#NEXUS 
[MacClade 4.08 registered to M. Hasebe, NIBB]


BEGIN DATA;
	DIMENSIONS  NTAX=189 NCHAR=1234;
	FORMAT DATATYPE=PROTEIN  SYMBOLS = " 1 2 3 4"  MISSING=? GAP=- ;
MATRIX
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'gi|15240691|ref|NP 196875.1| SMT1 (STEROL METHYLTRANSFERASE 1) [Arabidopsis thaliana] >gi|11066105|gb|AAG28462.1| sterol methyl'     ----------------------------------------------------------------------------------------------------------------------------------------MDLASN---------------------LGG-KIDKSDVLT-------AV-EKYEQY-------HV--------FHGG-------------------------------------------------------------------------NEE----ERK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANYTDMVNKY------YDLA----T--SF-YEYGW-----GE-----------------SFHFAQ------------------------RW-K------GES-------------LRESIKRHEHFLALQLG-IQ-----------------PGQK-----------VLDVGCGIGGPLREIARFS-NSV--VTGLNN-NEYQITRGKELNRLA--G-------------------------VD-KT----------------CNFVKADF-MKMP--FP--ENSFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDA----------------FD---PDNAEHQKIKGEIEI--GDGLP----------DIRLTTKCLEALKQAGF---EVI-WEKDLAK------DS-P-VPW--YLPLDKNHFS----------LSSFRLTAVGRFITKNMV------------------------------------KILEYIRLAPQGSQR-VSN----------------FLEQ-----------------------------AAEGLVDG-------GRREIF---------------------------TPMYFFLARKPE------------------------------------------------------------------------------   [336]
'gi|21434843|gb|AAM53553.1| cephalopod [Arabidopsis thaliana]'                                    ----------------------------------------------------------------------------------------------------------------------------------------MDLASN---------------------LGG-KIDKSDVLT-------AV-EKYEQY-------HV--------FHGG-------------------------------------------------------------------------NEE----ERK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANYTDMVNKY------YDLA----T--SF-YEYGW-----GE-----------------SFHFAQ------------------------RW-K------GES-------------LRESIKRHEHFLALQLG-IQ-----------------PGQK-----------VLDVGCGIGGPLREIARFS-NSA--VTGLNN-NEYQITRGKELNRLA--G-------------------------VD-KT----------------CNFVKADF-MKMP--FP--ENNFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQCFAAYEWCMTDA----------------FD---PDNAEHQKIKGEIEI--GDGLP----------DIRLTTKCLEALKQAGF---EVI-WEKDLAK------DS-P-VPW--YLPLDKNHFS----------LSSFRLTAVGRFITKNMV------------------------------------KILEYIRLAPQGSQR-VSN----------------FLEQ-----------------------------AAEGLVDG-------GRREIF---------------------------TPMYFFLARKPE------------------------------------------------------------------------------   [336]
'gi|1399380|gb|AAB04057.1| S-adenosyl-L-methionine:delta24-sterol-C-methyltransferase'                                    ------------------------------------------------------------------------------------M------------------------QKKKKNRNEVVLCSAEGTGGCSRLAA-MDLASN---------------------LGG-KIDKAEVLS-------AV-QKYEKY-------HV--------CYGG-------------------------------------------------------------------------QEE----ERK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANYTDMVNKY------YDLV----T--SF-YEFGW-----GE-----------------SFHFAP------------------------RW-K------GES-------------LRESIKRHEHFLPLQLG-LK-----------------PGQK-----------VLDVGCGIGGPLREISRFS-STS--ITGLNN-NEYQITRGKELNRIA--G-------------------------VD-KT----------------CNFVKADF-MKMP--FP--DNSFDAVYAIEATCHAPDAYGCYKEIFRVLKPGQYFAAYEWCMTDS----------------FD---PQNPEHQKIKAEIEI--GDGLP----------DIRLTAKCLEALKQAGF---EVI-WEKDLAV------DS-P-LPW--YLPLDKSHFS----------LSSFRLTAVGRLFTKNMV------------------------------------KVLEYVGLAPKGSLR-VQD----------------FLEK-----------------------------AAEGLVEG-------GKREIF---------------------------TPMYFFLARKPDLDRN--------------------------------------------------------------------------   [367]
'gi|73761691|gb|AAZ83345.1| 24-sterol C-methyltransferase [Gossypium hirsutum]'                                    ------------------------------------------------------------------------------------M---------------------------------------------SKAGA-LDLASG---------------------LGG-KIEKAEVLS-------AV-EQYERY-------HV--------FYGG-------------------------------------------------------------------------EEE----ERK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANYTDMVNKY------YDLV----T--SF-YEFGW-----GE-----------------SFHFAP------------------------RW-N------GES-------------LKESIKRHEHFLALQLG-LK-----------------PGHK-----------VLDVGCGIGGPLREIARFS-STS--VTGINN-NEYQITRGKELNRIA--G-------------------------VE-KT----------------CNFVKADF-MKMP--FP--DSAFDAVYAIEATCHAPDAYGCYKEIYRVLKPGQYFAAYEWCMTDS----------------FD---PNNSEHQKIKAEIEI--GDGLP----------DIRLTGQCLEALKEAGF---EII-WEKDLAV------GS-P-LPW--YLPLDTSHFS----------LSSFRLTSVGRFITRNMV------------------------------------KALEFVGLAPKGSQR-VQD----------------FLEK-----------------------------AAEGLVEG-------GRKEIF---------------------------TPMYFFLARKPLSESQ--------------------------------------------------------------------------   [346]
'gi|2246458|gb|AAB62812.1| S-adenosyl-methionine-sterol-C- methyltransferase [Ricinus communis]'                                    ------------------------------------------------------------------------------------M---------------------------------------------SKAGA-LDLASG---------------------VGG-KIDKNEVLS-------AV-EKYEKY-------HV--------YYGG-------------------------------------------------------------------------AEE----ERK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANYTDMVNKY------YDLV----T--SF-YEFGW-----GE-----------------SFHFAH------------------------RF-K------GES-------------LRESIKRHEHFLALQLG-LK-----------------PEQK-----------VLDVGCGIGGPLREISRFS-LTS--VTGLNN-NEYQITRGKVLNRIA--G-------------------------VD-KT----------------CDFVKADF-MKMP--FP--ANSFDAVYAIEATCHAPDAYGCYSEIYRVLKPGQFFAAYEWCMTDS----------------FD---PNNQEHQKIKAEIEI--GDGLP----------DIRLTGQCIEALKKAGF---DVI-WSGDLTA------SS-P-VPW--YLPLDKNQYS----------LTGFRLTAIGRFFTRNMI------------------------------------KALEFAGLAPKGSQR-VQD----------------FLEK-----------------------------AAEGLVEG-------GRKEIF---------------------------TPMFFFLAQKPHSENQ--------------------------------------------------------------------------   [346]
'gi|1899060|gb|AAB70886.1| endosperm C-24 sterol methyltransferase [Zea mays]'                                    ------------------------------------------------------------------------------------M---------------------------------------------SKSGA-LDLASG---------------------LGG-KINKVEVKS-------AV-DEYEKY-------HG--------YYGG-------------------------------------------------------------------------KEE----ARK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNYTDMVNKY------YDLA----T--SF-YEYGW-----GE-----------------SFHFAH------------------------RW-N------GES-------------LRESIKRHEHFLALQLG-LK-----------------PGMK-----------VLDVGCGIGGPLREIARFS-STS--VTGLNN-NEYQITRGKELNRLA--G-------------------------IS-GT----------------CDFVKADF-MKMP--FD--DNTFDAVYAIEATCHAPDPVGCYKEIYRVLKPGQCFAVYEWCITDH----------------YD---PNNATHKRIKDEIEL--GNGLP----------DIRSTRQCLQAVKDAGF---EVV-WDKDLAE------DS-P-LPW--YLPLDPSRFS----------LSSFRLTSVGRMITRTMV------------------------------------KALEYVGLAPQGSER-VSN----------------FLEK-----------------------------AAEGLVEG-------GKKEIF---------------------------TPMYFFLVRKPLLE----------------------------------------------------------------------------   [344]
'gi|3560474|gb|AAC34951.1| S-adenosyl-methionine-sterol-C- methyltransferase [Nicotiana tabacum]'                                    ------------------------------------------------------------------------------------M---------------------------------------------SKQGA-FDLASG---------------------VGG-KINKEEVLS-------AV-DKYEKY-------HG--------YYGG-------------------------------------------------------------------------EEE----ERK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NNYTDMVNKY------YDLC----T--SF-YEYGW-----GE-----------------SFHFAP------------------------RW-K------GES-------------LQESIKRHEHFLALQLG-LK-----------------PGQK-----------VLDVGCGIGGPLREIARFS-STS--VTGLNN-NEYQISRGQVLNRKV--G-------------------------LD-QT----------------CNFVKGDF-MKMP--FP--DNSFDAVYAIEATCHAPDPLGCYKEIYRVLKPGQCFAVYEWCMTDS----------------YN---PNNEEHNRIKAEIEL--GNGLP----------EVRLTTQCLEAAKQAGF---EVV-WDKDLAD------DS-P-VPW--YLPLDTSHFS----------LSSFRLTAVGRLFTRNLV------------------------------------SALEYVGLAPKGSQR-VQA----------------FLEK-----------------------------AAEGLVGG-------AKKGIF---------------------------TPMYFFVVRKPISDSQ--------------------------------------------------------------------------   [346]
'gi|50935101|ref|XP 477078.1| cycloartenol-C24-methyltransferase [Oryza sativa (japonica cultivar-group)] >gi|34393309|dbj|BAC83'     ------------------------------------------------------------------------------------M---------------------------------------------SRSGA-MDLASG---------------------LGG-KITKDEVKS-------AV-DEYEKY-------HG--------YYGG-------------------------------------------------------------------------KEE----ARK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNYTDMVNKY------YDLA----T--SF-YEYGW-----GE-----------------SFHFAH------------------------RW-N------GES-------------LRESIKRHEHFLALQLG-VK-----------------PGMK-----------VLDVGCGIGGPLREIAKFS-LAS--VTGLNN-NEYQITRGKELNRVA--G-------------------------VS-GT----------------CDFVKADF-MKMP--FS--DNTFDAVYAIEATCHAPDPVGCYKEIYRVLKPGQCFAVYEWCITDH----------------YE---PNNATHKRIKDEIEL--GNGLP----------DIRSTQQCLQAAKDAGF---EVI-WDKDLAE------DS-P-VPW--YLPLDPSRFS----------LSSFRLTTVGRAITRTMV------------------------------------KALEYVGLAPQGSER-VSN----------------FLEK-----------------------------AAEGLVEG-------GKKEIF---------------------------TPMYFFLVRKPISE----------------------------------------------------------------------------   [344]
'gi|2909846|gb|AAC04265.1| (S)-adenosyl-L-methionine:delta 24-sterol methyltransferase [Zea mays]'                                    ------------------------------------------------------------------------------------M---------------------------------------------SKSGA-LDLASG---------------------LGG-KINKVEVKS-------AV-DEYEKY-------HG--------YYGG-------------------------------------------------------------------------KEE----ARK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNYTDMVNKY------YDLA----T--SF-YEYGW-----GE-----------------SFHFAH------------------------RW-N------GES-------------LRESIKRHEHFLALQLG-LK-----------------PGMK-----------VLDVGCGIGGPLREIARFS-STS--VTGLNN-NEYQITRGKELNRLA--G-------------------------IS-GT----------------CDFVKADF-MKMP--FD--DNTFDAVYAIEATCHAPDPVGCYKEIYRVLKPGQCFAVYEWCVTDH----------------YD---PNNATHKRIKDEIEL--GNGLP----------DIRSTRQCLRAVKDAGF---EVV-WDKDLAE------DS-P-LPW--YLPLDPSRFS----------LSSFRLTSVGRMITRTMV------------------------------------KALEYVGLAPQGSER-VSS----------------FLEK-----------------------------AAEGLVEG-------GKKEIF---------------------------TPMYFFFVRKPLLE----------------------------------------------------------------------------   [344]
'gi|3560531|gb|AAC34988.1| cycloartenol-C24-methyltransferase [Oryza sativa subsp. japonica]'                                    ------------------------------------------------------------------------------------M---------------------------------------------SRSGA-MDLASG---------------------LGG-KITKDEVKS-------AV-DEYEKY-------HG--------YYGG-------------------------------------------------------------------------KEE----ARK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNYTDMVNKY------YDLA----T--SF-YEYGW-----GE-----------------SFHFAH------------------------RW-N------GES-------------LRESIKRHEHFLALQLG-VK-----------------PGMK-----------VLDVGCGIGGPLREIAKFS-LAS--VTGLNN-NEYQITRGKELNRVA--G-------------------------VS-GT----------------CDFVKADF-MKMP--FS--DNTFDAVYAIEATCHAPDPVGCYKEIYRVLKPGQCFAVYEWCITDH----------------YE---PNNATHKRIKDEIEL--GNGLP----------DIRSTQQCLQAAKDAGF---EVI-WDKDLAE------DS-P-VPW--YLPLDPSRFS----------LSSFRLTTVGRAITRTMV-------------------------------KALEYKALEYVGLAPQGSER-VSN----------------FLEK-----------------------------AAEGLVEG-------GKKEIF---------------------------TPMYFFLVRKPISE----------------------------------------------------------------------------   [349]
'gi|3603295|gb|AAC35787.1| S-adenosyl-methionine cycloartenol-C24-methyltransferase [Nicotiana tabacum]'                              ------------------------------------------------------------------------------------M---------------------------------------------SKQGALFDLASG---------------------VGG-KINKEKVLS-------AV-DKYEKY-------HG--------YYGG-------------------------------------------------------------------------EEE----ERK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NNYSDMVNKY------YDLS----T--SF-YEYGW-----GE-----------------SFHFAP------------------------RW-K------GES-------------LLESIKRNEHFLALQLG-LK-----------------PGQK-----------VLDVGCGIGGPLREIARFS-STS--ITGLNN-NEYQITRGQELNNKI--G-----------------------LTLN-QT----------------CNFVKGDF-MKMS--FP--DNSFDAVYAIAATCHAPDVVGCYKEIYRVLKPGQCFAVYEWCMTDS----------------YD---PNNEEHEKIKSEIEL--GNGLP----------EVRLTSQCLEAAKQAGF---EVV-WDKDLAE------DS-P-VPW--YLPLDTSHFS----------FSSFPLTALGRLLTRNLV------------------------------------SALEFVGLAPKGSQR-VQG----------------FLEK-----------------------------AAQGLVGG-------AKKGIF---------------------------TPLYFFLVRKPISDLK--------------------------------------------------------------------------   [349]
'gi|1872473|gb|AAB49338.1| delta-24-sterol methyltransferase [Triticum aestivum]'                                    ------------------------------------------------------------------------------------M---------------------------------------FVFCLCTRCRI-CRVSSFPVLLLFMFIHLSYFFLVLLLILG---------QF-------FF-TRYEKY-------HG--------YYGG-------------------------------------------------------------------------KEE----SRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNYTDMVNKY------YDLA----T--SF-YEYGW-----GE-----------------SFHFAH------------------------RW-N------GES-------------LRESIKRHEHFLALQLE-LK-----------------PGMK-----------VLDVGCGIGGPLREIARFS-STS--VTGLNN-NDYQITRGKALNRSV--G-------------------------LG-AT----------------CDFVKADF-MKMP--FS--DNTFDAVYAIEATCHAPDPVGCYKEIYRVLKPGQCFAVYEWCITDH----------------YD---PNNATHKRIKDEIEL--GNGLP----------DIRSTRQCLQAVKDAGF---EVI-WDKDLAE------DS-P-LPW--YLPLDPSRFS----------LSSFRLTTVGRIITRNMV------------------------------------KVLEYVGLAPEGSQR-VSS----------------FLEK-----------------------------AAEGLVEG-------GKKEIF---------------------------TPMYFFVVRKPLSE----------------------------------------------------------------------------   [363]
'gi|1706965|gb|AAB37769.1| delta-24-sterol methyltransferase [Triticum aestivum]'                                    ------------------------------------------------------------------------------------M---------------------------------------FVFCLCTRCRI-CRVSSFPVLLLFMFIHLSYFFLVLLLILG---------QF-------FF-TRYEKY-------HG--------YYGG-------------------------------------------------------------------------KEE----SRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNYTDMVNKY------YDLA----T--SF-YEYGW-----GE-----------------SFHFAH------------------------RW-N------GES-------------LRESIKRHEHFLALQLE-LK-----------------PGMK-----------VLDVGCGIGGPLREIARFS-STS--VTGLNN-NDYQITRGKALNRSV--G-------------------------LG-AT----------------CDFVKADF-MKMP--FS--DNTFDAVYAIEATCHAPDPVGCYKEIYRVLKPGQCFAVYEWCITDH----------------YD---PNNATHKRIKDEIEL--GNGLP----------DIRSTRQCLQAVKDAGF---EVI-WDKDLAE------DS-P-LPW--YLPLDPSRFS----------LSSFRLTTVGRIITRNMV------------------------------------KVLEYVGLAPEGSQR-VSS----------------FLEK-----------------------------AAEGLVEG-------GKKEIF---------------------------TPVYFFVVRKPLSE----------------------------------------------------------------------------   [363]
lcl|Smo_SMT1_13_2_unnamed_protein_product                                    ------------------------------------------------------------------------------------M---------------------------------------------AKAGA-MDLASG---------------------LGG-NLSRRDLAS-------SV-DQYEKY-------HS--------FYGG-------------------------------------------------------------------------EED----KRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FNYTDMVNKY------YDLA----T--SF-YEYGW-----GQ-----------------SFHFAN------------------------RF-Q------DET-------------LQESIKRHEHFLALHLG-LK-----------------PEMKVIYLSIRKLDEVLDVGCGIGGPLREIARFS-GAS--ITGLNN-NGYQISRGTELNKKY--G-------------------------LD-KT----------------CDFVKADF-MKMP--LA--DNTYDAVYAIEATCHAPDAVGCYKEIWRVLKPGQCFAAYEWCMTDA----------------YD---PHNEHHNKMKAEIEL--GNGLP----------DIRTTRQCLEAAKEAGF---EIL-VEDDLAK------TS-P-LPW--YLPIDPGRFS----------LSSFRLTRLGRFFTRNLV------------------------------------WVLESIKVAPEGSGR-VSQ----------------FLEK-----------------------------GADGLVAG-------GKKEIF---------------------------TPMYFFLARKPL------------------------------------------------------------------------------   [353]
'gi|50919277|ref|XP 470035.1| putative endosperm C-24 sterol methyltransferase [Oryza sativa (japonica cultivar-group)] >gi|3010'     ------------------------------------------------------------------------------------M------------------------------------------------------ACH--------------------------------IS-------AR-SRYENY-------HE--------IYGG-------------------------------------------------------------------------EVE----SRT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNYADLANKY------YDLV----T--SF-YEYGW-----GE-----------------SFHFGS------------------------RW-Q------GET-------------LRESLKRHEHFLALQLG-LK-----------------KGMK-----------VLDVGCGIGGPLREIARFS-SAS--VTGLNN-NAYQISRGKELNFSV--G-------------------------LS-ET----------------CNFVKADF-MNMP--IP--DATFDAAYAIEATCHAPDAVGVYREICRVLKPGQLFALDEWCMTDK----------------YD---PGNSRHRSIKAEIEL--GNGLP----------DIRTTKQCIQALKDAGF---EVV-SVKDLAE------DS-P-LPW--YLPLDSSQFS----------LNGFRLTRVGRFITHMLV------------------------------------KTLECLHVAPQGSLR-VSS----------------FLET-----------------------------AAEGLVKG-------AKEGIF---------------------------TPIFFVLARKPLDKQPEI------------------------------------------------------------------------   [330]
lcl|Ppa_SMT1_1_1_unnamed_protein_product                                    ------------------------------------------------------------------------------------M---------------------------------------------AKEGARHLLPVF-----DSVHVIEHVMRNPLTLLGS-HRRAGRYRP-------GIGQWYEKY-------HA--------MHGG-------------------------------------------------------------------------DKE----ARK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNYTDMVNKY------YDLV----N--SF-YEYGW-----GE-----------------SYHFAN------------------------RW-R------GET-------------LRESIKRHEHFLALHLH-LK-----------------PGMK-----------VLDVGCGIGGNVLGI-----GAS--VTGLNN-NDTQIARGKVLTEKA--G-------------------------LS-HL----------------VDYMKADF-MKIP--VA--DNTYDAVYTIEASCHAPDPVACYSEIRRVLKPGQLFAGYEWCITDA----------------YN---PGNKDHKRIKEEIEL--GNGLP----------DIRSTRQVLQALKDAGF---EIL-MEEDLAK------HS-Q-VPW--YQPLDPNHFS----------LSTLRLTPIGRFFTHNMV------------------------------------RVLEALKIAPEGSAR-VST----------------FLEQ-----------------------------GMFGLVDG-------GRMEVF---------------------------TPMYYFLSRVSGDRKLGTGNDANLWMIEACSLIWMDHNGSPRLDVKVYHVIVSRLDIG?-------------------------------   [403]
'gi|66805519|ref|XP 636481.1| hypothetical protein DDB0188166 [Dictyostelium discoideum] >gi|60464861|gb|EAL62977.1| hypothetica'     ------------------------------------------------------------------------------------M-------------------------------------------NTQQRAMEGDLSRI---------------------VAI-SRKEKDAVSRNDKVDDTLNGYKELF-------KG--------NDDK-------------------------------------------------------------------------AIQ----ARK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NNYTHMVNTF------YDLA----T--DF-YEFGW-----GQ-----------------SFHFAT------------------------RH-K------YES-------------FEASIARHEMYMAHQLG-LF-----------------PGMK-----------VIDIGCGVGGPMRTIARFS-GAN--VVGLNN-NEYQIQRGKRLNESA--G-------------------------LS-HL----------------CSFIKADF-MHVP--VE--DNTYDCAYQIEATCHAPDLVGLYKEVFRIVKPGGLFGGYEWIMTNK----------------FN---PEDPVEVNIKKQIEL--GNGLP----------DLVKPAEIINAAKAAGF---EVI-TAFDVAE------TS-E-LPW--YLPLSSG-VS----------ITGFLHTGVGRYLTGKFT------------------------------------QLLEIVKLAPAGSYN-TNV----------------WLQN-----------------------------AATFLVQG-------GEKQIF---------------------------SPMFFLLCRKPSTD----------------------------------------------------------------------------   [354]
'gi|40806291|gb|AAR92099.1| S-adenosyl-L-methionine-C-24-delta-sterol-methyltransferase B [Leishmania donovani] >gi|40806289|gb|'     ------------------------------------------------------------------------------------M--------------------------------------------------SAGGRET---------------------APTNLIRRRNKDETNGDVSAAADRFRDRF------------------EKA-------------------------------------------------------------------------TLE----ERK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AATTTMVNEY------YDLV----T--DF-YEYGW-----GQ-----------------NFHFAP------------------------RY-A------GET-------------FFESLARHEYFLAARGG-FM-----------------EGDH-----------IVDVGCGVGGPARNMVRLT-RCN--VIGVNN-NDYQISRARRHDALA--G-------------------------MS-SK----------------IDYVKTDF-CNMS--LA--DNTFDGAYAIEATCHAKDKVKCYSEVFRVIKPGTCFVLYEWCMTDK----------------YN---PNDEYHRTIKHRIEL--GDGLP----------EMETCKQVIEYMKQAGF---VVE-EAIDVISQFESSPIK-S-IPW--YQPLVGDYSS----------LQGLRSTPIGRILTNVMC------------------------------------RVLEFVRLAPKGTYK-ATE----------------VLEE-----------------------------AAESLVVG-------GQLGIF---------------------------TPSFYIRARKPSKQA---------------------------------------------------------------------------   [353]
'gi|619251|gb|AAB31378.1| putative S-adenosylmethionine-dependent methyltransferase [Saccharomyces cerevisiae]'                       ------------------------------------------------------------------------------------MS-----------ET--ELR------------------KRQAQFTRELHGDDIGKKTG---------------------LSA-LMSKNNSAQ-----KEAVQKYLRNW-DGRT-------------DKD-------------------------------------------------------------------------AEE----RRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDYNEATHSY------YNVV----T--DF-YEYGW-----GS-----------------SFHFSR------------------------FY-K------GES-------------FAASIARHEHYLAYKAG-IQ-----------------RGDL-----------VLDVGCGVGGPAREIARFT-GCN--VIGLNN-NDYQIAKAKYYAKKY--N-------------------------LS-DQ----------------MDFVKGDF-MKMD--FE--ENTFDKVYAIEATCHAPKLEGVYSEIYKVLKPGGTFAVYEWVMTDK----------------YD---ENNPEHRKIAYEIEL--GDGIP----------KMFHVDVARKALKNCGF---EVL-VSEDLAD-----NDD-E-IPW--YYPLTGE-WK--YVQNLANLATFFRTSYLGRQFTTAMV------------------------------------TVMEKLGLAPEGSKE-VTA----------------ALEN-----------------------------AAVGLVAG-------GKSKLF---------------------------TPMMLFVARKPENAETPSQTSQEEATQ---------------------------------------------------------------   [384]
'gi|6323635|ref|NP 013706.1| Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol in the ergosterol biosynthe'     ------------------------------------------------------------------------------------MS-----------ET--ELR------------------KRQAQFTRELHGDDIGKKTG---------------------LSA-LMSKNNSAQ-----KEAVQKYLRNW-DGRT-------------DKD-------------------------------------------------------------------------AEE----RRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDYNEATHSY------YNVV----T--DF-YEYGW-----GS-----------------SFHFSR------------------------FY-K------GES-------------FAASIARHEHYLAYKAG-IQ-----------------RGDL-----------VLDVGCGVGGPAREIARFT-GCN--VIGLNN-NDYQIAKAKYYAKKY--N-------------------------LS-DQ----------------MDFVKGDF-MKMD--FE--ENTFDKVYAIEATCHAPKLEGVYSEIYKVLKPGGTFAVYEWVMTDK----------------YD---ENNPEHRKIAYEIEL--GDGIP----------KMFHVDVARKALKNCGF---EVL-VSEDLAD-----NDD-E-IPW--YYPLTGE-WK--YVQNLANLATFFRTSYLGRQFTTAMV------------------------------------TVMEKLGLAPEGSKE-VTA----------------ALEN-----------------------------AAVGLVAG-------GKSKLF---------------------------TPMMLFVARKPENAETPSQTSQ-EATQ---------------------------------------------------------------   [383]
'gi|68129890|emb|CAJ09196.1| sterol 24-c-methyltransferase, putative [Leishmania major]'                                    ------------------------------------------------------------------------------------M--------------------------------------------------SAGGRET---------------------APMNLLRRRNKDEINGDVNAAADRFRNRF------------------EKA-------------------------------------------------------------------------TLE----ERK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AATTTMVNEY------YDLV----T--DF-YEYGW-----GQ-----------------NFHFAP------------------------RY-A------GET-------------FFESLARHEYFLAARGG-FM-----------------EGDH-----------IVDVGCGVGGPARNIVRLT-RCN--VTGVNN-NDYQISRARRHDALA--G-------------------------MS-CK----------------IDYVKTDF-CNMS--LA--DNTFDGAYAIEATCHAKDKVKCYSEVFRVIKPGTCFVLYEWCMTDK----------------YN---PNDEYHRTIKHRIEL--GDGLP----------EMETCKQVIEYMKEAGF---VVE-EAIDVISQFESSPIK-S-IPW--YQPLVGDYSS----------LQGLRSTPIGRILTNIMC------------------------------------RVLEFVHLAPKGTYK-ATE----------------VLEE-----------------------------AAESLVVG-------GQLGIF---------------------------TPSFYIRARKPSKQA---------------------------------------------------------------------------   [353]
'gi|68129891|emb|CAJ09197.1| sterol 24-c-methyltransferase, putative [Leishmania major]'                                    ------------------------------------------------------------------------------------M--------------------------------------------------SAGGREI---------------------TPMNLLRRRNKDEINGDVNAAADRFRNRF------------------EKA-------------------------------------------------------------------------TLE----ERK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AATTTMVNEY------YDLV----T--DF-YEYGW-----GQ-----------------NFHFAP------------------------RY-A------GET-------------FFESLARHEYFLAARGG-FM-----------------EGDH-----------IVDVGCGVGGPARNIVRLT-RCN--VTGVNN-NDYQISRARRHDALA--G-------------------------MS-CK----------------IDYVKTDF-CNMS--LA--DNTFDGAYAIEATCHAKDKVKCYSEVFRVIKPGTCFVLYEWCMTDK----------------YN---PNDEYHRTIKHRIEL--GDGLP----------EMETCKQVIEYMKEAGF---VVE-EAIDVISQFESSPIK-S-IPW--YQPLVGDYSS----------LQGLRSTPIGRILTNIMC------------------------------------RVLEFVHLAPKGTYK-ATE----------------VLEE-----------------------------AAESLVVG-------GQLGIF---------------------------TPSFYIRARKPSKQA---------------------------------------------------------------------------   [353]
'gi|44982886|gb|AAS52116.1| ADR196Wp [Ashbya gossypii ATCC 10895] >gi|45188069|ref|NP 984292.1| ADR196Wp [Eremothecium gossypii]'     ------------------------------------------------------------------------------------MS-----------EQDQELR------------------NRQAQFAKELHGESV-ERSG---------------------LTA-LLGKNREAQ-----QEAVAKYLRHW-DGAT-------------DAE-------------------------------------------------------------------------AEE----RRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADYNESTHSY------YNVV----T--DF-YEYGW-----GA-----------------SFHFSR------------------------FY-T------GES-------------FAMSMARHEHYLAHRAG-IT-----------------SGDL-----------VLDVGCGVGGPAREIARFT-GCR--VVGLNN-NDYQIMKGKHYSRKL--G-------------------------LG-DQ----------------VSYVKGDF-MNMD--FP--DATFDKVYAIEATCHAPSFEGVYGEIYRVLKPGGVFAVYEWVMTEN----------------YD---ETNPEHRRIAYDIEL--GDGIP----------KMYSVKVARDALAKVGF---EIL-VDEDRAD-----NDD-P-VPW--YYPLTGE-WA--YIQTIADLGTFVRTSALGRRVTSAFV------------------------------------SLMETLRLAPRGSSE-VVN----------------ALES-----------------------------AAAGLVAG-------GKSKLF---------------------------TPMMLFVARKPETAE---------------------------------------------------------------------------   [373]
'gi|50555530|ref|XP 505173.1| hypothetical protein [Yarrowia lipolytica] >gi|62900205|sp|Q6C2D9|ERG6 YARLI Sterol 24-C-methyltra'     ------------------------------------------------------------------------------------MS------SNIKLAQ--KDY------------------KGDKEFAAALHGKEGHKKHG---------------------LGA-VMSKNKDAQ-----AAAVEGFFRNW-GDKDRSK---------IEDA-------------------------------------------------------------------------DEQ----GRI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDYAGLTKHY------YNLV----T--DF-YEYGW-----GS-----------------SFHFSR------------------------YY-K------GEA-------------FRQATARHEHYLAYKMG-IQ-----------------PGMK-----------VLDVGCGVGGPAREIARFT-GAN--IVGLNN-NDYQVERGTHYSEVQ--G-------------------------FG-DQ----------------VTYVKGDF-MQMD--FP--DNSFDAVYAIEATVHAPVLEGVYSEIFRVLKPGGVFGVYEWVMTDE----------------YD---ESNPEHRDICYGIEK--GDGIP----------KMYKREVAVKALENVGF---DIE-YQEDLAA-----DDA-E-VPW--YYPLAGE-WK--YVQSLNDIVTIGRTSRLGRMVTMNVI------------------------------------GALEKIGLAPQGSRQ-VTE----------------ALED-----------------------------AAVNLVAG-------GKKKLF---------------------------TPMMLFVSRKPEDKN---------------------------------------------------------------------------   [381]
'gi|71018197|ref|XP 759329.1| hypothetical protein UM03182.1 [Ustilago maydis 521] >gi|46099179|gb|EAK84412.1| hypothetical prot'     ------------------------------------------------------------------------------------M----------------------------------------------------------------------------------APTATDVRN-----NEGIANYTKFW--QKDSKD---------DSAT-------------------------------------------------------------------------DMA----NRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEYTSVVNGY------YDGA----T--DL-YEYGW-----GQ-----------------NFHFAR------------------------YY-P------GEA-------------FMQAIARHEHYLAHQMG-LK-----------------PKMR-----------VLDVGCGVGGPAREIARFA-DVN--IVGLNN-NEYQIQRARKYTEKA--G-------------------------LS-AQ----------------VEFVKGDF-MKLSEQFG--ENRFDAFYAIEATCHAPNFEGIYGEILKVLKPGGIFGVYEWCMTDA----------------WD---PTNPEHKRIAHGIEV--GDGIP----------EMRSIQNARNALKSVGF---QIQ-HEEDLAD-----RGD-K-IPW--YYPIAGS-LS--HCQTVWDYFTVARMTKIGRATTQGAV------------------------------------KLLETLRLVPQGTHS-VGA----------------SLVT-----------------------------AADALVDG-------GRTKLF---------------------------TPMMLFVCRKPSSN----------------------------------------------------------------------------   [347]
'gi|50302283|ref|XP 451076.1| unnamed protein product [Kluyveromyces lactis] >gi|49640207|emb|CAH02664.1| unnamed protein produc'     ------------------------------------------------------------------------------------MS-----------ESN-ELR------------------KRQAEFTKELHGNNV-TKSG---------------------FSA-LVSKNKSAQ-----TEAVAKYLKHW-DGKT-------------DAD-------------------------------------------------------------------------AER----RRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDYNESTHSY------YNVV----T--DF-YEYGW-----GS-----------------SFHFSR------------------------FF-K------GES-------------FSASVARHEHYLAYKAG-IK-----------------ENDL-----------ILDVGCGVGGPARTISRFT-GCN--IIGLNN-NDYQIQKANYYAKRD--H-------------------------LD-SK----------------LSFVKGDF-MKME--FD--ENTFDSVYAIEATCHAPTFEGVYGEIYKVLKPGGTFAVYEWVMTDK----------------YD---ETNPEHRKIAYEIEL--GDGIP----------KMYSVDAARDALSKVGF---EIL-EENDLAD-----NDD-E-IPW--YAPLTGE-WK--YVNSVADLATFFRTSRLGRAFTTSMV------------------------------------TVFEKLGLAPKGSVS-VTN----------------ALEE-----------------------------AAVGLVAG-------GEKKLF---------------------------TPMMLFVAKKPEQK----------------------------------------------------------------------------   [371]
'gi|67541965|ref|XP 664750.1| hypothetical protein AN7146.2 [Aspergillus nidulans FGSC A4] >gi|40742208|gb|EAA61398.1| hypotheti'     ------------------------------------------------------------------------------------M-------APTALEK--ENH------------------QRDAEFNAAMHGNSAQAKGG---------------------FAA-MRQKSAAAQ-----KAAVDEYFKHW-DNKSAET---------ETEE-------------------------------------------------------------------------IRE----ARR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEYATLTRHY------YNLA----T--DL-YEYGW-----GT-----------------SFHFCR------------------------FA-Y------GEP-------------FYQAIARHEHYLAHQMG-IK-----------------PGMK-----------VLDVGCGVGGPAREIVKFT-DAH--VTGLNN-NDYQIQRATRYAERE--G-------------------------LS-HK----------------LNFVKGDF-MQMQ--FP--DNSFDAVYAIEATVHAPELAGVYKEIMRVLKPGGVFGVYEWLMTDA----------------YD---NDNPEHRKIRLGIEQ--GDGIS----------NMVKVSEGLAAIKEAGL---ELL-HHEDLAD-----RPD-E-IPW--YYPLAGS-FK--HMTSPWDFFTIARMTWWGRGLVHRFV------------------------------------GAMETIKLIPQGTQK-TAD----------------SLAL-----------------------------AADCLVAG-------GEKKLF---------------------------TPMYLMVARKPE------------------------------------------------------------------------------   [377]
'gi|83774686|dbj|BAE64809.1| unnamed protein product [Aspergillus oryzae]'                                    ------------------------------------------------------------------------------------M-------APATLEQ--ENH------------------TRDAEFNRVLHGKSSQAQGG---------------------FAAMLGGKDAAAQ-----KAAVDEYFKHW-DNKDAAE---------ETEE-------------------------------------------------------------------------IRA----ARR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEYATLTRHY------YNLA----T--DL-YEYGW-----GT-----------------SFHFCR------------------------FA-Q------GEP-------------FYQAIARHEHYLAHTMG-IK-----------------SGMK-----------VLDVGCGVGGPAREICKFT-DAN--IVGFNN-NDYQIQRATRYAERE--G-------------------------LS-DK----------------LSFVKGDF-MQMS--FP--DNSFDAVYAIEATCHAPELEGVYKEIFRVLKPGGVFGVYEWLMTDE----------------YD---NDNAEHRKIRLGIEQ--GDGIS----------NMVKVSEGLQAFKNAGF---EVL-HNEDLAD-----RPD-A-IPW--YYPLAGS-FK--HMTSPWDFFTIARMTWWGRGIAHRFV------------------------------------GALETIGLAPKGTQK-TAD----------------SLAL-----------------------------AGDCLVAG-------GEKKLF---------------------------TPMYLMVGRKPE------------------------------------------------------------------------------   [378]
'gi|68468297|ref|XP 721708.1| SAM:delta 24-methyltransferase [Candida albicans SC5314] >gi|68468538|ref|XP 721588.1| SAM:delta 2'     ------------------------------------------------------------------------------------M-------SPVQLAE--KNY------------------ERDEQFTKALHGESY-KKTG---------------------LSA-LIAKSKDAA-----SVAAEGYFKHW-DGG-------------ISKD-------------------------------------------------------------------------DEE----KRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NDYSQLTHHY------YNLV----T--DF-YEYGW-----GS-----------------SFHFSR------------------------YY-K------GEA-------------FRQATARHEHFLAHKMN-LN-----------------ENMK-----------VLDVGCGVGGPGREITRFT-DCE--IVGLNN-NDYQIERANHYAKKY--H-------------------------LD-HK----------------LSYVKGDF-MQMD--FE--PESFDAVYAIEATVHAPVLEGVYSEIYKVLKPGGIFGVYEWVMTDK----------------YD---ETNEEHRKIAYGIEV--GDGIP----------KMYSRKVAEQALKNVGF---EIE-YQKDLAD-----VDD-E-IPW--YYPLSGD-LK--FCQTFGDYLTVFRTSRIGRFITTESV------------------------------------GLMEKIGLAPKGSKQ-VTH----------------ALED-----------------------------AAVNLVEG-------GRQKLF---------------------------TPMMLYVVRKPLEKKD--------------------------------------------------------------------------   [376]
'gi|71399753|ref|XP 802864.1| sterol 24-c-methyltransferase [Trypanosoma cruzi strain CL Brener] >gi|70865128|gb|EAN81418.1| ste'     ------------------------------------------------------------------------------------M--------------------------------------------------SAGAPAT---------------------LPLNLMRSRRAEEENKDVSTTANRFRERF--------E--------GKDA-------------------------------------------------------------------------SVS----GRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AETTTMVNEY------YDIV----T--DF-YEYGW-----GQ-----------------GFHFAP------------------------RY-L------GES-------------LLESLARHEFFLAYQGQ-FK-----------------PTDT-----------VLDLGCGVGGPARNIVRLA-GCN--VMGVNN-NEYQISRARRHDTKY--G-------------------------MN-SK----------------INYTKTDF-CNMC--FG--DNEYDGAYAIEATCHATDKVKCFSEVFRVIKPGSYFVLYEWCITEK----------------YD---PNNEEHRRIRHKIEL--GDSLP----------DLETKGQVIEALKASGF---IVE-DSFDVAERFESSPIH-N-LPW--YLTLQGNYTT----------LAGLKCSPLGRWFTNKMC------------------------------------RVLEFAGLAPSGTHK-GAE----------------ILEE-----------------------------AARSLVSG-------GESGIF---------------------------TPSFFAKARKPLPGEKPRK-----------------------------------------------------------------------   [359]
'gi|50421405|ref|XP 459253.1| hypothetical protein DEHA0D19151g [Debaryomyces hansenii CBS767] >gi|49654920|emb|CAG87427.1| unna'     ------------------------------------------------------------------------------------MP------SAVQLAE--KNH------------------EKDSKFAKALHGESY-KQTG---------------------LKA-LMSKARDAS-----EVANDGYFKHW-DGG-------------VTKE-------------------------------------------------------------------------DED----KRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDYSNLTAHY------YNLV----T--DF-YEYGW-----GS-----------------SFHFSR------------------------YY-T------GEA-------------FRQATARHEHFLAHKMQ-IN-----------------ENMK-----------VLDVGCGVGGPAREICRFT-DCS--IVGLNN-NDYQIERANHYARKY--K-------------------------LD-DK----------------LSFVKGDF-MQMD--FE--AESFDAVYAIEATVHAPVLEGVYSEIYKVLKPGGVFGVYEWVMTDK----------------YD---DENEEHRKIAYGIEV--GDGIP----------KMYKREVAEKALKSVGF---EIE-YEADLAD-----KED-D-IPW--YYPLSGE-WK--YVQTLSDYFTIFRTSKVGRTITTEAV------------------------------------GLMEKLGLAPKGSKQ-VTN----------------ALED-----------------------------AAVNLVEG-------GRQKLF---------------------------TPMMLYVCRKPANEDI--------------------------------------------------------------------------   [377]
'gi|71399140|ref|XP 802716.1| sterol 24-c-methyltransferase [Trypanosoma cruzi strain CL Brener] >gi|70864663|gb|EAN81270.1| ste'     ------------------------------------------------------------------------------------M--------------------------------------------------SAGAPDT---------------------LPLNLMRSRKAEEENKDVSTTANRFRERF--------E--------GKDA-------------------------------------------------------------------------SVS----GRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AETTTMVNEY------YDIV----T--DF-YEYGW-----GQ-----------------CFHFAP------------------------RY-L------GES-------------LLESLARHEFFLAYQGQ-FK-----------------PTDT-----------VLDLGCGVGGPARNIVRLA-GCN--VMGVNN-NEYQISRARRHDTKY--G-------------------------MN-SK----------------INYTKTDF-CNMC--FG--DNEYDGAYAIEATCHATDKVKCFSEVFRVIKPGSYFVLYEWCITEK----------------YD---PNNEEHRRIRHKIEL--GDSLP----------DLETKGQVIEALKASGF---IVE-DSFDVAERFESSPIH-N-LPW--YLTLQGNYTT----------LAGLKCSPLGRWFTNKMC------------------------------------RVLEFAGLAPSGTHK-GAE----------------ILEE-----------------------------AARSLVSG-------GESGIF---------------------------TPSFFAKARKPLPGEKPRK-----------------------------------------------------------------------   [359]
'gi|49526306|emb|CAG59930.1| unnamed protein product [Candida glabrata CBS138] >gi|62178560|gb|AAX73200.1| C24 sterol methyltran'     ------------------------------------------------------------------------------------MS-----------ES--ELR------------------QRQAEFTKELHGEGAESRTG---------------------LTA-LLSKNRNAQ-----REAVSKYLRHW-DGKT-------------DKE-------------------------------------------------------------------------AED----RRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDYNEATHSY------YNVV----T--DF-YEYGW-----GS-----------------SFHFSR------------------------FY-K------GEN-------------FQAAMARHEQYLAYMAG-IK-----------------KGDL-----------VLDVGCGVGGPARTIARFT-GCN--IIGLNN-NDYQIQKAKYYAKKY--N-------------------------LQ-DH----------------MDFVKGDF-MNME--FE--PNSFDKVYAIEATCHAPKLEGVYGEIYKVLKPGGTFAVYEWVMTEN----------------YD---ENNEEHRKIAYEIEL--GDGIP----------KMFTVDVAKQALKNVGF---EVE-VSKDLAD-----EDD-E-IPW--YYPLTGE-WK--YVQSLSDIATFFRTSYFGRKFTNCMV------------------------------------SIMEKVGVAPQGSVE-VTA----------------ALEN-----------------------------AAVGLVEG-------GRKKLF---------------------------TPMFLFVAKKPEDAK---------------------------------------------------------------------------   [372]
'gi|57223537|gb|AAW41580.1| sterol 24-C-methyltransferase, putative [Cryptococcus neoformans var. neoformans JEC21] >gi|58262954'     ------------------------------------------------------------------------------------M-------------------------------------------------------------------------------------PAETRS-----ADRVSNYNKFW--EKKSAN---------DNDT-------------------------------------------------------------------------HRA----NRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DQYTEVVNGY------YDGA----T--EL-YEYGW-----AE-----------------SFHFCR------------------------FY-K------GEA-------------FLQALARHEHYLASMMQ-LK-----------------PGMR-----------VLDVGCGVGGPAREIARFS-DAT--IVGVNN-NDFQIGRATAKSKKA--G-------------------------LS-DK----------------VSFVKGDF-MKLSEQFG--ENSFDAIYAIEATCHAPNFEGIYGEIFKCLKPGGVFGVYEWCMTDA----------------WD---PSNPEHKEIAHGIEV--GDGIP----------EMRNLAAARSALKTVGF---EIE-HEEDLAD-----RDD-A-VPW--YYPLEGD-IW--KAQTTWDMFTCWRTSKMGYTITQNAV------------------------------------WFLEKFGLVPKGTYS-VGQ----------------SLIV-----------------------------ASKALVAG-------GRTKLF---------------------------TPMALWVARKPAN-----------------------------------------------------------------------------   [343]
'gi|46122725|ref|XP 385916.1| hypothetical protein FG05740.1 [Gibberella zeae PH-1] >gi|42552972|gb|EAA75815.1| hypothetical pro'     ------------------------------------------------------------------------------------M-------PTTELIS--YDE------------------AQNSAFDNVLHGKSKESRGG---------------------MRA-MMNKDNKAH-----AAAVDEYFQFF-DNKKAED---------EVEA-------------------------------------------------------------------------VRQ----ERT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNYASLTRQY------YNLA----T--DL-YEYGW-----SQ-----------------SFHFCR------------------------FA-Y------GES-------------FDRAIARHEHYLAHNIG-IK-----------------PGMK-----------VLDVGCGVGGPAREIVKFT-GAH--VTGLNI-NEYQVGRAGIYAEKE--G-------------------------LS-DK----------------LKFVQGDF-MKMP--FP--DNSFDAVYAIEATVHAPSLEGVYSEIRRVLKPGGIFGVYEWLMTDI----------------YD---NDDLEQRRIRLDIEL--GDGIA----------QMFKIDHGLSAIKAAGF---ELL-HHEDLAA-----TDDGT-APW--YWPLDSD-MR--YAQNLSDLLTVFRMNKWGRLVMHNLI------------------------------------GVLEACSIAPKGTRK-TAD----------------GLAK-----------------------------GADALVEG-------GKRKLF---------------------------TPMYLMVGKKPEKI----------------------------------------------------------------------------   [380]
'gi|62178558|gb|AAX73199.1| C24 sterol methyltransferase [Candida glabrata]'                                    ------------------------------------------------------------------------------------MS-----------ES--ELR------------------QRQAEFTKELHGEGAESRTG---------------------LTA-LLSKNRNAQ-----REAVSKYLRHW-DGKT-------------DKE-------------------------------------------------------------------------AED----RRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDYNEATHSY------YNVV----T--DF-YEYGW-----GS-----------------SFHFSR------------------------FY-K------GEN-------------FQAAMARHEQYLAYMAG-IK-----------------KGDL-----------VLDVGCGVGGPARTIARFT-GCN--IIGLNN-NDYQIQKAKYYAKKY--N-------------------------LQ-DH----------------MDFVKGDF-MNME--FE--PNSFDKVYAIEATFHAPKLEGVYGEIYKVLKPGGTFAVYEWVMTEN----------------YD---ENNEEHRKIAYEIEL--GDGIP----------KMFTVDVAKQALKNVGF---EVE-VSKDLAD-----EDD-E-IPW--YYPLTGE-WK--YVQSLSDIATFFRTSYFGRKFTNCMV------------------------------------SIMEKVGVAPQGSVE-VTA----------------ALEN-----------------------------AAVGLVEG-------GRKKLF---------------------------TPMFLFVAKKPEDAK---------------------------------------------------------------------------   [372]
'gi|27803704|gb|AAO21936.1| S-adenosylmethionine:D24-methyltransferase [Clavispora lusitaniae] >gi|62900279|sp|Q875K1|ERG6 CLALS'     ------------------------------------------------------------------------------------M-------TSVKLAE--KNF------------------EQDKEFAKAMHGDSY-KKRG---------------------ISA-LMAKAKEAS-----DVATNGYFKHW-DGG-------------VSED-------------------------------------------------------------------------DEK----KRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDYSSLTKNY------YNLV----T--DF-YEYGW-----GS-----------------SFHFSR------------------------YY-K------GEA-------------FRQATARHEHFLAHKMN-IN-----------------ENMR-----------VLDVGCGVGGPGREICRFT-DCT--IVGLNN-NDYQVERAQYYAKKY--K-------------------------LD-DK----------------LSYVKGDF-MQMD--FE--PESFDAVYAIEATVHAPVLEGVYSEIYKVLKPGGVFGVYEWVMTDK----------------YD---ENNEEHRKIAYGIEV--GDGIP----------KMYKREVAEQALKNVGF---DIE-YEKDLAD-----VND-E-IPW--YYPLAGE-WK--YVQTLSDCFTIFRTSKIGRTVTTNVV------------------------------------GLMEKIGLAPKGSKQ-VTG----------------ALED-----------------------------AAVNLVAG-------GEQKLF---------------------------TPMMLYIARKPLDAK---------------------------------------------------------------------------   [375]
'gi|70982043|ref|XP 746550.1| sterol 24-c-methyltransferase [Aspergillus fumigatus Af293] >gi|66844173|gb|EAL84512.1| sterol 24-'     ------------------------------------------------------------------------------------M-------APVALEQ--ENH------------------LRDAEFNRAMHGKSAQFRGG---------------------FAA-LRGKDSAAQ-----KAAVDEYFKHW-DNKPAED---------ETEE-------------------------------------------------------------------------TRA----ARR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEYATLTRHY------YNLA----T--DL-YEYGW-----GT-----------------SFHFCR------------------------FA-Q------GEP-------------FYQAIARHEHYLAHQMG-IK-----------------EGMK-----------VLDVGCGVGGPAREIVKFT-DAN--VVGLNN-NDYQIERATRYAERE--G-------------------------LS-HK----------------LSFVKGDF-MQMK--FP--DNSFDAVYAIEATVHAPDLEGVYKEIFRVLKPGGVFGVYEWLMTDA----------------YD---NDNPEHRRIRLGIEL--GDGIS----------NMVKVSEGLTAFKNAGF---ELL-HNEDLAD-----RPD-A-IPW--YYPLAGS-FK--HMTSPWDFFTIARMTWWGRGIAHRFC------------------------------------GAMETIGLFPKGTQK-TAD----------------SLAI-----------------------------AGDCLVAG-------GEKKLF---------------------------TPMYLMVGRKPE------------------------------------------------------------------------------   [377]
'gi|9367272|emb|CAB97289.1| probable DELTA(24)-STEROL C-METHYLTRANSFERASE (ERG6) [Neurospora crassa] >gi|85118140|ref|XP 965392.'     ------------------------------------------------------------------------------------MP------STIALEK--EDH------------------QRDAEFKKVMHGDSAKAAGG---------------------VAA-LLKKNTEAQ-----QIAVDEYFKHF-DNKTAEA---------ETQA-------------------------------------------------------------------------DRE----ART--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEYATLTRHY------YNLA----T--DI-YEYGW-----GQ-----------------CFHFCR------------------------YS-P------GES-------------FYQAIARHEHYLAAQIG-IK-----------------KDMK-----------VLDVGCGVGGPAREIAKFT-DAH--ITGLNN-NDYQIDRATHYAVRD--G-------------------------LS-GQ----------------LKFVKGDF-MQMS--FP--DNSFDAVYAIEATVHAPKLEGVYGEIYRVLKPGGTFGVYEWLMTDN----------------YD---NDNVEHRDIRLAIEV--GNGIS----------NMVTISEGLAAMKNVGF---ELV-HHEDLAD-----RND-P-MPW--YWPIAGE-LR--YMQSYLDFFTVVRMTHTARRILHGFA------------------------------------GILETVGLAPKGTKK-TAD----------------ALAR-----------------------------GADGLVAG-------AKKKLF---------------------------TPMYLMVGKKPLN-----------------------------------------------------------------------------   [379]
'gi|71738257|gb|AAZ40214.1| sterol methyltransferase [Trypanosoma brucei brucei] >gi|71747750|ref|XP 822930.1| sterol 24-c-methy'     ------------------------------------------------------------------------------------M--------------------------------------------------SAGSRGP---------------------LSLLIARERDANGVNGDVNATAGRLRDRY--------D--------GKGA-------------------------------------------------------------------------SAS----ERR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDATSLTNEY------YDIV----T--DF-YEYGW-----GQ-----------------NFHFAP------------------------RY-M------NET-------------FYESLARYEYFLAYHAQ-FK-----------------PTDT-----------VLDVGCGIGGPARNMVRFT-SCN--VMGVNN-NEYQINRARQHDSRY--G-------------------------MS-GK----------------INYTKTDF-CNMC--FG--DNEFDGAYAIEATCHSESKVKCYSEVFRAIKPGAYFMLYEWCLTDL----------------YD---PANEEHQRVRHGIEL--GDGLP----------ELDTMRQVVAAVKAAGF---VVE-ESFDMAERFESGEPK-S-VPW--YEPLQGSYTS----------LSGLRATPAGRWLTSVTC------------------------------------RLLEAVRLAPAGTCK-ATE----------------ILEE-----------------------------GAVNLVKG-------GELGIF---------------------------TPSFFVKARKPRLGEELSC-----------------------------------------------------------------------   [359]
'gi|19112579|ref|NP 595787.1| hypothetical protein SPBC16E9.05 [Schizosaccharomyces pombe 972h-] >gi|6166151|sp|O14321|ERG6 SCHP'     ------------------------------------------------------------------------------------MSSTALLPP-----------------------------NTDQVLSRRLHGKAAEKKTG---------------------LAA-IASKDVDEQ-----SRKLQEYFEFW--DRNHEN---------ESEE-------------------------------------------------------------------------DRA----RRI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGYKSVVNSY------YDLA----T--DL-YEYGW-----SQ-----------------SFHFSR------------------------FY-K------GEA-------------FAQSIARHEHYLAYRMG-IK-----------------PGSR-----------VLDVGCGVGGPAREITEFT-GCN--LVGLNN-NDYQISRCNNYAVKR--N-------------------------LD-KK----------------QVFVKGDF-MHMP--FE--DNTFDYVYAIEATVHAPSLEGVYGEIFRVLKPGGVFGVYEWVMSDD----------------YD---SSIPKHREIAYNIEV--GDGIP----------QMVRKCDAVEAIKKVGF---NLL-EEDDLTD-----HDNPD-LPW--YYPLTGD-IT--KCQNIWDVFTVFRTSRLGKLVTRYSV------------------------------------QFLEKIGVAAKGTSK-VGD----------------TLAI-----------------------------AQKGLIEG-------GETHLF---------------------------TPMFLMIAKKPETDA---------------------------------------------------------------------------   [378]
'gi|14192727|gb|AAK54439.1| S-adenosyl methionine:sterol methyl transferase [Pneumocystis carinii] >gi|62900323|sp|Q96WX4|ERG6 P'     ------------------------------------------------------------------------------------MS--------FELER--IDI------------------EKDREFSEIMHGKDAAKERG---------------------LLS-SFRKDKEAQ-----KIALDSYFGFW-GDKCTSE---------KNDI-------------------------------------------------------------------------HQQ----ERF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KFYATLTRHY------YNLV----T--DF-YEYGW-----ST-----------------SFHFCR------------------------FA-K------DES-------------FSQAIARHEHYIALHAG-IR-----------------EGET-----------VLDVGCGVGGPACQISVFT-GAN--IVGLNN-NDYQIQRAKYYSEKK--G-------------------------LS-DK----------------LKFIKGDF-MQMP--FP--ENSFDKIYSIEATIHAPSLEGVYSEIYRVLKPGGLYASYEWVMLNK----------------YD---ENDPEHQQIVYGIEI--GDSIP----------KISKIGEAEAALIKVGF---EII-HSEELST-----KNS-P-LPW--YYYLDGD-LR--KVRSFRDFISIARMTTIGKWLISSFI------------------------------------GLMEFIGLLPKGSKK-VND----------------ILLV-----------------------------AADSLVKA-------GKKEIF---------------------------TPMQLWVCRKPLV-----------------------------------------------------------------------------   [377]
'gi|46111803|ref|XP 382959.1| hypothetical protein FG02783.1 [Gibberella zeae PH-1] >gi|42547935|gb|EAA70778.1| hypothetical pro'     ------------------------------------------------------------------------------------MV----ASSNTGLER--EDH------------------QRDADFNKAMHGSSAQARGG---------------------VAA-MFRKGGAAK-----QAAVDEYFKHW-DNKPAEN---------ETPE-------------------------------------------------------------------------ERA----ARQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEYATLTRHY------YNLA----T--DL-YEYGW-----GQ-----------------SFHFCR------------------------FS-Q------GEP-------------FYQAIARHEHYLAHQIG-IK-----------------DGMK-----------VLDVGCGVGGPAREIAKFT-GAH--ITGLNN-NNYQIERATHYAFKE--G-------------------------LS-NQ----------------LEFVKGDF-MQMS--FP--DNSFDAVYAIEATVHAPTLKGIYSEIFRVLKPGGVFGVYEWLMTDE----------------YD---NDNLRHREIRLGIEQ--GDGIS----------NMCKVSEGIAAIHDSGF---EML-HHEDLAD-----RPD-A-LPW--YWPLAGE-LR--YVQTVGDFFTIVRMTTWGRTIAHGLA------------------------------------GLLETFKLAPAGTKK-TAD----------------SLAL-----------------------------AADCLVAG-------GRDKLF---------------------------TPMYLMVARKPAA-----------------------------------------------------------------------------   [381]
'gi|41688402|dbj|BAA13793.2| unnamed protein product [Schizosaccharomyces pombe]'                                    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RA----RRI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGYKSVVNSY------YDLA----T--DL-YEYGW-----SQ-----------------SFHFSR------------------------FY-K------GEA-------------FAQSIARHEHYLAYRMG-IK-----------------PGSR-----------VLDVGCGVGGPAREITEFT-GCN--LVGLNN-NDYQISRCNNYAVKR--N-------------------------LD-KK----------------QVFVKGDF-MHMP--FE--DNTFDYVYAIEATVHAPSLEGVYGEIFRVLKPGGVFGVYEWVMSDD----------------YD---SSIPKHREIAYNIEV--GDGIP----------QMVRKCDAVEAIKKVGF---NLL-EEDDLTD-----HDNPD-LPW--YYPLTGD-IT--KCQNIWDVFTVFRTSRLGKLVTRYSV------------------------------------QFLEKIGVAAKGTSK-VGD----------------TLAI-----------------------------AQKGLIEG-------GETHLF---------------------------TPMFLMIAKKPETDA---------------------------------------------------------------------------   [315]
'gi|12642580|gb|AAK00294.1| sterol methyl transferase [Pneumocystis carinii f. sp. carinii]'                                    -----------------------------------------------------------------------------------------------------------------------------------MHGKDAAKERG---------------------LLS-SFRRIKKPK-----TERLDSYFGFW-GDKCTSEK--------KNDV-------------------------------------------------------------------------HPP----ERF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KFYATLTRHY------YSLV----T--DF-YEYGW-----SI-----------------SFHFCR------------------------LC-K------NES-------------FSQAIARHEHYIALHAG-IR-----------------EGET-----------VLDVGCGVGGPDCQISVFT-GAN--IVGLNN-NDYQIQRAKYYSEKK--G-------------------------LS-DK----------------LKFIKGDF-MQMP--FP--ENSFDKIYSIEATIHAPSLEGVYSEIYRVLKPGGLYASYEWVMLTE----------------YD---ENDPEHQQIVYGIEI--GDSIP----------KISKIGEAEAALIKVGF---EII-HSEELST-----KNS-P-LPW--YYYLDGY-LK--RVRSFRDFISIARMTTIGKWLISSFI------------------------------------GLMEFIGLLPKGSKK-VND----------------ILLV-----------------------------AADSLVKA-------GKKEIF---------------------------TPMQLWVCRKPLV-----------------------------------------------------------------------------   [359]
'gi|88182054|gb|EAQ89522.1| conserved hypothetical protein [Chaetomium globosum CBS 148.51]'                                    ------------------------------------------------------------------------------------MA----PLAKAALEK--EDH------------------QRDAAFMKALHGKSTEAAGG---------------------FAA-MLSKDKDAK-----ELAVNEYFKHF-DNKSAET---------ETDA-------------------------------------------------------------------------DRE----ART--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEYATLTRHY------YNLA----T--DL-YEYGW-----GQ-----------------SFHFCR------------------------YS-I------GES-------------FYQAIARHEHYLAMKVG-IQ-----------------AGMK-----------VLDVGCGIGGPAREIAKFT-DAH--ITGLNN-NDYQIQRATRYAAQE--G-------------------------LS-NQ----------------LKYVKGDF-MQMS--FA--DESFDAVYAIEATVHAPKLEGVYSEIFRVLKPGGVFGVYEWLMTDN----------------YD---NNNLEHRDIRLAIEE--GNGIS----------NMVTISEGLAAMKAAGF---ELM-HHEDLTK-----RGD-S-IPW--YWGIAGE-TK--YMQSYWDLFTVLRMTHTGRRAVHVFT------------------------------------GLLETIGLAPKGTKK-TAD----------------SLAK-----------------------------GADGLVAG-------AKKDLF---------------------------TPMYLMVGRKPAN-----------------------------------------------------------------------------   [381]
'gi|39942022|ref|XP 360548.1| hypothetical protein MG10860.4 [Magnaporthe grisea 70-15]'                                    -----------------------------------------------------------------------------------------------------------------------------MTFEKVLHKGSSANTGG---------------------IGS-MLGKDREAS-----KAAINEYFQHW-DGKTAKN---------ETSE-------------------------------------------------------------------------VRE----ARK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADYATLTRQY------YNLA----T--DF-YEYGW-----CQ-----------------SFHFCR------------------------FA-H------GET-------------FASAIARHEHTLAHRIG-IK-----------------KDMK-----------VLDVGCGVGGPARQMAKFT-GAN--ITGITI-NEYQVERATRYAELE--G-------------------------LS-RQ----------------LQFVQGDF-MSLP--FE--EETFDAVYAIEATVHAPVLEDVYRQVYNVLKPGGVFGLYEWVMTDA----------------YD---DNNLRHRDIRLGIEQ--GDGIA----------NMQTAKTAVEAIKAAGF---ELL-EVEDLSQSTDGGNST-R-APW--YWPLDGSSWR--CANTIGDVLGTFRMTPAGRTVAHAML------------------------------------TVMEAVGLAPPGTKK-TAD----------------SLAR-----------------------------AADALVAG-------GKEGLF---------------------------TPMFLMVARKPFAEE---------------------------------------------------------------------------   [372]
'gi|83770900|dbj|BAE61033.1| unnamed protein product [Aspergillus oryzae]'                                    ------------------------------------------------------------------------------------MT--------VALQE-----------------------DPDLALTKDMHGKSAEEKNA---------------------FFA-MLKKNNAAH-----REITNEYVRRWRTEKGIDG---------TTDE-------------------------------------------------------------------------ARK----ERT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TEYMGVVNNY------YDLV----T--DF-YEEAW-----AQ-----------------SFHFCR------------------------FT-V------GES-------------FLQALARHEHYLAYKLG-IK-----------------RGME-----------VLDVGCGVGGPAREIARFT-GCQ--VVGVNN-NGYQIARATRHTQKA--G-------------------------LE-EQ----------------VSFCKGDF-MHLD--FP--DNKFDAVYVIEATVHAPSLQKVYEQIFRVLKPGGRFGVYEWVMTDR----------------FD---ESNPKHRAIRLGIER--GNGIV----------NMCTQNEAAEAIQAAGF---VLE-HEEDLAA-----RPD-P-IPW--YYPIAGE-LR--HARSLWDLLTVLRMTKLGRGAMGYLL------------------------------------WTLENLRLAPSGTAE-TAT----------------ELAS-----------------------------GADSLVEG-------GRLGLF---------------------------TPMYFMIGRKPEI-----------------------------------------------------------------------------   [375]
'gnl|CMER|CMP275C probable 24-sterol C-methyltransferase'                                    ------------------------------------------------------------------------------------MTKRTKDSTPGARESIRKGTGARQSARNRRFTLLKVPIRKDGGLWQLATAKSADAAAN-------------FWEFLFRFLPV-VGRRGHTKTTGKSTEEELREYLTLF-----ARGS--------GSAE-------------------------------------------------------------------------DIA----LRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRYKELSNGM------YDIA----T--DF-YEWGW-----GP-----------------SFHFAV------------------------YG-P------DET-------------FREATRRYEYTIALRLK-LD-----------------PGAA-----------VIDLGCGVGGPLRNIARFA-RCQ--IVGVNI-CDYQILRGLRYIEDD--G-------------------------LM-DQ----------------CTIIKADF-NNLP--FE--ENSKDGAYQIEATCHSPDKLKTYGEVFRVLKPGARFVGYEWALTDR----------------FD---AAASEHQRLKFGIEI--GNGIP----------DLMKTEEIVNAMRQVGF---QIE-DAYDATT------LS-I-KPW--YTPLSGENAF--H-------WSGFRHTRLGHYMTHALV------------------------------------SALETVRIAPRGSAK-MSR----------------TLMD-----------------------------GARDLIAA-------GKLGIF---------------------------TPSFFIVARKPLDKQANAQA----------------------------------------------------------------------   [415]
'gi|39969919|ref|XP 366350.1| hypothetical protein MG10568.4 [Magnaporthe grisea 70-15] >gi|86196071|gb|EAQ70709.1| hypothetical'     ------------------------------------------------------------------------------------MG----A-PKQGLEK--EDK------------------KRDAEFNKALHGQSALAAGG---------------------IAA-MFSKDKEAK-----KLAVDEYFKHF-DNKTAAN---------ETPE-------------------------------------------------------------------------ERA----ARQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEYATLTRHY------YNLA----T--DI-YEYGW-----GQ-----------------SFHFCR------------------------FS-H------NES-------------FYQAIARHEHYLAHQIG-IK-----------------EGMT-----------VLDVGCGVGGPAREIAKFT-GCN--VVGLNN-NDYQIDRATHYAKQE--K-------------------------LD-SQ----------------LQFVKGDF-MQMS--FP--DESFDAVYAIEATVHAPKLEGVYSEIFRVLKPGGTFGVYEWLMTDD----------------YD---NDNLHHRDIRLKIEL--GNGIS----------NMVPISEGEAAMRAAGF---EII-KTDDLAQ-----KGD-E-LPW--YWPLAGD-LK--YLQSYFDLFTVLRMTKWARTCLHGMA------------------------------------GVLEAVGVAPAGTKK-TAD----------------ALAT-----------------------------GGDALVAG-------AKENIF---------------------------TPMYLMVGRKPMN-----------------------------------------------------------------------------   [380]
'gi|71399535|ref|XP 802811.1| sterol 24-c-methyltransferase [Trypanosoma cruzi strain CL Brener] >gi|70864963|gb|EAN81365.1| ste'     ----------------------------------------------------------------------------------------------------------------------------------------------------------------------NLMRSRRAEEENKDVSTTANRFRERF--------E--------GKDA-------------------------------------------------------------------------SVS----GRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AETTTMVNEY------YDIV----T--DF-YEYGW-----GQ-----------------CFHFAP------------------------RY-L------GES-------------LLESLARHEFFLAYQGQ-FK-----------------PTDT-----------VLDLGCGVGGPARNIVRLA-GCN--VMGVNN-NEYQISRARRHDTKY--G-------------------------MN-SK----------------INYTKTDF-CNMC--FG--DNEYDGAYAIEATCHATDKVKCFSEVFRVIKPGSYFVLYEWCITEK----------------YD---PNNEEHRRIRHKIEL--GDSLP----------DLETKGQVIEALKASGF---IVE-DSFDVAERFESSPIH-N-LPW--YLTLQGNYTT----------LAGLKCSPLGRWFTNKMC------------------------------------RVLEFAGLAPSGTHK-GG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [310]
'gi|39944670|ref|XP 361872.1| hypothetical protein MG04346.4 [Magnaporthe grisea 70-15]'                                    ------------------------------------------------------------------------------------MSKQQHPSSKTQITR--RRD------------------TADMTFEQVLHKGSSANMGG---------------------LSS-MLGKDREAS-----KTAVDQYFRHW-DGKTAKT---------ETTK-------------------------------------------------------------------------VRE----ERK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADYATLTRQY------YNLV----T--DF-YEYGW-----GQ-----------------SFHFCT------------------------FA-P------GET-------------FASAITRYEHTLAHRIG-IK-----------------KGMK-----------VLDIGCGVGGPARQIAKFT-GAN--ITGITI-NEYQVERARRYAEMEGYG-------------------------AG-EQ----------------LKFVQGDF-MALP--FE--KETFDAVYSIEATVHAPKLEDVYKQIFNVLKPGGIFGLYEWVMTDA----------------YD---ENDPHHKEIRFGIEH--GGGIA----------NLQTAQTAIAAIKAAGF---ELL-ESEDLAD-----NSD-R-APW--YWPLGGNAWQ--YASTFGDILSTFTMTPAGRAIAHTVL------------------------------------GVVESIGLVPPGTKK-TAD----------------SLST-----------------------------TAAALVAG-------GKEGLF---------------------------TPMFLMVARKPVAKE---------------------------------------------------------------------------   [390]
'gi|59802827|gb|AAX07631.1| sterol 24-C-methyltransferase-like protein [Magnaporthe grisea] >gi|62900141|sp|Q5EN22|ERG6 MAGGR St'     ------------------------------------------------------------------------------------MSKQQHPSSKTQITR--RRD------------------TADMTFEQVLHKGSSANMGG---------------------LSS-MLGKDREAS-----KTAVDQYFRHW-DGKTAKT---------ETTK-------------------------------------------------------------------------VRE----ERK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADYATLTRQY------YNLV----T--DF-YEYGW-----GQ-----------------SFHFCT------------------------FA-P------GET-------------FASAITRYEHTLAHRIG-IK-----------------KGMK-----------VLDIGCGVGGPARQIAKFT-GAN--ITGITI-NEYQVERARRYAEMEGYG-------------------------AG-EQ----------------LKFVQGDF-MALP--FE--KETFDAVYSIEATVHAPKLEDVYKQIFNVLKPGGIFGLYEWVMTNA----------------YD---ENDPHHKEIRFGIEH--GGGIA----------NLQTAQTAIAAIKAAGF---ELL-ESEDLAD-----NSD-R-APW--YWPLGGNAWQ--YASTFGDILSTFTMTPAGRAIAHTVL------------------------------------GVVESIGLVPPGTKK-TAD----------------SLST-----------------------------TAAALVAG-------GKEGLF---------------------------TPMFLMVARKPVAKE---------------------------------------------------------------------------   [390]
lcl|Smo_SMT1_1_1_unnamed_protein_product                                    ------------------------------------------------------------------------------------M---------------------------------------------AKAGA-MDLASG---------------------LGG-NLSRRDLAS-------AV-DQYEKY-------HS--------FYGG-------------------------------------------------------------------------EED----KRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FNYTDMVNKY------YDLA----T--SF-YEYGW-----GQ-----------------SFHFAN------------------------RF-Q------DET-------------LQESIKRHEHFLALHLG-LK-----------------PEMKVIYLSMRKLDEVLDVGCGIGGPLREIARFS-GAS--ITGLNN-NGYQISRGTELNKKY--G-------------------------LD-KT----------------CDFVKADF-MKMP--LA--DNTYDAVYAIEATCHAPDA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [195]
lcl|Ppa_SMT1_12_1_unnamed_protein_product                                    ----------------------------------------------------------------------------------------------------------------------------------------MGAMGAGAYYMLVMTGAAERKGKRAVDLGGGSITREQVKS-------SYQKYASFF--------E--------K--P-------------------------------------------------------------------------KQI----EAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNVPNFVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------AV-P------GKS-------------HKESTRIHEERVVDLLG-LK-----------------PGEK-----------VLDVGCGVGGPMRAIAAYS-QAF--VTGITI-NDYQVERARSHNKKA--G-------------------------LD-RL----------------CEVVCGNF-LQMP--FE--DNSFDGAYSIEATCHAPELKDVYSEVFRVLKPGHLYVTYEWVTTPL----------------FR---ADNAEHVECIHGIEH--GDALP----------GLRSYKQVGEIAKEVGF---VVL-EDRDLAL-----PP--A-KPW--WTRL--------------------KMGRLAYYRNHLMI------------------------------------ALLSFLGIAPKGVVD-VHE----------------MLFK-----------------------------TADHLTRG-------GETGIF---------------------------SPMHLLLLQKPEKS-------------S--------------------------------------------------------------   [349]
'gi|2246454|gb|AAB62808.1| S-adenosyl-methionine-sterol-C- methyltransferase [Nicotiana tabacum]'                                    ------------------------------------------------------------------------------------M------------------------------------------DSLTLICTAALLAAGGLYWFVCILGSAEVKGKRAVQLSGGSIEKENVQD-------NYKQYWSFF--------R--------R--P-------------------------------------------------------------------------KEI----ETA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DKVPAFVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------SI-P------GKS-------------HREATRIHEEMAVDLIG-VK-----------------PGAR-----------ILDAGCGVGGPMRAIAAHS-RAN--VVGITI-NEYQVKRARMHNKKA--G-------------------------LD-SL----------------CEVVCGNF-LQMP--FP--DNSFDGAYSIEATCHAPKLEEVYKEIYRVMKPGSLYVSYEWVTTEL----------------YR---PEDPEHVEIIHGIER--GDALP----------GLRSYKDIAEVAKKVGF---EVV-KEKDLAR-----PP--S-NPW--WTRL--------------------KMGRIAYWRNHILV------------------------------------TILAFLGIAPKGTVD-VHE----------------MLFV-----------------------------TADYLSKG-------GEKGIF---------------------------SPMHMILCRKPEE-----------------------------------------------------------------------------   [357]
lcl|Ppa_SMT1_8_1_unnamed_protein_product                                    ------------------------------------------------------------------------------------M-------------------------------------------TWGMFWGAMGALGAGAYYVLVLAGAAERKGKRAVDLGGGSITREQVRS-------SYQKYASFF--------E--------K--P-------------------------------------------------------------------------KQI----EAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNVPNFVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------AV-P------GKS-------------HKESTRLHEERVVDLLG-VK-----------------PGQK-----------VLDVGCGVGGPMRAIAAYS-QAH--VTGITI-NDYQVARARSHNKKA--G-------------------------LD-NL----------------CEVVCGNF-LFMP--FE--NNSFDGAYSIEATCHAPELKDVYAEVFRVLKPGHLYVTYEWVTTPL----------------FR---ADNAEHVECIHGIEH--GDALP----------GLRSYKQVGEIAKEVGF---KVL-EDRDLAL-----PP--A-KPW--WIRL--------------------KMGRLAYYRNHLVI------------------------------------ALLSFLGIAPKGVVD-VHE----------------MLFK-----------------------------TADHLTRG-------GETGIF---------------------------SPMHLLVLQKPEEG-------------L--------------------------------------------------------------   [358]
'gi|2246452|gb|AAB62807.1| S-adenosyl-methionine-sterol-C-methyltransferase homolog [Nicotiana tabacum]'                              ------------------------------------------------------------------------------------A------------------------------------------RA-----TASLL-AGGLYWFVCILGSAEIKGKRAVNLSGGFIAKEKVQD-------KYKQYWSFF--------R--------R--P-------------------------------------------------------------------------KEI----ETT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ENVPAFVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------AI-T------GKF-------------HREATRLHEEMAVDLLG-IK-----------------PGAR-----------VLDAGCGVGGPMRAIAAHS-GAN--IVGITI-NEYQVNRARAHNKKA--G-------------------------LD-SQ----------------CEVVCGNF-LQMP--FD--DNSFDGVYSIEATCHAPKLEEVYSEIYRVLKPGSMYVSYEWVTTEL----------------YN---SDDPEHVKIIHGIER--GDALP----------GLRNYSDIADVARAVGF---EVV-KEKDLAK-----PP--A-NPW--WTRL--------------------KMGRIAYWRNHIVV------------------------------------TVLSWLGIAPKGTVD-VHK----------------MLFV-----------------------------TADYLAKG-------GDKGIF---------------------------SPMHMILCRKPEEH----------------------------------------------------------------------------   [352]
lcl|Ppa_SMT1_5_1_unnamed_protein_product                                    ------------------------------------------------------------------------------------M-------------------------------------------SWGMFWGVMGAMGAAAYYLLVLAGAAERKGKRAVDLGGGSITREQVKS-------SYQKYASFF--------E--------K--P-------------------------------------------------------------------------KQI----EAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNVPNFVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------AV-P------GRS-------------HKESTRIHEERVVDLLG-VK-----------------PGQK-----------VLDVGCGVGGPMRAIASYS-QSH--VTGITI-NDYQVARARSHNKKA--G-------------------------LD-EI----------------CEVVCGNF-LQMP--FE--DSSFDGAYSIEATCHAPELKDVYSEVFRVLKPGHLYVTYEWVTTPL----------------FR---ADNTLHVECIHGIEH--GDALP----------GLRSYKQVGEIAKQVGF---KVL-EDKDLAL-----PP--A-QPW--WTRL--------------------KMGRLAYYRNHLVI------------------------------------ALLSFLGIAPKGVVD-VHE----------------MLFK-----------------------------TADHLTRG-------GEMGIF---------------------------SPMHLLVLQKPEEC-------------S--------------------------------------------------------------   [358]
lcl|7882_Cre_unnamed_protein_product                                    ------------------------------------------------------------------------------------MAVALPAAVTSAYERLAG--------------------EFDKLSTTQKYAVGIAGGVTSLYLLAKVLKGSDRDKPTTLQLSGGSIDSSKVKD-------EFTAYADSY--------G--------KNAG-------------------------------------------------------------------------EGI----TDR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKTVHLVDVF------YSLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------KL-P------NKD-------------LKASEAAHEARIAALLR-LQ-----------------PGQK-----------ALDCGCGVGGPMRTVAAVS-GAH--ITGITI-NQYQVDRAKTHNARQ--G-------------------------LA-PL----------------TDVVRGDF-TNMP--FK--ENTFDGAYAIEATCHAPKLEQVYGEIYRVLKPGSYFVSYEWVSTQK----------------FD---VNNAEHVKIMDEINF--GNGLP----------EMRTWKEAEDAGKNVGF---ELV-MSLDLAT-----ASVVA-GPW--YERL--------------------RMGKYTHAINHGIV------------------------------------STVDALGLAPKGLKE-VHH----------------MLVE-----------------------------VAKSLIQG-------GESGIF---------------------------TPMHLLLFRKPGAD-----------KKK--------------------------------------------------------------   [387]
'gi|15222955|ref|NP 177736.1| SMT3; S-adenosylmethionine-dependent methyltransferase [Arabidopsis thaliana] >gi|21360447|gb|AAM4'     ------------------------------------------------------------------------------------M------------------------------------------DSVALYCTAGLI-AGAVYWFICVLGPAERKGKRASDLSGGSISAEKVKD-------NYNQYWSFF--------R--------K--P-------------------------------------------------------------------------KEI----ESA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKVPDFVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------HV-P------GKS-------------DKDATRIHEEMAVDLIK-VK-----------------PGQK-----------ILDAGCGVGGPMRAIAAHS-KAQ--VTGITI-NEYQVQRAKLHNKKA--G-------------------------LD-SL----------------CNVVCGNF-LKMP--FD--ENTFDGAYSIEATCHAPKLEEVYSEIFRVMKPGSLFVSYEWVTTEK----------------YR---DDDEEHKDVIQGIER--GDALP----------GLRSYADIAVTAKKVGF---EVV-KEKDLAK-----PP--S-KPW--WNRL--------------------KMGRIAYWRNHVVV------------------------------------VILSAIGVAPKGTVD-VHK----------------MLFK-----------------------------TADYLTRG-------GETGIF---------------------------SPMHMILCRKPEKA----------SE----------------------------------------------------------------   [359]
'gi|2246456|gb|AAB62809.1| S-adenosyl-methionine-sterol-C-methyltransferase [Arabidopsis thaliana]'                                   ------------------------------------------------------------------------------------M------------------------------------------DSVALYCTAGLI-AGAVYWFICVLGPAERKGKRASDLSGGSISAEKVKD-------NYNQYWSFF--------R--------K--P-------------------------------------------------------------------------KEI----ESA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKVPDFVDTF------YNLV----T--DT-YEWGW-----GQ-----------------SFHFSP------------------------HV-P------GKS-------------DKDATRIHEEMAVDLIK-VK-----------------PGQK-----------ILDAGCGVGGPMRAIAAHS-KAQ--VTGITI-NEYQVQRAKLHNKKA--G-------------------------LD-SL----------------CNVVCGNF-LKMP--FD--ENTFDGAYSIEATCHAPKLEEVYSEIFRVMKPGSLFVSYEWVTTEK----------------YR---DDDEEHKDVIQGIER--GDALP----------GLRSYADIAVTAKKVGF---EVV-KEKDLAK-----PP--S-KPW--WNRL--------------------KMGRIAYWRNHVVV------------------------------------VILSAIGVAPKGTVD-VHK----------------MLFK-----------------------------TADYLTRG-------GETGIF---------------------------SPMHMILCRKPEKA----------SE----------------------------------------------------------------   [359]
'gi|22136020|gb|AAM91592.1| 24-sterol C-methyltransferase [Arabidopsis thaliana] >gi|25083682|gb|AAN72104.1| 24-sterol C-methylt'     ------------------------------------------------------------------------------------M------------------------------------------DSLTLFFTGALV-AVGIYWFLCVLGPAERKGKRAVDLSGGSISAEKVQD-------NYKQYWSFF--------R--------R--P-------------------------------------------------------------------------KEI----ETA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKVPDFVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------SI-P------GKS-------------HKDATRLHEEMAVDLIQ-VK-----------------PGQK-----------ILDVGCGVGGPMRAIASHS-RAN--VVGITI-NEYQVNRARLHNKKA--G-------------------------LD-AL----------------CEVVCGNF-LQMP--FD--DNSFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSMYVSYEWVTTEK----------------FK---AEDDEHVEVIQGIER--GDALP----------GLRAYVDIAETAKKVGF---EIV-KEKDLAS-----PP--A-EPW--WTRL--------------------KMGRLAYWRNHIVV------------------------------------QILSAVGVAPKGTVD-VHE----------------MLFK-----------------------------TADYLTRG-------GQTGIF---------------------------SPMHMILCRKPESP----------EESS--------------------------------------------------------------   [361]
'gi|1061040|emb|CAA61966.1| sterol-C-methyltransferase [Arabidopsis thaliana] >gi|1587694|prf||2207220A sterol C-methyltransfera'     ------------------------------------------------------------------------------------M------------------------------------------DSLTLFFTGALV-AVGIYWFLCVLGPAERKGKRAVDLSGGSISAEKVQD-------NYKQYWSFF--------R--------R--P-------------------------------------------------------------------------KEI----ETA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKVPDFVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------SI-P------GKS-------------HKDATRLHEEMAVDLIQ-VK-----------------PGQK-----------ILDVGCGVGGPMRAIASHS-RAN--VVGITI-NEYQVNRARLHNKKA--G-------------------------LD-AL----------------CEVVCGNF-LQMP--FD--DNSFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSMYVSYEWVTTEK----------------FK---AEDDEHVEVIQGIER--GDALP----------GLRAYVDIAETAKKVGF---EIV-KEKDLAS-----PP--A-EPW--WTRL--------------------KMGRLAYWRNHIVV------------------------------------QILSAVGVAPKGTVD-VHE----------------MLFK-----------------------------TADCLTRG-------GETGIF---------------------------SPMHMILCRKPESP----------EESS--------------------------------------------------------------   [361]
'gi|15217917|ref|NP 173458.1| SMT2 (STEROL METHYLTRANSFERASE 2) [Arabidopsis thaliana] >gi|12083242|gb|AAG48780.1| putative ster'     ------------------------------------------------------------------------------------M------------------------------------------DSLTLFFTGALV-AVGIYWFLCVLGPAERKGKRAVDLSGGSISAEKVQD-------NYKQYWSFF--------R--------R--P-------------------------------------------------------------------------KEI----ETA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKVPDFVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------SI-P------GKS-------------HKDATRLHEEMAVDLIQ-VK-----------------PGQK-----------ILDVGCGVGGPMRAIASHS-RAN--VVGITI-NEYQVNRARLHNKKA--G-------------------------LD-AL----------------CEVVCGNF-LQMP--FD--DNSFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSMYVSYEWVTTEK----------------FK---AEDDEHVEVIQGIER--GDALP----------GLRAYVDIAETAKKVGF---EIV-KEKDLAS-----PP--A-EPW--WTRL--------------------KMGRLAYWRNHIVV------------------------------------QILSAVGVAPKGTVD-VHE----------------MLFK-----------------------------TADYLTRG-------GETGIF---------------------------SPMHMILCRKPESP----------EESS--------------------------------------------------------------   [361]
'gi|23397216|gb|AAN31890.1| putative sterol-C-methyltransferase [Arabidopsis thaliana]'                                    ------------------------------------------------------------------------------------M------------------------------------------DSLTLFFTGALV-AVGIYWFLCVLGPAERKGKRAVDLSGGSISAEKVQD-------NYKQYWSFF--------R--------R--P-------------------------------------------------------------------------KEI----ETA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKVPDFVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------SI-P------GKS-------------HKDATRLHEEMAVDLIQ-VK-----------------PGQK-----------ILDVGCGVGGPMRAIASHS-RAN--VVGITI-NEYQVNRARLHNKKA--G-------------------------LD-AL----------------CEVVCGNF-LQMP--FD--DNSFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSMYVSYEWVTTEK----------------FK---AEDDEHVEVIQGIER--GDALP----------GLRAYVDIAETAKKVGF---EIV-KEKDLAS-----PP--A-EPW--WTRL--------------------KMGRLAYWRNHIVV------------------------------------QILSAVGVAPKGTVD-VHE----------------MLFK-----------------------------TADYLTRG-------GETGIF---------------------------SPMHMILCRKAESP----------EESS--------------------------------------------------------------   [361]
'gi|21555010|gb|AAM63753.1| sterol-C-methyltransferase [Arabidopsis thaliana]'                                    ------------------------------------------------------------------------------------M------------------------------------------DSLTLFFTGALV-AVGIYWFLCVLGPAERKGKRAVDLSGGSISAEKVQD-------NYKQYWSFF--------R--------R--P-------------------------------------------------------------------------KEI----ETA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKVPDFVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------SI-P------GKS-------------HKDATRLHEEMAVDLIQ-VK-----------------PGQK-----------ILDVG?GVGG?MRAIASHS-RAN--VVGITI-NEYQVNRARLHNKKA--G-------------------------LD-AL----------------CEVVCGNF-LQMP--FD--DNSFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSMYVSYEWVTTEK----------------FK---AEDDEHVEVIQGIER--GDALP----------GLRAYVDIAETAKKVGF---EIV-KEKDLAS-----PP--A-EPW--WTRL--------------------KMGRLAYWRNHIVV------------------------------------QILSAVGVAPKGTVD-VHE----------------MLFK-----------------------------TADYLTRG-------GETGIF---------------------------SPMHMILCRKPESP----------EESS--------------------------------------------------------------   [361]
lcl|Smo_SMT1_10_1_unnamed_protein_product                                    ------------------------------------------------------------------------------------M------------------------------------------VTWGLLGTGAAMAAAGLYWAMCVAGSAEQKGKRAVDLGGGSLSRGEVAG-------NYREYAAFF--------D--------K--P-------------------------------------------------------------------------QQI----AAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DKVPKLVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------AV-P------GVG-------------HREETKLHEKYVADLLE-LG-----------------PGQR-----------VLDAGCGVGGPMRTIAAHS-GSN--VVGITI-NDYQVARARSHNSKA--G-------------------------LS-KL----------------CEVICGDF-LHMP--FG--DDSFDAAYSIEATCHAPQLRDVYAEIYRVLKPGKLYVSYEWVTTCK----------------YQ---AQDPEHVKIIHEIEH--GNALP----------GLRSYKQVVEIAKEVGF---EVL-EDRDLAL-----PP--A-HPW--WTRL--------------------KMGRLAYYRNHVVI------------------------------------ALLSFLGIAPQGVFE-VHE----------------MLFK-----------------------------TAMYLTRG-------GETGIF---------------------------SPMHLLVCRKPLDGGDAATAATAAVASS--------------------------------------------------------------   [372]
'gi|4122|emb|CAA37826.1| unnamed protein product [Saccharomyces cerevisiae]'                                    ------------------------------------------------------------------------------------MS-----------ET--ELR------------------KRQAQFTRELHGDDIGKKTG---------------------LSA-LMSKNNSAQ-----KEAVQKYLRNW-DGRT-------------DKD-------------------------------------------------------------------------AEE----RRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDYNEATHSY------YNVV----T--DF-YEYGW-----GS-----------------SFHFSR------------------------FY-K------GES-------------FAASIARHEHYLAYKAG-IQ-----------------RGDL-----------VLDVGCGVGGPAREIARFT-GCN--VIGLNN-NDYQIAKAKYYAKKY--N-------------------------LS-DQ----------------MDFVKGDF-MKMD--FE--ENTFDKVYAIEATCHAPKLEGVYSEIYKVLKPGGTFAVYEWVMTDK----------------YD---ENNPEHRKIAYEIEL--GDGIP----------KMFHVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [258]
lcl|Smo_SMT1_11_1_unnamed_protein_product                                    ------------------------------------------------------------------------------------M------------------------------------------VTWGLLGTGAAMAAAGLYWAMCVAGSAEQKGKRAVDLGGGSLSRGEVAG-------NYREYAAFF--------D--------K--P-------------------------------------------------------------------------QQI----AAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DKVPKLVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------AV-P------GVG-------------HREETQLHEKYVADLLE-LG-----------------PGQR-----------VLDAGCGVGGPMRTIAAHS-GSN--VVGITI-NDYQVARARSHNSKA--G-------------------------LS-KL----------------CEVICGDF-LHMP--FG--DDSFDAAYSIEATCHAPQLRDVYAEIYRVLKPGKLYVSYEWVTTCK----------------YQ---AQDPEHVKIIHEIEH--GNALP----------GLRSYKQVVEIAKEVGF---EVL-EDRDLAL-----PP--A-HPW--WTRL--------------------KMGRLAYYRNHVVI------------------------------------ALLSFLGIAPQGVFE-VHE----------------MLFK-----------------------------TAMYLTRG-------GETGIF---------------------------SPMHLLVCRKPLDGGDAATAATAAVASS--------------------------------------------------------------   [372]
'gi|68566013|sp|O82427|SMT2 ORYSA 24-methylenesterol C-methyltransferase 2 (24-sterol C-methyltransferase 2) (Sterol-C-methyltra'     ------------------------------------------------------------------------------------M------------------------------------------EAATMAWTAAGVGMALVYWFVWVMGAAEVKGKRAVDLKMGSITNDKVKD-------KYTQYWSFF--------R--------R--P-------------------------------------------------------------------------KETATTEASA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKVPAFVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------SL-P------GRS-------------HREATRVHEERVADLLQ-AK-----------------PGHR-----------LLDVGCGVGGPMRAIAAHS-GSN--VVGITI-NEYQVNRARAHNRKA--G-------------------------LD-SR----------------CEVVCGNF-LSMP--FS--DASFDGAYSIEATCHAPRLQDVYGEVFRVLKPGGLYVSYEWVTTSL----------------YR---ADNPEHVEAIHGIER--GDALP----------GLRRQDEIASIAKEVGF---EVL-KELDLAL-----PP--A-LPW--WTRL--------------------KMGRIAYWRNSLVV------------------------------------RVLTMLRIAPKGVCE-VHE----------------MLYE-----------------------------TAQHLTRG-------GETGIF---------------------------TPMHMVLLRKPVES-------------K--------------------------------------------------------------   [363]
'gi|3560533|gb|AAC34989.1| 24-methylene lophenol C24(1)methyltransferase [Oryza sativa]'                                    ------------------------------------------------------------------------------------M------------------------------------------EAATMAWTAAGVGMALVYWFVWVMGAAEVKGKRAVDLKMGSITNDKVKD-------KYTQYWSFF--------R--------R--P-------------------------------------------------------------------------KETATTEASA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKVPAFVDTF------YNLV----T--DI-YEWGW-----GQ-----------------SFHFSP------------------------SL-P------GRS-------------HREATRVHEERVADLLQ-AK-----------------PGHR-----------LLDVGCGVGGPMRAIAAHS-GSN--VVGITI-NEYQVNRARAHNRKA--G-------------------------LD-SR----------------CEVVCGNF-LSMP--FS--DASFDGAYSIEATCHAPRLQEVYGEVFRVLKPGGLYVSYEWVTTSL----------------YR---ADNPEHVEAIHGIER--GDALP----------GLRRQDEIASIAKEVGF---EVL-KEVDLAL-----PP--G-FPW--WTRL--------------------KMGRIAYWRNSLVV------------------------------------RVLTMLRIAPKGVCE-VHE----------------MLYE-----------------------------TAQHLTRG-------GETGIF---------------------------TPMHMVLLRKPVES-------------K--------------------------------------------------------------   [363]
'gi|62734689|gb|AAX96798.1| hypothetical protein LOC Os11g19140 [Oryza sativa (japonica cultivar-group)] >gi|77549992|gb|ABA9278'     ------------------------------------------------------------------------------------MAAASRPPHGRLSRGHLAPPPDRLPHGRRHPSTARAPAVRPATSVAAARPAAERRRIG------------------------------------------------------GGGEG--------NRRR-------------------------------------------------------------------------GEG----GGR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GDEGEEAVPV------FIAS----G--TI-VEFGR-----PT-----------------KDGFSTSVKMKQANVKYLKIHICMYFLRFIRW-H------GET-------------LRESLKRREHFLALQLG-LK-----------------KGMK-----------VLDVGCGIGGPLREIARFS-SAS--VTGLNN-NDYQISRGQELNFSV--G-------------------------LS-ET----------------CNYVKGDF-MNMP--IP--DCTFDAAYALDATCHAPDA-----------------------------------------------------------------------------------------------------VI-LAKDMAE------ES-P-LPW--YQPLDPSQLS----------LTHFQFTRIGRFLGQTLVSKQFITQTEATEFLACSWERLYSTIDFFLPAKNPQLKSLEFLHLAPEGSLR-ICR----------------FLAT-----------------------------SVDSLVKG-------GKEGIF---------------------------TPLFFVLARKPLQKQEEQI-----------------------------------------------------------------------   [371]
'gi|88185412|gb|EAQ92880.1| hypothetical protein CHGG 01115 [Chaetomium globosum CBS 148.51]'                                    ------------------------------------------------------------------------------------MTS--------------------------------------------------------------------------------HMPENYAED-------RLHRYLAHWTRDPSNVSKVDVAAISWATDE-------------------------------------------------------------------------ERR----ERQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKYYQVGSDY------YDLV----T--PL-YEQGW-----GQ-----------------QFHYTP------------------------IT-P------GLS-------------IRESMTAYEKTFAGLAR-LT-----------------KGMR-----------VLDLGCGIGGPARTIAAAI-GCS--IVGITN-NAWHVERGTALTKEA--G-------------------------MG-HL----------------VTLVDGDF-LKLP--FP--DESFDAAYSVESLCYAPDPAAVYREIKRVLKPGAPFMFHDFAMTEN----------------S----------------------------------------------------------------------------P-APW--YYGPAGDILWAWRMPGWPDFWKVFKMWEPFRGCAHLVY------------------------------------RAMIFVGKAPPEVST-LMD----------------TMWY-----------------------------CTKSVVIG-------GKMGIF---------------------------TPMYVFVCRKPGGEKK--------------------------------------------------------------------------   [310]
'gi|66820068|ref|XP 643680.1| hypothetical protein DDB0202574 [Dictyostelium discoideum] >gi|60471790|gb|EAL69745.1| hypothetica'     ------------------------------------------------------------------------------------MVLIQTNHQSKPIEINQSAEKVIAFLLDVPTVAKCYPFVDSVVKVNANTYKWTMQERKVGSIQMKATHIAKYTKVNATTVQWENMTGGNMSSYGKYTIVSTGANKCTLSAEANIETDIEIPKLLVGFARTMGNREMTHTWNAFLESIKKTVETGSIVKIAPQEDVVKDEKFEGVRLKEEKRV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ENYNTMVSDY------YDIV----T--ET-YQSGW-----GN-----------------HFHFAP------------------------FK-T-----DTEP-------------LETAVKRLEHSVADSAR-IT-----------------KDSL-----------VLDVGCGVGGPTLEICQYT-GCK--IRGLNI-NKKQVGIATQRAKDL--G-------------------------VS-DR----------------ASFDHGDA-MKMP--YP--DNTFDVVTFFESTCHMPDKQAFIKECYRVLKPGGRMSGSEWLQCEK---------------------PTEKDIVQFIEPICA--HHSVP----------HMGSLMSYRSMMESAGF---YVH-IAMDLTQ------EGNI-LRN--WEVLDN--------------------------------------------------------------------KTINTFKALPKGSVDPTIE----------------MMIS-----------------------------GAIALSEG-------ARAGAF---------------------------V-LGRFLSSKPNAAKL--------------------------------------------------------------------------   [462]
'gi|16950435|gb|AAD12813.2| Hypothetical protein H14E04.1 [Caenorhabditis elegans] >gi|25143945|ref|NP 497549.2| H14E04.1 [Caeno'     ------------------------------------------------------------------------------------MSINMNANFLKLLTHFRRHDLTNFKSEHDTLYEKALET--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GDHLEVTSHY------YSVM----S--TV-IDEYF-----GG-----------------NFHFVP------------------------------PKFEGQK-------------LEEALKSLHCHIAEKLE-LS-----------------ENVH-----------CLDIGCGIGGVMLDIADF--GAK--LTGVTI-APNEAEIGNEKFANM--G-------------------------IS-DR----------------CKIVAADC-QKMP--FE--DSTFDVAYAIYSLKYIPNLDKVMKEIQRVLKPGGKFIVYDLIKTND----------------YD---KDNKEHYKTLHHLEY--ACGMP----------SLHTQSEVEAAAEKWEM---PVV-ERENLEETYGNRAFHYC-FSA-----------------------------------------------------------SPMFMWLVSSPVIDHTIRMAEILRILPAGFKQFNRT----------------FLCG-----------------------------TVNSIVGG-------GRMGIL---------------------------SGADILLFEKKKI-----------------------------------------------------------------------------   [334]
'gi|39588832|emb|CAE69462.1| Hypothetical protein CBG15658 [Caenorhabditis briggsae]'                                    ------------------------------------------------------------------------------------MSINMNANFLKLLTHFRRHDLTNFKTEHDVLYKKALET--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GDHLEVTTHY------YSVM----S--KV-IDDYF-----GG-----------------NFHFVP------------------------------PKFDGQP-------------LEEALKSLHQHIAAKLE-LN-----------------ENVH-----------CLDIGCGIGGVMLDIADF--GAK--LTGVTI-APNEAEIGNEKFAAL--G-------------------------LS-NK----------------CKIVAADC-HKMP--FE--DSAFDVAYAIYSLKYIPNLEKVMEEIQRVLKPGGKFIVYDLIKTND----------------YD---KDNQLHFETLHHLEY--ACGMP----------SLHTQSEIEKSASRSGM---ALI-EQENLEETFGNRAFHYC-FSA-----------------------------------------------------------SPFFMWLVTSSVIDHTIRLAEIMRILPAGFKQFNRT----------------FLCG-----------------------------TVNSIVEG-------GRMGIL---------------------------SGADILVFEK--------------------------------------------------------------------------------   [331]
'gi|67522314|ref|XP 659218.1| hypothetical protein AN1614.2 [Aspergillus nidulans FGSC A4] >gi|40745578|gb|EAA64734.1| hypotheti'     ------------------------------------------------------------------------------------MTT--------LASHRSGRSSE--SSVDVVAAEKEKLSTVQLSQANLDA---LPDLRNSASPKRWKTFWKSFRYLQHLTSKQVDDFMASYIIYNLDWSDEKQMVETLGEDYQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKVGDCLQAY------YGVL----N--HL-CALGD-----VE-----------------KMYIPP------------------------FM-S-----SKAT-------------VRENQLLYEESIAHDIG-LK-----------------PGDR-----------VLDLGCGRGRVAAHMSQYS-GAQ--VTGLNI-DPNQVAQARSFNTRL--G-------------------------FESNS----------------FIVQDFNS-LPLP--FA--DDSFDAFYQIQALSLCKDLPALFREIYRVVKPGARISLLDWVSLPD----------------YD---PSNAEHAELMRRVKP--LIGAV----------GTPTPEILENALMEAGF---TVL-RSDNASVGGLQAPLIDK-VDL--YFRSMRQLI-----------------------------------------------------------------LGLVKAHMLPRHFKT-LIN----------------RLCL-----------------------------DGQAFVKM-------DKMRLV---------------------------TTSYRIIAQKQA------------------------------------------------------------------------------   [387]
'gi|85116637|ref|XP 965096.1| hypothetical protein [Neurospora crassa N150] >gi|32422515|ref|XP 331701.1| hypothetical protein ['     ------------------------------------------------------------------------------------MSVPLQN-----------RVSDSSDGIDRIAEEKQKLSVNAPPSTRKQDALGLDDADRQSTTNRFKTFRSAFKYIHHLTPKQVDDYMHSYVIYNLDWADEDAMVKELGPDYQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKVGECLKAY------YGII----N--HL-CAMGD-----VE-----------------KMYIPP------------------------HM-D-----KRAS-------------VIENQLLYEKAVAHAIG-MK-----------------AGDK-----------VLDLGCGRGRVAAHMASMT-GAT--VTGLNI-DPNQVAQAQEFNNLK--G-------------------------FK-NT----------------FVQQDMNT-LPLP--FA--DNSFDCFYQIQALSLCKDLPTLFREVYRVLKPGAKVSLLDWVSLPG----------------YD---PSNPEHLALMRRVKP--LIGAV----------GTPTPKSFEKALEDAGF---VVT-KSENASIDGLQAPLIDR-VDI--YFRTMRQII-----------------------------------------------------------------LGLVKIKVLPQHFKT-LIN----------------RLCL-----------------------------DGQAFVKM-------DRMRLI---------------------------STSYWIVAEKPL------------------------------------------------------------------------------   [388]
'gi|2792343|gb|AAC01738.1| C-27 O-methyltransferase [Amycolatopsis mediterranei]'                                    ------------------------------------------------------------------------------------MT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPTPNEIGKG------YDAF----A--DL-LDQFW-----GE-----------------NLHHGY------------------------W--D--------DESAT---------LEEATTRLTDRLAGMLP-LR-----------------AGDR-----------LLDIGCGNGEPAIRMATAN-DVM--VTGISI-SEKQVERANDRAYKA--D-------------------------VD-DR----------------VVFEYADA-MELP--YP--DASFDVVWALESLHHMPDRWHVIRQAARVLRPGGRLALGDFLLVPS----------------------PAGLEADAERVREV--GKGVV----------AVVSLDEYQAHLREAGL---EPE-SAEDVSQ--------YT-RPS--WTKAAERFE----------------------------------------------------------------------------------------------------------------------------------------------------GLREQALQHIEA--AQFEVTLGRFRAFSEEPS-LGYVLLTARKPD------------------------------------------------------------------------------   [272]
'gi|83769009|dbj|BAE59146.1| unnamed protein product [Aspergillus oryzae]'                                    ------------------------------------------------------------------------------------MTETQTV----LASRQSGRSSE-SSSLDAIAAEKQNLAVHSVPST-------RPDLHNSASPKRWKTFWTAFRYLQHLTPKQVDDFMASYVIYNLDWSDEKQMVEELGPNYQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKVGDCLKSY------YGVL----N--HL-CALGD-----VE-----------------KMYIPP------------------------FM-S-----KKAT-------------VLENQLLYEESIAEHIG-LK-----------------PGDK-----------VLDLGCGRGRVAAHMTQYS-GAH--VTGLNI-DPNQIAQARSYNEKL--G-------------------------FKDNR----------------FIVQDFNS-LPLP--FE--DETFDAFYQIQAFSLCKDLPALFREIFRVLKPGARFSMLDWVSLPD----------------YD---PSNPEHVQLMRRVKP--LIGAV----------GTPTPKILENALTDAGF---TVT-RSDNASVGGLQAPLIAK-VDL--YFRSMRQLI-----------------------------------------------------------------LGLVKTHVLPKHFKT-LIN----------------RLCL-----------------------------DGEAFVKM-------DNMRLV---------------------------TTSYRIIAQKPLH-----------------------------------------------------------------------------   [389]
'gi|67925248|ref|ZP 00518612.1| similar to Methylase involved in ubiquinone/menaquinone biosynthesis [Crocosphaera watsonii WH 8'     ------------------------------------------------------------------------------------M---------------------------------------------------------------------------------------------------------------------------------------------------------------------TNT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNLSEKIAKF------YDTS------SNL-WEKTW-----GE-----------------HMHHGY------------------------YG-R------GGN-----YK--LD--RRQAQINLIEELLIWAD-IK-----------------EVSN-----------LVDVGCGIGGSTLYLAERF-NTK--ATGITL-SSVQANRATERASEF--K-------------------------LE-ET----------------VQFQVADA-LNMP--FP--EDNFDLVWSLESGEHMPDKKKFFQECYRVLKPGGTFLCVTWCHRPT----------------NSWAGELTEEEKQHLEEIYR--VYCLP----------YVLSLPEYETIAQDCGF---SNI-KIDDWSM--------EV-APF--WDIVIDSAL--NLETIAGLLNSGWQTVQGALSLGLMSR-----------------------------------------------------------------------------------------------------------------------GYERGL---------------------------IRFGLIYGQK--------------------------------------------------------------------------------   [284]
'gi|70994118|ref|XP 751906.1| S-adenosyl-methionine-sterol-C- methyltransferas [Aspergillus fumigatus Af293] >gi|66849540|gb|EAL'     ------------------------------------------------------------------------------------MMETQTTAPALASSRQCGRSSESSSSVDVIAQEKQKVAAAAASSKTSTASKDRPDLHNSASPKRWKTFWAAFRYLQHLTPKQVDDFMASYVIYNLDWSDEKQMIETLGPNYQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKVGDCLKAY------YGVL----N--HL-CALGD-----VE-----------------KMYIPP------------------------FM-S-----KKAT-------------VLENQLLYEESIARDIG-LG-----------------PGDK-----------VLDLGCGRGRVAAHMTQFSGGAQ--VTGINI-DPNQVAQAQKFNDKR--G-------------------------FQ-NK----------------FVVQDFNS-LPLP--FE--DESFDAFYQIQALSLCKDLTALFREIYRVVKPGAKISLLDWVSLPA----------------YD---PSNPEHAELMRRVKP--LIGAV----------GTPTPEILERALVDAGF---TVL-RSDNASLDGLQAPLIDT-VDF--YFRSMRQVI-----------------------------------------------------------------LGLVKVHALPYHFKT-LIN----------------RLCL-----------------------------DGQAFVKM-------DRMRLC---------------------------STSYRIIAQKPSR-----------------------------------------------------------------------------   [401]
'gi|75704727|gb|ABA24403.1| Cyclopropane-fatty-acyl-phospholipid synthase [Anabaena variabilis ATCC 29413] >gi|75911002|ref|YP 3'     ------------------------------------------------------------------------------------M-----------------------------------------------------------------------------------------------------------------------------------------------------------------------S---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATLYQQIQQF------YDAS------SGL-WEEIW-----GE-----------------HMHHGY------------------------YG-V------DGT-----EQ--KN--RRQAQIDLIEELLTWAG-VQ-----------------TAEN-----------ILDVGCGIGGSSLYLAEKL-NAK--ATGITL-SPVQAARATERAKEA--G-------------------------LS-GR----------------SQFLVANA-QAMP--FD--DNSFDLVWSLESGEHMPDKTKFLQECYRVLKPGGKLIMVTWCHRPT----------------D--ETPLTADEQKHLEDIYR--VYCLP----------YVISLPEYEAIARQLPL---NNI-RTADWSQ--------SV-AQF--WNIVIDSAF--TPQAIFGLLRAGWTTIQGALSLGLMRR-----------------------------------------------------------------------------------------------------------------------GYERGL---------------------------IRFGLLCGDK--------------------------------------------------------------------------------   [280]
'gi|85816299|gb|ABC84455.1| NigE [Streptomyces violaceusniger]'                                    ------------------------------------------------------------------------------------MTSPSA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPPGDTVSDY------YSSL----G--PL-LQMAW-----DD-----------------NFHFGY------------------------W--D------GPSDTSS---------VQEATDRFTDLLIERLR-VG-----------------PGDR-----------VLDVGCGIGKPAMRVATST-GAD--VLGITI-SELQVKQAAESARLA--G-------------------------LS-DR----------------VAFQYADA-MAMP--FE--GAAFDAVLAFESINHM-DRPTALREMARVLRPGGRLVLTDVTPPSD----------------------------GSYRPDGD--PGVVT----------SLTRLEDWPRLVDEAGL---VLD-ELTDVTE--------NT-KDT--ANRMIDGIL----------------------------------------------------------------------------------------------------------------------------------------------------RCRREFEARHGV--SVQEVLDAAKSALPTVPS-AGCAIVVAHKS-------------------------------------------------------------------------------   [270]
'gi|17130893|dbj|BAB73502.1| gamma-tocopherol methyltransferase [Nostoc sp. PCC 7120] >gi|17229295|ref|NP 485843.1| gamma-tocoph'     ------------------------------------------------------------------------------------M-----------------------------------------------------------------------------------------------------------------------------------------------------------------------S---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATLYQQIQQF------YDAS------SGL-WEEIW-----GE-----------------HMHHGY------------------------YG-A------DGT-----EQ--KN--RRQAQIDLIEELLTWAG-VQ-----------------TAEN-----------ILDVGCGIGGSSLYLAGKL-NAK--ATGITL-SPVQAARATERAKEA--G-------------------------LS-GR----------------SQFLVANA-QAMP--FD--DNSFDLVWSLESGEHMPDKTKFLQECYRVLKPGGKLIMVTWCHRPT----------------D--KTPLTADEKKHLEDIYR--VYCLP----------YVISLPEYEAIARQLPL---NNI-RTADWSQ--------SV-AQF--WNIVIDSAF--TPQAIFGLLRAGWTTIQGALSLGLMRR-----------------------------------------------------------------------------------------------------------------------GYERGL---------------------------IRFGLLCGDK--------------------------------------------------------------------------------   [280]
'gi|86555433|gb|ABD00391.1| cyclopropane-fatty-acyl-phospholipid synthase family protein [Synechococcus sp. JA-3-3Ab] >gi|866068'     ------------------------------------------------------------------------------------M-----------------------------------------------------------------------------------------------------------------------------------------------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPLNQRIRRF------YDAS------SGL-WEQVW-----GE-----------------HMHHGY------------------------YE-P------GQT--------GKD--RRQAQIDLIDRVIQWGQ-IG--------------DPKPPRH-----------ILDLGCGIGGSSLELARRF-GAE--VTGITL-SPVQAQRAEERAQAA--G-------------------------LS-NR----------------VRFWVADA-LDMP--FA--DNTFDLVWALESGEHMPDKRRFLAECWRVLQPGGQMMVVTWCHR---------------------EGSLSRQDERLLQQIYD--VYCLP----------YVISLSEYEALAHQVGF---ERL-RTADWSE--------RV-APF--WDEVIASAR--DWRWIPALLRSGWVTVRGALGLGLMRR-----------------------------------------------------------------------------------------------------------------------AYASGL---------------------------LRFGLLSGFKPAS-----------------------------------------------------------------------------   [282]
'gi|4731342|gb|AAD28459.1| MitM [Streptomyces lavendulae]'                                    ------------------------------------------------------------------------------------MPHSELSELPMP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPASEEVGAL------YDRF----T--AL-GAASL-----GE-----------------NLHFGY------------------------W--D------SPDSQVP---------LAEATDRLTDMMAERLR-IG-----------------AGSR-----------VLDLGCGVGTPGVRIARLS-GAH--VTGISV-SHEQVVRANALAEEA--G-------------------------LA-DR----------------ARFQRADA-MDLP--FE--DESFDAVIALESIIHMPDRAQVLAQVGRVLRPGGRLVLTDFFERAP----------------------LAPEGRAAVQRYLH--DFMM-----------TMVSAEAYPPLLRGAGL---WLE-EFLDISD--------QTLEKT--FRLLSERIN----------------------------------------------------------------------------------------------------------------------------------------------------SSKQRLETQFGE--EMVNQFDPG--DLVGVKE-FGYLLLVAQRPGK-----------------------------------------------------------------------------   [283]
lcl|Smo_SMT1_17_1_unnamed_protein_product                                    ------------------------------------------------------------------------------------MASS-------------------------------------CPGAATAHSCSSRPTPWLWGFRSMPLSQHKISAAGSDSTGAAMT--------------------------------------------------------------------------AVTSKGPPVP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EELNRGIARF------YDSS------SSV-WEDVW-----GE-----------------HMHHGF------------------------YD-P------GKP-----LK--GD--HRAAQVRMIEEALAWAG-IP-------------ADEEKPKK-----------IVDVGCGIGGSARHLSRKY-SAM--VRGITL-SPVQAQRANNITAEA--G-------------------------LG-EK----------------VSFQVADA-LNQP--FP--DNEFDLVWSMESGEHMPDKRKFMQELVRVAAPGGRLLIVTWCHRDL----------------SPEESSLRKEEQELLDKICS--AYYLP----------AWCSAFDYVELAKELQL---EDV-RAEDWSV--------YV-SPF--WPAVIASAL--NPKALFGLLRSGWTTIRGAFAMTS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [323]
'gi|35213660|dbj|BAC91031.1| gamma-tocopherol methyltransferase [Gloeobacter violaceus PCC 7421] >gi|37522659|ref|NP 926036.1| g'     ------------------------------------------------------------------------------------M---------------------------------------------------------------------------------------------------------------------------------------------------------------------GER---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVLNENIRRF------YDAS------SGL-WEEVW-----GE-----------------HMHHGH------------------------WE-V------GEA--------DKD--RRVAQVDLVVRLLDWAG-ID-----------------RAES-----------IVDVGCGIGGSSLFLAERF-GAR--VEGITL-SPVQCKRAAERAREH--H-------------------------LD-GR----------------AHFQVADA-HRMP--FA--DGRFDLVWSLESGEHMADKAQFLRECHRVLRPGGRFVFVTWCCR---------------------HGALDARDQKWLGAIYR--IYHLP----------YILSIESYTQLLGETGF---SGI-RTTDWSD--------RV-ARF--WSLVIDSAL--EPAVLWKVIAQGPTVIKGALAMQLMRR-----------------------------------------------------------------------------------------------------------------------SYARGL---------------------------VRFGVFAAQKAEG-----------------------------------------------------------------------------   [281]
'gi|75914741|gb|ABA29783.1| MmxM [Cystobacter fuscus]'                                    ------------------------------------------------------------------------------------MSEV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYTAEGVGRY------YDAM----A--QF-YQTVW-----GD-----------------SIHMGF------------------------WP-D------PTDATVS---------MSQAQKNFTDLMISHMG-LQ-----------------PGQR-----------ALDVGCGTGRPAIQLARAT-HTH--VTAISI-SQSQIATATGYARES--G-------------------------VA-PRAQVQGTDDAPS-----VRFELADA-MAMP--FR--DGTFDAAWAFESIFHMPSRLQVFREMARVVRPGGRVVVADFVTLRP----------------------LTPEERAIAYP-----AFAAN----------DLASLEDYIRDLKQVGL---TNI-NCRDVTA--------NTFRPS--NRATARELQTE--------------------------------------------------------------------------------------------------------------------------------------------------AAQAHLRNAYGH--EQADSFRNGWVHIEKVNETLGYVLIQADKP-------------------------------------------------------------------------------   [288]
'gi|30795000|ref|NP 851450.1| putative NDP-hexose 3-O-methyltransferase [Streptomyces rochei] >gi|30698373|dbj|BAC76486.1| putat'     ------------------------------------------------------------------------------------MTSGAQAPE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DRVEDKVVDF------YDNF----T--EV-FREIW-----GD-----------------NLHVGY------------------------W--H------DDADDAP---------IEKATDQLTDQLIARLA-PA-----------------PGQR-----------ILDVGCGVGEPAFRLARTA-DVE--VVGVSI-SAYQVGRAGERARDF--G-------------------------LA-DR----------------VSFRHADA-AELP--FP--DASFDGGWAFESLIHMPDKEKVLREIKRVLRPGATLVLADMFSQPD----------------------TELTFQDII----------------------TTPEMADYRAVIESAGL---VVR-EFTDITA--------HTLAPPAVRESVAADLL----------------------------------------------------------------------------------------------------------------------------------------------------ARKDDVIAMTGP--EEFARMVDGVRVPKA----YGYLLATVTTD-------------------------------------------------------------------------------   [270]
lcl|Smo_SMT1_14_1_unnamed_protein_product                                    ------------------------------------------------------------------------------------MASS-------------------------------------CPGAATAHSCSSRPTPWLWGFRSMPLSQHKISASGSDSTGAAMA--------------------------------------------------------------------------AVASKGPPVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EELNRGIARF------YDSS------SSV-WEDVW-----GE-----------------HMHHGF------------------------YD-P------GKP-----LK--GD--HRAAQVRMIQEALAWAG-IP-------------ADEEKPKK-----------IVDVGCGIGGSARHLSRKY-SAM--VRGITL-SPVQAQRANDITAEA--G-------------------------LG-EK----------------VSFQVADA-LIQP--FP--DNEFDLVWSMESGEHMPDKRKFMQELVRVAAPGGRLLIVTWCHRDL----------------SPEESSLRKEEQELLDKICS--AYYLP----------AWCSAFDYVELAKELQL---EDV-RAEDWSV--------YV-SPF--WPAVIASAL--NPKALFGLLRSGWTTIRGAFAMAYMIQ-----------------------------------------------------------------------------------------------------------------------GYKSGL---------------------------IKFAVITGRKPVA?----------------------------------------------------------------------------   [346]
'gi|86553437|gb|ABC98395.1| cyclopropane-fatty-acyl-phospholipid synthase family protein [Synechococcus sp. JA-3-3Ab] >gi|866048'     ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNPTLWVFWGLVLLLAIGLGA-------------------------------------------------------------------------------------------------YLLTARK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YRSPESVARA------YDEW----TRDGI-LEFYW-----GE-----------------HIHLGH------------------------Y--G------SPP-----RR--KN--FIQAKHDFVHEMVRWGG-LD--------------RLPPGTT-----------VLDVGCGIGGSCRILARDY-GFV--VTGITI-SPQQVQRAQELTPPD-------------------------------LP----------------VRFQVADA-LNLP--FP--DASFDVVWSIEAGPHMPDKARYASEMLRVLKPGGILVVADWNQRDD----------------R--QKPLNFWERLVMRQLLD--QWSHP----------AFSSIEGFAEQLQATGLVE-GQV-QTADWTQ--------ET-LPS--WLDSIWQGVVRPEGLLKFGLVGLIKSLREVPTFLLMRL-----------------------------------------------------------------------------------------------------------------------AFGTGL---------------------------CRFGMFRAVRAATPANSARPEVVAHSTQH-------------------------------------------------------------   [330]
'gi|71673845|ref|ZP 00671593.1| similar to Cyclopropane fatty acid synthase and related methyltransferases [Trichodesmium erythr'     ------------------------------------------------------------------------------------M-----------------------------------------------------------------------------------------------------------------------------------------------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STLIEKIQKF------YDAS------SSL-WEQAW-----GE-----------------HMHHGY------------------------YG-P------DGK-----QK--KT--RRQAQIDMIEELLHWGS-EN-----------QASSLWPPTS-----------ILDVGCGIGGSTLYLAEKF-NAT--ATGITL-SPVQAKRAEERAESA--N-------------------------LS-QQ----------------TNFIVADA-LDMP--FT--DQSYDLVWSLESGEHMPNKKKFLQECHRVLKPGGRIIMATWCHRTL----------------DGYLGQLTDDERRHLADIYR--VYALP----------YVISLSEYEAIAENISF---QNI-SIADWST--------AV-APF--WDVVIESAF--DPKVIVSLLFSNWTTIQAAISLELMSR-----------------------------------------------------------------------------------------------------------------------GYERGL---------------------------IKFGLLRGNKQLINT---------------------------------------------------------------------------   [293]
'gi|23128517|ref|ZP 00110362.1| COG0500: SAM-dependent methyltransferases [Nostoc punctiforme PCC 73102]'                             ------------------------------------------------------------------------------------M-----------------------------------------------------------------------------------------------------------------------------------------------------------------------S---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATLYQQIQQF------YDAS------SGL-WEQIW-----GE-----------------HMHHGY------------------------YG-A------DGT-----QK--KD--RRQAQIDLIEELLNWAG-VQ-----------------AAED-----------ILDVGCGIGGSSLYLAQKF-NAK--ATGITL-SPVQAARATERALEA--N-------------------------LS-LR----------------TQFQVANA-QAMP--FA--DDSFDLVWSLESGEHMPDKTKFLQECYRVLKPGGKLIMVTWCHRPT----------------D--ESPLTADEEKHLQDIYR--VYCLP----------YVISLPEYEAIAHQLPL---HNI-RTADWST--------AV-APF--WNVVIDSAF--TPQALWGLLNAGWTTIQGALSLGLMRR-----------------------------------------------------------------------------------------------------------------------GYERGL---------------------------IRFGLLCGNK--------------------------------------------------------------------------------   [280]
'gi|53756460|gb|AAU90751.1| methyltransferase, UbiE/COQ5 family [Methylococcus capsulatus str. Bath] >gi|53802699|ref|YP 112622.'     ------------------------------------------------------------------------------------MYYLEPNKDYRNDSLRKGAEFSE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEIRIDTARH------YDDC-------YWDYRTAW-----FD-------------NENLALHYGY------------------------WE-E------------------GIKTHSQALINKNRIMAAIAG-IE-----------------AGDH-----------VLDAGCGIGGSSIWLAKHV-GAR--ATGITV-SEQQVEHARRNARRH--G-------------------------VA-DK----------------TEFQVADF-CQTP--FP--DAVFDVVWAVESSCYATDKRDFFREAYRVLKPGGTLIACDGYAARR---------------------EFDEAEWRAVMDCLN--GWAVP----------NLSTVEEFHAGMEECGF---REI-HVTEATR--------ET-LPS--SRRMYLTARWTAPMQWIMHWLGLRKKAQTANYKVALAQWK---------------------------------------------------------------------------------------------------------------------VFSEGM---------------------------VRYCIFRAEKPV------------------------------------------------------------------------------   [305]
'gi|86556997|gb|ABD01954.1| cyclopropane-fatty-acyl-phospholipid synthase family protein [Synechococcus sp. JA-2-3B''a(2-13)] >gi'    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVDPMNPIFWALGIAVLLAVGLAA-------------------------------------------------------------------------------------------------YLLTARK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YESPASVAKS------YDEW----TRDGI-LEFYW-----GE-----------------HIHLGH------------------------Y--G------SPP-----QR--KN--FLQAKHDFVHEMVRWGG-LD--------------RLPAGTT-----------VLDVGCGIGGSCRILARDY-GFV--VTGITI-SPQQVKRAQELTPPD-------------------------------LP----------------VQFQVADA-LDLP--FP--DASFDVVWSIEAGPHMPDKARYAQEMLRVLKPGGILVVADWNQRDD----------------R--QKPLNFWERLVMRQLLD--QWSHP----------SFSSIEGFAEQLEATGLVA-GRV-ETADWTQ--------ET-LPS--WLDSIWQGIVRPEGLLKFGLVGLIKSLREVPTFLLMRL-----------------------------------------------------------------------------------------------------------------------AFGTGL---------------------------CRFGMFRAVRAATSADSTRTEVVAHSSQ--------------------------------------------------------------   [332]
'gi|86558383|gb|ABD03340.1| cyclopropane-fatty-acyl-phospholipid synthase family protein [Synechococcus sp. JA-2-3B''a(2-13)] >gi'    ------------------------------------------------------------------------------------M-----------------------------------------------------------------------------------------------------------------------------------------------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STLNQRIRHF------YDAS------SGL-WERVW-----GE-----------------HMHHGY------------------------YE-P------GQT--------GKD--RRQAQIDLIDRVIQWGQ-IG--------------DPCPPQH-----------ILDLGCGIGGSSLELAQRF-GAQ--VTGITL-SPVQAKRAGERAQEA--G-------------------------LS-SM----------------VQFQVADA-LEMP--FA--ADTFDLVWSLESGEHMPDKQRFLAECWRVLQPGGQLMVVTWCHR---------------------EGSLSRQDQQLLQKIYE--VYCLP----------YVISLSGYEVLAQQVGF---EQV-RSADWSE--------RV-APF--WDEVIASAR--DWRWIWALLRSGWVTVRGALGLGLMRQ-----------------------------------------------------------------------------------------------------------------------AYATGL---------------------------LRFGLLTGFKPGDQPR--------------------------------------------------------------------------   [285]
'gi|22535505|dbj|BAC10678.1| putative D-glucose O-methyltransferase [Lechevalieria aerocolonigenes]'                                  ------------------------------------------------------------------------------------MTESKSEGTAVA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APTPEEVRQM------YDDF----T--DP-FARIW-----GE-----------------NLHFGY------------------------W--E------DAGADVS---------VDDATDRLTDEMIALLD-VR-----------------SGDR-----------VLDVGCGIGKPAVRLATAR-DVR--VTGISI-SRPQVNQANARATAA--G-------------------------LA-NR----------------VTFSYADA-MDLP--FE--DASFDAVWALESLHHMPDRGRALREMARVLRPGGTVAIADFVLLAP----------------------VEGAKKEAVDAFRA--GGGVL----------SLGGIDEYESDVRQAEL---VVT-STVDISA--------QA-RPS--LVKTAEAFE----------------------------------------------------------------------------------------------------------------------------------------------------NARSQVEPFMGA--EGLDRMIATFRGLAEVPE-AGYVLIGARKP-------------------------------------------------------------------------------   [283]
'gi|22536129|gb|AAN01212.1| methyltransferase [Lechevalieria aerocolonigenes] >gi|22830829|dbj|BAC15754.1| RebM [Lechevalieria a'     ------------------------------------------------------------------------------------MA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APTPEEVRQM------YDDF----T--DP-FARIW-----GE-----------------NLHFGY------------------------W--E------DAGADVS---------VDDATDRLTDEMIALLD-VR-----------------SGDR-----------VLDVGCGIGKPAVRLATAR-DVR--VTGISI-SRPQVNQANARATAA--G-------------------------LA-NR----------------VTFSYADA-MDLP--FE--DASFDAVWALESLHHMPDRGRALREMARVLRPGGTVAIADFVLLAP----------------------VEGAKKEAVDAFRA--GGGVL----------SLGGIDEYESDVRQAEL---VVT-STVDISA--------QA-RPS--LVKTAEAFE----------------------------------------------------------------------------------------------------------------------------------------------------NARSQVEPFMGA--EGLDRMIATFRGLAEVPE-AGYVLIGARKP-------------------------------------------------------------------------------   [273]
lcl|7580_Cre_unnamed_protein_product                                    ------------------------------------------------------------------------------------MLGQSLRGDVGRSASVRSSQPTASIAPISSRSASRRVACASAQSTDVASEAVATTSAGAARSAAREVYQLSDAACCSTSAPTASTTFAGVDPTVLAAVAGLGLSLFALKRILDTPS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKYDNNVGQE------YDAW----TEEGV-LEYYW-----GE-----------------HIHLGY------------------------Y--S------DEELARGYLK--KD--FKQAKFDFVDEMLRFSG-AK-----------------NPAT-----------ILDVGCGFGGTSRHLAKKFRDAN--VTGITL-SPKQVQRGTELAKEQ--G-------------------------VG-N-----------------VKFQVMDA-LAME--FP--DNSFDLVWACESGEHMPDKRKYIEEMTRVLKPGGTLVIACWCQREE----------------G--DKPFTPQDKEDLQFLYD--EWAHP----------YFISIAEFGRLMNGTGKL--DGV-KLEDWNK--------NT-ISS--WRHSIWVGVFDPWVVVFKGPRIWYKTVREIVTLERMHQ-----------------------------------------------------------------------------------------------------------------------AFEKGL---------------------------MEYGMMTATKKLAPASESAANTQDRVPVGAKA----------------------------------------------------------   [425]
'gi|1653572|dbj|BAA18485.1| sterol-C-methyltransferase [Synechocystis sp. PCC 6803] >gi|16331079|ref|NP 441807.1| sterol-C-methy'     --------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPEYLLLPAGLISLSLAIAAGL-------------------------------------------------------------------------------------------------YLLTARG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQSSDSVANA------YDQW----TEDGI-LEYYW-----GD-----------------HIHLGH------------------------Y--G------DPP-----VA--KD--FIQSKIDFVHAMAQWGG-LD--------------TLPPGTT-----------VLDVGCGIGGSSRILAKDY-GFN--VTGITI-SPQQVKRATELTPPD-------------------------------VT----------------AKFAVDDA-MALS--FP--DGSFDVVWSVEAGPHMPDKAVFAKELLRVVKPGGILVVADWNQRDD----------------R--QVPLNFWEKPVMRQLLD--QWSHP----------AFASIEGFAENLEATGLVE-GQV-TTADWTV--------PT-LPA--WLDTIWQGIIRPQGWLQYGIRGFIKSVREVPTILLMRL-----------------------------------------------------------------------------------------------------------------------AFGVGL---------------------------CRFGMFKAVRKNATQA--------------------------------------------------------------------------   [318]
'gi|17131212|dbj|BAB73820.1| all2121 [Nostoc sp. PCC 7120] >gi|17229613|ref|NP 486161.1| hypothetical protein all2121 [Nostoc sp'     ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSWLFSTLVFFLTLLTAGIAL-------------------------------------------------------------------------------------------------YLITARR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQSSNSVANS------YDQW----TEDGI-LEFYW-----GE-----------------HIHLGH------------------------Y--G------SPP-----QR--KD--FLVAKSDFVHEMVRWGG-LD--------------KLPPGTT-----------LLDVGCGIGGSSRILARDY-GFA--VTGITI-SPQQVQRAQELTPQE-------------------------------LN----------------AQFLVDDA-MALS--FP--DNSFDVVWSIEAGPHMPDKAIFAKELMRVLKPGGIMVLADWNQRDD----------------R--QKPLNFWEKPVMQQLLD--QWSHP----------AFSSIEGFSELLAATGLVE-GEV-ITADWTK--------QT-LPS--WLDSIWQGIVRPEGLVRFGLSGFIKSLREVPTLLLMRL-----------------------------------------------------------------------------------------------------------------------AFGTGL---------------------------CRFGMFRALRADTVRSSAEQTSAIKVAQK-------------------------------------------------------------   [330]
'gi|33943786|gb|AAQ55554.1| MPBQ/MSBQ transferase cyanobacterial type [Chlamydomonas reinhardtii]'                                    ------------------------------------------------------------------------------------MLGQSLRGDVGRSASVRSSQPTASIAPISSRSASRRVACASAQSTDVASEAVATTSAGAARSAAREVYQLSDAACCSTSAPTASTTFAGVDPTVLAAVAGLGLSLFALKRILDTPS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKYDNNVGQE------YDAW----TEEGV-LEYYW-----GE-----------------HIHLGY------------------------Y--S------DEELARGYLK--KD--FKQAKFDFVDEMLRFSG-AK-----------------NPAT-----------ILDVGCGFGGTSRHLAKKFRDAN--VTGITL-SPKQVQRGTELAKEQ--G-------------------------VG-N-----------------VKFQVMDA-LAME--FP--DNSFDLVWACESGEHMPDKRKYIEEMTRVLKPGGTLVIACWCQREE----------------G--DKPFTPQDKEDLQFLYD--EWAHP----------YFISIAEFGRLMNGTGKL--DGV-KLEDWNK--------NT-ISS--WRHSIWVGVFDPWVVVFKGPRIWYKTVREIVTLERMHQ-----------------------------------------------------------------------------------------------------------------------AFEKGL---------------------------MEYGMMTATKKLAPASESAANTQDRVPVGAKA----------------------------------------------------------   [425]
'gi|33633451|emb|CAE08656.1| probable sterol-C-methyltransferase [Synechococcus sp. WH 8102] >gi|33866673|ref|NP 898232.1| proba'     ------------------------------------------------------------------------------------M-----LAGL------------------------------------------------------------------------------------LLLTGAAGATALLI-------------------------------------------------------------------------------------------------WLQRDRR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHSSDSVAAA------YDAW----TDDQL-LERLW-----GD-----------------HVHLGH------------------------Y--G------NPP-----GS--VD--FRQAKEAFVHELVRWSG-LD--------------QLPRGSR-----------VLDVGCGIGGSARILARDY-GLD--VLGVSI-SPAQIRRATELTPAG-------------------------------LS----------------CRFEVMDA-LNLQ--LP--DRQFDAVWTVEAGPHMPDKQRFADELLRVLRPGGCLAAADWNRRAP----------------K--DGAMNSTERWVMRQLLN--QWAHP----------EFASISGFRANLEASPHQR-GLI-STGDWTL--------AT-LPS--WFDSIAEGLRRPWAVLGLGPKAVLQGLRETPTLLLMHW-----------------------------------------------------------------------------------------------------------------------AFATGL---------------------------MQFGVFRLSR--------------------------------------------------------------------------------   [309]
'gnl|CMER|CMT560C probable delta(24)-sterol C-methyltransferase'                                    MHQLAFAHAWAVPKSHAPGKRGGLLRFTDDRLSRFATHRLRCWNHRRITRLAGYAQRRSSCVSAVEYGAPLLQTELVAQSVLSTANRASVRVPA------------------TERTINERLSWNTLSTWTQNARERLRVHPGRALSIAAITILAIATLYRFIMARRRTEYLLKRKALGLDTTPAAAGPQWRL---------------------------------------------------PGDETKATES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGLAQRIATF------YDLQ------SEL-WEQVW-----GE-----------------HMHHGF------------------------YN-V------DGT-----RDG-KD--DRQAQIDMMDRLLHYSG-VD------ASIRSAIGAGHRRLR-----------VLDVGCGIGGASRYIALRY-GADVHVTGVTL-SPVQASRAQVLTRQL--R-------------------------LE-DR----------------VETVVADA-LALP--FP--DNAFDVIWSMESAEHMPNKFRFMEECARVLRPGGILAMTAWCHRRC----------------PP---PFTDADRRIYRKVCA--YYCIP----------FLCTLDEFENYAWQCGL---VDI-ETADWTR--------AT-LPF--WPAVARSAL--QRKALLGLVEGGWPVIRSALAIRWMIR-----------------------------------------------------------------------------------------------------------------------GFRRNL---------------------------FVIGALRAVKPAPR----------------------------------------------------------------------------   [479]
'gi|48855417|ref|ZP 00309576.1| COG0500: SAM-dependent methyltransferases [Cytophaga hutchinsonii]'                                   ------------------------------------------------------------------------------------MGIRNSK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TFTSTDIATY------YDVS----E--DH-YMYFW------------------DLNQSHSLHYGY------------------------WD-A------------------STKTFREALANINRVLAEKAS-IT-----------------AGTR-----------VLDAGCGVGGSSIWLAKNK-QAN--VTGITV-SKKQAARANTSAAAV--N-------------------------PG-GT----------------AVFDVQDY-TNTP--YH--SESFDVVWAIESVCHAANKEDFIKEAYRLLKPGGQLIMADFFIVKD----------------------GNADDQRSIDAWGH--GWAVP----------FFEKKDAFQHMLLKAGF---NTA-DMIDSTE--------HI-RRS--AKRLYY---------------------------------------------------------------------------------------AFFPGWIISKLYNLVNRRTT-----------------------------EFSKNNVYTAYYQYKTLKKEL---------------------------WKYYIVHAKK--------------------------------------------------------------------------------   [287]
'gi|38260034|gb|AAR15334.1| C5-O-methyltransferase [Streptomyces griseochromogenes]'                                    ------------------------------------------------------------------------------------MITTSQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SISPDHVADY------YDRL----T--DL-FGEAA-----DG-----------------NLHFGY------------------------W--P------HPHDGSS---------LGVAADRLTDHLIGKLG-DI-----------------AGRR-----------VLDVGCGSGKPAVRLALSA-PTE--VVGVTV-SPVQVERATALAERE--G-------------------------VA-DR----------------VRFVCADA-MTLP--FP--DASFDAVWALECMFHMPSPAQVLGEISRVLCPGGRLAVMDVVLREP----------------------VPALDRGAVERGRL--MFAVP----------AHIELAEYPRLILGAGL---RLE-EMADLGD--------EIIRPS--TEALGRAAT----------------------------------------------------------------------------------------------------------------------------------------------------ANPAAFAAAFGVDTERFDTLVAEWAQITAALN-LGYVVLTAKRPE------------------------------------------------------------------------------   [281]
'gi|22295452|dbj|BAC09278.1| delta(24)-sterol C-methyltransferase [Thermosynechococcus elongatus BP-1] >gi|22299269|ref|NP 68251'     --------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHLGLILVITVVALVLLGLAL-------------------------------------------------------------------------------------------------YLLFPRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YESARSVAES------YDNW----TKDGI-LEFYW-----GE-----------------HIHLGH------------------------Y--G------LPP-----RP--KD--FRQAKVDFVHEMVRWAG-LD--------------RLPPGTT-----------VLDVGCGIGGSSRILARDY-GFH--VTGITI-SPEQVRRARELTPAE-------------------------------LN----------------VRFQLDDA-LALS--FP--DASFDVVWSIEAGPHMPDKQQFAKELLRVLKPGGILVVADWNQRDD----------------R--QQPLNFWERLIMRQLLD--QWAHP----------AFASIEGFAEALAATGLVA-GEV-MTADWTQ--------ET-LPS--WLDSIWQGIVRPEGLIRFGLPGLVKSLREVPTFLLMRI-----------------------------------------------------------------------------------------------------------------------AFGMGL---------------------------CRFGMFRAVRAEIPAVSLEPAPQVNC----------------------------------------------------------------   [328]
'gi|1001725|dbj|BAA10562.1| delta(24)-sterol C-methyltransferase [Synechocystis sp. PCC 6803] >gi|16331764|ref|NP 442492.1| delt'     ------------------------------------------------------------------------------------M------------------------------------------------------------------------------------------------------------------------------------------VYHVRPKHALFLAFYCYFSLLTMASATIAS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADLYEKIKNF------YDDS------SGL-WEDVW-----GE-----------------HMHHGY------------------------YG-P------HGT-----YR--ID--RRQAQIDLIKELLAWAV-PQ--------------NSAKPRK-----------ILDLGCGIGGSSLYLAQQH-QAE--VMGASL-SPVQVERAGERARAL--G-------------------------LG-ST----------------CQFQVANA-LDLP--FA--SDSFDWVWSLESGEHMPNKAQFLQEAWRVLKPGGRLILATWCHRPI----------------DPGNGPLTADERRHLQAIYD--VYCLP----------YVVSLPDYEAIARECGF---GEI-KTADWSV--------AV-APF--WDRVIESAF--DPRVLWALGQAGPKIINAALCLRLMKW-----------------------------------------------------------------------------------------------------------------------GYERGL---------------------------VRFGLLTGIKPLV-----------------------------------------------------------------------------   [317]
'gi|27753584|dbj|BAC55218.1| methyltransferase [Streptomyces sp. TP-A0274]'                                    ------------------------------------------------------------------------------------MTDSTQT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPVPEAVGEL------YDRL----TLSAM-NDGSF-----NP-----------------NVHIGY------------------------W--D------TPGSEAT---------IEEAMDRLTDVFIERLN-AY-----------------ATSH-----------VLDLGCGVGGPGLRVVART-GAR--VTGISI-SEEQIRTANRLAAEA--G-------------------------VA-DR----------------AVFQHGDA-MKLP--FA--DASFDAVMALESICHMPDRQQVFTEVSRVLRPGGRIVLTDIFERHP----------------------RKAVRHPGIDKFC---RDLMS----------TTADIDDYVALLHRSGL---RLR-EIVDVTE--------QTTLR---LADEIGRLA----------------------------------------------------------------------------------------------------------------------------------------------------AVEERP-VAMDEGNFDFGDDSFKPSDLAGVDD-FGCLLVTAERP-------------------------------------------------------------------------------   [280]
'gi|78713480|gb|ABB50657.1| SAM (and some other nucleotide) binding motif precursor [Prochlorococcus marinus str. MIT 9312] >gi|'     ------------------------------------------------------------------------------------M---------------------------------------------------------------------------------------VELFLPFFLLVLFLLALFFV-------------------------------------------------------------------------------------------------WRINPRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSGTVASA------YDAW----TQDKL-LERLW-----GE-----------------HIHLGF------------------------Y--P------SDG-----KN--ID--FRKAKVQFVHELVKWSG-LD--------------KLPKGSR-----------ILDVGCGIGGSSRILAKYY-GFN--VTGITI-SPAQVKRAKELTPLG-------------------------------LN----------------CNFQVMDA-LNLK--FK--DGSFDAVWSVEAGAHMNDKTKFADEMLRTLRPGGYLALADWNSRDL----------------R--SYPPSFFEKLVLKQLLD--QWVHP----------DFISINEFANILSTNKNSA-GRV-VSENWNF--------YT-NPS--WYDSIIEGIRRPSAILTLGPLAIVKSIREIPTILLMNW-----------------------------------------------------------------------------------------------------------------------AFRKGL---------------------------MEFGVYKCRG--------------------------------------------------------------------------------   [311]
'gi|4731341|gb|AAD28458.1| MitN [Streptomyces lavendulae]'                                    ------------------------------------------------------------------------------------MTET------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASASDRMVEL------YNRV----T--DL-MVHAE-----GG-----------------YMHGGY------------------------WA--------GPDVPTT---------VEEAGDRLTDYVSERLR-LA-----------------PGER-----------VLDVGSGNGKATLRIAARH-GVR--ATGVSI-NPYQVGLSRQLAEKE--G--------------------------D-EA----------------TEFRIGDM-LALP--FP--DGSFDACYAIESICHALERADVFTEIARVLRPGGRVTVTDFVLRRP----------------------LSDASRTIVDTAND--NFQQG----------PVLTREAYEDCMRSVGL---EVV-EFLDIGD--------EV-RPS--YEAVAAKMR----------------------------------------------------------------------------------------------------------------------------------------------------AARDELGSHMDD--EAFHRMVDGIDRMGSVEE-VGYSVVTARKPA------------------------------------------------------------------------------   [275]
'gi|78169886|gb|ABB26983.1| probable sterol-C-methyltransferase [Synechococcus sp. CC9902] >gi|78185592|ref|YP 378026.1| probabl'     ------------------------------------------------------------------------------------M-----LASL------------------------------------------------------------------------------------LLLTGATAALSCWL-------------------------------------------------------------------------------------------------WLKRDRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQSSESVAAA------YDAW----TDDRL-LERLW-----GD-----------------HVHLGH------------------------Y--G------DPP-----RR--QD--FREAKAAFVHELVRWSG-LD--------------QLPAGSK-----------VLDVGCGIGGSARILARDY-NLE--VVGISI-SPAQIARATELTPQG-------------------------------LP----------------CRFEVMDA-LDLQ--LA--DHSFDAVWSVEAGPHMPDKQQYADELLRVLKLGGLLAVADWNRRDP----------------S--DGAMTKTERKVMRQLLN--QWAHP----------EFASIAGFQQNLETSRYGQ-GGI-STGDWSQ--------AT-LPS--WIDSIVEGLRRPKAVLGLGPKAVIQGLRETPTLLLMHW-----------------------------------------------------------------------------------------------------------------------AFATGL---------------------------MQFGVFKLKRH-------------------------------------------------------------------------------   [310]
'gi|75701026|gb|ABA20702.1| Cyclopropane-fatty-acyl-phospholipid synthase [Anabaena variabilis ATCC 29413] >gi|75907301|ref|YP 3'     ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNWLFSTLVFFLTLLAAGIAL-------------------------------------------------------------------------------------------------YLITARR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQSSNSVANS------YDQW----TEDGI-LEFYW-----GE-----------------HIHLGH------------------------Y--G------SPP-----QR--KD--FLAAKSDFVHEMVRWGG-LD--------------KLPPGTT-----------LLDVGCGIGGSSRILARDY-GFA--VTGITI-SPQQVQRAQELTPQE-------------------------------LN----------------AQFLVDDA-MALS--SP--DGSFDVVWSIEAGPHMPDKAIFAKELMRVLKPGGIMVLADWNQRDD----------------R--QKPLNIWEKPVMQQLLD--QWSHP----------AFSSIEGFSELLAATGLVE-GEV-ITADWTK--------QT-LPS--WLDSIWQGIVRPEGLVRFGLSGFIKSLREVPTLLLMRL-----------------------------------------------------------------------------------------------------------------------AFGMGL---------------------------CRFGMFRALRANTVTPPAEQTTGIKVAQR-------------------------------------------------------------   [330]
lcl|Smo_SMT1_4_1_unnamed_protein_product                                    -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?IFLNSITMAVETQELEVF------YDEG------CVV-YEAVW-----GE-----------------HMHSGY------------------------FD-A------DNT---------RD--FRVAQIRMLEELLAWAG-VP------------GDDQSRPRN-----------ILDVGCGFGGTSRYLSNKY-SAN--VTGIAL-SEYEIARARAITKAE--G-------------------------VC-DK----------------VAFQVADA-LSLP--FE--DNQYDLVWCMECADHIADKLKLMQEMTRVAKPGGWVVLTGWCHREF----------------THGETSLKKHELKILDKIRA--AYLLP----------PWCPTSEYKIIAIDSGL---QEV-NVEDWTR--------HM-LPF--WGLLTAEIF--TLRGAFKILTS?-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [261]
'gi|67921787|ref|ZP 00515304.1| probable delta(24)-sterol C-methyltransferase [Crocosphaera watsonii WH 8501] >gi|67856379|gb|EA'     ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYLYYTLGFIAVVLVIGVVV-------------------------------------------------------------------------------------------------YLVTPRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YESSDTVATS------YDEW----TQDGI-LEFYW-----GE-----------------HIHLGH------------------------Y--G------SPP-----RS--KD--FLEAKADFVHEMVKWGG-LD--------------KLPRGTT-----------VLDVGCGIGGSSRILAKAY-GFE--TTGVTI-SPKQVQRATELTPED-------------------------------VT----------------AKFQVDDA-LNLS--FP--DNSFDVVWSIEAGPHMPDKAKYAQEMVRVLKPGGLLVVADWNQRDD----------------R--QKPLNFWEKPVMRQLLD--QWSHP----------SFSSIEGFSEQIAATGLIE-GEV-ITADWTK--------ET-LPS--WLESIWQGIVRPQGLIKFGFSGFIKSLREVPTMLLMRL-----------------------------------------------------------------------------------------------------------------------GFGAGL---------------------------CRFGMFRAIKSPSVSQSTQTAKGETVNV--------------------------------------------------------------   [328]
'gi|46138453|ref|XP 390917.1| hypothetical protein FG10741.1 [Gibberella zeae PH-1] >gi|42552155|gb|EAA74998.1| hypothetical pro'     ------------------------------------------------------------------------------------MAVAI------SEEQATDLSKQYDTPLGLAHSTM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVLKDRIKLH------YDLA------SDY-YLSLW-----GE-----------------HIHHGY------------------------WP-T--------------EESEATQTKEEAQANLIQLLLDISK-IP-----------------SKSS-----------VLDVGCGIGGTSRYLASKH-GSS--VTGITI-STKQVEIADRLTKAAVEDGASL----------PDVSDAHGFIKLGGGK----------------VKFLELDA-EKMGDSFSGQQGSFDAVWISEALSHFPNKALFFENVMKVLKPGGKLVLADWFKAED---------------------LDDTTFINDIKPIED--GMLLP----------PLCTQQGYLDLAKQAGL---QVFAEPKDISQ--------QV-RKT--WDITWSLVQ--NPSLWAFAFTQGRDGIAFLQSFRAMRR-----------------------------------------------------------------------------------------------------------------------GYANGS---------------------------FRYSVMAFQKEMA-----------------------------------------------------------------------------   [330]
'gi|81299407|ref|YP 399615.1| delta(24)-sterol C-methyltransferase [Synechococcus elongatus PCC 7942] >gi|56685895|dbj|BAD79117.'     -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPMSPLWLLLVLPVSLLAI-------------------------------------------------------------------------------------------------YLLTPRR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQSSDSVAQA------YDSW----TQDGI-LEFYW-----GE-----------------HIHLGH------------------------Y--G------NPL-----RR--KD--FRAAKADFVHEMVRWGN-LD--------------RLPAGTT-----------VLDVGCGIGGSSRILARDY-HFD--VTGITI-SPGQVQRARSLTPDG-------------------------------VT----------------AQFKVDDA-LNLS--FP--DASFDVVWCIEAGPHMPDKALFAKELLRVLKPGGTLVVADWNQRDT----------------R--RRSLQGWERWVMRQLLD--QWAHP----------EFASIEGFSELLEATGWVD-GAV-TTADWTR--------ET-LPS--WLDSIWQGILRPAGLVRFGFSGLIKSLREVPTLILMRI-----------------------------------------------------------------------------------------------------------------------AFGQGL---------------------------CRFGMFRATRA-------------------------------------------------------------------------------   [310]
'gi|27753579|dbj|BAC55213.1| methyltransferase [Streptomyces sp. TP-A0274]'                                    ------------------------------------------------------------------------------------MTQQS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTTADSVGEV------YDQF----A--DAGASTAM-----GG-----------------NIHVGY------------------------W--D------DDDPEVP---------IAEATDRLTDLVAERLA-LR-----------------PDRQ-----------LLDVGCGIGVPALRIAGAH-DVR--VTGITV-SQQQVTEAAARAVES--D-------------------------AG-GR----------------VSFRLADA-MDLP--FE--DVSFDGAFAIESLLHLPDQTPALKEIHRVVRPGGRLVIADLCQRQP----------------------FTGADKEVLDGMLL--MYEIA----------GINTPEEHHARLAEAGW---ELL-ELTDIGE--------QV-RAS--YGHAAAAFR----------------------------------------------------------------------------------------------------------------------------------------------------GLAGALDAGAA---QQMNAAADLMEAFGGHPY-AGYVLITAQRS-------------------------------------------------------------------------------   [276]
'gi|29122988|gb|AAO65792.1| monensin 3-O-methyl transferase; MonE [Streptomyces cinnamonensis]'                                    ------------------------------------------------------------------------------------MNKTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APEPSDIGHY------YDHK----VF-DL-MTQLG-----DG-----------------NLHYGY------------------------WF-D------GGEQQAT---------FDEAMVQMTDEMIRRLD-PA-----------------PGDR-----------VLDIGCGNGTPAMQLARAR-DVE--VVGISV-SARQVERGNRRAREA--G-------------------------LA-DR----------------VRFEQVDA-MNLP--FD--DGSFDHCWALESMLHMPDKQQVLTEAHRVVKPGARMPIADMVYLNP----------------------DPSRPRTATVSD----TTIYA----------ALTDIGDYPDIFRAAGW---TVL-ELTDITR--------ET-AKT--YDGYVEWIR----------------------------------------------------------------------------------------------------------------------------------------------------AHRDEYVDIIGV--EGYELFLHNQAALGKMPE-LGYIFATAQRP-------------------------------------------------------------------------------   [276]
lcl|Smo_SMT1_19_1_unnamed_protein_product                                    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKGFK-------------------------TGIFKYAVVMGKK------VPVSASVCVLAMASEIEEF------YDEG------CVV-YEAVW-----GE-----------------HMHSGY------------------------FE-A------GKP---------GD--FRVAQVRMIEEVLSWAG-VP------------NDEQSRPRD-----------ILDVGCGFGGTSRYLSKKY-SAN--VKGIAL-SDYEIARAKAIARAE--G-------------------------VS-DK----------------VTFQVANA-LNQP--FE--DGQFDLVWCMECAVHIEDKLKLVQEMARVTKPGGRVVLVSWCHREL----------------KPGETSLKKDEQALLDKICA--AYFFP----------PWCATSEYETLACNAGL---Q------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [245]
'gi|84519189|ref|ZP 01006538.1| ubiE/COQ5 family protein methyltransferase [Prochlorococcus marinus str. MIT 9211] >gi|84513938|'     ------------------------------------------------------------------------------------M-----GTLI------------------------------------------------------------------------------------SLLVGILLILIIWI-------------------------------------------------------------------------------------------------WLKTNRA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YKSKSSVSLA------YDSW----TNDRL-LERLW-----GE-----------------HIHLGY------------------------Y--K------DSS-----VK--TD--FRQAKVDFVHQLVKWSG-MD--------------HLPKGSR-----------ILDIGCGIGGSARILARDY-NFD--VLGITI-SPLQVRRAQELTPED-------------------------------ST----------------CRFEVMDA-LDLQ--LE--NGSFDGVWSVEAGPHIPDKQLYADEMLRVLRPGGVLAVADWNRRDI----------------Q--KKKYDFLEELVLRQLLN--QWAHP----------EFSTINAFQKNLSNSAYSA-GTA-DTDDWTR--------FT-IPS--WNDSIIEGIKRPKVFFDLGPKSFYKGFREIPTILLMRW-----------------------------------------------------------------------------------------------------------------------AFSVGL---------------------------MEFGVFRTRG--------------------------------------------------------------------------------   [309]
'gi|13162639|gb|AAG23267.1| methyltransferase-like protein [Saccharopolyspora spinosa]'                                    ------------------------------------------------------------------------------------MLPGG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APTSQQVGQM------YDLV----T--PL-LNSVA-----GG---------------PCAIHHGY------------------------WE-N--------DGRAS---------WQQAADRLTDLVAERTV-LD-----------------GGVR-----------LLDVGCGTGQPALRVARDN-AIQ--ITGITV-SQVQVAIAADCARER--G-------------------------LS-HR----------------VDFSCVDA-MSLP--YP--DNAFDAAWAMQSLLEMSEPDRAIREILRVLKPGGILGVTEVVKREA--------------------------------------GGGMPVSGDRWPTGLRICLAEQLLESLRAAGF---EIL-DWEDVSS--------RT-RYF--MPQFAEELA----------------------------------------------------------------------------------------------------------------------------------------------------AHQHGIADRYGP--AVAGWAAAVCDYEKYAHD-MGYAILTARKPVG-----------------------------------------------------------------------------   [275]
lcl|3820_Cre_unnamed_protein_product                                    ------------------------------------------------------------------------------------MPSTALQGHTLPSSSACLGRATRHVCRVSTRSRR-----------------------------------------------------------------------------------------------------------------AVTVRAGPLETLVKPLTTLGKV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDLKVGIANF------YDES------SEL-WENMW-----GE-----------------HMHHGY------------------------YP-K------GAP--------VKS--NQQAQIDMIEETLKVAG-VT-----------------QAKK-----------MVDVGCGIGGSSRYISRKF-GCT--SNGITL-SPKQAARANALSKEQ--G-------------------------FG-DK----------------LQFQVGDA-LAQP--FE--AGAFDLVWSMESGEHMPDKKKFVSELARVCAPGGTVIVVTWCHRVL----------------GPGEAGLREDEKALLDRINE--AYYLP----------DWCSVADYQKLFEAQGL---TDI-QTRDWSQ--------EV-SPF--WGAVIATAL--TSEGLAGLAKAGWTTIKGALVMPLMAE-----------------------------------------------------------------------------------------------------------------------GFRRGL---------------------------IKFNLISGRKLQQ-----------------------------------------------------------------------------   [338]
'gi|71674252|ref|ZP 00671999.1| similar to Methylase involved in ubiquinone/menaquinone biosynthesis [Trichodesmium erythraeum I'     ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYLYYALGFILLLVALGIVI-------------------------------------------------------------------------------------------------YLITPRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YESSNTVANS------YDDW----TQDGI-LEFYW-----GE-----------------HIHLGH------------------------Y--G------SPP-----RR--KD--FLQAKADFVHEMVKWGG-LD--------------KLPRGTT-----------VLDVGCGIGGSSRILAKEY-EFE--VTGVTI-SPKQVQRATELTPQG-------------------------------VT----------------AKFQVDDA-LALS--FP--DNSFDVVWSIEAGPHMPDKVKYGSEMMRVLKPGGILVVADWNQRDD----------------R--QKPLNYWEKPVMRQLLD--QWSHP----------AFSSIEGFSEQIAETGLVE-GEV-ATADWTQ--------ET-LPS--WFESIWQGIVRPKGLIKFGFSGFIKSLREVPTMLLMRL-----------------------------------------------------------------------------------------------------------------------GFGAGL---------------------------CRFGMFRAVKSNSVPVSTETATTEVANA--------------------------------------------------------------   [328]
'gi|61657538|emb|CAI59122.1| gamma-tocopherol methyltransferase [Chlamydomonas reinhardtii]'                                    ------------------------------------------------------------------------------------MPSTALQGHTLPSSSACLGRATRHVCRVSTRSRR-----------------------------------------------------------------------------------------------------------------AVTVRAGPLETLVKPLTTLGKV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDLKVGIANF------YDES------SEL-WENMW-----GE-----------------HMHHGY------------------------YP-K------GAP--------VKS--NQQAQIDMIEETLKVAG-VT-----------------QAKK-----------MVDVGCGIGGSSRYISRKF-GCT--SNGITL-SPKQAARANALSKEQ--G-------------------------FG-DK----------------LQFQVGDA-LAQP--FE--AGAFDLVWSMESGEHMPDKKKFVSELARVCAPGGTVIVVTWCHRVL----------------GPGEAGLREDEKALLDRINE--AYYLP----------DWCSVADYQKLFEAQGL---TDI-QTRDWSQ--------EV-SPF--WGAVIATAL--TSEGLAGLAKAGWTTIKGALVMPLMAE-----------------------------------------------------------------------------------------------------------------------GFRRGL---------------------------IKFNLISGRKLQQ-----------------------------------------------------------------------------   [338]
'gi|29827478|ref|NP 822112.1| C5-O-methyltransferase [Streptomyces avermitilis MA-4680] >gi|29604577|dbj|BAC68647.1| C5-O-methyl'     ------------------------------------------------------------------------------------MMAVPEQT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPSSLEVGDY------YDRL----T--DL-MNRAL-----GG-----------------NTHLGY------------------------W--P------QPGDGSS---------PGKAADRLTDLLIGKLR-GI-----------------TGRR-----------VLDVGCGSGKPAVRLALSA-PVD--VVGVTV-SEVQVGLATALAKQS--H-------------------------VA-DR----------------VVFTRADA-MELP--FP--DGSFDAAWALECLLHMPSPAQVIREIARVLRPGGRLAVTDVALRAF---------------------GRTGMKRGECTSQ----LLAVP----------ALVHIDEYAGMIADAGL---ELH-ELTDIGD--------QVVGPS--FAALRDHVN----------------------------------------------------------------------------------------------------------------------------------------------------EHLDEYAAAFGIGVAEMRKVVAQCTTLPWTPD-IGYVVLTARRPGE-----------------------------------------------------------------------------   [283]
lcl|Smo_SMT1_5_1_unnamed_protein_product                                    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGEIEEF------YDEG------CVV-YEALW-----GE-----------------HMHSGY------------------------FE-A------GKP---------GD--FRVAQVRMIEEVLSWAG-VP------------NDEQSRPRD-----------ILDVGCGFGGTSRYLFKKY-SAN--VKGIAL-SDYEIARAKAIARAE--G-------------------------VS-DK----------------VTFQVANA-LNQP--FE--DGQFDLVWCMECAVHIEDKLKLMQEMARVTKPGGRVVLVSWCHREL----------------KPGETSLKKHEQALLDKICA--AYFFP----------PWCATSEYETLARNAGL---Q------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [215]
'gi|80971653|gb|ABB52799.1| gamma-tocopherol methyltransferase [Helianthus annuus]'                                    ------------------------------------------------------------------------------------M---------------------------------------------------------------------ATTAVGVSATPMTEK--------------------------------------------------------------------------LTAADDDQQQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKLKKGIAEF------YDES------SGM-WENIW-----GE-----------------HMHHGY------------------------YN-S------DDV-----VEL-SD--HRSAQIRMIEQALTFAY-VS------------DDPEKKPKT-----------IVDVGCGIGGSSRYLARKY-GAE--CHGITL-SPVQAERANALAAAQ--G-------------------------LA-DK----------------VSFQVADA-LNQP--FP--DGKFDLVWSMESGEHMPDKLKFVSELTRVAAPGATIIIVTWCHRDL----------------NPGEKSLRPEEEKILNKICS--SFYLP----------AWCSTADYVKLLESLSL---QDI-KSADWSG--------NV-APF--WPAVIKTAL--SWKGITSLLRSGWKSIRGAMVMPLMIE-----------------------------------------------------------------------------------------------------------------------GFKKDV---------------------------IKFSIITCKKPE------------------------------------------------------------------------------   [314]
'gi|80971662|gb|ABB52803.1| gamma-tocopherol methyltransferase [Helianthus annuus] >gi|80971655|gb|ABB52800.1| gamma-tocopherol'      ------------------------------------------------------------------------------------M---------------------------------------------------------------------ATTAVGVSATPMTEK--------------------------------------------------------------------------LTAADDDQQQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKLKKGIAEF------YDES------SGM-WENIW-----GE-----------------HMHHGY------------------------YN-S------DDV-----VEL-SD--HRSAQIRMIEQALTFAS-VS------------DDPEKKPKT-----------IVDVGCGIGGSSRYLARKY-GAE--CHGITL-SPVQAERANALAAAQ--G-------------------------LA-DK----------------VSFQVADA-LNQP--FP--DGKFDLVWSMESGEHMPDKLKFVSELTRVAAPGATIIIVTWCHRDL----------------NPGEKSLRPEEEKILNKICS--SFYLP----------AWCSTADYVKLLESLSL---QDI-KSADWSG--------NV-APF--WPAVIKTAL--SWKGITSLLRSGWKSIRGAMVMPLMIE-----------------------------------------------------------------------------------------------------------------------GFKKDV---------------------------IKFSIITCKKPE------------------------------------------------------------------------------   [314]
'gi|80971659|gb|ABB52802.1| gamma-tocopherol methyltransferase [Helianthus annuus] >gi|80971657|gb|ABB52801.1| gamma-tocopherol'      ------------------------------------------------------------------------------------M---------------------------------------------------------------------ATTAVGVSATPMTEK--------------------------------------------------------------------------LTAADDDQQQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKLKKGIAEF------YDES------SGM-WENIW-----GE-----------------HMHHGY------------------------YN-S------DDV-----VEL-SD--HRSAQIRMIEQALTFAS-VS------------DDLEKKPKT-----------IVDVGCGIGGSSRYLARKY-GAE--CHGITL-SPVQAERANALAAAQ--G-------------------------LA-DK----------------VSFQVADA-LNQP--FP--DGKFDLVWSMESGEHMPDKLKFVSELTRVAAPGATIIIVTWCHRDL----------------NPGEKSLRPEEEKILNKICS--SFYLP----------AWCSTADYVKLLESLSL---QDI-KSADWSG--------NV-APF--WPAVIKTAL--SWKGITSLLRSGWKSIRGAMVMPLMIE-----------------------------------------------------------------------------------------------------------------------GFKKDV---------------------------IKFSIITCKKPE------------------------------------------------------------------------------   [314]
'gi|88807947|ref|ZP 01123458.1| probable sterol-C-methyltransferase [Synechococcus sp. WH 7805] >gi|88787986|gb|EAR19142.1| prob'     ------------------------------------------------------------------------------------MPLPAFLGP-------------------------------------------------------------------------------------AAIGVAAAAGAYVL-------------------------------------------------------------------------------------------------WSRRNRA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YLSSESVASA------YDAW----TEDRL-LETLW-----GD-----------------HVHLGH------------------------Y--G------APP-----RN--KD--FRRAKADFVHELVRWSG-LD--------------QLPPGAK-----------VLDVGCGIGGSARILARDY-GFD--VLGVSI-SPAQIRRATELTPEG-------------------------------MT----------------CRFAVMDA-LDLE--LN--DGEFDAVWSVEAGPHMPDKQRYADELLRMIRPGGMLAIADWNRRDP----------------L--DGPLNRQERWVMHQLLT--QWAHP----------EFASIRGLQHNLETSVYSK-GPI-AVANWNQ--------QT-LPS--WNDSILEGLRRPSAVLRLGPSAIVQGLRETPTLLLMRW-----------------------------------------------------------------------------------------------------------------------AFARGM---------------------------MQFGVFRLNGDQERSELG------------------------------------------------------------------------   [321]
'gi|68270865|gb|AAY88923.1| BusF [Saccharopolyspora pogona]'                                    ------------------------------------------------------------------------------------MLPGG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPTSQQVGQM------YDLV----T--PL-LNSVA-----GG---------------PCAIHHGY------------------------WE-N--------DGRTS---------WQQAADRLTDLVAERTA-LD-----------------GGNR-----------LLDVGCGTGQPALRVARDN-AIR--ITGITV-SQVQAAIAVDCARER--G-------------------------LS-HQ----------------VDFSCVDA-MSLP--YP--DNAFDAAWAIQSLLEMSEPDRAIREIVRVLKPGGILGVTEVVKREI--------------------------------------GSGIPVSWDMWPTGLRICLAEQLLESLCAAGF---EIL-ACDDVSS--------RT-RYF--MPQFAEALA----------------------------------------------------------------------------------------------------------------------------------------------------AHQHGIAERYGP--AVADWAAAVCDYEKYADD-MGYAILTARKPVG-----------------------------------------------------------------------------   [275]
'gi|39940678|ref|XP 359876.1| hypothetical protein MG04901.4 [Magnaporthe grisea 70-15]'                                    ------------------------------------------------------------------------------------MSAATKQ--DTKQDDATDLSREYDTPLGLAHTTM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALKDRIKLH------YDLA------SDY-YLSLW-----GQ-----------------HVHHGY------------------------WP-T--------------DESKAKDTKEVAQTNLIDLLLEISK-IP-----------------EGGS-----------VLDVGCGLGGTTRHLASKL-GCS--VTGITI-SGKQVEIAKRLTKTEAEAEATKLGKDVAAAKAEVEEDADGFMKVGKGK----------------VRFIELDA-ETMGEYFSG-KDAFDAVWICEALSHFPNKELFFQNVHAVLKPGGCLTLADWFKAEG---------------------LTQKQFDDDIKPIED--GMLTP----------PLNTQAGYVDKAKAAGL---KVLTEPKDISQ--------DV-KQT--WDITWSLIQ--KPSLWAFALSQGRDGIAFLQSFRAMRR-----------------------------------------------------------------------------------------------------------------------GYANNN---------------------------FRYAVMSFEK--------------------------------------------------------------------------------   [340]
'gi|33635636|emb|CAE21960.1| SAM (and some other nucleotide) binding motif [Prochlorococcus marinus str. MIT 9313] >gi|33864052|'     ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MILAGTTLTSAVVI-------------------------------------------------------------------------------------------------WTQRDRR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YKSSASVASA------YDAW----TNDQL-LERLW-----GE-----------------HVHLGY------------------------Y--G------KPP-----ST--RD--FRAAKQDFVHELVQWSG-LA--------------QLPRGSR-----------VLDVGCGIGGSARILARDY-NFD--VLGITI-SPAQVKRASQLTPEG-------------------------------MT----------------CQFQVMDA-LDLK--LA--NGSFDAVWSVEAGPHMPDKQRYADELLRVLRPKGVLAVADWNRRDY----------------E--DGEMTSLERWVMRQLLD--QWAHP----------EFASIKGFRRNLLHSPFAC-GTV-ESDDWTR--------SI-LPS--WNDSILEGFRRPGAVLGLGPAALVKGFREIPTILLMRW-----------------------------------------------------------------------------------------------------------------------AFAHGL---------------------------MQFGVFRSRD--------------------------------------------------------------------------------   [304]
lcl|Smo_SMT1_3_1_unnamed_protein_product                                    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?HIARFHERFDDIDGSTNQQECHRRTLDLEVQMRGLNHSSILAAHSSTILVRVAMAVDNQELEVFYDEGCVVYEAVWGEHMHSGYFDAGNTRDFRAAQIRMLEELLAWAGVPDDEQSRPRNILDVGCGFGGTSRYLSNKYSANVTGIALSKYEIGRARAIAKAEGVCDKVAFQVADALSLPFEDNQYDLVWCMECADHIADKLKLMQEMTRVAKPGGWVVLTGWCHREFTHGETSLKKHELVIDLIKTENKILDKVRAAYLLPPWCQTSDYKVIAIDAGLQGVKVEDWTRHMLPFWGLLTAEIFTLRGAFKILTSEGGKDLAAAAVPVSASVFVFAMAGEIEEF------YDEG------CVV-YEAVW-----GE-----------------HMHSGY------------------------FE-A------GKP---------GD--FRVAQVRMIEEVLSWAG-VP------------NDEQSRPRD-----------ILDVGCGFGGTSRYLSKKY-SAN--VKGIAL-SDYEIARAKAIARAE--G-------------------------VS-DKVDSTPLFGAVSNTYEQVTFQVANA-LNQP--FE--DGQFDLVWCMECAVHIEDKLKLVQEMARVTKPGGRVVLVSWCHREL----------------KPGETSLKKHEQALLDKICA--AYFFP----------PWCATSEYETLARNAGL---Q------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [567]
'gi|78196328|gb|ABB34093.1| probable sterol-C-methyltransferase [Synechococcus sp. CC9605] >gi|78211869|ref|YP 380648.1| probabl'     -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVAGAVGTTGVAL-------------------------------------------------------------------------------------------------WLRRDRR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YESSESVASA------YDAW----TEDRL-LEQLW-----GE-----------------HVHLGH------------------------Y--G------TPP-----GS--FD--FREAKEAFVHELVRWSG-LD--------------QLPAGSR-----------VLDVGCGIGGSARILARDY-GLD--VLGISI-SPAQVERATQLTPSG-------------------------------LS----------------CRFQVMDA-LDLQ--LP--DQSFDAVWSVEAGPHMPNKQRYADELLRAMRPGGLLAVADWNRRDP----------------S--DGGMTRTERWVMRQLLN--QWAHP----------EFASIKGFRQNLDNSVHHR-GEI-VTGDWTQ--------AT-LPS--WIDSIIEGIRRPWAVVSLGPKAVLQGLRETPTLLLMHW-----------------------------------------------------------------------------------------------------------------------AFATGL---------------------------MQFGVFRISKD-------------------------------------------------------------------------------   [304]
'gi|83646388|ref|YP 434823.1| SAM-dependent methyltransferase [Hahella chejuensis KCTC 2396] >gi|83634431|gb|ABC30398.1| SAM-dep'     ------------------------------------------------------------------------------------MP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NQVNEAIENH------YARQ----DVESL-ILAAL-----EGAGKDLHRLTLEDLAPMDAFHLRG-------------------------------------------------------RAATRELAEIVG-LD-----------------ADKR-----------VLDVGCGIGGTSRYLAREY-GCR--VTGIDL-TEEYCRAAAMLSARV--G-------------------------LE-AL----------------TEFRQGDA-VNLP--FE--GESFDTVWTEHAAMNIPDKSRLYHEMYRVLKPGGSLAIHDVLAGPS----------------G---------PVLYPAPWAR--TSDAS----------FLVAPDALRNLLESAGF---TVS-VWVDVTE--------AA-RSW--FAAQLEKTRR---------------------------------------------------------------------RGFPQLGVHVLMGE----------------EFQA-----------------------------MAENQGRN--------LQEGR---------------------------IALAQVVAKK--------------------------------------------------------------------------------   [276]
'gi|71145430|gb|AAZ25903.1| methyltransferase, UbiE/COQ5 family [Colwellia psychrerythraea 34H] >gi|71279690|ref|YP 269982.1| me'     ------------------------------------------------------------------------------------M-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHIHSY------YSPN----NLYNK-IIEGL-----NNLGKDLSSVTPDDLQPVDEFHIRG-------------------------------------------------------DIATKELIELGN-FT-----------------PDMH-----------ILDVGCGVGGSTRRLSHET-GCH--VTGIDL-SDEYIDAAERLTQLL--N-------------------------MQ-AR----------------VKFNVGSA-LELP--YA--DNTFDGAWSIQMNMNVEDKLGWLKEMYRVLKPGARAVLYEVCGHEE-------------------------KTIYFPVPWAQ--DSSMS----------FLIPKEAFRDLIASTGF---KIE-VWNDKSD--------LA-QKA--FARMREPTGE---------------------------------------------------------------------STLPELGLHMLIGN----------------DIKT-----------------------------KAYNMRRN--------LDDER---------------------------ISLIEILAIKPS------------------------------------------------------------------------------   [273]
'gi|14022360|dbj|BAB48970.1| probable sterol methyltransferase [Mesorhizobium loti MAFF303099] >gi|13471618|ref|NP 103184.1| pro'     ------------------------------------------------------------------------------------M---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATVEPGIARH------YDIA----GLEQR-ILAAL-----ADTGVDVAHLRADDLEAVDEFHIGG-------------------------------------------------------VAATRELIGQMG-LK-----------------PGAM-----------LLDIGSGVGGPARFAANEA-GAD--VTGIDL-TQSYVDIATSLSKRA--G-------------------------MA-DR----------------THFVQGSA-LDMP--FA--DAGFDAAMILHVGMNLPDKKKLMGEAARVLKPGGVFAVYDVMRLKD----------------G---------ALTYPLPWAS--DESMS----------FVATPDDYRSAATASGF---SVV-AERRRGA--------FA-IEF--FAAMRARMA-----------------------------------------------------------------AAQAEGKKPPPGVGLVMGE----------------DARS-----------------------------KIANITAA--------LEGGI---------------------------LAPVELLLRLG-------------------------------------------------------------------------------   [280]
'gi|50911847|ref|XP 467331.1| putative gamma-tocopherol methyltransferase [Oryza sativa (japonica cultivar-group)] >gi|51964278|'     ------------------------------------------------------------------------------------MAHAAA----------------------ATGALAPLHPLLRCTSRHLCASASPRAGLCLHHHRRRRRSSRRTKLAVRAMAPTL----------------------------------------------------------------------------SSSSTAAAAP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGLKEGIAGL------YDES------SGV-WESIW-----GE-----------------HMHHGF------------------------YD-A------GEA-----ASM-SD--HRRAQIRMIEESLAFAA-VP------------DDAEKKPKS-----------VVDVGCGIGGSSRYLANKY-GAQ--CYGITL-SPVQAERGNALAAEQ--G-------------------------LS-DK----------------VSFQVGDA-LEQP--FP--DGQFDLVWSMESGEHMPDKRQFVSELARVAAPGARIIIVTWCHRNL----------------EPSEESLKPDELNLLKRICD--AYYLP----------DWCSPSDYVKIAESLSL---EDI-RTADWSE--------NV-APF--WPAVIKSAL--TWKGLTSLLRSGWKTIRGAMVMPLMIE-----------------------------------------------------------------------------------------------------------------------GYKKGL---------------------------IKFTIITCRKPETTQ---------------------------------------------------------------------------   [362]
'gi|87125025|ref|ZP 01080872.1| probable sterol-C-methyltransferase [Synechococcus sp. RS9917] >gi|86167345|gb|EAQ68605.1| proba'     ------------------------------------------------------------------------------------MLNATGFALA------------------------------------------------------------------------------------LGIPTAAAAVGLAI-------------------------------------------------------------------------------------------------WSRRNRA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHSSASVAAA------YDAW----TDDRL-LEQLW-----GE-----------------HVHLGH------------------------Y--G------EPP-----RR--RD--FRAAKADFVHALVHWSG-LD--------------QLPPGSR-----------LLDVGCGIGGSARILAREY-GFD--VLGISI-SPAQVARATSLTPTG-------------------------------LS----------------CRFAVMDA-LDLK--LA--DGQFDAVWSVEAGPHMPDKQRYADELLRVLRPGGVLAVADWNRRDV----------------S--DGAMSGLERQVMHQLLT--QWAHP----------EFASIKGFGANLNASPYNHGGTI-VSADWTA--------AT-LPS--WIDSIMEGVRRPGAVLSLGPKAVLQGLRETPTLLLMHW-----------------------------------------------------------------------------------------------------------------------AFATGL---------------------------MQFGVFRRD---------------------------------------------------------------------------------   [314]
'gi|80971651|gb|ABB52798.1| gamma-tocopherol methyltransferase [Helianthus annuus]'                                    ------------------------------------------------------------------------------------M---------------------------------------------------------------------ATTAVGVSATPMTEK--------------------------------------------------------------------------LTAADDDQQQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKLKKGIAEF------YDES------SGM-WENIW-----GE-----------------HMHHGY------------------------YN-S------DDV-----VEL-SD--HRSAQIRMIEQALTFAS-VS------------DDPEKKPKT-----------IVDVGCGIGGSSRYLARKY-GAE--CHGITL-SPVQAERANALAAAQ--G-------------------------LA-DK----------------VSFQVADA-LNQP--FS--DGKFDLVWSMESGEHMPDKLKFVSELTRVAAPGATIIIVTWCHRDL----------------NPGEKSLRPEEEKILNKICS--SFYLP----------AWCSTADYVKLLESLSL---QDI-KSADWSG--------NV-APF--WPAVIKTAL--SWKGITSLLRSGWKSIRGAMVMPLMIE-----------------------------------------------------------------------------------------------------------------------GFKKDV---------------------------IKFSIITCKKPE------------------------------------------------------------------------------   [314]
'gi|33634279|emb|CAE19964.1| SAM (and some other nucleotide) binding motif [Prochlorococcus marinus subsp. pastoris str. CCMP198'     ------------------------------------------------------------------------------------M--------------------------------------------------------------------------------------SIFLISSLVIFLTLLFSSLIL-------------------------------------------------------------------------------------------------WRINTRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YISSRTVATA------YDSW----TQDKL-LERLW-----GE-----------------HIHLGF------------------------Y--P------LN------KN--ID--FREAKVQFVHELVSWSG-LD--------------KLPRGSR-----------ILDVGCGIGGSSRILANYY-GFN--VTGITI-SPAQVKRAKELTPYE-------------------------------CK----------------CNFKVMDA-LDLK--FE--EGIFDGVWSVEAGAHMNNKTKFADQMLRTLRPGGYLALADWNSRDL----------------Q--KQPPSMIEKIILKQLLE--QWVHP----------KFISINEFSSILINNKNSS-GQV-ISSNWNS--------FT-NPS--WFDSIFEGMRRPNSILSLGPGAIIKSIREIPTILLMDW-----------------------------------------------------------------------------------------------------------------------AFKKGL---------------------------MEFGVYKCRG--------------------------------------------------------------------------------   [311]
'gi|66732623|gb|AAY52459.1| gamma-tocopherol methyltransferase [Lotus corniculatus var. japonicus]'                                   ------------------------------------------------------------------------------------MATMMM-----------------SIFPPPPSV-ASLFILSHCTHTIRVQSTTQFTGFSI-----------RTRTRD-CSRILLTE--------------------------------------------------------------------------EREMAVMEEK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLLQTGIAEF------YDES------SGL-WEDMW-----GD-----------------HMHHGF------------------------YE-Q------DVT-----VSV-SD--HRVAQIRMIEESLRFAA-LS------------EDPAKKPES-----------IVDVGCGIGGSSRYLAKKF-QAK--SVGITL-SPVQAQRANALAASQ--G-------------------------LA-DK----------------VSFQVADA-LEQP--FP--DGQFDLVWSMESGEHMPDKPKFVGELARVAAPGGTIIIVTWCHRDL----------------GPAEESLQPWEQNLLKRICD--AFYLP----------AWCSTADYVKLLESHSL---QDI-KSADWSP--------FV-APF--WPAVIRSAF--TWKGLTSLLRSGMKTIKGALAMPLMIE-----------------------------------------------------------------------------------------------------------------------GFKKGV---------------------------IKFAIVTCRKPENVEIE-------------------------------------------------------------------------   [358]
'gi|68234074|ref|ZP 00573171.1| UbiE/COQ5 methyltransferase [Frankia sp. EAN1pec] >gi|68198304|gb|EAN12579.1| UbiE/COQ5 methyltr'     ------------------------------------------------------------------------------------MAHPT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SALAAEVGKF------YDHL----T--TYQTAQDE-----DL-----------------NFHFGY------------------------W--D------VPPDGTPPAPGTDVAELEAAAERLTELMIEKIR-VR-----------------TGDR-----------VLDVGSGSGIPAVRLTRAT-GAS--VVGISI-SREQVRRSTDRARDE--N-------------------------LS-DR----------------LEFEYADA-AELP--FG--PDSFDAAWALESIIHVPDRAQVLREIARVIRPGGRFVATDIFERSP----------------------VPDEKRHAVDSFYS--GLLLG----------PSVRFDDYPALLRGAGL---RPL-ELIDVSD--------QVIARS--FQLLAERIR----------------------------------------------------------------------------------------------------------------------------------------------------RDKENLDDLLGD--ELYQRLAST--GVDGLRE-IGYLVVVAERPTE-----------------------------------------------------------------------------   [287]
'gi|72256521|gb|AAZ67143.1| gamma tocopherol methyltransferase [Triticum aestivum]'                                    ------------------------------------------------------------------------------------MANSAAL----LHSLLSTGWTPRRRLDRASATRLAPSPGLSC----------------------------RSSRPTRSVRPMASS--------------------------------------------------------------------------TTAARADAAP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGLKEGIAGL------YDES------SGL-WESIW-----GE-----------------HMHHGF------------------------YD-S------GEA-----ASM-SD--HRRAQIRMIEEALAFAA-VP------------DDPTNKPKT-----------IVDVGYGIGGSSRYLANKY-GAQ--CSGITL-SPVQAERGNALAAVQ--G-------------------------LS-DK----------------ASFQVADA-LEQP--FP--DGQFDLVWSMESGEHMPNKQKFVSELARVAAPGATIIIVTWCHRNL----------------APSEDSLKPDELNLLKKICD--AYYLP----------DWCSPSDYVKIAESLSL---EDI-KTADWSE--------NV-APF--WPAVIQSAL--TWKGLTSLLRSGWKTIKGALVMPLMIQ-----------------------------------------------------------------------------------------------------------------------GYKKGL---------------------------IKFSIITCHKPQAAIEGEPEAASPRV----------------------------------------------------------------   [365]
'gi|33238640|gb|AAQ00705.1| ubiE/COQ5 family methyltransferase [Prochlorococcus marinus subsp. marinus str. CCMP1375] >gi|332411'     ------------------------------------------------------------------------------------M-----IAFL------------------------------------------------------------------------------------LPIVSLLVLSLIFL-------------------------------------------------------------------------------------------------WLFNDRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YKSSESVSSA------YDSW----TNDRL-LEKLW-----GE-----------------HIHLGY------------------------Y--E------NSY-----KT--KD--FRQAKIDFVHKLAHWSG-LS--------------TLPKGSR-----------IIDIGCGIGGSSRILAKDY-GFD--VVGITI-SSEQVKRANQLTPKE-------------------------------LK----------------CHFEIMNA-LNLK--FE--DGSFDGVWSVEAGPHILNKQLFADEMLRVLRPGGVLAVADWNRRDY----------------A--KKEIGFLNSLVLKQLLN--QWSHP----------DFATIYGFRNNLSDSIYSA-GRV-ETDDWTK--------YT-IPS--WNDSIIEGIRRPNVFFDLGLGSFFKAIREVPTIVLMRW-----------------------------------------------------------------------------------------------------------------------AFHTGL---------------------------MQFGVFRSRG--------------------------------------------------------------------------------   [309]
'gi|78195408|gb|ABB33175.1| conserved hypothetical protein [Geobacter metallireducens GS-15] >gi|78224153|ref|YP 385900.1| hypot'     ------------------------------------------------------------------------------------MSD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTDAQAIADH------WGRG----DVFGL-IVAAL-----NQMAKPLDGLTVEELAPVDHFHSRG-------------------------------------------------------FPATVEFADRLP-IN-----------------AGEQ-----------ILDIGCGLGGPARYMAKRF-QCR--VSGIDI-TGPFVEAANRLTALL--H-------------------------ME-QQ----------------VEIAQGNG-QRLP--YP--DSCFDGAYTQDVTMNVAERAGFFAEAYRVLKPGAFFALSEHGLGPQ----------------G---------KPHYPVPWSD--DGTGA----------YLTAPAETRAILERTGF---EAI-TVEDTGA--------KC-VAG--YGKVIERAEK---------------------------------------------------------------------GALPPLGLHLFMGE----------------SMVE-----------------------------KMRNAARN--------IEEGR---------------------------THPIQLICRKP-------------------------------------------------------------------------------   [278]
lcl|Ppa_SMT1_15_1_unnamed_protein_product                                    ------------------------------------------------------------------------------------?SSISSCNEIRTRSTSVTSAQVCGLIRPDDEVGRRGVKTRSLRSGG-----------------------------------------------------------------------------------------------------------------VVRRAVQRTE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PELYDGIAHF------YDES------SGV-WEGIW-----GE-----------------HMHHGY------------------------Y---------DEEIVEAVVDGDPD--HRRAQIKMIEKSLAYAG-VP------------DSKDLKPKT-----------IVDVGCGIGGSSRYLARKF-QAK--VNAITL-SPVQVQRAVDLTAKQ--G-------------------------LS-DL----------------VNFQVANA-LNQP--FQ--DGSFDLVWSMESGEHMPDKKKFVGELARVAAPGGRIILVTWCHRDL----------------KPGETSLKPDEQDLLDKICD--AFYLP----------AWCSPSDYVSIAKDLGL---Q------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [280]
'gi|9392589|gb|AAF87204.1| glycine-sarcosine-dimethylglycine methyltransferase [Actinopolyspora halophila]'                           ------------------------------------------------------------------------------------MTKSVDDLARGDQAGDEQDPVHREQQTFGDNPLEVRDTDHYMHEYVGGFVDKWDDLIDWKKRYESEGSFFIDQLRARGVETVLDAAAGTGFHSVRLLEEGFETVSADGSPQMLAKAFSNGLAYNGHILRVVNADWRWLNRDVHGEYDAIICLGNSFTHLFSERDRRKTLAEFYAMLKHDGVLIIDQRNYDSILDTGFSSKHTYYYAGEDVSAEPDHIDDGLARFKYTFPDKSEFFLNMYPLRKDYMRRLMREVGFQRIDTYGDFQETYGEDEPDFYIHVAEKSYRTEDEFVDMY----------------------------------------------------------------------------------------------------------------------------------------------------SNAVHTARDY------YNSE----DADNF-YYHVW----GGN-----------------DIHVGL------------------------YQ-T------------------PQEDIATASERTVQRMAGKVD-IS-----------------PETR-----------ILDLGAGYGGAARYLARTY-GCH--VTCLNL-SEVENQRNREITRAE--G-------------------------LE-HL----------------IEVTDGSF-EDLP--YQ--DNAFDVVWSQDSFLHSGDRSRVMEEVTRVLKPKGSVLFTDPMASDS-------------------------AKKNELGPILD--RLHLD----------SLGSPGFYRKELTRLGL---QNI-EFEDLSE--------YL-PVH--YGRVLEVLESRENELAG--------------------------------------------------------------------------------------------FIGE-----------------------------EYRAHMKTGLRNWVQAGNGGS---------------------------LAWGIIHARA--------------------------------------------------------------------------------   [565]
'gi|67929064|ref|ZP 00522248.1| similar to Methylase involved in ubiquinone/menaquinone biosynthesis [Solibacter usitatus Ellin6'     ------------------------------------------------------------------------------------M---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDITTKVREH------YSAT----DLIDR-IKSALAKSVAGRHGASDAAACVAQLAPLDQFHTRG-------------------------------------------------------ILATAELAGAAG-VE-----------------RSTR-----------VLDVGCGIGGPARYLAATF-ECK--VTGLDL-SAGFIDAASYLTARC--G-------------------------LS-DR----------------VTFQVGDG-HHLP--FE--DAGFDAVFLQHVAMNVEDRAGLYAEVRRMLPVGGRFATYDLVLRDG--------------------------DVVYPVPWAR--DASTS----------FLLSEGDTRTALEQAGF---KAV-VWQDDTQ--------TA-LDW--FEAAVGGSR------------------------------------------------------------------------PGGLNLGVVMGP----------------DFPA-----------------------------LTANLARN--------LRENR---------------------------LGVLSAVLTRD-------------------------------------------------------------------------------   [277]
'gi|76882822|gb|ABA57503.1| Methylase involved in ubiquinone/menaquinone biosynthesis-like [Nitrosococcus oceani ATCC 19707] >gi'     ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAKDIHLPY------FDLLLAQLEQENAKLELAF-----GR-----------------HVHWGY------------------------WS-E------------PPQGVVSPKDFAQAAENLSKEIYFAAN-TK-----------------NNQR-----------ILDVGCGFGGTVASLNENFSGME--LIGLNI-DIRQLLRAQEKIKAR----------------------------PG-NV----------------IYFEAADA-CALP--FP--DQSFDVVLAVECIFHFAQRSQFFAEVWRVLKPGGRFAFSDFVSQDF---------------------FSPLMAFSSGWPFSRGFFGHCN----------LQYTLTQYRSLAQAMGF---KER-MEKDITE--------NT-LPT--YAFLRALGKELRIKDPSAKLETWIAEW----------------------------------------------------------------------------------------------------------------------------------ASRLGL---------------------------LRYRVFSFEKLKSG----------------------------------------------------------------------------   [282]
'gi|68560795|ref|ZP 00600104.1| similar to Methylase involved in ubiquinone/menaquinone biosynthesis [Rubrobacter xylanophilus D'     ------------------------------------------------------------------------------------MG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPGERAVGEH------YGRE----GLEER-ISAAL-----RSAGADPLAPSVEELHAVDQLHTRG-------------------------------------------------------VRATLELAELAG-AS-----------------PGER-----------VLDVGGGLGGPARILASRF-GCR--VVVLDV-TEEFCRVGALLTARA--G-------------------------LG-ER----------------VLFRHGSA-LEIP--FP--DASFDLAWTQHSTMNIPDKDRLYREIHRVLKPGGRLAMHEILAGPS------------------------GPPRRFPLPWAA--SPALS----------HLLPPNRMRASLSRAGL---REL-AWSDVTP--------QT-AEW--LKTRSSGRPSGPPPE-------------------------------------------------------------------------------------------------------------------------------AFANLLLS--------IREGR---------------------------ATAVQALLERPEAQLDGNGSR---------------------------------------------------------------------   [275]
'gi|33633223|emb|CAE08428.1| putative sarcosine-dimethylglycine methyltransferase [Synechococcus sp. WH 8102] >gi|33866445|ref|N'     ------------------------------------------------------------------------------------MGTTNG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CAADSVAATY------YDSQ----DADQF-YEQVW----GGE-----------------DIHIGL------------------------YA-T------------------PDEAIATASDRTVHALLDLADPLP-----------------QGGC-----------VVDLGAGYGGASRRLARWS-ERP--VHAINI-SAVENDRHRRLNVDA--G-------------------------LE-QQ----------------ITVHDASF-EQVP--MA--DASADLVWSQDAILHAGDRAKVLAEVSRLLKPGGCFVFTDPMAADG-------------------------VEMGLLQPILD--RIHLP----------DLASPSRYKAWGEAVGL---TME-VWDERTE--------ML-VRH--YDRVRQDTRLRRAELET--------------------------------------------------------------------------------------------SISS-----------------------------GYLDRMDVGLGHWVDGGQQGR---------------------------LSWGLMRLRKPG------------------------------------------------------------------------------   [280]
'gi|89092231|ref|ZP 01165185.1| Methylase involved in ubiquinone/menaquinone biosynthesis-like [Oceanospirillum sp. MED92] >gi|8'     ------------------------------------------------------------------------------------M---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NDHRYPVPSY------FDFL-----IQDF-HEGMG-----NR-----------------MVHLGH------------------------WD-Q-----------PTATQQVNGASFAAAQKALEQELIRMGQ-LE-----------------DGLS-----------VLDVGCGFGSTLQTIDSQFAHMQ--LLGLNI-DPRQIAICEQIKATG--H----------------------------NT----------------LSWQQGDA-CSMP--FP--DQCFDRIFCIEAMFHFPSRQKFFNEVARLLKPNGLLIASDIACTKT-------------------VDHQSIPGFAIEAALFDGYGPWPD----------LWGDEGSHSVMASKSGL---KLE-AFRDVSK--------ET-MPS--HQLTVSSRA----------------------------------------------------------------------------------------------------DGRK-----------------------------DPGSSAQRAAMMLKWLQQQDI---------------------------LQYCYFTLRK--------------------------------------------------------------------------------   [276]
'gi|72002759|gb|AAZ58561.1| UbiE/COQ5 family methyltransferase [Prochlorococcus marinus str. NATL2A] >gi|72382909|ref|YP 292264.'     ------------------------------------------------------------------------------------M----------------------------------------------------------------------------------------QWILILIFSIFCLFTLTNQ-------------------------------------------------------------------------------------------------WVRKSRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YESVNSVASS------YDSW----TNDRL-LENLW-----GE-----------------HIHLGF------------------------Y--E------KPR-----IK--KD--FRKAKVDFVHELVRWSG-LN--------------QLPKGSR-----------VLDVGCGIGGSSRILSDYY-GFD--VIGISI-SQEQVKRARELTANR-------------------------------DF----------------CSFEVMNA-LDLK--FE--KGSFDGVWSVEAGPHILDKQTFADEMLRVLRPGGVLAVADWNQRDS----------------T--KHPLNFFEKLIMNQLLI--QWTHP----------EFSSIEGFKNNLLNSPYCG-SSV-ETSNWTK--------YT-IQS--WNESIYEGFRRPSSILKLGLRSLLKAFKEIPTILMMRW-----------------------------------------------------------------------------------------------------------------------SFSRGL---------------------------MKFGVFKSRG--------------------------------------------------------------------------------   [310]
'gi|62126057|gb|AAX63899.1| gamma-tocopherol methyltransferase [Glycine max]'                                    ------------------------------------------------------------------------------------MATVVR------------------------------IPTISCIHIHTFRSQSPRTFARIRVGPRSWAPIRASAASSERGEIVLEQ-----------------------------------------------------------------------------KPKKDDK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKLQKGIAEF------YDES------SGL-WENIW-----GD-----------------HMHHGF------------------------YD-S------DST-----VSL-SD--HRAAQIRMIQESLRFAS-VS------------EERSKWPKS-----------IVDVGCGIGGSSRYLAKKF-GAT--SVGITL-SPVQAQRANALAAAQ--G-------------------------LA-DK----------------VSFQVADA-LQQP--FS--DGQFDLVWSMESGEHMPDKAKFVGELARVAAPGATIIIVTWCHRDL----------------GPDEQSLHPWEQDLLKKICD--AYYLP----------AWCSTSDYVKLLQSLSL---QDI-KSEDWSR--------FV-APF--WPAVIRSAF--TWKGLTSLLSSGQKTIKGALAMPLMIE-----------------------------------------------------------------------------------------------------------------------GYKKDL---------------------------IKFAIITCRKPE------------------------------------------------------------------------------   [350]
'gi|8778697|gb|AAF79705.1| T1N15.23 [Arabidopsis thaliana] >gi|25405942|pir||F96525 protein T1N15.23 [imported] - Arabidopsis th'     ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYGVNVMQVFQECQTRDASGNSFELSMV---------GCKCIGAYVKNKKNQNQICWIWQKV-S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VENDKDFQRF------LDNVQYKSSGILR-YERVF-----GE----------------GYVSTGG------------------------FG-NSILTLLSSYGHTYLYCLSVIFMFLFSLTETTKEFVAKMD-LK-----------------PGQK-----------VLDVGCGIGGGDFYMAENF-DVH--VVGIDL-SVNMISFALERAI----G-------------------------LK-CS----------------VEFEVADC-TTKT--YP--DNSFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLITDYCRSAE---------------------TPSPEFAEYIKQRGY-----------------DLHDVQAYGQMLKDAGF---DDV-IAEDRTD--------QF-VQV--LRRELEKVEKEKEEFIS--------------------------------------------------------------------------------------------DFSEVKTFLTTNSFEQNTCLLCSHIDHKILLLQEDYNDIVGGWSAKLERTASGE---------------------------QKWGLFIADKK-------------------------------------------------------------------------------   [374]
'gi|16944422|emb|CAC28777.2| conserved hypothetical protein [Neurospora crassa] >gi|85102183|ref|XP 961285.1| hypothetical prote'     ------------------------------------------------------------------------------------MAAVTSQTPQTGQDEVTDLSKQYDTPMGLAHSTM------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QALKDRIKLH------YDLA------SDY-YLNLW-----GE-----------------HIHHGY------------------------WA-T--------------DEAKAKDTKEVAQVNLIRLLLEISK-VS-----------------EGAR-----------VLDTGCGIGGTSRFLASEL-GCT--VTGITI-STKQVEMATRLTKAEAAKQIQG-------DDKTVTPDADGFIALGKGK----------------VRFLELDA-EKMGEYFASDAGTLDAVWISEALSHFPNKALFFQNAFKVLKQGGKLVLADWFKGEE---------------------LNQTQFDNDIKPIED--GMLLP----------PLCTQPDYVKFATDAGL---KVFHEPKDISK--------DV-SKT--WDISWSLVQ--NPSLWAFAFSQGRDGIAFLQAFRAMRR-----------------------------------------------------------------------------------------------------------------------GYSNGS---------------------------FRYAVMSFQNREQSYPTSIDISRPQPPPPPAHLLSSGPVRSDPSKLMAAYPQPRNQRGSELGILVPPRMNVGEVRISKTENRINGWSPDA   [416]
'gi|87301870|ref|ZP 01084704.1| probable sterol-C-methyltransferase [Synechococcus sp. WH 5701] >gi|87283438|gb|EAQ75393.1| prob'     ------------------------------------------------------------------------------------MPLPTWLPPL----------------------------------------------------------------------------------AIGAGAGLLSLALVRE-------------------------------------------------------------------------------------------------WQRRDRR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FQSTATVAEA------YDRW----TGDRL-LENLW-----GE-----------------HVHLGH------------------------Y--G------NPP-----VA--RD--FRAAKEEFVHELVRWSG-LD--------------HLPPGTR-----------LLDVGCGIGGSARTLARDY-GFD--VLGISI-SPAQVERARQLTPSG-------------------------------LS----------------CRFAVMDA-LALE--LE--DGSVQAVWSVEAGPHMPDKQRYADELLRVLAPAGQLVVADWNRRDP----------------A--DGELNGLERWVMDQLLH--QWAHP----------EFASIPSFRRNLEASPHRRAGAV-ETADWSE--------AT-LPS--WIDSILEGVRRPGAILSLGPAAVLQGLREAPTILLMHW-----------------------------------------------------------------------------------------------------------------------AFSTGM---------------------------MRFGVFRYGSSDRLVSG-------------------------------------------------------------------------   [324]
'gi|88805005|ref|ZP 01120525.1| SAM-dependent methyltransferase [Robiginitalea biformata HTCC2501] >gi|88785884|gb|EAR17053.1| S'     ------------------------------------------------------------------------------------MS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLKNSAIEAH------YYRE----RLSED-ILKRL-----GELGVDLKHVRRSDIAAVDEFHVRG-------------------------------------------------------AEVSRELAERAG-LH------------------GAK-----------LLDVGCGLGGPCRMLADEF-DCQ--VVGVDL-SGEFIRTARKLSDLV--G-------------------------LS-EK----------------TEFLQCDA-TSLP--FA--DASFDAVWTQHVQMNIERKDAFYGEISRVLKPGGKFIYYDIFKLGP-------------------------EPITYPVPWAD--NPDIS----------FLQPASHMSEILLELGM---KSQ-EKTDQTK--------KG-IEF--FERVLQKIAA---------------------------------------------------------------------SGPPKLGLNVLMGS----------------ETKV-----------------------------KITNLVNG--------LKEKK---------------------------IQLQSGCFIR--------------------------------------------------------------------------------   [275]
'gi|28804509|dbj|BAC57960.1| phosphoethanolamine N-methyltransferase [Aster tripolium]'                                    ---------------------------------------------------------------MAGVINGDEREIQKNYWVEHSVDLTVESMMLDSMASDLDKEERPEVLSLLPSYEGKRVLELGAGIGRFTGELAKTAGEVIALDFIESVVKKNESINGHCKNVKFMCADVTSPDLRFPAESIDLIFSNWLLMYLSDKEVEDIAERFLKWVKVGGHIFFRESCFHQSGDHKRKQNPTHYREPRFYTKAFKQCHMTDASGNSYELSLI---------GSKCIGAYVRSKKNQTQICWIWQKVAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEDDRGFQQF------LDNGQYKSSGILR-YERIF-----GP----------------GFVSTGG-------------------------------------------------------LDPTKEFGALLD-LK-----------------PGQK-----------VLDVGCGIGGGDFYMADNF-DVD--VIGIDL-SVNMIAFALERSI----G-------------------------LQ-CS----------------VEFEVADC-TKKS--YP--DNSFDVIYSRDTILHIQDKPALFRTFYKWLKPGGKVLISDYCRKSG---------------------KPSEDFAEYIKQRGY-----------------DLHDVETYGKMLKDAGF---GEV-IAEDRTK--------QF-IEV--LQRELERVEKEKEEFIQ--------------------------------------------------------------------------------------------DFTE-----------------------------GDYNDIVGGWKAKLVRTGSGE---------------------------QRWGLFIAKKK-------------------------------------------------------------------------------   [493]
lcl|Smo_SMT1_7_1_unnamed_protein_product                                    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGEIEEF------YDEG------CVV-YEAVW-----GE-----------------HMHSGY------------------------FE-A------GKP---------GD--FRVAQVRMIEEVLSWAG-VP------------NDEQSRPRD-----------ILDVGCGFGGTSRYLFKKY-SAN--VKGIAL-SDYEIARAKAIAREE--G-------------------------VS-DK----------------VTFQVANA-LNQP--FE--DGQFDLVWCMECAVHIEDKLKLIAEMARVTKPEG?-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [161]
'gi|42571805|ref|NP 973993.1| S-adenosylmethionine-dependent methyltransferase/ methyltransferase/ phosphoethanolamine N-methylt'     ----------------------------------------------------------------MATPYKEERDIQKSYWMEHSSDLTVEAMMLDSKASDLDKEERPEVLSLIPPYEGKSVLELGAGIGRFTGELAQKAGEVIALDFIESAIQKNESVNGHYKNIKFMCADVTSPDLKIKDGSIDLIFSNWLLMYLSDKEVELMAERMIGWVKPGGYIFFRESCFHQSGDSKRKSNPTHYREPRFYTKVFQECQTRDASGNSFELSMV---------GCKCIGAYVKNKKNQNQICWIWQKV-S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VENDKDFQRF------LDNVQYKSSGILR-YERVF-----GE----------------GYVSTGG-------------------------------------------------------FETTKEFVAKMD-LK-----------------PGQK-----------VLDVGCGIGGGDFYMAENF-DVH--VVGIDL-SVNMISFALERAI----G-------------------------LK-CS----------------VEFEVADC-TTKT--YP--DNSFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLITDYCRSAE---------------------TPSPEFAEYIKQRGY-----------------DLHDVQAYGQMLKDAGF---DDV-IAEDRTD--------QF-VQV--LRRELEKVEKEKEEFIS--------------------------------------------------------------------------------------------DFSE-----------------------------EDYNDIVGGWSAKLERTASGE---------------------------QKWGLFIADKK-------------------------------------------------------------------------------   [491]
'gi|15221909|ref|NP 175293.1| S-adenosylmethionine-dependent methyltransferase/ methyltransferase/ phosphoethanolamine N-methylt'     --------------------------------------------------------------------------------MEHSSDLTVEAMMLDSKASDLDKEERPEVLSLIPPYEGKSVLELGAGIGRFTGELAQKAGEVIALDFIESAIQKNESVNGHYKNIKFMCADVTSPDLKIKDGSIDLIFSNWLLMYLSDKEVELMAERMIGWVKPGGYIFFRESCFHQSGDSKRKSNPTHYREPRFYTKVFQECQTRDASGNSFELSMV---------GCKCIGAYVKNKKNQNQICWIWQKV-S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VENDKDFQRF------LDNVQYKSSGILR-YERVF-----GE----------------GYVSTGG-------------------------------------------------------FETTKEFVAKMD-LK-----------------PGQK-----------VLDVGCGIGGGDFYMAENF-DVH--VVGIDL-SVNMISFALERAI----G-------------------------LK-CS----------------VEFEVADC-TTKT--YP--DNSFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLITDYCRSAE---------------------TPSPEFAEYIKQRGY-----------------DLHDVQAYGQMLKDAGF---DDV-IAEDRTD--------QF-VQV--LRRELEKVEKEKEEFIS--------------------------------------------------------------------------------------------DFSE-----------------------------EDYNDIVGGWSAKLERTASGE---------------------------QKWGLFIADKK-------------------------------------------------------------------------------   [475]
'gi|9392587|gb|AAF87203.1| sarcosine-dimethylglycine methyltransferase [Halorhodospira halochloris]'                                  ------------------------------------------------------------------------------------MATRYD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DQAIETARQY------YNSE----DADNF-YAIIW----GGE-----------------DIHIGL------------------------YN-D------------------DEEPIADASRRTVERMSSLSRQLG-----------------PDSY-----------VLDMGAGYGGSARYLAHKY-GCK--VAALNL-SERENERDRQMNKEQ--G-------------------------VD-HL----------------IEVVDAAF-EDVP--YD--DGVFDLVWSQDSFLHSPDRERVLREASRVLRSGGEFIFTDPMQADD-------------------------CPEGVIQPILD--RIHLE----------TMGTPNFYRQTLRDLGF---EEI-TFEDHTH--------QL-PRH--YGRVRRELDRREGELQG--------------------------------------------------------------------------------------------HVSA-----------------------------EYIERMKNGLDHWVNGGNKGY---------------------------LTWGIFYFRKG-------------------------------------------------------------------------------   [279]
'gi|24212080|sp|Q9C6B9|PEAM3 ARATH Putative phosphoethanolamine N-methyltransferase 3'                                    -----------------------------------------------------------------MASYGEEREIQKNYWKEHSVGLSVEAMMLDSKASDLDKEERPEILAFLPPIEGTTVLEFGAGIGRFTTELAQKAGQVIAVDFIESVIKKNENINGHYKNVKFLCADVTSPNMNFPNESMDLIFSNWLLMYLSDQEVEDLAKKMLQWTKVGGYIFFRESCFHQSGDNKRKYNPTHYREPKFYTKLFKECHMNDEDGNSYELSLV---------SCKCIGAYVRNKKNQNQICWLWQKV-S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDNDRGFQRF------LDNVQYKSSGILR-YERVF-----GE----------------GFVSTGG-------------------------------------------------------LETTKEFVDMLD-LK-----------------PGQK-----------VLDVGCGIGGGDFYMAENF-DVD--VVGIDL-SVNMISFALEHAI----G-------------------------LK-CS----------------VEFEVADC-TKKE--YP--DNTFDVIYSRDTILHIQDKPALFRRFYKWLKPGGKVLITDYCRSPK---------------------TPSPDFAIYIKKRGY-----------------DLHDVQAYGQMLRDAGF---EEV-IAEDRTD--------QF-MKV--LKRELDAVEKEKEEFIS--------------------------------------------------------------------------------------------DFSK-----------------------------EDYEDIIGGWKSKLLRSSSGE---------------------------QKWGLFIAKRN-------------------------------------------------------------------------------   [490]
'gi|71000457|dbj|BAE07178.1| phosphoethanolamine N-methyltransferase [Beta vulgaris]'                                    -------------------------------------------------------------MAASDMGVMQEREVFKKYWIEHSVDLTVEAMMLDSKASDLDKEERPEVLSMLPPYEGKSVLELGAGIGRFTGDLAKKAGQVIALDFIESAIKKNECVNGHYKNVKFMCADVTSPSLNISPNSVDIIFSNWLLMYLSDEEVQRLVERMLKWLKPGGYIFFRESCFHQSGDHKRKSNPTHYREPRFYNKVFKECHMLDESGNPYELSLI---------GCKCIGAYVKNKKNQNQIGWLWQKV-D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEDDKGFQRF------LDSSQYKCNSILR-YERVF-----GP----------------GYVSTGG-------------------------------------------------------FETTKEFVSKLD-LK-----------------PGQK-----------VLDAGCGIGGGDFYMAENF-DVE--VVGIDL-SINMISFALERSI----G-------------------------LK-CA----------------VEFEVADC-TKKP--YP--EQSFDVIYSRDTILHIQDKPALFRNFYKWLKPGGKVLISDYCKSSG---------------------PPSAEFAMYIKQRGY-----------------DLHDVEAYGQMLKDAGF---VDV-IAQDKTD--------QF-IQV--LQKELDSLEKEKDKFIA--------------------------------------------------------------------------------------------DFSE-----------------------------GDYNDIVDGWKAKLIRTKVGE---------------------------QRWGLFIANKK-------------------------------------------------------------------------------   [494]
'gi|71675069|ref|ZP 00672815.1| similar to Cyclopropane fatty acid synthase and related methyltransferases [Trichodesmium erythr'     ------------------------------------------------------------------------------------M---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TEAVTIAQKY------YDST----ETDKL-YAAIW----GGE-----------------HIHYGI------------------------YT-R------------------PDEPIHDASLSTVKTIAQTLKKID-----------------QNSR-----------VIDLGAGYGGAARYLAKTY-GCS--VCCLNL-SQLQNQRNGQLNQEQ--N-------------------------LD-PL----------------VEITQGSF-EDIP--YP--NNSFDIVWSQDAILHSGDRCLVFQEIKRILKPGGEFIFTDPMESET-------------------------FPPGALQTAFD--RLGIS----------DMGSYRFYSQTLKDLGF---EEL-NFIDLSQ--------NV-AIH--YRRFREEVQKRYNEVVK--------------------------------------------------------------------------------------------LTST-----------------------------EFVDKTLDSIQPWIERYEQGY---------------------------MQWAILHFRLLEKN----------------------------------------------------------------------------   [277]
'gi|15219502|ref|NP 177501.1| S-adenosylmethionine-dependent methyltransferase/ methyltransferase/ phosphoethanolamine N-methylt'     MVGEEDSERAQSSKMEIERESNLGSASVLMQSKVISVSNFFSIHRFHYPREKIVSFLFPSVFSRIMASYGEEREIQKNYWKEHSVGLSVEAMMLDSKASDLDKEERPEILAFLPPIEGTTVLEFGAGIGRFTTELAQKAGQVIAVDFIESVIKKNENINGHYKNVKFLCADVTSPNMNFPNESMDLIFSNWLLMYLSDQEVEDLAKKMLQWTKVGGYIFFRESCFHQSGDNKRKYNPTHYREPKFYTKLFKECHMNDEDGNSYELSLV---------SCKCIGAYVRNKKNQNQICWLWQKV-S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDNDRGFQRF------LDNVQYKSSGILR-YERVF-----GE----------------GFVSTGG-------------------------------------------------------LETTKEFVDMLD-LK-----------------PGQK-----------VLDVGCGIGGGDFYMAENF-DVD--VVGIDL-SVNMISFALEHAI----G-------------------------LK-CS----------------VEFEVADC-TKKE--YP--DNTFDVIYSRDTILHIQDKPALFRRFYKWLKPGGKVLITDYCRSPK---------------------TPSPDFAIYIKKRGY-----------------DLHDVQAYGQMLRDAGF---EEV-IAEDRTD--------QF-MKV--LKRELDAVEKEKEEFIS--------------------------------------------------------------------------------------------DFSK-----------------------------EDYEDIIGGWKSKLLRSSSGE---------------------------QKWGLFIAKRN-------------------------------------------------------------------------------   [555]
'gi|28436074|dbj|BAC57432.1| phosphoethanolamine N-methyltransferase [Suaeda japonica]'                                    -------------------------------------------------------------MAASGMELMQERDVFKKYWVEHTVDLTIEAMMLDSQASDLDKEERPEILSMLPPLEGKCLLELGAGIGRFTGELAEKAGQVIALDFIESAIKKNEVINGHYKNVKFMCADVTSPTLSFPPHSLDVIFSNWLLMYLSDEEVENLVERMLKWLKPGGYIFFRESCFHQSGDHKRKSNPTHYREPRFYTKAFKECHLQDGSGNSYELSLL---------SCKCIGAYVRNKKNQNQISWLWQKV-D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKDDKGFQRF------LDTSQYKCNSILR-YERVF-----GP----------------GYVSTGG-------------------------------------------------------YETTKEFVSMLD-LK-----------------PGQK-----------VLDVGCGIGGGDFYMAETF-DVE--VVGFDL-SVNMISFALERSI----G-------------------------LK-CA----------------VEFEVADC-TKIN--YP--DNSFDVIYSRDTILHIQDKPALFRSFYKWLKPGGKVLISDYCKKAG---------------------PPSPEFAAYIKQRGY-----------------DLHDVKEYGQMLKDAGF---VDV-LAEDRTE--------QF-IRV--LRKELETVEKEKDVFIS--------------------------------------------------------------------------------------------DFSE-----------------------------EDYNDIVGGWNDKLRRTAKGE---------------------------QRWGLFVAKKK-------------------------------------------------------------------------------   [494]
'gi|11993696|gb|AAG42853.1| SnogM [Streptomyces nogalater]'                                    ------------------------------------------------------------------------------------MTNS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GTRPQEVADF------YDGS----S--RL-IAELN-----GG-----------------SLHFGC------------------------W--D------SLPADAG---------MDRASQRLTEMMTERIE-VG-----------------PGQR-----------VLDIGCGTGAPAVQLARAT-GAE--VVGITI-SPEQVRLATAHAERE--G-------------------------VA-ER----------------VTFRCADASAELP--FP--ADSFDAVWFFESIFHLPDRLTALRRAAEVLRPGGRLALTDVLHNDE----------------------TSPAAQESLDEHAY--TPLVG----------EPMRLSDYPPLLRQARL---VPV-ECRDISE--------LTVGRT--LECMHRTLD----------------------------------------------------------------------------------------------------------------------------------------------------ENRERFVERYGS--ELVDQFSTAVPLLDAVE--FGYGIVTAARPDH-----------------------------------------------------------------------------   [278]
'gi|12324209|gb|AAG52075.1| putative S-adenosyl-methionine-sterol-C-methyltransferase, 5'' partial; 1-1344 [Arabidopsis thaliana]'    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NSYELSLV---------SCKCIGAYVRNKKNQNQICWLWQKV-S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDNDRGFQRF------LDNVQYKSSGILR-YERVF-----GE----------------GFVSTGG-------------------------------------------------------LETTKEFVDMLD-LK-----------------PGQK-----------VLDVGCGIGGGDFYMAENF-DVD--VVGIDL-SVNMISFALEHAI----G-------------------------LK-CS----------------VEFEVADC-TKKE--YP--DNTFDVIYSRDTILHIQDKPALFRRFYKWLKPGGKVLITDYCRSPK---------------------TPSPDFAIYIKKRGY-----------------DLHDVQAYGQMLRDAGF---EEV-IAEDRTD--------QF-MKV--LKRELDAVEKEKEEFIS--------------------------------------------------------------------------------------------DFSK-----------------------------EDYEDIIGGWKSKLLRSSSGE---------------------------QKWGLFIAKRN-------------------------------------------------------------------------------   [295]
'gi|17224292|gb|AAL36933.1| gamma-tocopherol methyltransferase [Perilla frutescens]'                                    ------------------------------------------------------------------------------------MAEAVTPGIC------TTGWRRGGVHAPTYNISIKPATALLVGCTTKTKSITSFSTDSL-----------RTRGRA-RRPTMSLN--------------------------------------------------------------------------AAAAEMETEM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETLRKGIAEF------YDES------SGV-WENIW-----GD-----------------HMHHGF------------------------YE-P------AAD-----VSI-SD--HRAAQIRMIEESLRFAS-FS-----------PITTTEKPKN-----------IVDVGCGIGGSSRYLARKY-GAKL-SRAITLSSPVQAQRAQQLADAQ--G-------------------------LN-GK----------------VSFEVADA-LNQP--FP--EGKFDLVWSMESGEHMPDKKKFVNELVRVAAPGGRIIIVTWCHRDL----------------SPSEESLRQEEKDLLNKICS--AYYLP----------AWCSTADYVKLLDSLSM---EDI-KSADWSD--------HV-APF--WPAVIKSAL--TWKGITSLLRSGWKTIRGAMVMPLMIE-----------------------------------------------------------------------------------------------------------------------GYKKGV---------------------------IKFAIITCRKPAS-----------------------------------------------------------------------------   [369]
'gi|68549168|ref|ZP 00588635.1| UbiE/COQ5 methyltransferase [Pelodictyon phaeoclathratiforme BU-1] >gi|68244017|gb|EAN26211.1| U'     ------------------------------------------------------------------------------------MSGNRL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVTIGNVSEV------YDGP----G--GILWEMLM-----GE-----------------QIHVGG-------------------------------------------------------EHETDILAQKAG-VS-----------------ADSH-----------LLDVCSALGAPARQLAQTY-GCR--VTGLDA-TQRMHAEAIRRTKEA--G-------------------------LD-DK----------------VEFKLGNA-LDMP--FR--ANTFDVVWGQDAWCYITDKKRLIDECARVLKPGGILAVTDWLETGS----------------M---------TKDEWDALHS--FMVFP----------YMETLEGYATLAETAGL---TII-EKEDLTP--------DF-SRY--VQIYLEKVQ---------------------------------------------------------------------------NEFRQGILD----------------NYGQ-----------------------------EMYDGVEHGITLWRDASVAGK---------------------------VGRGRLIARK--------------------------------------------------------------------------------   [264]
'gi|56692311|dbj|BAD80838.1| phosphoethanolamine N-methyltransferase [Atriplex nummularia]'                                    -------------------------------------------------------------MAASAMGVNEEREVFKKYWVEHSVDLTVEAMMLDSQASDLDKEERPEVLSMLPPYEGKSVLELGAGIGRFTGELAEKAGQVIALDFIESVIKKNECINGHYKNVKFMCADVTSPSLNISPNSVDIIFSNWLLMYLSDEEVERLVERMLKWLKPGGYIFFRESCFHQSGDHKRKSNPTHYREPRFYTKVFKECHMTDESGNSYELSLIRCKCIGAYVRCKCIGAYVRSKKNQNQISWLWQKV-D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEDDKGFQKF------LDSSQYKFNSILR-YERVF-----GP----------------GYVSTGG-------------------------------------------------------VETTKEFVSKLD-LK-----------------PGQK-----------VLDVGCGIGGGDFYMAENY-DVE--VVGIDL-SINMISFALERSI----G-------------------------LK-CA----------------VEFEVADC-TKKD--YP--ENSFDVIYSRDTILHIQDKPALFRSFLKWLKPGGKVLISDYCKSAV---------------------PPSSEFAAYIKQRGY-----------------DLHDVKAYGQMLKDAGF---IEV-IAEDRTD--------QF-IKV--LQRELDALETEKDEFIA--------------------------------------------------------------------------------------------DFSE-----------------------------QDYNDIVDGWKAKLVRTKGDE---------------------------QRWGLFIAKKK-------------------------------------------------------------------------------   [503]
'gi|7407189|gb|AAF61950.1| phosphoethanolamine N-methyltransferase [Spinacia oleracea] >gi|24212082|sp|Q9M571|PEAMT SPIOL Phosph'     -------------------------------------------------------------MAASAMGVLQEREVFKKYWIEHSVDLTVEAMMLDSQASDLDKVERPEVLSMLPPYEGKSVLELGAGIGRFTGELAEKASQVIALDFIESVIKKNESINGHYKNVKFMCADVTSPSLNISPNSVDIIFSNWLLMYLSDEEVERLVERMLKWLKPGGYIFFRESCFHQSGDHKRKSNPTHYREPRFYTKIFKECHMQDDSGNSYELSLI---------GCKCIGAYVKSKKNQNQISWLWQKV-D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEDDKGFQRF------LDSSQYKFNSILR-YERVF-----GP----------------GYVSTGG-------------------------------------------------------LETTKEFVSKLD-LK-----------------PGQK-----------VLDVGCGIGGGDFYMAENY-DVE--VVGIDL-SINMISFALERSI----G-------------------------LK-CA----------------VEFEVADC-TKKD--YP--ENSFDVIYSRDTILHIQDKPALFRSFHKWLKPGGKVLISDYCKSAG---------------------TPSAEFAAYIRQRGY-----------------DLHDVKAYGKMLKDAGF---VEV-IAENRTD--------QF-IQV--LQKELDALEQEKDDFID--------------------------------------------------------------------------------------------DFSE-----------------------------EDYNDIVDGWKAKLVRTTEGE---------------------------QQWGLFIAKKM-------------------------------------------------------------------------------   [494]
'gi|88712844|ref|ZP 01106929.1| SAM-dependent methyltransferase [Flavobacteriales bacterium HTCC2170] >gi|88708742|gb|EAR00977.1'     ------------------------------------------------------------------------------------M---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TDKLSAIEEH------YYRH----DLYDD-IINRL-----KNLNVDLNQVNRSDIAGVDEFHVRG-------------------------------------------------------AAISRELAQLAN-IK------------------NSK-----------VLDVGCGLGGPCRMLADEF-NCT--TTGIDL-SEEFINAASKLSDLV--G-------------------------LS-DS----------------TQFIYGNA-NDLP--FE--DKTFDVVWTQHVQMNVDDKKKFYSEIARVLKNDGFFIYYDIFRKGK-------------------------EKVKYPMPWAH--ESKIS----------FLEPSSTMQSILEKLGM---KKE-HSNDQTQ--------NG-IVF--FEKLISKLVA---------------------------------------------------------------------QGPPKLGLNVLMGE----------------NTIE-----------------------------KITNLLNG--------LKENK---------------------------LTLQSGIYRK--------------------------------------------------------------------------------   [274]
'gi|56678845|gb|AAV95511.1| conserved domain protein [Silicibacter pomeroyi DSS-3] >gi|56697108|ref|YP 167471.1| hypothetical pr'     ------------------------------------------------------------------------------------MSQSSECARPHRRGFDFCASAVFLCTQRAQSVGGCAMRGCPLLLWRPETCQNPAPFCRGFAAQGFTAVSVVSRAVTKTTFFDENLIERVLWQFTMKEQRANAIPATCRYARYSANPTPTPRPVKINESDRT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNFEEKIATH------YGHG----NLTAA-IRSGL-----QAQGITPEQASVEDLGPVDEFHIGG-------------------------------------------------------RAATVHFFDQID-LS-----------------ETSK-----------ALDIGCGLGGAARYAAHSF-GSQ--IEGIDL-TPEYVETGGALCQWV--G-------------------------LS-DK----------------VNLSVASA-LSMP--FE--SGDFDIAYMMHVGMNIEDKRALFKEVARVLKPGGTFAIYDIMRSND-------------------------EDLVYPVPWAS--SAETC----------CLAGPATYRAALEEGGF---VVR-QENDRRD--------FA-IDF--FEKMKKANA--------------------------------------------------------------------GQKSPPPLGLHVLMQQ----------------TTAE-----------------------------KIPNMIAN--------LQAGR---------------------------IKPVEIYAVKQ-------------------------------------------------------------------------------   [407]
'gi|62115031|gb|AAX63740.1| gamma tocopherol methyltransferase [Medicago truncatula]'                                    ------------------------------------------------------------------------------------MKITI--------------------------------------HHHTYMSCSNKRNPILVVVVSCVP---KLRFNSNSKNCALFF--------------------------------------------------------------------------CCIARCTVAS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNTQHNITMV------VTTT----RISSL-LHCTH-----TF-----------------PQHHRD------------------------TIIT------TTT-----TTLNSR--RRKGSLRVSMAAVKEVM-VVMEEEEKKKLQLE-DQSKWPKS-----------VVDVGCGIGGSSRYLAKKF-GAN--CVGITL-SPVQAERANALAAAQ--G-------------------------LA-DK----------------VSFQVADA-LQQP--FP--DGQFDLVWSMESGEHMPNKPKFVGELARVAAPGGTIIIVTWCHRDL----------------RPDEESLQQWEKDLLKKICD--SFYLP----------EWCSTADYVKLLETMSL---QDI-KSADWSP--------FV-APF--WPAVIRSAL--TWKGFTSILRSGLKTIKGALAMPLMIE-----------------------------------------------------------------------------------------------------------------------GFRKGV---------------------------IKFAIITCRKPENADGQ-------------------------------------------------------------------------   [362]
'gi|21647759|gb|AAM72970.1| methyltransferase, UbiE/COQ5 family [Chlorobium tepidum TLS] >gi|21674563|ref|NP 662628.1| methlytra'     ----------------------------------------------------------MLKSWQLLKSFHCRSNSFINQEREVFMAKYKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVNIANVNEV------YDGA----G--GILWEMLM-----GE-----------------QIHVGA-------------------------------------------------------EAETDVLARKAG-VT-----------------AETH-----------LLDVCSALGGPARYLAKNY-GCR--VTGLDA-TQRMHAEAIRRTIEA--G-------------------------LS-GK----------------IDYVLGNA-LDMP--FP--ASSFDVVWGQDAWCYITDKQRLIGECARVLKPGGVLAFTDWLEAGP----------------M---------TDEELTALNT--FMVFP----------YMETLDGYAMLAEQAGL---TVI-EKEDLTP--------DF-AAH--VQGYLDMVQ---------------------------------------------------------------------------NQYRQAIVD----------------NYGQ-----------------------------EMYDAVEQGIMLWRDASAAGK---------------------------VGRGRLVARK--------------------------------------------------------------------------------   [290]
'gi|36786423|emb|CAE15476.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii TTO1] >gi|37526990|ref|NP 930334'     ------------------------------------------------------------------------------------MTMQT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSSSAGTGFYERAFGSFSAE----AVSEV-RKETY-----GE-----------------DLGQNN------------------------WS-S---------------------------ADEFRKFSQWLQ-LS-----------------DSSH-----------VLDVCSGSGGPALFLARTS-GCS--VTGVDI-HPHGLLTARQLAADF--G-------------------------LE-DR----------------SNFVDSDVRQPLP--FP--DGTFDALWCIDSVIHIPDRLALLREWCRLLKPGGRFLYTDPTLVTG----------------------MLSKDEIMIRGMPGYF---------------LYSPLGLNERLISEAGL---CLE-RQVDLTQ--------SV-VEL--SERWRAGREKRREQFIAIEGE-------------------------------------------------------------------------------------------------------------------------EAFERMQNFLSTTQLVSIERR---------------------------LSRVAFIGYRP-------------------------------------------------------------------------------   [274]
'gi|4106538|gb|AAD02882.1| gamma-tocopherol methyltransferase [Arabidopsis thaliana]'                                    ------------------------------------------------------------------------------------MKATLAA--------------------------PSSLTSLPYRTNSSFGSKSSLLFRS------------PSSSSSVSMTTTRGN--------------------------------------------------------------------------VAVAAAATST---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EALRKGIAEF------YNET------SGL-WEEIW-----GD-----------------HMHHGF------------------------YD-P------DSS-----VQL-SDSGHKEAQIRMIEESLRFAG-VT-----------DEEEEKKIKK-----------VVDVGCGIGGSSRYLASKF-GAE--CIGITL-SPVQAKRANDLAAAQ--S-------------------------LS-HK----------------ASFQVADA-LDQP--FE--DGKFDLVWSMESGEHMPDKAKFVKELVRVAAPGGRIIIVTWCHRNL----------------SAGEEALQPWEQNILDKICK--TFYLP----------AWCSTDDYVNLLQSHSL---QDI-KCADWSE--------NV-APF--WPAVIRTAL--TWKGLVSLLRSGMKSIKGALTMPLMIE-----------------------------------------------------------------------------------------------------------------------GYKKGV---------------------------IKFGIITCQKPL------------------------------------------------------------------------------   [348]
'gi|27448218|gb|AAO13806.1| gamma-tocopherol methyltransferase [Brassica oleracea]'                                    ------------------------------------------------------------------------------------MKATLAP--------------------------PSSLISLPRHKVSSLRSPSLLLQSQ------------RPSSALMTTTATRGSV-------------------------------------------------------------------------AVTAAATSSA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EALREGIAEF------YNET------SGL-WEEIW-----GD-----------------HMHHGF------------------------YD-P------DSS-----VQL-SDSGHREAQIRMIEESLRFAG-VT-------------EEEKKIKR-----------VVDVGCGIGGSSRYIASKF-GAE--CIGITL-SPVQAKRANDLAAAQ--S-------------------------LS-HK----------------VSFQVADA-LDQP--FE--DGIFDLVWSMESGEHMPDKAKFVKELVRVTAPGGRIIIVTWCHRNL----------------SQGEESLQPWEQNLLDRICK--TFYLP----------AWCSTSDYVELLQSLSL---QDI-KCADWSE--------NV-APF--WPAVIRTAL--TWKGLVSLLRSGMKSIKGALTMPLMIE-----------------------------------------------------------------------------------------------------------------------GYKKGV---------------------------IKFGIIACQKPL------------------------------------------------------------------------------   [347]
'gi|22208517|gb|AAM94332.1| putative gamma-tocopherol methyltransferase [Sorghum bicolor]'                                    ------------------------------------------------------------------------------------M---------------------------------------------------------------------------------------------------------------------------------------------------------------ASAAVPAAT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLKEDIAGL------YDES------SGV-WERIC-----GE-----------------HLHHGF------------------------YEPA------GDA-----TAVRPD--VRRAQIRTIDEALAFAA-VP------------DDLEKRPKT-----------IVDVGCGIGGSSRYLARKY-GAQ--CTGITL-SPVQAERGNALTAAQ--G-------------------------LS-DQ----------------VSLQVADA-LEQP--FP--DGMFDLVWSMESGEHMPDKRKFVSELARVAAPGGTIIIVTCCHRNL----------------NPSETSLKPDEQRLLKRISD--AYCLA----------DWFLPSDYVSIAKSLSL---EDI-RTADWSE--------NV-VPF--WPAVIKLSL--SWKGLTSALTCGWKTINGAMGILLLIQ-----------------------------------------------------------------------------------------------------------------------GYRKGL---------------------------IKFTVITCRKPGPP----------------------------------------------------------------------------   [302]
'gi|21592747|gb|AAM64696.1| gamma-tocopherol methyltransferase [Arabidopsis thaliana]'                                    ------------------------------------------------------------------------------------MKATLAA--------------------------PSSLTSLPYRTNSSFGSKSSLLFRS------------PSSSSSVSMTTTRGN--------------------------------------------------------------------------VAVAAAATST---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EALRKGIAEF------YNET------SGL-WEEIW-----GD-----------------HMHHGF------------------------YD-P------DSS-----VQL-SDSGHKEAQIRMIEESLRFAG-VT-----------DEEEEKKIKK-----------VVDVGCGIGGSSRYLASKF-GAE--CIGITL-SPVQAKRANDLAAAQ--S-------------------------LS-HK----------------ASFQVADA-LDKP--FE--DGKFDLVWSMESGEHMPDKAKFVKELVRVAAPGGRIIIVTWCHRNL----------------SAGEEALQPWEQNILDKICK--TFYLP----------AWCSTDDYVNLLQSHSL---QDI-KCADWSE--------NV-APF--WPAVIRTAL--TWKGLVSLLRSGMKSIKGALTMPLMIE-----------------------------------------------------------------------------------------------------------------------GYKKGV---------------------------IKFGIITCQKPL------------------------------------------------------------------------------   [348]
;
END;


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END;


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