGGAVKFNHG-HDIAINWSGGLHHAKKCEASGFCYVNDIVLAILELLKHHE-------------------------------------------RVLYVDIDIHH--GDGVEEAFYTTDRVMTVSFHKFGDY-FPGTGDIRDIGHSKGKYYSLNVPLDDGIDDESYQSLFKP-IMGKVM----------EVFRPGA--------VVLQCG-----ADSLSGDRLGCF--NLSIKGHAECVRYMRSFNVPLLL-LGGGGYTIRNVARCWCYETGVALG--QEPEDKMPVNEYYEYFGPDYT-LHVAP-SNMENKNTRQQLDDIRSK----LSKLRHAPSVHFQERVPD--T---EIPEQ--------------------DED-QDDPDER-HDPDS-------DME--VDDHKAV------EESS-RR-----------SILGI--------K---------IKREFGENA-TRVQDG---------------------------------------------------------------------------GRVASEH-RGL----------EPMAEDIG--------SSKQAPQADASAMAID-----EPSNVKNEPESSTKLQGQAAAYH------------------KP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [513]
'gi|50906305|ref|XP 464641.1| putative histone deacetylase HDAC3 [Oryza sativa (japonica cultivar-group)] >gi|49387953|dbj|BAD25'    --------------------------------------------------------------------------------------------------------------------MDPSSAGAGGNSLA--SASCGDAQKRRVCY----------------FYD-PEVGNYYYGQGHPMKPHRVRMTHALLAHYGLLAPAKMQVL-------------------------RPLPARDRDLCRFHSDDYVAFLRAVTPETQFD----QIRSLRRFNVGE--DC--PVFDGLYAYCQTYAGASVGAAVKLNHGTHDIAINWSGGLHHAKKSEASGFCYVNDIVLAILELLKLHE-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTNRVMTVSFHKFGDY-FPGTGDIRDIGYSEGKYYCLNVPLDDGIDDDSYQSIFKP-IISKVM----------EMYRPGA--------VVLQCG-----ADSLSGDRLGCF--NLSGKGHAECVKFMRSFNVPLLL-LGGGGYTIRNVARCWCYETGVALG--EELREKLPYNEYYEYFGPEYS-LYVAA-SNMENRNTNKQLEEIKCNILDNLSKLQHAPSVQFEERIPE--T---KLPEP--------------------DED-QDDPDER-HDPDS-------DML--LDDHKPM------GHSA-RS-----------LIHNI--------G---------VKREITETE-TKDQHG---------------------------------------------------------------------------KRLTTEH-KVP----------EPMADDLG--------SSKQVPTADANSMAIN-----APGNAKNEPGSSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [509]
'gi|31324095|gb|AAP47172.1| histone deacetylase HDAC2 [Oryza sativa (japonica cultivar-group)]'                                    --------------------------------------------------------------------------------------------------------------------MDPSSAGAGGNSLA--SASCGDAQKRRVCY----------------FYD-PEVGNYYYGQGHPMKPHRVRMTHALLAHYGLLAPAKMQVL-------------------------RPLPARDRDLCRFHSDDYVAFLRAVTPETQFD----QIRSLRRFNVGE--DC--PVFDGLYAYCQTYAGASVGAAVKLNHGTHDIAINWSGGLHHAKKSEASGFCYVNDIVLAILELLKLHE-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTNRVMTVSFHKFGDY-FPGTGDIRDIGYSEGKYYCLNVPLDDGIDDDSYQSIFKP-IISKVM----------EMYRPGA--------VVLQCG-----ADSLSGDRLGCF--NLSGKGHAECVKFMRSFNVPLLL-LGGGGYTIRNVARCWCYETGVALG--EELREKLPYNEYYEYFGPEYS-LYVAA-SNMENRNTNKQLEEIKCNILDNLSKLQHAPSVQFEERIPE--T---KLPEP--------------------DED-QDDPDER-HDPDS-------DML--LDDHKPM------GHSA-RS-----------LIHNI--------G---------VKREITETE-TKDQHG---------------------------------------------------------------------------KRLTTEH-KVP----------EPMADDLG--------SSKQVPVSRRLLY----------------PSANP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [498]
'gi|50906299|ref|XP 464638.1| histone deacetylase HDAC3 [Oryza sativa (japonica cultivar-group)] >gi|31324097|gb|AAP47173.1| his'    --------------------------------------------------------------------------------------------------------------------MDPSSAGAGGNSLA--SASCGDAQKRRVCY----------------FYD-PEVGNYYYGQGHPMKPHRVRMTHALLAHYGLLAPAKMEVL-------------------------RPLPARGIDLCRFHSDDYVAFLRAVTPETQLG----QVRALRRFNIGP--DC--PVFDGLYAYCQTYAGASVGAAVKLNHGTHDIAINWSGGLHHAKKSEASGFCYVNDIVLAILELLKLHE-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTNRVMTVSFHKFGDY-FPGTGDIRDIGYSEGKYYCLNVPLDDGIDDDSYQSIFKP-IISKVM----------EMYRPGA--------VVLQCG-----ADSLSGDRLGCF--NLSGKGHAECVKFMRSFNVPLLL-LGGGGYTIRNVARCWCYETGVALG--EELQEKLPYNEYYEYFGPEYS-LYVAA-SNMENRNTNKQLEEIKCNILDNLSKLQHAPSVQFQERIPE--T---KLPEP--------------------DED-QEDPDER-HDPDS-------DMV--LDDHKPT------GHSA-RS-----------LIHNI--------G---------VKREITETE-TKDQHG---------------------------------------------------------------------------KRLTTEH-KGP----------EPMAEDLG--------SSKQAPTADANAVAVN-----APGNARNEPGSSPK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [510]
lcl|Smo_HDA6_5_1_unnamed_protein_product                                    -------------------------------------------------------------------------------------------------------------------------MDGSGNSLA--GSVGGDGSKRRVSY----------------FYD-PEVGNYYYGQGHPMKPHRMRMTHSLLVHYGLH--LKMEVV-------------------------EPFRARDKDLCKFHADDYVDFLKQVTPETQQE----FAKVLKRFNVGE--DC--PVFDGLYSFCQMYTGGSVGGAVRLNTNRSDIAINWSGGLHHAKKCEASGFCYVNDIVLAILELLKQHQ-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKFGDF-FPGTGDLRDVGHGKGKYYSVNVPLNEGIDDESYQRLFKP-VISKVM----------EVYQPGA--------IVLQCG-----ADSLSGDRLGCF--NLSVKGHAECVRFVRSFNVPLLL-VGGGGYT-----------TGVAVG--VELENQMPYNDYYEYFGPEYT-LLVPA-SNKENANSPEYLDSLRQQLLENISKLQHAPSVPFYERPPD--M---EPGEEM---------------------E-EDDADAR-PTR---PKPGVWNGE--PVDSDSE------GEGDVHRQRQRLPKQELDFISRKLPPSEEPA----------VKRPKFDEA-QQWQQRLRLAQLEGVLSQKSPKAIGHVLAMVKATQDKAMQNWRIG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [505]
'gi|12698880|gb|AAK01712.1| histone deacetylase HD1 [Oryza sativa]'                                    --------------------------------------------------------------------------------------------------------------------MD-ASAGGGGNSLP--TAG-ADGAKRRVCH----------------FYD-AEVGNYYCGQGHPMKPHRIRMTHALLAHYGLL--DQMQVL-------------------------KPHPARDRDLCRFHADDYVAFLRSVTPETQQD----QIRALKRFNVGE--DC--PVFDGLYSFCQTYAGGSVGGAVKLNHG-HDIAINWAGGLHHAKKCEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYVDIDIHH--GDGVEEAFYTTDRVMTVSFHKFGDY-FPGTGDIRDIGYSEGKYYCLNVPLDDGIDDDSYQSIFKP-IISKVM----------EMYRPGA--------VVLQCG-----ADSLSGDRLGCF--NLSGKGHAECVKFMRSFNVPLLL-LGGGGYAIRNVARCWCYETGVALG--HELTDKMPPNEYFEYFGPEYS-LFVAA-SNMENRNTNKQLEEIKCNILDNLSKLQHAPSVQFEERIPE--T---KLPEP--------------------DED-QEDPDER-HDPDS-------DMV--LDDHKPM------GHSA-RS-----------LIRNI--------E---------VKREITESE-AKDQHG---------------------------------------------------------------------------KRLTTEH-KGP----------EPMADDPG--------SSKQAPVSRRLLY----------------PSANP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [493]
'gi|21299237|gb|EAA11382.1| ENSANGP00000004321 [Anopheles gambiae str. PEST] >gi|31217962|ref|XP 316539.1| ENSANGP00000004321 [A'    --------------------------------------------------------------------------------------------------------------------------------------M-QSHSKKRVCY----------------YYD-SDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATADEMTKFHSDDYIRFLRSIRPDNMSE----YNKHMQRFNVGE--DC--PVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGRGKYYAVNIPLRDGMDDESYDSIFVP-IISKVM----------ETFQPSA--------VVLQCG-----ADSLTGDRLGCF--NLTVKGHGKCVEFVKKYNLPFLM-VGGGGYTIRNVSRCWTYETSVALG--VEIANELPYNDYFEYFGPDFK-LHISP-SNMSNQNTTEYLEKIKNRLFENLRMLPHAPGVQVQPIPED--A----INDESE------------------DED-KVDKDER-LPQQDKDKRIVPDNE--FSDSEDE------GEGGRRD-----------NRSFK--------GGQGAGQQQSRKRPRIEKD-GKAE-------------------------------------------------------------------------------EVKDEKE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [466]
'gi|2827430|gb|AAB99850.1| histone deacetylase 1 [Gallus gallus]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--V---MQGTKRKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSAGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VISKVM----------ETFQPSA--------VVLQCG-----SDSLSGDRLGCF--NLTIKGHAKCVEFVKSFNLPMLM-LGGGGYTIRNVARCWTYETAVALD--TEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQPIPED--A----VQEDSG------------------DEE-EEDPEKR-ISIRNSDKRISCDEE--FSDSEDE------GEGGRKN-----------VANFK--------K---------AKRVKTEEE-KEE--E----------------------------------------------------------------------EKK----DEKEEEKAK----------------E---E----KAEPKG------VKE---ET-------KST----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [480]
'gi|2829214|gb|AAC00504.1| erythrocyte histone deacetylase [Gallus gallus] >gi|2791684|gb|AAB96923.1| histone deacetylase-1; HD-'    --------------------------------------------------------------------------------------------------------------------------------MA--L---TQGTKRKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSAGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VISKVM----------ETFQPSA--------VVLQCG-----SDSLSGDRLGCF--NLTIKGHAKCVEFVKSFNLPMLM-LGGGGYTIRNVARCWTYETAVALD--TEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQPIPED--A----VQEDSG------------------DEE-EEDPEKR-ISIRNSDKRISCDEE--FSDSEDE------GEGGRKN-----------VANFK--------K---------AKRVKTEEE-KEE--E----------------------------------------------------------------------EKK----DEKEEEKAK----------------E---E----KAEPKG------VKE---ET-------KST----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [480]
'gi|51703484|gb|AAH81054.1| Hdac2 protein [Xenopus laevis]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--Y-T-QGGAKKKVCY----------------YYD-GDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATAEEMTKYHSDEYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKP-IISKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTVKGHAKCVEVVKTFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--CEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VQEDSG------------------DEE-GEDPDKR-ISIRASDKRIACDEE--FSDSEDE------GEGGRRN-----------VADHK--------KG--------AKKARLEED-KKETDD----------------------------------------------------------------------KKS----DVKEEDKSK----------------DNIAE----KMDTKG------VKS---EQ-------PINP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [488]
'gi|3659524|gb|AAC61494.1| putative histone deacetylase [Drosophila melanogaster]'                                    --------------------------------------------------------------------------------------------------------------------------------------M-QSHSKKRVCY----------------YYD-SDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATADEMTKFHSDEYVRFLRSIRPDNMSE----YNKQMQRFNVGE--DC--PVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVP-IISKVM----------ETFQPAA--------VVLQCG-----ADSLTGDRLGCF--NLTVKGHGKCVEFVKKYNLPFLM-VGGGGYTIRNVSRCWTYETSVALA--VEIANELPYNDYFEYFGPDFK-LHISP-SNMTNQNTSEYLEKIKNRLFENLRMLPHAPGVQIQAIPED--A----INDESD------------------DED-KVDKDDR-LPQSDKDKRIVPENE--YSDSEDE------GEGGRRD-----------NRSYK--------GQ--------RKRPRLDKD-TNSNK-----------------------------------------------------------------------ASSETSSEIKDEKEKG----------------DGADG----EESTASNTNSNNNSN---NKSDNDAGATANAGSGSGTGSGAGAKGAKENNI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [521]
'gi|24657891|ref|NP 647918.2| Rpd3 CG7471-PA [Drosophila melanogaster] >gi|16197909|gb|AAL13716.1| GM14158p [Drosophila melanoga'    --------------------------------------------------------------------------------------------------------------------------------------M-QSHSKKRVCY----------------YYD-SDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATADEMTKFHSDEYVRFLRSIRPDNMSE----YNKQMQRFNVGE--DC--PVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVP-IISKVM----------ETFQPAA--------VVLQCG-----ADSLTGDRLGCF--NLTVKGHGKCVEFVKKYNLPFLM-VGGGGYTIRNVSRCWTYETSVALA--VEIANELPYNDYFEYFGPDFK-LHISP-SNMTNQNTSEYLEKIKNRLFENLRMLPHAPGVQIQAIPED--A----INDESD------------------DED-KVDKDDR-LPQSDKDKRIVPENE--YSDSEDE------GEGGRRD-----------NRSYK--------GQ--------RKRPRLDKD-TNSNK-----------------------------------------------------------------------ASSETSSEIKDEKEKG----------------DGADG----EESTASNTNSNNNSN---NKSDNDAGATANAGSGSGSGSGAGAKGAKENNI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [521]
'gi|32450592|gb|AAH54208.1| Hdac2 protein [Xenopus laevis]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--Y-T-QGGAKKKVCY----------------YYD-GDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATAEEMTKYHSDEYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKP-IISKVM----------EMYQPSA--------VVLQCG-----PDSLSGDRLGCF--NLTVKGHAKCVEVVKTFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--CEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VQEDSG------------------DEE-GEDPDKR-ISIRASDKRIACDEE--FSDSEDE------GEGGRRN-----------VADHK--------KK--------KKKKKK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [447]
'gi|89268122|emb|CAJ81536.1| histone deacetylase 2 [Xenopus tropicalis]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--Y-T-QGGAKKKVCY----------------YYD-GDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATAEEMTKYHSDEYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKP-IISKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTVKGHAKCVEVVKTFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--CEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VQEDSG------------------DEE-GEDPDKR-ISIRASDKRIACDEE--FSDSEDE------GEGGRRN-----------VADHK--------KG--------AKKARLEED-KKETDD----------------------------------------------------------------------KKS----DVKEEDKSK----------------DNIAE----KMDTKG------VKS---EQ-------PSNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [488]
'gi|49257716|gb|AAH74509.1| Histone deacetylase 1 [Xenopus tropicalis] >gi|53749670|ref|NP 001005432.1| histone deacetylase 1 [X'    --------------------------------------------------------------------------------------------------------------------------------MA--Y-T-QGGAKKKVCY----------------YYD-GDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATAEEMTKYHSDEYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKP-IISKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTVKGHAKCVEVVKTFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--CEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VQEDSG------------------DEE-GEDPDKR-ISIRASDKRIACDEE--FSDSEDE------GEGGRRN-----------VADHK--------KG--------AKKARLEEE-KKETDD----------------------------------------------------------------------KKS----DVKEEDKSK----------------DNIAE----KMDTKG------VKS---EQ-------PSNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [488]
'gi|54641397|gb|EAL30147.1| GA20378-PA [Drosophila pseudoobscura]'                                    --------------------------------------------------------------------------------------------------------------------------------------M-QSHSKKRVCY----------------YYD-SDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATADEMTKFHSDEYVRFLRSIRPDNMTE----YNKQMQRFNVGE--DC--PVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVP-IISKVM----------ETFQPAA--------VVLQCG-----ADSLTGDRLGCF--NLTVKGHGKCVDFVKKYNLPFLM-VGGGGYTIRNVSRCWTYETSVALA--VDIANELPYNDYFEYFGPDFK-LHISP-SNMTNQNTSEYLEKIKNRLFENLRMLPHAPGVQIQAIPED--A----INDESD------------------DED-KVDKDDR-LPQSDKDKRIVPENA--YSDSEDE------GEGGRRD-----------NRAYK--------GQ--------RKRPRLDKD-NNSNK-----------------------------------------------------------------------ASSEVSSEIKDEKEKV----------------DGADG----EESTASN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [480]
'gi|81294220|gb|AAI08089.1| Histone deacetylase 1 [Bos taurus] >gi|82697313|ref|NP 001032521.1| histone deacetylase 1 [Bos tauru'    --------------------------------------------------------------------------------------------------------------------------------MA--Q---TQGTKRKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VMSKVM----------EMFQPSA--------VVLQCG-----SDSLSGDRLGCF--NLTIKGHAKCVEFVKSFNLPMLM-LGGGGYTIRNVARCWTYETAVALD--TEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPED--A----IPEESG------------------DED-EEDPDKR-ISICSSDKRIACEEE--FSDSDEE------GEGGRKN-----------SSNFK--------K---------AKRVKTEDE-KEKDPE----------------------------------------------------------------------EKK----EVTEEEKTK----------------E---E----KQEAKG------VKE---EV-------KLA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [482]
'gi|6680193|ref|NP 032254.1| histone deacetylase 1 [Mus musculus] >gi|1771286|emb|CAA66870.1| histone deacetylase [Mus musculus]'    --------------------------------------------------------------------------------------------------------------------------------MA--Q---TQGTKRKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VMSKVM----------EMFQPSA--------VVLQCG-----SDSLSGDRLGCF--NLTIKGHAKCVEFVKSFNLPMLM-LGGGGYTIRNVARCWTYETAVALD--TEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPED--A----IPEESG------------------DED-EEDPDKR-ISICSSDKRIACEEE--FSDSDEE------GEGGRKN-----------SSNFK--------K---------AKRVKTEDE-KEKDPE----------------------------------------------------------------------EKK----EVTEEEKTK----------------E---E----KPEAKG------VKE---EV-------KLA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [482]
'gi|67678279|gb|AAH97943.1| Histone deacetylase 1 [Rattus norvegicus] >gi|70794768|ref|NP 001020580.1| histone deacetylase 1 [Ra'    --------------------------------------------------------------------------------------------------------------------------------MA--Q---TQGTKRKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VMSKVM----------EMFQPSA--------VVLQCG-----SDSLSGDRLGCF--NLTIKGHAKCVEFVKSFNLPMLM-LGGGGYTIRNVARCWTYETAVALD--TEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPED--A----IPEESG------------------DED-EEDPDKR-ISICSSDKRIACEEE--FSDSDEE------GEGGRKN-----------SSNFK--------K---------AKRVKTEDE-KEKDPE----------------------------------------------------------------------EKK----EVTEEEKTK----------------E---E----KPEAKG------VKE---EV-------KMA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [482]
'gi|87162464|ref|NP 032255.2| histone deacetylase 2 [Mus musculus]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--Y-S-QGGGKKKVCY----------------YYD-GDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATAEEMTKYHSDEYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKP-IISKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTVKGHAKCVEVVKTFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--CEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VHEDSG------------------DED-GEDPDKR-ISIRASDKRIACDEE--FSDSEDE------GEGGRRN-----------VADHK--------KG--------AKKARIEED-KKETED----------------------------------------------------------------------KKT----DVKEEDKSK----------------DNSGE----KTDPKG------AKS---EQ-------LSNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [488]
'gi|55961192|emb|CAI15363.1| HDAC2 [Homo sapiens] >gi|55960368|emb|CAI14207.1| HDAC2 [Homo sapiens] >gi|68068066|sp|Q92769|HDAC2'    --------------------------------------------------------------------------------------------------------------------------------MA--Y-S-QGGGKKKVCY----------------YYD-GDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATAEEMTKYHSDEYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKP-IISKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTVKGHAKCVEVVKTFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--CEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VHEDSG------------------DED-GEDPDKR-ISIRASDKRIACDEE--FSDSEDE------GEGGRRN-----------VADHK--------KG--------AKKARIEED-KKETED----------------------------------------------------------------------KKT----DVKEEDKSK----------------DNSGE----KTDTKG------TKS---EQ-------LSNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [488]
'gi|82994453|ref|XP 930837.1| PREDICTED: skip [Mus musculus]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--Q---TQGTKRKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEATFKP-VMSKVM----------EMFQPSA--------VVLQCG-----SDSLSGDRLGCF--NLTIKGHAKCVEFVKSFNLPMLM-LGGGGYTIRNVARCWTYETAVALD--TEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPED--A----IPEESG------------------DED-EEDPDKR-ISICSSDKRIACEEE--FSDSDEE------GEGGRKN-----------SSNFK--------K---------AKRVKTEDE-KEKDPE----------------------------------------------------------------------EKK----EVTEEEKTK----------------E---E----KPEAKG------VKE---EV-------KLA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [482]
'gi|62666128|ref|XP 342150.2| PREDICTED: histone deacetylase 2 [Rattus norvegicus]'                                    MVISYHKLSRNKPSSLFPDIFKSGSGDLCFPLRAAAVVPPNSQPRRPEAYPCRVSRVGAAANPALRSRALPAPARRPAPGCPCCEGRRARRLPQPSCLAAGPRRARAAGGGAAARRRRP-------EPMA--Y-S-QGGGKKKVCY----------------YYD-GDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATAEEMTKYHSDEYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAVLELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKP-IISKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTVKGHAKCVEVVKTFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--CEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VHEDSG------------------DED-GEDPDKR-ISIRASDKRIACDEE--FSDSEDE------GEGGRRN-----------VADHK--------KG--------AKKARIEED-KKEAED----------------------------------------------------------------------KRT----DVKEEDKSK----------------DNSGE----KTDTKG------AKS---EQ-------LNNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [609]
'gi|30583783|gb|AAP36140.1| Homo sapiens histone deacetylase 1 [synthetic construct] >gi|61369536|gb|AAX43347.1| histone deacety'    --------------------------------------------------------------------------------------------------------------------------------MA--Q---TQGTRRKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VMSKVM----------EMFQPSA--------VVLQCG-----SDSLSGDRLGCF--NLTIKGHAKCVEFVKSFNLPMLM-LGGGGYTIRNVARCWTYETAVALD--TEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPED--A----IPEESG------------------DED-EDDPDKR-ISICSSDKRIACEEE--FSDSEEE------GEGGRKN-----------SSNFK--------K---------AKRVKTEDE-KEKDPE----------------------------------------------------------------------EKK----EVTEEEKTK----------------E---E----KPEAKG------VKE---EV-------KLAL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [483]
'gi|55630864|ref|XP 519834.1| PREDICTED: similar to histone deacetylase 1; reduced potassium dependency, yeast homolog-like 1 [P'    --------------------------------------------------------------------------------------------------------------------------------MA--Q---TQGTRRKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VMSKVM----------EMFQPSA--------VVLQCG-----SDSLSGDRLGCF--NLTIKGHAKCVEFVKSFNLPMLM-LGGGGYTIRNVARCWTYETAVALD--TEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPED--A----IPEESG------------------DED-EEDPDKR-ISICSSDKRIACEEE--FSDSEEE------GEGGRKN-----------SSNFK--------K---------AKRVKTEDE-KEKDPE----------------------------------------------------------------------EKK----EVTEEEKTK----------------E---E----KPEAKG------VKE---EV-------KLA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [482]
'gi|12653071|gb|AAH00301.1| Histone deacetylase 1 [Homo sapiens] >gi|48479080|gb|AAT44863.1| histone deacetylase 1 [Homo sapiens'    --------------------------------------------------------------------------------------------------------------------------------MA--Q---TQGTRRKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VMSKVM----------EMFQPSA--------VVLQCG-----SDSLSGDRLGCF--NLTIKGHAKCVEFVKSFNLPMLM-LGGGGYTIRNVARCWTYETAVALD--TEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPED--A----IPEESG------------------DED-EDDPDKR-ISICSSDKRIACEEE--FSDSEEE------GEGGRKN-----------SSNFK--------K---------AKRVKTEDE-KEKDPE----------------------------------------------------------------------EKK----EVTEEEKTK----------------E---E----KPEAKG------VKE---EV-------KLA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [482]
'gi|73949981|ref|XP 544435.2| PREDICTED: similar to histone deacetylase 1 isoform 1 [Canis familiaris]'                              --------------------------------------------------------------------------------------------------------------------------------MA--Q---TQGTRRKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VMSKVM----------EMFQPSA--------VVLQCG-----SDSLSGDRLGCF--NLTIKGHAKCVEFVKSFNLPMLM-LGGGGYTIRNVARCWTYETAVALD--TEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQVIPED--A----IPEESG------------------DED-EEDPDKR-ISICSSDKRIACEEE--FSDSDEE------GEGGRKN-----------SSNFK--------K---------AKRVKTEDE-KEKDPE----------------------------------------------------------------------EKK----EVTEEEKTK----------------E---E----KQEAKG------VKE---EV-------KLA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [482]
'gi|3023934|sp|P70288|HDAC2 MOUSE Histone deacetylase 2 (HD2) (YY1 transcription factor-binding protein) >gi|1667396|gb|AAC52889'    --------------------------------------------------------------------------------------------------------------------------------MA--Y-S-QGGGKKKVCY----------------YYD-GDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATAEEMTKYHSDEYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKP-IISKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTVKGHAKCVEVAKTFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--CEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VHEDSG------------------DED-GEDPDKR-ISIRASDKRIACDEE--FSDSEDE------GEGGRRN-----------VADHK--------KG--------AKKARIEED-KKETED----------------------------------------------------------------------KKT----DVKEEDKSK----------------DNSGE----KTDPKG------AKS---EQ-------LSNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [488]
'gi|2583090|gb|AAC23917.1| putative histone deacetylase HDAC1 [Drosophila melanogaster]'                                    --------------------------------------------------------------------------------------------------------------------------------------M-QSHSKKRVCY----------------YYD-SDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATADEMTKFHSDEYVRFLRSIRPDNMSE----YNKQMQRFNVGE--NC--PVFDGLYDFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVP-IISKVM----------ETFQPAA--------VVLQCG-----ADSLTGDRLGCF--NLTVKGHGKCVEFVKKYNLPFLMVVGGGGYTIRKVSRCWTYETSVALA--VEIANELPYNDYFEYFGPDFK-LHISP-SNMTNQNTSEYLEKIKNRLFENLRMVPHAPGVQIQAIPED--A----INDESD------------------DED-KVDKDDR-LPQSDKDKRIVPENE--YSDSEDE------GEGGRRD-----------NRSYK--------GQ--------RKRPRLDKD-TNSNK-----------------------------------------------------------------------ASSETSSEIKDEKEKG----------------DGADG----EESTASNTNSNNNSN---NKSDNDAGATANAGSGSGTGSGAGAKGAKENNI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [522]
'gi|60654411|gb|AAX29896.1| histone deacetylase 2 [synthetic construct]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--Y-S-QGGGKKKVCY----------------YYD-GDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATAEEMTKYHSDEYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKP-IISKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTVKGHAKCVEVVKTFNLPLLM-LGGGGYTIRNVARCWTHETAVALD--CEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VHEDSG------------------DED-GEDPDKR-ISIRASDKRIACDEE--FSDSEDE------GEGGRRN-----------VADHK--------KG--------AKKARIEED-KKETED----------------------------------------------------------------------KKT----DVKEEDKSK----------------DNSGE----KTDTKG------TKS---EQ-------LSNPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [489]
'gi|71051977|gb|AAH31055.2| HDAC2 protein [Homo sapiens]'                                    F-----------------------------------------GGPLLASWCRCHLRFRAFGTSAGWYRAFPAPPPLLPPACPSPRDYR----PHVSLSHFLSRPSRGGSSSSSSSRRRSPVAAVAGEPMA--Y-S-QGGGKKKVCY----------------YYD-GDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATAEEMTKYHSDEYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKP-IISKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTVKGHAKCVEVVKTFNLPLLM-LGGGGYTIRNVARCWTHETAVALD--CEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VHEDSG------------------DED-GEDPDKR-ISIRASDKRIACDEE--FSDSEDE------GEGGRRN-----------VADHK--------KG--------AKKARIEED-KKETED----------------------------------------------------------------------KKT----DVKEEDKSK----------------DNSGE----KTDTKG------TKS---EQ-------LSNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [571]
'gi|60688073|gb|AAH90604.1| Hdac1 predicted-prov protein [Xenopus tropicalis] >gi|71896231|ref|NP 001025564.1| hdac1 predicted-p'    --------------------------------------------------------------------------------------------------------------------------------MA--L---SQGTKKKVCY----------------YYD-GDVGNYYYGQGHPIKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKASAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASSVKLNKQQTDISVNWSGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VMSKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTIKGHAKCVEFIKTFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--SEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPED--S----VHDDSG------------------EED-EEDPDKR-ISIRSSDKRIACDEE--FSDSEDE------GEGGRRN-----------VASFK--------K---------VKRVKTEEE-KDG--E----------------------------------------------------------------------EKK----DVKEEEKPK----------------D---E----KTDSKR------VKE---ET-------KSA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [480]
'gi|55716026|gb|AAH85375.1| Histone deacetylase 1 [Danio rerio]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--L-S-SQGTKKKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSAGGSVAGAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-IMSKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTIKGHAKCVEYMKSFNLPLLM-LGGGGYTIRNVARCWTFETAVALD--STIPNELPYSDYFEYFGPDFK-LHISP-SNMTNQNTNDYLEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VQEDSG------------------DEE--DDPDKR-ISIRAHDKRIACDEE--FSDSEDE------GQGGRRN-----------AANYK--------K---------PKRVKTEEE-KDG--E----------------------------------------------------------------------EKK----DVKEEEKAS----------------E---E----KMDTKG------PKE---EL-------KTV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [480]
lcl|Smo_HDA6_36_2_unnamed_protein_product                                    -------------------------------------------------------------------------------------------------------------------------MDGSGNSLA--GSVGGDGSKRRVSY----------------FYD-PEVGNYYYGQGHPMKPHRMRMTHSLLVHYGLH--LKMEVV-------------------------EPFRARDKDLCKFHADDYVDFLKQVTPETQQE----FAKVLKRFNVGE--DC--PVFDGLYSFCQMYTGGSVGGAVRLNTNRSDIAINWSGGLHHAKKCEASGFCYVNDIVLAILELLKQHQ-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKFGDF-FPGTGDLRDVGHGKGKYYSVNVPLNEGIDDESYQRLFKP-VISKVM----------EVYQPGA--------IVLQCG-----ADSLSGDRLGCF--NLSVKGHAECVRFVRSFNVPLLL-VGGGGYT-----------TGVAVG--VELENQMPYNDYYEYFGPEYT-LLVPA-SNKENANSPEYLDSLRQQLLENISKLQHAPSVPFYERPPD--M---EPGEEMVLMSFEIPELLLTLCS---FQE-ENDADAR-PTK---PKPGVWNGE--PVDSDSE------GEGDVHR--QRLPKQELDFISRKLPPSEEPV----------VKRPKFDER-TEEQRDDDIATSLSLGPAMAAEIKISS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [503]
'gi|66515540|ref|XP 394976.2| PREDICTED: similar to ENSANGP00000004321 [Apis mellifera]'                                    ------------------------------------------------------------------------------------------------------------------------------------MSALPHISRENILHVQRDCQNVFVISALNIYIL-GDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATADEMTKFHSDDYIRFLRSIRPDNMSE----YNKQMQRFNVGE--DC--PVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNIPLRDGMDDESYESIFVP-IISKVM----------ETFQPSA--------VVLQCG-----ADSLTGDRLGCF--NLTVRGHGKCVEFVKKYNLPFLM-VGGGGYTIRNVSRCWTYETSVALG--SEIANELPYNDYFEYFGPDFK-LHISP-SNMANQNTPEYLEKIKTRLFENLRMLPHAPGVQVQSIPEDG-A----VIEDSE------------------AEE-KVNPDER-LPQRDLDKRIQHENE--YSDSEEE------GEGGRRD-----------NRSFK--------GS--------RKRPRLEKG-QEENEK---------------------------------------------------------------------DEKT----NITNEETKK----------------DGGANP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [492]
'gi|1665723|dbj|BAA08909.1| RPD3 protein [Homo sapiens] >gi|60819522|gb|AAX36503.1| histone deacetylase 1 [synthetic construct]'     --------------------------------------------------------------------------------------------------------------------------------MA--Q---TQGTRRKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VMSKVM----------EMFQPSA--------VVLQCG-----SDSLSGDRLGCF--NLTIKGHAKCVEFVKSFNLPMLM-LGGGGYTIRNVARCRTYETAVALD--TEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPED--A----IPEESG------------------DED-EDDPDKR-ISICSSDKRIACEEE--FSDSEEE------GEGGRKN-----------SSNFK--------K---------AKRVKTEDE-KEKDPE----------------------------------------------------------------------EKK----EVTEEEKTK----------------E---E----KPEAKG------VKE---EV-------KLA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [482]
'gi|19526271|gb|AAL89665.1| histone deacetylase [Takifugu rubripes]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--L-T-SQGTKKKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANGEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSVGGSVAGAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-IMAKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTIKGHAKCVEYMKSFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--ASIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNDYLEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VQEDSG------------------DEE-AEDHNKR-ISIRAHDKRIACEEE--FSDSEDE------GEGGRRN-----------SVSFK--------K---------AKRAKTEGE-KEGEEK----------------------------------------------------------------------EKK----EVKEEEKVP----------------E---E----------------PKE---ES-------KTP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [477]
'gi|3023928|sp|O42227|HDA1B XENLA Probable histone deacetylase 1-B (HD1) (RPD3 homolog) >gi|2444430|gb|AAC60346.1| deacetylase ['    --------------------------------------------------------------------------------------------------------------------------------MA--L---SQGTKKKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKASAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASAVKLNKQQTDISVNWSGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVVYIDIDIHH--GDGVEEAFYTTDRVMSVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VMTKVM----------EMFQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTIKGHAKCVEFIKTFNLPMLM-LGGGGYTIRNVARCWTYETAVALD--SEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPED--S----VHDDSG------------------EED-EEDPDKR-ISIRSSDKRIACDEE--FSDSEDE------GEGGRKN-----------VANFK--------K---------VKRVKTEEE-KEG--E----------------------------------------------------------------------DKK----DVKEEEKAK----------------D---E----KTDSKR------VKE---ET-------KSV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [480]
'gi|27735466|gb|AAH41296.1| MGC53583 protein [Xenopus laevis]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--L---SQGTKKKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKASAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASAVKLNKQQTDISVNWSGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVVYIDIDIHH--GDGVEEAFYTTDRVMSVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VMTKVM----------EMFQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTIKGHAKCVEFIKTFNLPMLM-LGGGGYTIRNVARCWTYETAVALD--SEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPED--S----VHDDSG------------------EED-EEDPDKR-ISIRSSDKRIACDEE--FSDSEDE------GEGGRRN-----------MASFK--------K---------LKRVKTEEE-KEA--D----------------------------------------------------------------------DKK----DVKEEEKLK----------------D---D----KTDSKR------VKE---ET-------KSA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [480]
'gi|51704120|gb|AAH81136.1| AB21 protein [Xenopus laevis] >gi|602098|emb|CAA55211.1| yeast RPD3 homologue [Xenopus laevis] >gi|3'    --------------------------------------------------------------------------------------------------------------------------------MA--L---TLGTKKKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIF-------------------------RPHKASAEDMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSAGGSVASAVKLNKQQTDISVNWSGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVVYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYALRDGIDDESYEAIFKP-VMSKVM----------EMFQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTIKGHAKCVEFIKTFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--SEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAVAED--S----IHDDSG------------------EED-EDDPDKR-ISIRSSDKRIACDEE--FSDSEDE------GEGGRKN-----------VANFK--------K---------VKRVKTEEE-KEG--E----------------------------------------------------------------------DKK----DVKEEEKAK----------------D---E----KTDSKR------VKE---ET-------KSV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [480]
'gi|1666637|emb|CAA70455.1| histone deacetylase [Drosophila melanogaster]'                                    --------------------------------------------------------------------------------------------------------------------------------------M-QSHSKKRVCY----------------YYD-SDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMDI--------------------------RPHKATADEMTKFHCDEYVRFLRSIRPDNMSE----YNKQMQRFNVGE--DC--PVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVP-IISKVM----------ETFQPAA--------VVLQCG-----ADSLTGDRLGCF--NLTVKGHGKCVEFVKKYNLPFLM-VGGGGYTIRKVSRCWTYETSVALA--VEIANELPYNDYFEYFGPDFK-LHISP-SNMTNQNTSEYLEKIKNRLFENLRMLPHAPGVQIQAIPED--A----INDESD------------------DED-KVDKDDR-LPQSDKDKRIVPENE--YSDSEDE------GEGGRRD-----------NRSYK--------GQ--------RKRPRLDKD-TNSNK-----------------------------------------------------------------------ASSETSSEIKDEKEKG----------------DGADG----EESTASNTNSNNNSN---NKSDNDAGATANAGSGSGSGSGAGAKGAKENNI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [520]
'gi|27545221|ref|NP 775343.1| histone deacetylase 1 [Danio rerio] >gi|21105403|gb|AAM34645.1| histone deaceytlase 1 [Danio rerio'    --------------------------------------------------------------------------------------------------------------------------------MA--L-S-SQGTKKKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVAGAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-IMSKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTIKGHAKCVEYMKSFNLPLLM-LGGGGYTIKNVARCWTFETAVALD--STIPNELPYNDYFEYFGPDFK-LHISP-FNMTNQNTNDYLEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VQEDSG------------------DEE--DDPDKR-ISIRAHDKRIACDEE--FSDSEDE------GQGGRRN-----------AANYK--------K---------PKRVKTEEE-KDG--E----------------------------------------------------------------------EKK----DVKEEEKAS----------------E---E----KMDTKG------PKE---EL-------KTV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [480]
'gi|4557641|ref|NP 001518.1| histone deacetylase 2 [Homo sapiens] >gi|1667394|gb|AAC50814.1| transcriptional regulator homolog R'    --------------------------------------------------------------------------------------------------------------------------------MA--Y-S-QGGGKKKVCY----------------YYD-GDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATAEEMTKYHSDEYIKFLRSIRPDNMSE----YSKQMHIFNVGE--DC--PAFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKYEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMCDGIDDESYGQIFKP-IISKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTVKGHAKCVEVVKTFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--CEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VHEDSG------------------DED-GEDPDKR-ISIRASDKRIACDEE--FSDSEDE------GEGGRRN-----------VADHK--------KG--------AKKARIEED-KKETED----------------------------------------------------------------------KKT----DVKEEDKSK----------------DNSGE----KTDTKG------TKS---EQ-------LSNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [488]
'gi|73974025|ref|XP 532270.2| PREDICTED: similar to Histone deacetylase 2 (HD2) [Canis familiaris]'                                  --------------------------------------------------------------------------------------------------------------------------------MP------------TVKY----------------FWDASDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATAEEMTKYHSDEYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKP-IISKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTVKGHAKCVEVVKTFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--CEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VHEDSG------------------DED-GEDPDKR-ISIRASDKRIACDEE--FSDSEDE------GEGGRRN-----------VADHK--------KG--------AKKARIEED-KKETED----------------------------------------------------------------------KKA----DVKEEDKSK----------------DSSGE----KTDTKG------AKS---EQ-------LSNP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [481]
'gi|47551069|ref|NP 999711.1| histone deacetylase [Strongylocentrotus purpuratus] >gi|2654077|gb|AAB87685.1| histone deacetylase'    --------------------------------------------------------------------------------------------------------------------------------M-----A-STGTKKRVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLILNYGLY--RKMEIY-------------------------RPHKAVMEEMTKYHSDDYVKFLRTIRPDNMSE----YTKQMQRFNVGE--DC--PVFDGLYEFCQLSSGGSVAGAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPLRDGIDDESYDKIFKP-IMCKVM----------EMYQPSA--------ICLQCG-----ADSLSGDRLGCF--NLTLKGHAKCVEFMKQYNLPLLL-MGGGGYTIRNVARCWTYETSTALG--VEIANELPYNDYFEYFGPDFK-LHISP-SNMTNQNTGEYLDKIKTRLYENMRMIPHAPGVQMQPIPED--A----IPDDSD------------------AEDEAENPDKR-ISIMAQDKRIQRDDE--FSDSEDEGETRLPGEGGRRD-----------HRSHK------------------AKRSKIDDS-PGKEAD----------------------------------------------------------------------KEA----KSSDASKEA----------------KPAAEPQAVPMDTTP------APP---PKKSEDKPEASKPTEVKAKPAEKEPGEGEASPA------------DL------VVPVPKVSAPSEGATLPAVTIPPSSGTSQPPADPPVSAPTPTPASAPAEKQD-------------------------------------------------------------------------------------------------------------------------------   [576]
'gi|62655265|ref|XP 576595.1| PREDICTED: histone deacetylase 1 [Rattus norvegicus]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--Q---TQGTERKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHYAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHHGDGDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VMSKVM----------EMFQPSA--------VVLQCG-----SDSLSGDRLGCF--NLTIKGHAKCVEFVKSFNLPMLM-LGGDGYTIHNVARCWTYETAVALD--TEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIKQRLFENLRMLPHTPGVQMQAIPED--A----IPEESG------------------DED-EEDPDKP-ISICSSDKCIACEEE--FPDSDEE------GEGGREN-----------SSNFK--------K---------AKRVKTEDE-KEKDPE----------------------------------------------------------------------EKK----EVTEEEKTK----------------E---E----KPEAKG------VKE---EV-------KMA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [484]
'gi|47213589|emb|CAF93492.1| unnamed protein product [Tetraodon nigroviridis]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--YTT-ATGTKKKVCY----------------YYD-GDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKATAEEMTKYHSDDYIKFLRSIRPDNMSE----FSKQMQRFNVGE--DC--PVFDGLFEFCQLSAGGSAAGSVKLNRQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPLRDGIDDESYEHIFKP-VMAKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTIRGHAKCVEYMKSFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--TDIPDELPYNDYFEYFGPDFKAAHSVH-RNMTNQNTQEYMDKIKQRLFENLRMLPHAPGVQMQAIPED--A----VPDDNV------------------DED-TEDPDKR-LSIRATDKRIACDEE--FSDSEDE------GEGGRKN-----------VANHK--------KG--------AKRPRVDED-KKDGEE----------------------------------------------------------------------KKI----EIKEEENTK----------------DISAE----KTDSKS------VKT---EQ-------TTSA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [490]
'gi|72026657|ref|XP 798972.1| PREDICTED: similar to histone deacetylase 1 [Strongylocentrotus purpuratus]'                           -----------------------------------------------------------------------------------------------------------------------------------------------MFF----------------NFS-GDVGNYYYGQGHPMKPHRIRMTHNLILNYGLY--RKMEIY-------------------------RPHKAVMEEMTKYHSDDYVKFLRTIRPDNMSE----YTKQMQRFNVGE--DC--PVFDGLYEFCQLSSGGSVAGAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPLRDGIDDESYDKIFKP-IMCKVM----------EMYQPSA--------ICLQCG-----ADSLSGDRLGCF--NLTLKGHAKCVEFMKQYNLPLLL-MGGGGYTIRNVARCWTYETSTALG--VEIANELPYNDYFEYFGPDFK-LHISP-SNMTNQNTGEYLDKIKTRLYENMRMIPHAPGVQMQPIPED--A----IPDDSD------------------AEDEAENPDKR-ISIMAQDKRIQRDDE--FSDSEDEGETRLPGEGGRRD-----------HRSHK------------------AKRSKIDDS-PGKEAD----------------------------------------------------------------------KGE----QICSV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [458]
'gi|19070647|gb|AAL83942.1| putative histone deacetylase [Physarum polycephalum]'                                    ----------------------------------------------------------------------------------------------------------------------------------------MASNKPKVAY----------------FYD-ADVGNYYYGQGHPMKPHRIRMTHNLLLNYGPY--KKMQIY-------------------------RPRRATELDMTKFHSDDYIQFLRLVSPDNMNE----YAKQLQRFNVVE--DC--PIFEGMFNFFQISAGGSVGGAVKLNNNDANVAMNWAGGLHQAKKSEASGFCYVNDIVLAILELLKHHQ-------------------------------------------RILYIDVDIHH--GDGVEEAFYTTDRVMTVSFHKFGDY-FPGTGDIRDVGAGKGKYYAVNFPLKDGIDDESYQSVFKP-IIQAVI----------EFYRPGA--------IVFQSG-----AHSLSGDRLGGF--NLSIRGHAECLTFLKQFNLPLLV-LGGGGYTIRNVARCWAYDTGVVLD--TELDDELPYNDYLEYFGPDYR-LHYTP-NNMENQNGREYLEKCKNKILENLRHLQNAPGVAMHEVPPD--A-----MDDSD------------------DSD-DDDPDSR-QNQRDLDRRVSHEDN--LSDSDEE--------DGRRNMEDEPNGGYSSSNSHR--------A---------SRRKRTGKI-SIMAGD--------------KERAPMSRNARSVIPPPHSPISTHGSTLIPPHSPVPPPVDDDDMVDAEEAEVDIQGDSGEVPFSTNNNNNNTNNNGNSNNNNNNNNNINTNNNDNNMTSNATTTTSTTNADNNSNNSTKS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [579]
'gi|66828287|ref|XP 647498.1| hypothetical protein DDB0189724 [Dictyostelium discoideum] >gi|60475530|gb|EAL73465.1| hypothetica'    ------------------------------------------------------------------------------------------------------------------------------------------MSTRKVSY----------------FYD-NEVGNHYYGPNHPMKPHRMRMTHDLVLNYGIY--KKMQIF-------------------------RPRKASELELTNFHSDDYINFLKLVTPDNMHD----YSKQLVKFNVRE--DC--PVFDGMYNFCQISSGGSIGCAVKVNSKESDVAINWAGGLHHAKKSEASGFCYTNDIVLSILELLKHHE-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGDY-FPGTGDVKDIGADKGKYYSLNFPLKDGIDDESYQSIFRP-IIRSVM----------DFYRPGA--------VVIQCG-----ADSLTGDRLGCF--NLTLRGHAQCIEFLKSFNVPLVV-LGGGGYTIKNVARCWTYETSILVD--SELKDELPYNDYLEYYGPEYR-LHITP-NNMENQNTKDYLEKLKIQLLENLRNLNHAPAAAHHDIPPD--S-----FNYSD------------------DED-DEDPDVR-ISEADRDKKVHHQGE--LSDSDEE--------DGRRN-----------YSNGLEA----------------TSTSRRNQV-SISAYD--------------------------------------------------------------------KERPSYNSRNNNNNNNNNNNNNNNNNNNSNNNNSHHHNEDADVDMDSG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [495]
'gi|40555832|gb|AAH64650.1| Hdac1 protein [Danio rerio]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--L-S-SQGTKKKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVAGAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-IMSKVM----------EMYQPSA--------VVLQCG-----ADSLSGDRLGCF--NLTIKGHAKCVEYMKSFNLPLLM-LGGGGYTIRNVARCWTFETAVALD--STIPNELPYNDYFEYFGPDFK-LHISP-SNMTN---------------------------QMQAIPED--A----VQEDSG------------------DEE--DDPDKR-ISIRAHDKRIACDEE--FSDSEDE------GQGGRRN-----------AANYK--------K---------PKRVKTEEE-KDG--E----------------------------------------------------------------------EKKGEPTDVKEEEKAS----------------E---E----KMDTKG------PKE---EL-------KTV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [457]
'gi|15238556|ref|NP 198410.1| histone deacetylase [Arabidopsis thaliana] >gi|21360986|gb|AAM49768.1| HDA7 [Arabidopsis thaliana]'    ------------------------------------------------------------------------------------------------------------------------------------MASLADGGKRRVSY----------------FYE-PMIGDYYYGVNQPTKPQRIRVTHNLILSYNLH--RHMEIN-------------------------HPDLADASDFEKFHSLEYINFLKSVTPETVTDPHPSVSENLKRFNVDV--DWDGPVFHNLFDYCRAYAGGSISAAAKLNRQEADIAINWAGGMHHVKKDKASGFGYVNDVVLAILELLKSFK-------------------------------------------RVLYIEIGFPH--GDEVEEAFKDTDRVMTVSFHKVGD-----TGDISDYGEGKGQYYSLNAPLKDGLDDFSLRGLFIP-VIHRAM----------EIYEPEV--------IVLQCG-----ADSLAGDPFGTF--NLSIKGHGDCLQYVRSFNVPLMI-LGGGGYTLPNVARCWCYETAIAVG--EQLDNDLPGNDYMKYFRPDYK-LHILP-TNRQNLNTRLDIITMRETLLAQLSLVMHAPSVPFQDTPSS--S---QATEAA-----------------------EVDMEKR-NDPRI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [409]
'gi|55586155|ref|XP 513092.1| PREDICTED: similar to Histone deacetylase 1 (HD1) [Pan troglodytes]'                                   ------------------------------------------------------------------------------------------------------------------------------------M---PNCVSEAVAL----------------SSS-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANAEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-VMSKVM----------EMFQPSA--------VVLQCG-----SDSLSGDRLGCF--NLTIKGHAKCVEFVKSFNLPMLM-LGGGGYTIRNVARCWTYETAVALD--TEIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNEYLEKIK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [361]
'gi|47219554|emb|CAG09908.1| unnamed protein product [Tetraodon nigroviridis]'                                    --------------------------------------------------------------------------------------------------------------------------------MA--L-T-SQGTKKKVCY----------------YYD-GDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLY--RKMEIY-------------------------RPHKANGEEMTKYHSDDYIKFLRSIRPDNMSE----YSKQMQRFNVGE--DC--PVFDGLFEFCQLSVGGSVAGAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ-------------------------------------------RVLYIDIDIHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKP-ARARLLLSV-------TEVVPRADNGQGDGDVPAQCGGSPVRSDSLSGDRLGCF--NLTIKGHAKCVEYMKSFNLPLLM-LGGGGYTIRNVARCWTYETAVALD--ASIPNELPYNDYFEYFGPDFK-LHISP-SNMTNQNTNDYLEKIKQRLFENLRMLPHAPGVQMQAIPED--A----VQEDSG------------------DEE-EEDPNKR-ISIRAHDKRIACEEE--FSDSEDE------GEGGRRN-----------SASFK--------K---------AKRAKTEGD-KEGEEK----------------------------------------------------------------------EKK----EVKEEEKVP----------------E---E----E---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [486]
'gi|17561978|ref|NP 506599.1| Histone DeAcetylase family member (hda-1) [Caenorhabditis elegans] >gi|3023926|sp|O17695|HDA1 CAEE'    ---------------------------------------------------------------------------------------------------------------------------------MNSNGPLMEHGKRRVAY----------------YYD-SNIGNYYYGQGHVMKPHRIRMTHHLVLNYGLY--RNLEIF-------------------------RPFPASFEDMTRFHSDEYMTFLKSANPDNLKS----FNKQMLKFNVGE--DC--PLFDGLYEFCQLSSGGSLAAATKLNKQKVDIAINWMGGLHHAKKSEASGFCYTNDIVLGILELLKYHK-------------------------------------------RVLYVDIDVHH--GDGVEEAFYTTDRVMTVSFHKYGDF-FPGTGDLKDIGAGKGKLYSVNVPLRDGITDVSYQSIFKP-IMTKVM----------ERFDPCA--------VVLQCG-----ADSLNGDRLGPF--NLTLKGHGECARFFRSYNVPLMM-VGGGGYTPRNVARCWTYETSIAVD--KEVPNELPYNDYFEYFGPNYR-LHIES-SNAANENSSDMLAKLQTDVIANLEQLTFVPSVQMRPIPED--AL-SALNDDSL------------------IAD-QANPDKR-LPPQITDGMIQDDGD--FYDGERE-------GDDRRN-----------ESDAK--------R---------AAQFESEGG-EKRQKTE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [461]
'gi|39589878|emb|CAE60876.1| Hypothetical protein CBG04588 [Caenorhabditis briggsae]'                                    ---------------------------------------------------------------------------------------------------------------------------------MNSNGPLQEHGKRRVAY----------------YYD-SNIGNYYYGQGHVMKPHRIRMTHHLVLNYGLY--RSMEIF-------------------------RPFPATFDDMTRFHSEEYMLFLKSANPDNLKS----FNKQMLKFNVGE--DC--PLFDGLYEFCQLSSGGSLAAATKLNKQKVDIAINWMGGLHHAKKSEASGFCYTNDIVLGILELLKYHK-------------------------------------------RVLYVDIDVHH--GDGVEEAFYTTDRVMTVSFHKYGDF-FPGTGDLKDIGAGKGKLYSVNVPLRDGITDSSYQSIFKP-IMTKVM----------ERFDPSA--------VVLQCG-----ADSLNGDRLGPF--NLTLKGHGECARFFRSYNVPLMM-VGGGGYTPRNVARCWTYETSIAVD--REVANELPYNDYFEYFGPNYR-LHIEQ-SNANNENNPELLTKLQADVIANLEKLTFVPSVQMRPIEDD--AL-RSMNDSSA------------------LVD-MADPDRR-LPAEVTDQMIQDEGD--FYDGERE-------GDDRRN-----------ESDGK--------R---------AAQLDSEGG-K------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [455]
'gi|67533353|ref|XP 662097.1| hypothetical protein AN4493.2 [Aspergillus nidulans FGSC A4] >gi|8886512|gb|AAF80489.1| histone de'    --------------------------------------------------------------------------------------------------------------------MASGTSGPAGPPLDPIDLNVSGDRSKRVAY----------------FYD-SDVGNYAYVSGHPMKPHRIRMTHSLVMNYSLY--KKMEIY-------------------------RAKPASKFEMTQFHTDEYIDFLSKVTPDNMDA----FAKEQSKYNVGD--DC--PVFDGLFEFCGISAGGSMEGAARLNRNKCDIAVNWAGGLHHAKKSEASGFCYVNDIVLGILELLRFKQ-------------------------------------------RVLYVDIDVHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGELRDIGVGQGKYYAVNFPLRDGIDDVSYKSIFEP-VIKSVM----------EWYRPEA--------VVLQCG-----GDSLSGDRLGCF--NLSMRGHANCVKYVKSFNLPTLI-VGGGGYTMRNVARTWAFETGILVG--DNLGSELPYNDYYEYFAPDYE-LDVRP-SNMDNANTREYLDKIRTQVVENLKRTAFAPSVQMTDVPRE--PLVDGMDDEAEAALDDL------------DED--ENKDKR-FTKRRFDQYVEKPGE--LSDSEDE--DENAANGVTRK-----------PAHLK------------------RRNQANYRL-DLADSGVESGMATPQD----ASSVADEEMDTGTDVKITEAPGPEPDSEAQGTSSAAEPPSRAGNGSVDEPSEMIVDS-KEPPRSVPVSRPVSPKPTDEDTAM-----EDADMPVPEVNQENT-------PEASQATQNKPAEGTPASESAVAKLTSQTKASFESNEGR------------KQ------LEPETVKEAGLAAVTTETKDKTPEAPRAGALPAVTAEQETTKQGEPSAEAQPEAAKE--------------------------------------------------------------------------------------------------------------------------   [687]
'gi|51013077|gb|AAT92832.1| YNL330C [Saccharomyces cerevisiae] >gi|6323999|ref|NP 014069.1| Histone deacetylase; regulates trans'    ---------------------------------------------------------------------------------------------------------------------------MVYEATPFDPITVKPSDKRRVAY----------------FYD-ADVGNYAYGAGHPMKPHRIRMAHSLIMNYGLY--KKMEIY-------------------------RAKPATKQEMCQFHTDEYIDFLSRVTPDNLEM----FKRESVKFNVGD--DC--PVFDGLYEYCSISGGGSMEGAARLNRGKCDVAVNYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHP-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTCSFHKYGEF-FPGTGELRDIGVGAGKNYAVNVPLRDGIDDATYRSVFEP-VIKKIM----------EWYQPSA--------VVLQCG-----GDSLSGDRLGCF--NLSMEGHANCVNYVKSFGIPMMV-VGGGGYTMRNVARTWCFETGLLNN--VVLDKDLPYNEYYEYYGPDYK-LSVRP-SNMFNVNTPEYLDKVMTNIFANLENTKYAPSVQLNHTPRD--A-----EDLGDV-----------------EEDSAEAKDTKGGSQYARDLHVEHDNE--FY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [433]
'gi|50423769|ref|XP 460469.1| hypothetical protein DEHA0F02706g [Debaryomyces hansenii CBS767] >gi|49656138|emb|CAG88776.1| unna'    ----------------------------------------------------------------------------------------------------------------------------MYVQLPFDDLKVDPTQKKRVAY----------------FYD-ADVGNYAYGAGHPMKPHRIRMAHSLIMNYGLY--KKMEIY-------------------------RAKPATKQEMCQFHTDEYIDFLSRVSPDNLDM----FAKEQIKFNVGD--DC--PVFDGLFEYCGISGGGSMEGAARLNRGKCDIAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHP-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTCSFHKYGEF-FPGTGELRDIGVGKGKYHAINVPLRDGIDDATYKSIFEP-VISKVM----------EWYQPSA--------IVLQCG-----GDSLSGDRLGCF--NLSMSGHANCINFVKSFNVPMMV-VGGGGYTMRNVARTWSFEAGLLNN--VVLPSELPYNEYYEYYGPDYK-LDVRP-SNMYNANSPEFLNKILTNILTNLENTKHAPSVQMNYVPND--A-----EDLGDI-----------------DEDTQEAIDTKGGSQQARDEITQPDNE--FYEDDDK---------------------------------------------------------DAGSRDI--------------------------------------------------------------------------------QNFSKSASASESKPAE--LETTAQPETLEEP-EDEKMLTDEELKEINELNSNENNA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [497]
'gi|39580205|emb|CAE71712.1| Hypothetical protein CBG18689 [Caenorhabditis briggsae]'                                    ----------------------------------------------------------------------------------------------------------------------------------------LLHSKSRVSY----------------YYD-GDFGNFYYGQGHPMKPHRVRMTHSLIVNYGLY--RKLTVM-------------------------RPAPASFSEITRYHSDDYVNFLRSVRSDNIQS----LADQMARFSVGE--DC--PVFDGLYEFCQLSCGGSLAAAAKLNRKESDIAINWMGGLHHAKKSEASGFCYSNDIVLAILELLKEHK-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKHGEY-FPGTGDLKDVGAGKGKYYALNVPLRDGVDDFTYERIFRT-VMGEVM----------ARFQPEA--------VVLQCG-----ADSLAGDRLGVF--NLTTYGHGNCVEYMKSFNVPLLL-VGGGGYTIRNVSRCWLYETSLALD--LDVPNELPFNDYFDYFIPDYK-LHIKPLPHLTNYNTQEFIDQTIVSLLDNLKLMTHVPSVQMQPLPTTSDRI-VKTFDENL------------------RRD-HQDDDVR-NSQLDQDVGIEHASE--FYDEQE----------ATRNT---------------------------------HKRQRFESQ-TEASEDAKKTRVDGEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [458]
'gi|46107794|ref|XP 380956.1| hypothetical protein FG00780.1 [Gibberella zeae PH-1] >gi|42547883|gb|EAA70726.1| hypothetical pro'    --------------------------------------------------------------------------------------------------------------------------MGDDIRVELGSVALNASSPKKVAY----------------FYD-SDIGNYAYVTGHPMKPHRIRLAHSLIMQYNLY--QKMEIY-------------------------RAKPATRGEMTQFHTDDYIDFLQKVTPDNMDS----FMREQGKYNVGD--DC--PVFDGLFEFCGISAGGSMEGAARLNRQKCDIAINWAGGLHHAKKCEASGFCYVNDIVLGILELLRFKK-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGELRDTGIGQGKNYAVNFPLRDGITDASYRSIFQP-VIENVM----------KYYQPEA--------VVLQCG-----GDSLSGDRLGCF--NLSMDGHANCVNFVKSFNLPTLV-LGGGGYTMRNVARTWAFETGVLVG--KEMDRTLPYNEYYEYYAPDFE-LNVRS-SNMENSNSREYLEKITSSVIDNLRQTGPAPSVQLQDVPRK--P-FGGMTDEEEAELDDL------------DED--ENKDVR-MTEHRWDKHVEHDNE--FEASDDD--EMARVNGATRQ----------------------------------NGNKRSFTDYRKGEMDVDNPDAPPAKAPNGASNDEAAEEHTGEDGHDVN------------------DDTIDDISAPDQPEKDQPEKATETPTENAKEPELSKVDGDGDVGM-----EDSAVEETTIKKEDVEPEAPEAPTEPSAPTEKSAQDEPTVEAAANDAATTEPIPEPTPAEK------------PA------ESTEKAQSEQPADAMDVDTEKDKPEQPKEKSKSPAN-----------------------------------------------------------------------------------------------------------------------------------------------   [649]
'gi|70989249|ref|XP 749474.1| histone deacetylase RpdA [Aspergillus fumigatus Af293] >gi|66847105|gb|EAL87436.1| histone deacety'    --------------------------------------------------------------------------------------------------------------------M-------AAPPID-LNLNGSGDRSRKVAY----------------FYD-SDVGNYAYVSGHPMKPHRIRMTHSLVMNYGLY--KKMEIY-------------------------RAKPASKYEMTQFHTDEYIDFLSKVTPDNMDQ----FSKEQGKYNVGD--DC--PVFDGLFEFCGISAGGSMEGAARLNRNKCDIAVNWAGGLHHAKKSEASGFCYVNDIVLGILELLRFKQ-------------------------------------------RVLYVDIDVHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGELRDIGVGQGKHYAVNFPLRDGIDDISYKSIFEP-VIRSVM----------EWYRPEA--------VVLQCG-----GDSLSGDRLGCF--NLSMRGHANCVNFVKSFNLPTMI-LGGGGYTMRNVARTWAFETGILLG--ENLGPELPYNDYYEYFAPDYE-LDVRP-SNMDNANTKDYLDKIRAQVVENLKRTAFAPSVQMTDVPRE--PLVEGMDDEADAILDDL------------DED--ENKDKR-FTKRRFDQYIEKPGE--LSDSEDE--EENAANGVLRK-----------PQSLK------------------RRNQINYRN-VDLDSGLDSGVATPQE----ASSVPDDEMDTTADTKTVEAPLPE--SDVPPSPSATGSTSRRDEKAAAEPTEMAVDGPEEASASAAVSHQQSPKPQDEDTTM-----EDAAVSVPETGQSE----KPALPVEGQEEEKKPE--TPALEKAAPEASPAVQASPIPGEKD------------VL------DKPET--NDATEPVEVKAKEKTPEAPTDQQ--AVKTEQGTSEEASENKSSSAPTEVRTNQQPEEPEKGGE-------------------------------------------------------------------------------------------------------------   [688]
'gi|49524335|emb|CAG57932.1| unnamed protein product [Candida glabrata CBS138] >gi|50285207|ref|XP 445032.1| unnamed protein pro'    ---------------------------------------------------------------------------------------------------------------------------MVYESKPFDPITVKPNDKKRVAY----------------FYD-ADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLY--KKMEIY-------------------------RAKPATKQEMCQFHTDEYIDFLSRVTPDNLEM----FKKESVKFNVGD--DC--PVFDGLYEYCSISGGGSMEGAARLNRGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHP-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTCSFHKYGEF-FPGTGELRDIGVGKGKYYAVNVPLRDGIDDATYRSVFEP-VIGKIM----------EWYQPSA--------VVLQCG-----GDSLSGDRLGCF--NLSMEGHANCVNYVKSFGIPMMV-VGGGGYTMRNVARTWCFETGLLNN--VVLDQELPYNEYYEYYGPDYK-LDVRP-SNMYNVNTPEYLDKILLGIFQNLENTKYAPSVQLNNVPND--P-----EDKGDE-----------------EEDTNEAKDTKGGSQYARDNMVQNDTE--FY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [433]
'gi|66735114|gb|AAY53803.1| histone deacetylase 3 [Toxoplasma gondii]'                                    --------------------------------------------------------------------------------------------------------------------------------------MALSALRKRVAY----------------FYD-PDIGSYYYGPGHPMKPQRIRMAHALVLSYDLY--KHMEVY-------------------------RPHKSIEPELCLFHSSDYISFLSSVSPENYKE----FSLQLKNFNVGEATDC--PVFDGLFTFQQACAGASIDAAKKLNHHQADICVNWSGGLHHAKRSEASGFCYINDIVLGILELLKYHA-------------------------------------------RVMYIDIDIHH--GDGVEEAFYVSHRVMTVSFHKFGDF-FPGTGDVTDVGASQGKYYAVNVPLNDGMDDDSFVALFKP-VITKCV----------DVYRPGA--------IVLQCG-----ADSLTGDRLGKF--NLTIKGHAACVAFVKSLDIPLLV-LGGGGYTIRNVARCWAYETGVVLDRHREMSPHVPLNDYYDYYAPDFQ-LHLTP-SSIPNSNSPEHLEKIKTRVLSNLSYLEHAPGVQFAYVPPD--F----FGEDND------------------DED-----------------------E--FMQNQVD------NEGGGRAAGATAH--TAANAPYR------------------IRRKDYAND-FEDMADRDQKVPI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [451]
'gi|14333978|gb|AAK58884.1| reduced potassium dependency 3 Rpd3p [Kluyveromyces lactis]'                                    ---------------------------------------------------------------------------------------------------------------------------MVYEAKPFDPITVKANEKKRVAY----------------FYD-ADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLY--KKMEIY-------------------------RAKPATKQEMCQFHTDEYIDFLSRVTPDNLDM----FQKESVKFNVGD--DC--PVFDGLYEYCSISGGGSMEGAARLNRGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHP-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTCSFHKYGEF-FPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEP-VIGKIM----------EWYQPSA--------VVLQCG-----GDSLSGDRLGCF--NLSMKGHANCVNYMKSFGVPLMI-VGGGGYTMRNVARTWAFETGILNN--VILDEELPYNDYYEYYGPDYK-LDVRP-SNMYNVNTPEYLDKVLLNIFSNLKHTKYAPSVQLNHVPRD--A-----EDKGDA-----------------EEDTAAAKDTRGGSQYARDITIENATE--F----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [432]
'gi|50308073|ref|XP 454037.1| unnamed protein product [Kluyveromyces lactis] >gi|49643172|emb|CAG99124.1| unnamed protein produc'    ---------------------------------------------------------------------------------------------------------------------------MVYEAKPFDPITVKANEKKRVAY----------------FYD-ADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLY--KKMEIY-------------------------RAKPATKQEMCQFHTDEYIDFLSRVTPDNLDM----FQKESVKFNVGD--DC--PVFDGLYEYCSISGGGSMEGAARLNRGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHP-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTCSFHKYGEF-FPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEP-VIGKIM----------EWYQPSA--------VVLQCG-----GDSLSGDRLGCF--NLSMKGHANCVNYMKSFGVPLMI-VGGGGYTMRNVARTWAFETGILNN--VILDEELPYNDYYEYYGPDYK-LDVRP-SNMYNVNTPEYLDKVLLNIFSNLEHTKYAPSVQLNHVPRD--A-----EDKGDA-----------------EEDTAAAKDTRGGSQYARDITIENATE--F----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [432]
'gi|3879019|emb|CAB03240.1| Hypothetical protein R06C1.1 [Caenorhabditis elegans] >gi|3878853|emb|CAB03224.1| Hypothetical prote'    --------------------------------------------------------------------------------------------------------------------------------------MSLQHSKSRVSY----------------YYD-GDFGNFYYGQGHPMKPHRVRMTHSLIVNYGLY--RKLNVM-------------------------RPARASFSEITRYHSDDYINFLRNVKSDNMST----FTDQMARFSVGE--DC--PVFDGMYEFCQLSCGGSLAAAARLNRQESEIAINWMGGLHHAKKSEASGFCYSNDIVLAILELLKHHK-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKHGEY-FPGTGDLKDVGAGSGKYYALNVPLRDGVDDVTYERIFRT-IMGEVM----------ARFQPEA--------VVLQCG-----ADSLAGDRLGVF--NLTTYGHGKCVEYMKSFNVPLLL-VGGGGYTIRNVSRCWLYETAIALN--QEVSDDLPLHDYFDYFIPDYK-LHIKPLAALSNFNTPEFIDQTIVALLENLKQLPHVPSVQMQSISTSCDSI-VKTFDEKL------------------IRD-HQNDDVR-VTQFEEDVQVEDSAE--FYDGQEP---------ETKNI---------------------------------QSMKRHASPICAAQEEMKKNRIDGGENVA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [465]
'gi|68472201|ref|XP 719896.1| putative Sin3.Rpd3 histone deacetylase complex component Rpd3p [Candida albicans SC5314] >gi|68472'    ----------------------------------------------------------------------------------------------------------------------------MYTELPFDELKVDPNQKKRIAY----------------FYD-ADIGNYAYGAGHPMKPHRIRMAHSLIMNYGLY--KKMEIY-------------------------RAKPATKQEMCQFHTDEYIDFISRVNPDNLDL----FTKEQIKFNVGD--DC--PVFDGLFEYCGISGGGSMEGAARLNRGKCDIAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHP-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTCSFHKYGEF-FPGTGELRDIGVGKGKYHSVNVPLRDGIDDATYKSVFEP-VISKII----------EWYQPSA--------IVLQCG-----GDSLSGDRLGCF--NLSMNGHANCINYVKSFNIPMMV-VGGGGYTMRNVARTWAYESGLLNN--VKLPDELPYNEYYEYYGPDYK-LDVRS-SNMFNQNSPEFLDKILTNIIANLENTKHAPSVQMNEVPND--P-----EDLGDV-----------------EEDTAMAIDTKGGSEMSRDAQIQPDNE--FYEDDEK---------------------------------------------------------DKGEKAIIDNKHEDQDSMQVDKSEEPVVEQKDKPQDENNVTGDNIEEDQPQEVNPIEEQPSVEKSVVVVEDKLEEVKPVEQKVEEPKEVVDKPEDKHEDKPAETLTETTTESKPEDQPMEDAAKLTEEELKEIEELNKSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [577]
'gi|44986425|gb|AAS54885.1| AGR395Wp [Ashbya gossypii ATCC 10895] >gi|45201491|ref|NP 987061.1| AGR395Wp [Eremothecium gossypii]'    ---------------------------------------------------------------------------------------------------------------------------MVFVQKPFDELTVNSSQKKRVAY----------------FYD-ADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLY--KKMEIY-------------------------RAKPATKQEMCQFHTDEYIDFLSRVTPDNLDM----FQKESVKFNVGD--DC--PVFDGLYEYCSISGGGSMEGAARLNRGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHP-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTCSFHKYGEF-FPGTGELRDTGVGKGKYYSVNVPLRDGIDDATYKSVFEP-VIGKIM----------EWYQPSA--------VVLQCG-----GDSLSGDRLGCF--NLSMRGHANCVNYVKSFGIPMMV-VGGGGYTMRNVARTWAFETGLLNN--VLLDEELPYNDYYEYYGPDYK-LDVRP-SNMFNVNSPEYLDKVLASIFSNLEHTKYAPSVQLNHVPRD--P-----EDEGDV-----------------EEDTSEAKDTRGGSQFARDQIVEKENE--FY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [433]
'gi|88185568|gb|EAQ93036.1| hypothetical protein CHGG 01271 [Chaetomium globosum CBS 148.51]'                                    ---------------------------------------------------------------------------------------------------------------------MPKTTDPSGVERSRPLYEIVNNDKKRVAY----------------FYD-SDIGNYAYVTGHPMKPHRIRLAHSLVMNYDVY--KFLEIYVSLLLCGGTCLLRTLADGVCLASKQRAKPAVTSEMTQFHTDEYIEFLQKVTPDNMDG----FMREQGKYNVGD--DC--PVFDGLFEFCGISAGGSMEGAARLNREKCDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLRFKK-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGELRDIGIGNGKHYAVNFPLRDGIDDTTYDTIFEP-VIEAVM----------KYFQPEA--------VVLQCG-----GDSLSGDRLGCF--NLSMRGHANCVNFVRSFNLPTLV-LGGGGYTMRNVARTWAYETGRLVG--VEMDSVLPYNEYYTYYGPDYE-LDVRS-SNMENANSYEYLEKIKIAVIENLKRTAHAPSVQMQDVPRQ--SM--GMSDDQEAELD--------------DRDEEENPDAR-LTQRQWEKRVERQDE--YEESDDE--DMARANGVYKP----------------------------------NGRSRQETNFRPTNKD---------------------DDTMEVDSRAATPPEPAAEATVDNDDPMMEEELAEVLAEVAQMEAQDAAADEKTAAEQATETDKPKVDGDGDVDMTEATSADTKEPEATIKREEVEGISATEAEPTKSPVPENTKVADDGEASTTKERGSASPEIAEPDAK------------PA------EEGPSAEKSDDAAIADKKAGDDEAMA---------------------------------------------------------------------------------------------------------------------------------------------------------   [670]
gnl|CMER|CMJ129C_histone_deacetylase                                    ----------------------------------------------------------------------------------------------------------------------MKAEAGTSESRV----GTLEAFPSRVAY----------------FYD-HDVGNYYYALGHPMKPHRMRMVHELLIAYGVH--EKLQVL-------------------------QPPRATERDLTRFHSDEYIEFLRRITPETAQK----QLDQLQRFGLFE--DS--PCFDDIYRFCQISAGGSLAGAARLNRGFCDVAINWSGGLHHAKKSEASGFCYVNDCVLAILELLKHHA-------------------------------------------RVLYCDIDVHH--GDGVEEAFYTTNRVMTCSFHKFGNF-FPGTGDVRDIGYGPGRHYALNFPLQDGIDDVCYREIFAP-IMSRVM----------EWYQPTA--------VVLQCG-----ADSLSGDRLGCF--NLSLDGHAQCVRFFQRYGVQLML-LGGGGYTIRNVARCWAYETALAAG--VVLDDMIPYNPYYEYYGPDFR-LRIRP-SNMENLNTPSYLHRMMVQLLESLRSLPHTPSVPFHSVPAD--V----ISDPLL------------------RKF------SA-PVPLSDDEHSVCSSD--WDD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [428]
'gi|47682973|gb|AAH70873.1| LOC432017 protein [Xenopus laevis]'                                    --------------------------------------------------------------------------------------------------------------------------SAGASTCRSIRPVCGSEMAKTVAY----------------FYD-PDVGNFHYGTGHPMKPHRLSLTHSLVLHYGLY--KKMIVF-------------------------KPYQASQHDMCRFHSEDYIDFLQRVSPNNMQG----FTKSLNAFNVGD--DC--PVFPGLFEFCSRYTGASLQGATLLNNKNCDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHP-------------------------------------------RVLYIDIDIHH--GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYRHLFQP-VIKQVI----------DFYQPTC--------IVLQCG-----ADSLGCDRLGCF--NLSIRGHGECVQYVKSFNIPLLV-LGGGGYTVRNVARCWTYETSLLVD--ETISEELPYSEYFEYFAPDFT-LHPDVSTRIENQNSRQYLDQIRQTVFESLKMLNHAPSVQIHDVPSD--I----LNYE--------------------RTD-EPDPEER-GGEDNYSRP-EASNE--FYDGDHD---------------------------------------------------------NDKESDVEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [445]
'gi|45382059|ref|NP 990078.1| histone deacetylase 3 [Gallus gallus] >gi|2791688|gb|AAB96925.1| histone deacetylase-3; HD-3 [Gall'    -------------------------------------------------------------------------------------------------------------------------------------------MAKTVAY----------------FYD-PDVGNFHYGAGHPMKPHRLALTHSLVLHYGLY--KKMIVF-------------------------KPYQASQHDMCRFHSEDYIDFLQRVSPNNMQG----FTKSLNAFNVGD--DC--PVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHP-------------------------------------------RVLYIDIDIHH--GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYALNVPLRDGIDDQSYKHLFQP-VINQVV----------DYYQPTC--------IVLQCG-----ADSLGRDRLGCF--NLSIRGHGECVEYVKSFNIPLLV-LGGGGYTVRNVARCWTYETSLLVD--EAISEELPYSEYFEYFAPDFT-LHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPSD--L----LSYD--------------------RTD-EPDPEER-GSEENYSRP-EAANE--FYDGDHD---------------------------------------------------------NDKESDVEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [428]
'gi|62859851|ref|NP 001016883.1| histone deacetylase 3 [Xenopus tropicalis] >gi|89272754|emb|CAJ81493.1| histone deacetylase 3 ['    -------------------------------------------------------------------------------------------------------------------------------------------MAKTVAY----------------FYD-PDVGNFHYGTGHPMKPHRLSLTHSLVLHYGLY--KKMIVF-------------------------KPYQASQHDMCRFHSEDYIDFLQRVSPNNMQG----FTKSLNAFNVGD--DC--PVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHP-------------------------------------------RVLYVDIDIHH--GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYRHLFQP-VIKQVI----------DFYQPTC--------IVLQCG-----ADSLGCDRLGCF--NLSIRGHGECVQYVKSFNIPLLV-LGGGGYTVRNVARCWTYETSLLVD--ETISEELPYSEYFEYFAPDFT-LHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPSD--I----LSYE--------------------RTD-EPDPEER-GSEDNYSRP-EASNE--FYDGDHD---------------------------------------------------------NDKESDVEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [428]
'gi|71029932|ref|XP 764608.1| histone deacetylase [Theileria parva strain Muguga] >gi|68351564|gb|EAN32325.1| histone deacetylas'    -------------------------------------------------------------------------------------------------------------------------------------------MDKRVSY----------------FYD-PDVGSFYYGPGHPMKPQRIRMAHALVLSYDLY--RHMEIF-------------------------RPHKAVEPELLSFHDSEYVHFLSGVSPENYRD----FTYQLKRFNVGEATDC--PVFDGLYVFQQSCSGASIDAAHRLNNQQADICVNWSGGLHHAKRSEASGFCYLNDIVLGILELLKYHA-------------------------------------------RVMYIDIDVHH--GDGVEEAFYVTHRVMTISFHKFGNF-FPGTGDVTDVGVSSGKYYSVNVPLNDGIDDESFVDLFKV-VVGKCV----------EVYCPGA--------IVLQCG-----ADSLTGDRLGRF--NLTIKGHAACVQYVRSLNIPLLV-LGGGGYTIRNVARCWAYETGVILNKHTDMSNQISLNDYYDYYAPDFQ-LHLTP-SQMTNYNTKEHLDKIKVKILDNLRYVEKSPGVQFAHVPPD--F----LTRDD-------------------DVD-----------------------D--DLQKQVF------DEGGGRTSLSTRKRISLITSSHK------------------LRRRDYKGE-LYDLPDRDDQIPI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [447]
'gi|57227833|gb|AAW44291.1| conserved hypothetical protein [Cryptococcus neoformans var. neoformans JEC21] >gi|58268884|ref|XP 5'    ---------------------------------------------------------------------------------------------------------------------------------MGSMEPILGESKRRVCY----------------FFD-SDIGNYHYGPGHPMKPTRIRMCHSLVMNYGLY--KKMEIF-------------------------RAKPATKREMSQFHTDEYVDFLYRINPDNAAQ----FAKEQVKYNVGD--DC--PIFDGLFEYCSISAGGSMEGAARLSRDKCDIAVNWAGGLHHAKKAEASGFCYVNDIVLGILELLRYHQ-------------------------------------------RVLYIDIDVHH--GDGVEEAFYTTDRVMTCSFHKYGEF-FPGTGEVRDNGIGKGKGYAINVPLRDGISDDNYKSIFQP-VIKRVI----------EWYQPGA--------VVLQCG-----SDSLSGDRLGSF--NLSMKGHAACVQFVKSFNLPLLL-LGGGGYTVKSVSRTWAYETGLAAG--MELGRDLPNNEYWEYYGPDYE-LDVRS-SNMTDQNTPEYLQKVTEAVFEVLRDKNAAPSVPLQSIPKM-------MHDDEDEDE---------------GED-NEDRDVR-RPARLWAREKQHETS--LSDSEDE------GTGGRRH-----------RRSYKE-----------------SAQKNTMVE-DQCNFRVNAGFT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [466]
;
END;


BEGIN CODONS;
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END;


BEGIN ASSUMPTIONS;
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END;


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