#NEXUS 
[MacClade 4.08 registered to Tomoaki Nishiyama, National Institute for Basic Biology]


BEGIN DATA;
	DIMENSIONS  NTAX=76 NCHAR=1869;
	FORMAT DATATYPE=PROTEIN  SYMBOLS = " 1 2 3 4"  MISSING=? GAP=- ;
MATRIX
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'gi|15218666|ref|NP 171796.1| WEE1; ATP binding / kinase/ protein kinase/ protein serine/threonine kinase/ protein-tyrosine kina'    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFEKNGRTLLAKRKTQGTIKTRASKKIRKMEGTLE------RHSLLQFGQLSKISF-------ENRPSSNVAS-----S-AFQGLLDS---DSSELRNQLG--------SADSDANCGEKDFILSQDFFCTPDYITPDNQNLMSGL-DISKDH-SPCP---------RSPV-----------------------------------------------------------------------------------------------------------------------------KLNTVKSKRCRQESFTGNHSNSTWSSKHRVDEQE----------NDDIDTDEVMGDK-LQANQTERTGYVS------------------------------------------------------------------------------------------------------------------QAA-----VALRC--------------------RAMPPPCL--KNPYVLNQSETATD----------------------------------------------------------------------------PFGHQ------------------------------------------------------RSKCASFLPVSTSGDGLSRYLTDFHEIRQIGAGHFSRVFKVLKRMDGCLYAVKHSTRKLYLDSER------------------------------RKAMMEVQALAALG-------------------------------------------FHENIVGYYSSWFE----NEQLYIQLELCDH-------SLSALPKKSSLKVSE--REILVIMHQ---------------------IAKALHFVHEKGIAHLDVKPDNIYI----------------KNG-------------------------------------------------VCKLGDFGCATRLDKS----L----------------PVEEGDARYMPQEILN--ED-Y---EHLDKVDIFSLGVTVYELIKGSPLTESRNQSLNIKEG-KLPLLPG-------HSLQ-------LQQLLKTMMDRDPKRRPSAREL--------LDHPMFDR--IRG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [500]
'gi|6056405|gb|AAF02869.1| Similar to Wee1 protein kinase [Arabidopsis thaliana]'                                    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFEKNGRTLLAKRKTQGTIKTRASKKIRKMEGTLE------RHSLLQFGQLSKISF-------ENRPSSNVAS-----S-AFQGLLDS---DSSELRNQLG--------SADSDANCGEKDFILSQDFFCTPDYITPDNQNLMSGL-DISKDH-SPCP---------RSPV-----------------------------------------------------------------------------------------------------------------------------KLNTVKSKRCRQESFTGNHSNSTWSSKHRVDEQE----------NDDIDTDEVMGDK-LQANQTERTGYVS------------------------------------------------------------------------------------------------------------------QAA-----VALRC--------------------RAMPPPCL--KNPYVLNQSETATD----------------------------------------------------------------------------PFGHQ------------------------------------------------------RSKCASFLPVSTSGDGLSRYLTDFHEIRQIGAGHFSRVFKVLKRMDGCLYAVKHSTRKLYLDSER------------------------------RKAMMEVQALAALG-------------------------------------------FHENIVGYYSSWFE----NEQLYIQLELCDH-------SLSALPKKSSLKVSE--REILVIMHQ---------------------IAKALHFVHEKGIAHLDVKPDNIYI----------------KNG-------------------------------------------------VCKLGDFGCATRLDKS----L----------------PVEEGDARYMPQEILN--ED-Y---EHLDKVDIFSLGVTVYELIKGSPLTESRNQSLNIKEG-KLPLLPG-------HSLQ-------LQQLLKTMMDRDPKRRPSAREL--------LDHPMFDR--IRGHTMVEWLKAKQNGEIFTVV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [519]
'gi|42362341|gb|AAS13373.1| wee1 [Glycine max]'                                    ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGKSQSQRIGKKSRKMKGALNTHTNTTRHLQLQLGQVSLIPL--------QQPSSTTATTSSAVS-CFQNLLDAEAPNASSSRVALI--------DNAAAAAADDRDCILSQDFFCTPDYITPDNQNVFNGF-DCDREN-TPCP---------KSPE-----------------------------------------------------------------------------------------------------------------------------KLNTTKSKRCRPDAMSVHPLSPTFCSDHQPVVEL----------GKDSGTEELALEKTIAPGKPKAQNYVS------------------------------------------------------------------------------------------------------------------HSA-----VALRC--------------------RVMPPPCF--RNPYLKDVSDKDLD----------------------------------------------------------------------------PFGNQ------------------------------------------------------RLKCAGLFPAFTGGDGLSRYRADFHEIEQIGRGNFSSVFKVLKRIDGCLYAVKHSTRPLRLETER------------------------------TKALMEVQALAALG-------------------------------------------LHENIVGYYSSWFE----NEQLYIQMELCDH-------SLSI--RKYSALFTE--GQVLDALFQ---------------------VANALQFIHEKGIAHLDVKPDNIYV----------------KNG-------------------------------------------------VYKLGDFGCATLLDSS----L----------------PIEEGDARYMPQEILN--EN-Y---DHLDKVDIFSLGASIYELIRRLPLPESGCQFFNLKEG-KFPLLPG-------HSLQ-------LQNLLKVMMDPDPVKRPSAKEL--------IENPIFCR--IQRTAS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [502]
'gi|55859438|emb|CAG29372.1| protein kinase WEE1 [Lycopersicon esculentum var. cerasiforme] >gi|84574987|emb|CAJ56085.1| protein'    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERKTPNR-----------TRRKQRSNQKSKKRMNKGS-LSRHFTVGIAKPPLPNQ-------QQLHSSLSNVTLPNPS-RFQKLLDSDDLPPAQSQFSSVLPLNLDADDDADVADVAEKDFILSQDFFCTPDYLTPDAPAICNGL-DGDKDDYTPCP---------KSPE-----------------------------------------------------------------------------------------------------------------------------KLLSVSRK--RPRLASVRPFSSDLSGQQQPVDIP----------TDTFGTDEMKSEKI--SESEKGPSYVS------------------------------------------------------------------------------------------------------------------QSA-----IALRY--------------------RVMPPPCI--RNPYLGDASEIDAD----------------------------------------------------------------------------PFGNR------------------------------------------------------RSKYPGFNPAISGNDGLSRYRTDFHEIEQIGSGNFSRVFKVFKRIDGCMYAVKHSTKQLHQDTDR------------------------------RQALMEVQALAALG-------------------------------------------PHENVVGYYSSWFE----NEHLYIQMELCDH-------SLSN--KKYCKLFSE--VEVLEAMYQ---------------------VANALQFIHQRGVAHLDVKPDNIYV----------------KNG-------------------------------------------------VYKLGDFGCATLLDKS----Q----------------PIEEGDARYMPQEILN--EN-Y---DHLDKVDIFSLGAAIYELIRGSSLPESGPHFLNLREG-KLPLLPG-------HSLQ-------FQNLLKAMMDPDPTRRPSAKGV--------VDNPIFER--WQRNS-----------------------------------------------------------------------------------------------------------------------------------------------------N-----------K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [510]
'gi|50905103|ref|XP 464040.1| putative tyrosine kinase Wee1 [Oryza sativa (japonica cultivar-group)] >gi|42408835|dbj|BAD10095.1'    ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRTKTPRPRGGKSRRATAAAGKEREREREREREGRSPSGELSLQLEHVSLFSF------LADAPREGAAAARTPFT-PFEELLEGSCDPDPTPPPPLPPLQPQATPMDADEVVEEKDSGILSQDFFCTPDYITPDAPQLGSGF-DANKEN-IPCP---------NSPE-----------------------------------------------------------------------------------------------------------------------------KSV-CRSKRYKRDCSPKGLGSNDIFDSQWIAPVQ----------FEGL--DDSEEEQLKESSSHKRGSYVS------------------------------------------------------------------------------------------------------------------QSA-----VALRC--------------------RVMPPPCI--RNPYLNTDHQIDDN----------------------------------------------------------------------------VFGGR------------------------------------------------------QCKSSGFSPSV-DGDGLSRYRTDFHEIEQIGRGNFSVVFKVLKRIDGCLYAVKRSIRQLHNDRER------------------------------RQAVKEVQALAALG-------------------------------------------CHENIVGYFTSWFE----NKQLFIQMELCDR-------CLSM---DRNQPLKC--GEALELLYQ---------------------ICKGLDFIHERGIAHLDVKPDNIYV----------------RNG-------------------------------------------------VYKLGDFGCATLIDRS----L----------------AIEDGDSRYMPPEMLN--DK-Y---EHLDKVDIFSLGAAIYELIRGTQLPDSGPQFTSLREG-KIALLPG-------CPMQ-------FQSLIKSMMDPDPVRRPSAKEV--------LRHPIFDK--LHKAPAKK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [520]
'gi|5821717|gb|AAD52983.1| Wee1-like protein [Zea mays]'                                    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CTPDYITPEMPQVANEFDDDDKEN-IPCP---------KSPE-----------------------------------------------------------------------------------------------------------------------------KSANPRSKRYRTDCSPKAREVTDFSFDHQITPVL----------FDSLTRDDSEEEQPKQPALEKRGGYVS------------------------------------------------------------------------------------------------------------------QSA-----VALRC--------------------RVMPPPCV--KNPYLNTDPCIDAA----------------------------------------------------------------------------VYGGR------------------------------------------------------QCNSAVFSPSI-GGNGLSRYRTDFHEIEKIGYGNFSVVFKVLNRIDGCLYAVKRSIKQLHNDMER------------------------------RQAVKEVQAMAALG-------------------------------------------SHENIVRYFTSWFE----NEQLYIQMELCDR-------CLSM---NRNQPVKR--GEALELLYQ---------------------ICKGLDFMHERGIAHLDVKPDNIYV----------------RNG-------------------------------------------------IYKLGDFGCATLVNRS----L----------------AIEDGDSRYMPPEMLN--DK-Y---EHLDKVDIFSLGAAVYELIRGTPLPESGSHFTSIREG-KIALLPG-------CPMQ-------FQSLIKSMMDPDPVRRPSAKEI--------LRHPSFDK--LHKASSK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [403]
lcl|Smo_WEE1_10_1_unnamed_protein_product                                    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NAVLNVPVGLTPLRSKRPRSDEYLN------------------------------------------------------------------------------------------------------------------QEAENAKTLSLRQ--------------------RVMSPPCF--RNPFVNSDVFPERA---------------------------------------------------------------------------------------------------------------------------------------------RQGCVSAFGSSSRYREEFHQIKEIGRGDFSYVYKVLKRLDGCLYAVKHSNRRLLNEGDRFVTKSRDYGIDLANFSFCR-----------RKALREVQALSCL-------------------------------------------------VRYFSSWFE----NDFLYIQMELCET-------NLRD--ESLAWTFTE--KKLTEAMFQ---------------------LLNALKHLHSHGLAHLDVKPDNIYI----------------RKG-------------------------------------------------VYKIGDFGLACRIDGAI--------------------SIEDGDSRYLPMELIN--DD-H---SHLDKADMFSLGATFYELARRSPLPASGSQYQAIRQG-KLALLPG-------FSLV-------FQSLIKSLMHPAAKNRPSAAQA--------LKNALFKKS-SSKAL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [343]
lcl|Ppa_WEE1_39_1_unnamed_protein_product                                    ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?TVHTKPSWRDENM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRQSPVSI--QNPFLLEDTNLPQKMITSDEYTFVIRCELRLDYMTI---------------------------------------------------------------------------------------------------------TNLRTISNLPFVAKITEDEWEQTFISIYRHDFHEIREIGHGNFSRVFKVLKRIDGCMYAIKRSRHSLRSTVER------------------------------RQALTEVQALAAVGEFRLKLVPDFLFIFGQCHLQECCSIIFQPPVELDDEYCATNLRFHENVVRYYTAWFE----DEYCYIQTELCES-------NLTQLRDADPNVSKE--TSLLEIMRQTFSGHATLESFHDVDRISSEDMASALSAIHSKGLVHLDVKPDNIYV----------------LNG-------------------------------------------------VYKLGDFGRAVRADGSM--------------------EIEEGDARYMPLEILN--DD-H---SQLTKVDMFSLGATIYELARGLPLPTSGAQFQSLREG-KLSLLPG-------YSLT-------LQNIFKALLNPDASARPSAAEL--------LNHSVFHRG-LARVS--------------------------------------------------------------------------------------------------------------------------------------------------------------------SLDALEVTEKSL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [420]
'gi|17865613|sp|Q63802|WEE1 RAT Wee1-like protein kinase >gi|59862052|gb|AAH90346.1| Wee 1 homolog (S. pombe) (predicted) [Rattu'    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFLSRQQPPPT-RRAAAACSLRQKLIFS--------PGSDC-EEEEEEEEEGSGHSTGEDSAFQEPDSPLPSARSPAEAEAERRRRSPGAEPSSPGELEEDLLLRGGGGGAQAAGGGAEGDSW----EEEGFGSSSPV---KSPTTAYFLGSSFSPVRCGGPGDAS-------------PRGCGVPRAMDDPCSPQP-------DYPSTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSKAR-VIDSSSVKL----------RGSSLFMD----------TEKSGKREFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------TRQTPQVN--INPFTPDPVMLHSS-----------------------------------------------------------------------------GQCR--------GRKRAYFNDS-SEDM--------EASDY----------EFEDET--RP-AK--RITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHPHVVRYFSAWAE----DDHMLIQNEYCNGGSLA---DAVSENYRVMSYFTE--AELKDLLLQ---------------------VGRGLRYIHSMSLVHMDIKPSNIFI----------------SRTS--------IPNAV--------------SEEGDE------DD-WISNKVMFKIGDLGHVTRISSP---------------------QVEEGDSRFLANEVLQ--EN-Y---SHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQG-RLPRIPQ------VLSQE-------LTELLKVMIHPDPERRPSAMVL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELNAEKFKNSLLQKELKKAQMAAKVAAEERALLTDRMATRS-------TTQSNRTSRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [646]
'gi|31543956|ref|NP 033542.2| wee 1 homolog [Mus musculus] >gi|13905130|gb|AAH06852.1| Wee 1 homolog [Mus musculus] >gi|12847189'    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFLSRQQPPPT-RRVGAAYSLRQKLIFS--------PGSDC-EEEEEEEEEGSGHSTGEDSAFQEPDSPLPSARSPAEAEAERRRRSPGAEPSSPGELEDDLLLQGGGGGAQAAGGGAEGDSW----EEEGFGSSSPV---KSPSTAYFLSSPFSPVRCGGPGDAS-------------PQGCGAPRAMDDPCSPQP-------DYPSTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSKAR-VIDSGSVKL----------RGSSLFMD----------TEKSGKREFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------TRQTPQVN--INPFTPDPVLLHSS-----------------------------------------------------------------------------GRCR--------GRKRAYFNDS-SEDM--------EASDY----------EFEDET--RP-AK--RITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHPHVVRYFSAWAE----DDHMLIQNEYCNGGSLA---DAISENYRVMSYLTE--VELKDLLLQ---------------------VGRGLRYIHSMSLVHMDIKPSNIFI----------------SRTS--------IPNAV--------------SEEGDE------DD-WISNKVMFKIGDLGHVTRISSP---------------------QVEEGDSRFLANEVLQ--EN-Y---SHLPKADIFALALTVVCAAGAEPLPRNGEQWHEIRQG-RLPRIPQ------VLSQE-------VTELLRVMIHPDPERRPSAMEL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELNAEKFKNSLLQKELKKAQMAAKVAAEERALFTDRMATRS-------TTQSNRTSRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [646]
'gi|73988828|ref|XP 534051.2| PREDICTED: similar to Wee1-like protein kinase (WEE1hu) [Canis familiaris]'                            MVNYSYQRIIFAIRSEVCSEVGQSPLPTLAHVLANKYKHRGGVEGPGFGLRAGAAAVYSGGRVSGGLPRGPRPGGSKLASLGAYPTLQLPWGETEAPEAFPTAAVPASSPPGPASLLTSASPLSPGLSSQSPHVVNGRGKPRSPNLRSPDLRLDLRRPQPRCPGRPASAGQAAPLPPPPPPPPPPAAPSAPEPHPVTAQVRRRGDPARPVARGGPVPWAVRVLDSAGSGSPVLGPGPRGAMSFLSRQQPPPPRRRPGASCTLRQKLIFS--------PCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPE-RRRSPGPAPGSPGELEEDMLLRGACPGADAPGGGAEGDSW----EEEGFGSSSPV---KSPAAAYFLGSSFSPVRCGGAGDAS-------------PRGCGARRASEGPCSPLP-------DHPGTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSKAR-GIDSSSVKL----------RGGSLFMD----------TEKSGKREFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------MRQTPQVN--INPFTPDSVLLHSS-----------------------------------------------------------------------------GQCR--------RRKRTHWNDSCGEDM--------EASDY----------ELEDET--RP-AK--RITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHSHVVRYFSAWAE----DDHMLIQNEYCNGGSLA---DAISENYRSMSYFTE--AELKDLLLQ---------------------VGRGLRYIHSMSLVHMDIKPSNIFI----------------SRTS--------IPNAA--------------SEEGDE------DD-WASNKVMFKIGDLGHVTRISSP---------------------QVEEGDSRFLANEVLQ--EN-Y---THLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQG-RLPRIPQ------VLSQE-------FTELLKVMIHPDPERRPSAMAL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELNAEKFKNSLLQKELKKAQM-AKAAAEERALFTDRMTTRS-------TTQSNRTSRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [887]
'gi|55635587|ref|XP 521839.1| PREDICTED: wee1 tyrosine kinase [Pan troglodytes]'                                    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFLSRQQPPPP-RRAGAACTLRQKLIFS--------PCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPE-RRRSPGPTPGSPGELEEDLLLPGACPGADEAGGGAEGDSW----EEEGFGSSSPV---KSPAAPYFLGSSFSPVRCGGPGDAS-------------PRGCGARRAGEGRRSPRP-------DHPGTPPH-KTFRKLRLFDTP---------HTPKVAKDLPPVESGPPRACRPRVRTDNAVCEDAGGCWPGRLTLPSRMMPFKRGDRACNLGGAGRRSLKKNNCPALIS---------------------------------------------------LLSKAR-GIDSSSVKL----------RGSSLFMD----------TEKSGKREFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------VRQTPQVN--INPFTPDSLLLHSS-----------------------------------------------------------------------------GQCR--------RRKRTYWNDSCGEDM--------EASDY----------ELEDET--RP-AK--RITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHSHVVRYFSAWAE----DDHMLIQNEYCNGGSLA---DAISENYRIMSYFKE--AELKDLLLQ---------------------VGRGLRYIHSMSLVHMDIKPSNIFI----------------SRTS--------IPNAS--------------SEEGDE------DD-WASNKVIFKIGDLGHVTRISSP---------------------QVEEGDSRFLANEVLQ--EN-Y---THLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQG-RLPRIPQ------VLSQE-------FTELLKVMIHPDPERRPSAMAL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELNAEKFKNSLLQKELKKAQM-AKAAAEERALFTDRMATRS-------TTQSNRTSRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [719]
'gi|15208193|dbj|BAB63121.1| hypothetical protein [Macaca fascicularis]'                                    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MD----------TEKSGKREFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------VRQTPQVN--INPFTPDSLLLHSS-----------------------------------------------------------------------------GQCR--------RRKRTYWNDSFGEDM--------EASDY----------ELEDET--RP-AK--RITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHSHVVRYFSAWAE----DDHMLIQNEYCNGGSLA---DAISENYRIMSYFKE--AELKDLLLQ---------------------VGRGLRYIHSMSLVHMDIKPSNIFI----------------SRTS--------IPNAA--------------SEEGDE------DD-WASNKVIFKIGDLGHVTRISSP---------------------QVEEGDSRFLANEVLQ--EN-Y---THLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQG-RLPRIPQ------VLSQE-------FTELLKVMIHPDPERRPSAMAL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELNAEKFKNSLLQKELKKAQM-AKAAAEERALFTDRMATRS-------TTQNDPNFQCKFKGLWSKEKYLCMP--------------------------------------------------------------------------------------------------------------------------------------------------   [433]
'gi|76635665|ref|XP 593176.2| PREDICTED: similar to Wee1-like protein kinase (WEE1hu) isoform 1 [Bos taurus]'                        ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFLSRQQPPPP-RRAAASCTLRQKLIFS--------PCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPE-RRRSPDTIPGSPGELEEDMLLRGACPGADAAGGGAEGDSW----EEEGFGSSSPV---KSPAAPYFLGSSFSPVRCGGPGDAS-------------LRGCGARGVGEGACSPLP-------DYPGTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSKAR-GIDSSSVKL----------RGGSLFMD----------TEKSGKREFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------VRQTPQVN--INPFTPDSLLLHSS-----------------------------------------------------------------------------GQCR--------RRKRAYWNDSCGEDM--------EASDY----------EFEDET--RP-AK--RITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCVYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHSHVVRYFSAWAE----DDHMLIQNEYCNGGSLA---DAISENYRSMSYFTE--AELKDLLLQ---------------------VGRGLRYIHSMSLVHMDIKPSNIFI----------------SRTS--------IPNAA--------------SEEGDE------DD-WASNKVMFKIGDLGHVTRISSP---------------------QVEEGDSRFLANEVLQ--EN-Y---THLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQG-RLPRIPQ------VLSQE-------FTELLKVMIHPDPERRPSAMAL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELNAEKFKNSLLQKELKKAQM-AKAAAEERALFTDRMATRS-------TTQSNRTSRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [646]
'gi|9501249|emb|CAB99477.1| wee1-like CDK tyrosine kinase [Daphnia magna]'                                    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRDIEMEENHCRIAQRLEFPLSDE----EDLHEASTGNNRTSSNSSSDRLDSSGSDEG---------------------------------------------------------------------------------LGMTIRITSPRKPRFIRSR-------------------------------------AREPMSPPY-SGVRALRLFDSP---------ATPK-------------------------------------------------------------------------T---------------------------------------------------LLENSS-AIMTPVLATPAPRN-----RMRTLFTM----------SSTKSSDKKDN-------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTPPAAN--VNPFTPTGML-LTS----------------------------------------------------------------------------KKRTR--------SKRSLNGSLVNSFDE--------EVHEA----------TDESDEE-MP-PK--RIALHQTSV-PRYHKEFHEICLIGKGEFGSVHKCLNRLDGCTYAVKKSLMPVAGSPNE------------------------------RSALNEVWAHAVLG-------------------------------------------QHPHAVRYYSAWAE----NGHMIIQNEFCNSGTLE---ELIRTNQLNNVTVNE--PQLKSTLLQ---------------------IAEGLHYIHSKQLAHMDIKPGNIFI----------------CREN--------SDDCSVHHDS---------DDGFDE------LD-DDYGSVTYKIGDLGHVTSVVQP---------------------IVEEGDCRYLPVEILR--EN-Y---EHLTKADIFSLGLTIYEMAGGGQLPKNGDEWHAIRQG-RLPYNGR-------YSIE-------LHNLLELMIHPDPTLRPSTQVL--------TQHPVLGPN-GAKSK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [494]
'gi|499072|emb|CAA43979.1| Wee1 Hu [Homo sapiens]'                                    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFLSRQQPPPP-RRAGAACTLRQKLIFS--------PCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPERSPTEPGPE-RRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSW----EEEGFGSSSPV---KSPAAPYFLGSSFSPVRCGGPGDAS-------------PRGCGARRAGEGRRSPRP-------DHPGTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSKAR-GIDSSSVKL----------RGSSLFMD----------TEKSGKREFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------VRQTPQVN--INPFTPDSLLLHSS-----------------------------------------------------------------------------GQCR--------RRKRTYWNDSCGEDM--------EASDY----------ELEDET--RP-AK--RITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHSHVVRYFSAWAE----DDHMLIQNEYCNGGSLA---DAISENYRIMSYFKE--AELKDLLLQ---------------------VGRGLRYIHSMSLVHMDIKPSNIFI----------------SRTS--------IPNAA--------------SEEGDE------DD-WASNKVMFKIGDLGHVTRISSP---------------------QVEEGDSRFLANEVLQ--EN-Y---THLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQG-RLPRIPQ------VLSQE-------FTELLKVMIHPDPERRPSAMAL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELNAEKFKNSLLQKELKKAQM-AKAAAEERALFTDRMATRS-------TTQSNRTSRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [646]
'gi|228044|prf||1715335A Wee1-like gene'                                    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MD----------TEKSGKREFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------VRQTPQVN--INPFTPDSLLLHSS-----------------------------------------------------------------------------GQCR--------RRKRTYWNDSCGEDM--------EASDY----------ELEDET--RP-AK--RITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHSHVVRYFSAWAE----DDHMLIQNEYCNGGSLA---DAISENYRIMSYFKE--AELKDLLLQ---------------------VGRGLRYIHSMSLVHMDIKPSNIFI----------------SRTS--------IPNAA--------------SEEGDE------DD-WASNKVMFKIGDLGHVTRISSP---------------------QVEEGDSRFLANEVLQ--EN-Y---THLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQG-RLPRIPQ------VLSQE-------FTELLKVMIHPDPERRPSAMAL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELNAEKFKNSLLQKELKKAQM-AKAAAEERALFTDRMATRS-------TTQSNRTSRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [432]
'gi|4507917|ref|NP 003381.1| wee1 tyrosine kinase [Homo sapiens] >gi|10944890|emb|CAC14173.1| WEE1 protein [Homo sapiens] >gi|13'    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFLSRQQPPPP-RRAGAACTLRQKLIFS--------PCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPE-RRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSW----EEEGFGSSSPV---KSPAAPYFLGSSFSPVRCGGPGDAS-------------PRGCGARRAGEGRRSPRP-------DHPGTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSKAR-GIDSSSVKL----------RGSSLFMD----------TEKSGKREFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------VRQTPQVN--INPFTPDSLLLHSS-----------------------------------------------------------------------------GQCR--------RRKRTYWNDSCGEDM--------EASDY----------ELEDET--RP-AK--RITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHSHVVRYFSAWAE----DDHMLIQNEYCNGGSLA---DAISENYRIMSYFKE--AELKDLLLQ---------------------VGRGLRYIHSMSLVHMDIKPSNIFI----------------SRTS--------IPNAA--------------SEEGDE------DD-WASNKVMFKIGDLGHVTRISSP---------------------QVEEGDSRFLANEVLQ--EN-Y---THLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQG-RLPRIPQ------VLSQE-------FTELLKVMIHPDPERRPSAMAL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELNAEKFKNSLLQKELKKAQM-AKAAAEERALFTDRMATRS-------TTQSNRTSRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [646]
'gi|47123300|gb|AAH70052.1| Wee1 tyrosine kinase [Homo sapiens]'                                    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFLSRQQPPPP-RRAGAACTLRQKLIFS--------PCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPE-RRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSW----EEEGFGSSSPV---KSPAAPYFLGSSFSPVRCGGPGDAS-------------PRGCGARRAGEGRRSPRP-------DHPGTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSKAR-GIDSSSVKL----------RGSSLFTD----------TEKSGKREFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------VRQTPQVN--INPFTPDSLLLHSS-----------------------------------------------------------------------------GQCR--------RRKRTYWNDSCGEDM--------EASDY----------ELEDET--RP-AK--RITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHSHVVRYFSAWAE----DDHMLIQNEYCNGGSLA---DAISENYRIMSYFKE--AELKDLLLQ---------------------VGRGLRYIHSMSLVHMDIKPSNIFI----------------SRTS--------IPNAA--------------SEEGDE------DD-WASNKVMFKIGDLGHVTRISSP---------------------QVEEGDSRFLANEVLQ--EN-Y---THLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQG-RLPRIPQ------VLSQE-------FTELLKVMIHPDPERRPSAMAL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELNAEKFKNSLLQKELKKAQM-AKAAAEERALFTDRMATRS-------TTQSNRTSRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [646]
'gi|71041942|pdb|1X8B|A Chain A, Structure Of Human Wee1a Kinase: Kinase Domain Complexed With Inhibitor Pd0407824'                  ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAMG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHSHVVRYFSAWAE----DDHMLIQNEYCNGGSLA---DAISENYRIMSYFKE--AELKDLLLQ---------------------VGRGLRYIHSMSLVHMDIKPSNIFI----------------SRTS--------IPNAA--------------SEEGDE------DD-WASNKVMFKIGDLGHVTRISSP---------------------QVEEGDSRFLANEVLQ--EN-Y---THLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQG-RLPRIPQ------VLSQE-------FTELLKVMIHPDPERRPSAMAL--------VKHSVLLSA-SRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [289]
'gi|19716048|dbj|BAB86797.1| Wee1B kinase [Xenopus laevis]'                                    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNVQPRNMNVQPRNMNVQPVRHKLFFS-----------------DTDEEEEDGHSTGEDSAFQESDSPVSRQREKQEGKPP-------------------------------------GGTWEELEEEEGFG-SSPI---KSPGD-FFMSDSPSYRQLAPASPTR---------------------SPQGPTSPIP-------ECPGTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSKAR-GIGSSALRF----------RGGTLFRE----------AEKAPKPEF---------------------------------------------------------------------------------------------------------------------------------------------------------------------VYSTPQVN--INPFTPDSLEIQSS----------------------------------------------------------------------------AGLCR--------GRKRALLNDSCGEDM--------EGSDC----------ELEDEDI-RP-AK--RIPITESNMKSRYATEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHPHVVRYYSAWAE----DDHMLIQNEYCNGGSLS---DVISENYRTMQYFTE--PELKDLLLQ---------------------VARGLKYIHSMSLVHMDIKPSNIFI----------------SRTT--------LPNTA--------------VEEADD------EE-CGSGKVIYKIGDLGHVTRVSSP---------------------QVEEGDSRFLANEVLQ--EN-Y---THLAKADIFALALTVWSAAGAEPFPTNGDQWHEIRQG-KLPRVPQ------LLSQE-------FVDLIKLMISPDPEKRPSSVAL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELDAEKFKNALLQKELKKAQI-AKAAAEERAHFPDRIATRS-------TTQNNRTTRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [595]
'gi|6946695|emb|CAB72316.1| Wee1-like CDK Tyrosine kinase [Daphnia pulex]'                                    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRDIEMEENHCRIAQRLEFPLSDE----EDLHEASSTTDRTSSNISSDRLDSSGSDEG---------------------------------------------------------------------------------LGMTIRITSPRKPRFLRTR-------------------------------------ARESMSPPY-SGVRALRLFDSP---------ATPK-------------------------------------------------------------------------T---------------------------------------------------LLENSS-AMMTPVLATPAPRN-----RMRTLFNM----------SSAKSTDKKDN-------------------------------------------------------------------------------------------------------------------------------------------------------------------LDTPPAAN--VNPFTPTGML-LTS----------------------------------------------------------------------------KKRTR--------SKRSLNGSLVNSFDE--------EVHEA----------TDESDEE-LP-PK--RIALHQTSV-PRYHKEFHEICLIGKGEFGSVHKCLNRLDGCTYAVKKSLMPVAGSPNE------------------------------RSALNEVWAHAALG-------------------------------------------QHPHVVRYYSAWAE----NGHMIIQNEFCNSGTLE---ELIRTNQQNNVTVNE--PQLKSTLLQ---------------------IAEGLHYIHSKQLAHMDIKPGNIFI----------------CREN--------IDDCSVHHDS---------DDGFDE------LD-DDYGSVTYKIGDLGHVTSVVQP---------------------IVEEGDCRYLPVEILQ--EN-Y---DNLAKADIFSLGLTIYEMAGGGQLPKNGDEWHAIRQG-RLPYNGR-------YSIE-------LHNLLELMIHPDPTLRPSTQVL--------TQHPVLGPN-GAKSK--------------------------------------------------------------------------------------------------------------------------------------------------------------------DQLSRELNAERLKNRQLSEKLQAARHIQNLMPLSRFSLEEVPAPKM--PKLQMNEPCAARRLLLGRKM-NRSLSNADF--------------------------------------------------------------------------------------------------------------------------------------------------   [569]
'gi|22773852|gb|AAN07091.1| wee1-like kinase [Xenopus laevis]'                                    ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLQPVPHRLLFS-----------------DSD-DEEDGHSTGEDSAFQESDSPVSRLREKQEG--P-------------------------------------GGSW---EEEEGLG-SSPI---KSPGH-FFMCDSPTYRDLPPA-------------------------SPPGPAASPP-------DCPGTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSKAR-GIGSSALRF----------RGGTLFRE----------AEKLPKPEF---------------------------------------------------------------------------------------------------------------------------------------------------------------------TYSTPQVN--INPFTPDSLEIQSS----------------------------------------------------------------------------TGLCR--------RRKRALLNDSCGEDM--------EGSDC----------ELEDEDV-RP-AK--RIPITESNMKSRYATEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPMAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHPHVVRYYSAWAE----DDHMLIQNEYCNGGSLA---DAISENYRTMQYFTE--PELKDLLLQ---------------------VARGLKYIHSMSLVHMDIKPSNIFI----------------SRIT--------VPNTG--------------VEEGDD------ED-CGSGNVVYKIGDLGHVTRVSSP---------------------QVEEGDSRFLANEVLQ--ED-Y---THLAKADIFALALTVWCAAGAEPFPTNGDQWHEIRQG-KLPRVPQ------LLSQE-------FVDLIKLMISPDSEKRPSSMAL--------VKHSVLLSA-SRKNA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELNAEKFKNALLQKELKKAQI-AKAAAEERALFPDRIATRS-------TTQSNRTTRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [571]
'gi|893391|dbj|BAA06404.1| wee1 kinase [Mus musculus]'                                    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFLSRQQPPPT-RRVGAAYSLRQKLIFS--------PGSDC-EEEEEEEEEGSGHSTGEDSAFQEPDSPLPSARSPAEAEAQRRRRSPGAEPSSPGELEDDLLLQGGGGGAQAAGGGAEGDSW----EEEGFGSSSPV---KSPSTAYFLSSPFSPVRCGGPGDAS-------------PQGCGAPRAMDDPCSPQP-------DYPSTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSKAR-VIDSGSVKL----------RGSSLFMD----------TEKSGKREFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------TRQTPQVN--INPFTPDPVLLHSS-----------------------------------------------------------------------------GRCR--------GRKRAYFNDS-SEDM--------EASDY----------EFEDET--RP-AK--RITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHPHVVRYFSAWAE----DDHMLIQNEYCNGGSLA---DAISENYRVMSYLTE--VELKDLLLQ---------------------VGRGLRYIHSMSLVHMDIKPSNIFI----------------SRTS--------IPNAV--------------SEEGDE------YD-WISNKVMFKIGDLGHDTRISSP---------------------QLEEGDSRFLANEVLQ--EN-Y---SHLPKADIFALALTVVCAAGAEPLPRNGEHWHEIRQG-RLPRIPQ------VLSQE-------VTELLRVMIHPDPERRPSAMEL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELNAEKFKNSLLQKELKKAQMAAKVAAEERALFTDRMATRS-------TTQSNRTSRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [646]
'gi|5579439|gb|AAC46913.2| Wee1 kinase [Drosophila melanogaster]'                                    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFRQSEHEMSVTS---LDSSVELRSRSPSPQVFNPRNV--------------------------------------------------------------RFADD-DFDKDTPEGASPQHPLQQR----------------PKLSSGEEQQLGSKIGKEGGDGDVSMSPPC-QKVRALRLFSTP---------ATPK-------------------------------------------------------------------------T---------------------------------------------------ILQKST-TQCSNHLSAAAAAVN-ASRRSDDLFRL----------SERPRS---------------------------------------------------------------------------------------------------------------------------------------------LPLHNRK--------------------LPTQDTAN--VNPFTPDSLM-AHN----------------------------------------------------------------------------KKRCRTQFGRENLNLNVNAMQKYLLSDACDD-DVTEEAG------------DSMREIHQQA-PK--RLALHDTNI-SRFKREFMQVNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVRGSSFE------------------------------KRALNEVWAHAVLG-------------------------------------------KHDNVVRYYSAWAE----DDHMLIQNEFCDGGSLH---ARIQD-----HCLGE--AELKIVLMH---------------------VIEGLRYIHSNDLVHMDLKPENIFS----------------TMNPNAHKLVEVQPQ---QTKDDDGM-----DSVYEE------LR-HSENLVTYKIGDLGHVTSVKEP---------------------YVEEGDCRYLPKEILH--ED-Y---SNLFKADIFSLGITLFEAAGGGPLPKNGPEWHNLRDG-KVPILPS-------LSRD-------FNELIAQMMHPYPDKRPTSQSI--------FSHPILSAV-DSKSK--------------------------------------------------------------------------------------------------------------------------------------------------------------------LQLGLELTVEKRKNEILMNKLREAKKQIKLLEQRVNLLAVTKNPDS--LDGQRCLRSFTRRMRTPFSSHGKFDSISDRNKNVITNI------------------------------------------------------------------------------------------------------------------------------------------   [609]
'gi|82524304|ref|NP 001032299.1| hypothetical protein LOC327471 [Danio rerio] >gi|79158636|gb|AAI08039.1| Hypothetical protein L'    ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASVNATQQHLSFSSSWEE---DSSDNSFDEWTHKS----------------------------------------------------------------------------------------------------VPLRSPCRTPRIQRHR-----------------------NRSITVSP-------SVPTSPIPYAAWKKLRLCDSP---------STPK-------------------------------------------------------------------------S---------------------------------------------------LLSKST-MPCSSSKPC----------RSQRFLRL----------STA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------FERVPSVN--INPFTPDTVR-RNS----------------------------------------------------------------------------EHYKR--------KSQRSDDDEDYGPRSK-------EIQNS----------SEDESFF-LP-SK--RPAV-SARMLSRYESEFLELACIGVGEFGSVYRCVKRLDGCMYAIKRSRRPIAGSANE------------------------------QLALKEVYAHAVLG-------------------------------------------HHPHVVRYYSAWAE----DDHMIIQNEYCDGGSLH---DAITEKREQGEFFSV--PELRDLLLQ---------------------VSMGLKYIHNSGLVHLDIKPSNIFI----------------CRRS--------TLS-------AGGE-----GDSEEE------DE-SHSSGVVYKIGDLGHVTSISSP---------------------QVEEGDSRFLAYEVLR--ED-Y---THLPKADIFALGLTVLLAAGASPLPQNGDDWHRLRQG-ELPSLPH------ELPAL-------FKDLLKSLLDPDPTARPSATAL--------CRHDVLRKERAGKLA--------------------------------------------------------------------------------------------------------------------------------------------------------------------TQLRKELNVEKFRTAMLERELKEARL-AATSPQQSCQPG---------------SLPKAKRKLVGRNV-ARSVSFGFPGY------------------------------------------------------------------------------------------------------------------------------------------------   [527]
'gi|17136988|ref|NP 477035.1| wee CG4488-PA [Drosophila melanogaster] >gi|21430248|gb|AAM50802.1| LD27552p [Drosophila melanogas'    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFRQSEHEMSVTS---LDSSVELRSRSPSPQVFNPRKL--------------------------------------------------------------RFADD-DFDKDTPEGASPQHPLQQR----------------PKLSSGEEQQLDSKIGKEGGDGDVSMSPPC-QKVRALRLFSTP---------ATPK-------------------------------------------------------------------------T---------------------------------------------------ILQKST-TQCSNHLSAAAAAVN-ASRRSDDLFRL----------SERPRS---------------------------------------------------------------------------------------------------------------------------------------------LPLHNRK--------------------LPTQDTAN--VNPFTPDSLM-AHN----------------------------------------------------------------------------KKRCRTQFGRENLNLNVNAMQKYLLSDACDD-DVTEEAG------------DSMREIHQQA-PK--RLALHDTNI-SRFKREFMQVNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSSFE------------------------------KRALNEVWAHAVLG-------------------------------------------KHDNVVRYYSAWAE----DDHMLIQNEFCDGGSLH---ARIQD-----HCLGE--AELKIVLMH---------------------VIEGLRYIHSNDLVHMDLKPENIFS----------------TMNPNAHKLVEVQPQ---QTKDDDGM-----DSVYEE------LR-HSENLVTYKIGDLGHVTSVKEP---------------------YVEEGDCRYLPKEILH--ED-Y---SNLFKADIFSLGITLFEAAGGGPLPKNGPEWHNLRDG-KVPILPS-------LSRD-------FNELIAQMMHPYPDKRPTSQSI--------FSHPILSAV-DSKSK--------------------------------------------------------------------------------------------------------------------------------------------------------------------LQLGLELTVEKRKNEILMNKLREAKKQIKLLEQRVNLLAVTNNPDS--LDGQRCLRSFTRRMRTPFSSHGKFDSISDRNKNVITNI------------------------------------------------------------------------------------------------------------------------------------------   [609]
'gi|55250141|gb|AAH85597.1| Si:ch211-238n5.5 protein [Danio rerio]'                                    -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CSSSKPC----------RSQRFLRL----------STA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------FERVPSVN--INPFTPDTVR-RNS----------------------------------------------------------------------------EHYKR--------KSQRSDDDEDYGPRSK-------EIQNS----------SEDESFF-LP-SK--RPAV-SARMLSRYESEFLELACIGVGEFGSVYRCVKRLDGCMYAIKRSRRPIAGSANE------------------------------QLALKEVYAHAVLG-------------------------------------------HHPHVVRYYSAWAE----DDHMIIQNEYCDGGSLH---DAITEKREQGEFFSV--PELRDLLLQ---------------------VSMGLKYIHNSGLVHLDIKPSNIFI----------------CRRS--------TLS-------AGGE-----GDSEEE------DE-SHSSGVVYKIGDLGHVTSISSP---------------------QVEEGDSRFLAYEVLR--ED-Y---THLPKADIFALGLTVLLAAGASPLPQNGDDWHRLRQG-ELPSLPH------ELPAL-------FKDLLKSLLDPDPTARPSATAL--------CRHDVLRKERAGKLA--------------------------------------------------------------------------------------------------------------------------------------------------------------------TQLRKELNVEKFRTAMLERELKEARL-AATSPQQSCQPG---------------SLPKAKRKLVGRNV-ARSVSFGFPGY------------------------------------------------------------------------------------------------------------------------------------------------   [436]
'gi|68389748|ref|XP 683255.1| PREDICTED: similar to wee1a isoform 1 [Danio rerio] >gi|68389463|ref|XP 685180.1| PREDICTED: simil'    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFGAGRHGKSPNLKPVRQKLQFS-------------TSDGEEDSIEDANNSTGAESGFTELDSPVPLRRSLEKRPEDLGNSSPLSRNRD------------------------DDESW----DEEGFGSPS-----RVKPA-FYMKSSPSPRKSPPAYDSS-------------PERSYIHDDMEGSSSPIP-------DCPDTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSRAR-TMGSTS-------------RRVALFTN----------VDSTSKACLDGK------------------------------------------------------------------------------------------------------------------------------------------------------------------RNQTPRVN--INPFTPDSILVQSS----------------------------------------------------------------------------TLQRN--------NRKRSHWNDSCGEDM--------DASDA----------EIEDELI-PP-SK--RITMMENNMMSRYASEFHELEKIGSGQFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHPHVVRYYSAWAE----DDHMLIQNEYCNGGTLS---DVIAENNRRMHFLSE--LELKDLLLQ---------------------VSRGLKYIHSTALVHMDIKPSNIFI----------------SRKP--------AASV---------------EEFEDE------ED-GPTTNVVYKIGDLGHVTTVTNP---------------------QVEEGDSRFLANEVLQ--ED-Y---SNLKKADIFALALTVVSASGAEPLPTNGDKWHKIRQG-ILPHIPQ------VLSQE-------FLSLLKLMIHPDPTRRPSTSEL--------VRHPVLLTA-SRMSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------DQLRVELNAEKFKNALLQKELKKAQM-AKAAAEERVLTTDRVLTRS------TIQSSSRASRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [612]
'gi|68389750|ref|XP 706926.1| PREDICTED: similar to wee1a isoform 2 [Danio rerio] >gi|68389467|ref|XP 707804.1| PREDICTED: simil'    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSTS-------------RRVALFTN----------VDSTSKACLDGK------------------------------------------------------------------------------------------------------------------------------------------------------------------RNQTPRVN--INPFTPDSILVQSS----------------------------------------------------------------------------TLQRN--------NRKRSHWNDSCGEDM--------DASDA----------EIEDELI-PP-SK--RITMMENNMMSRYASEFHELEKIGSGQFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHPHVVRYYSAWAE----DDHMLIQNEYCNGGTLS---DVIAENNRRMHFLSE--LELKDLLLQ---------------------VSRGLKYIHSTALVHMDIKPSNIFI----------------SRKP--------AASV---------------EEFEDE------ED-GPTTNVVYKIGDLGHVTTVTNP---------------------QVEEGDSRFLANEVLQ--ED-Y---SNLKKADIFALALTVVSASGAEPLPTNGDKWHKIRQG-ILPHIPQ------VLSQE-------FLSLLKLMIHPDPTRRPSTSEL--------VRHPVLLTA-SRMSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------DQLRVELNAEKFKNALLQKELKKAQM-AKAAAEERVLTTDRVLTRS------TIQSSSRASRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [447]
'gi|51950018|gb|AAH82404.1| Wee1B protein [Xenopus laevis]'                                    ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNVQPRNMNVQPVRHKLFFS-----------------DTDEEEEDGHSTGEDSAFQESDSPVSRQREKQEGKPP-------------------------------------GGSWEELEEEEGFG-SSPI---KSPGD-FFMSDSPSYRQLAPASPTR---------------------SPQGPTSPIP-------ECPGTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSKAR-GIGSSALRF----------RGGTLFRE----------AEKAPKPEF---------------------------------------------------------------------------------------------------------------------------------------------------------------------VYSTPQVN--INPFTPDSLEIQSS----------------------------------------------------------------------------AGLCR--------GRKRALLNDSCGEDM--------EGSDC----------ELEDEDI-RP-AK--RIPITESNMKSRYATEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHPHVVRYYSAWAE----DDHMLIQNEYCNGGSLS---DVISENYRTMQYFTE--PELKDLLLQ---------------------VARGLKYIYSMSLVHMDIKPSNIFI----------------SRTT--------LPNTA--------------VEEADD------EE-CGSGKVIYKIGDLGHVTRVSSP---------------------QVEEGDSRFLANEVLQ--EN-Y---THLAKADIFALALTVWSAAGAEPFPTNGDQWHEIRQG-KLPRVPQ------LLSQE-------FVDLIKLMISPDPEKRPSSVAL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELDAEKFKNALLQKELKKAQI-AKAAAEERAHFPDRIATRS-------TTQNNRTTRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [588]
'gi|37046657|gb|AAH58071.1| Wee1 protein [Danio rerio]'                                    -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVQSS----------------------------------------------------------------------------TLQRN--------NRKRSHWNDSCGEDM--------DASDA----------EIEDELI-PP-SK--RITMMENNMMSRYASEFHELEKIGSGQFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHPHVVRYYSAWAE----DDHMLIQNEYCNGGTLS---DVIAENNRRMHFLSE--LELKDLLLQ---------------------VSRGLKYIHSTALVHMDIKPSNIFI----------------SRKP--------AASV---------------EEFEDE------ED-GPTTNVVYKIGDLGHVTTVTNP---------------------QVEEGDSRFLANEVLQ--ED-Y---SNLKKADIFALALTVVSASGAEPLPTNGDKWHKIRQG-ILPHIPQ------VLSQE-------FLSLLKLMIHPDPTRRPSTSEL--------VRHPVLLTA-SRMSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------DQLRVELNAEKFKNALLQKELKKAQM-AKAAAEERVLTTDRVLTRS------TIQSSSRASRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [405]
'gi|68390361|ref|XP 709003.1| PREDICTED: similar to Si:ch211-238n5.5 protein isoform 3 [Danio rerio]'                                ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKWSEMASVNATQQHLNFSSSWEE---DSSDNSFDEWTHKS----------------------------------------------------------------------------------------------------VPLRSPCRTPRIQRHR-----------------------NRSITVSP-------SVPTSPIPYAAWKKLRLCDSP---------STPK-------------------------------------------------------------------------S---------------------------------------------------LLSKST-MPCSSSKTC----------RSQRFLRL----------STA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------FERVPSVN--INPFTPDTVR-RNS----------------------------------------------------------------------------EHYKR--------KSQRSDDDEDYGPRSK-------EIQNS----------SEDESFF-LP-SK--RPAV-SARMLSRYESEFLELACIGVGEFGSVYRCVKRLDGCMYAIKRSRRPIAGSANE------------------------------QLALKEVYAHAVLG-------------------------------------------HHPHVVRYYSAWAE----DDHMIIQNEYCDGGSLH---DAITEKREQGEFFSV--PELRDLLLQ---------------------VSMGLKYIHNSGLVHLDIKPSNIFI----------------CRRS--------TLS-------AGGE-----GDSEEE------DE-SHSSGVVYKIGDLGHVTSISSP---------------------QVEEGDSRFLAYEVLR--ED-Y---THLPKADIFALGLTVLLAAGASPLPQNGDDWHRLRQG-ELPNLPH------ELPAL-------FKDLLKSLLDPDPTARPSATAL--------CRHDVLCKERAGKLA--------------------------------------------------------------------------------------------------------------------------------------------------------------------TQLRKELNVEKFRTAMLERELKEARL-AATSPQQSCQPG---------------SLPKAKRKLVGRNV-ARSVSFGFPGY------------------------------------------------------------------------------------------------------------------------------------------------   [532]
'gi|68390365|ref|XP 709005.1| PREDICTED: similar to Si:ch211-238n5.5 protein isoform 5 [Danio rerio] >gi|68390358|ref|XP 709002.'    ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASVNATQQHLNFSSSWEE---DSSDNSFDEWTHKS----------------------------------------------------------------------------------------------------VPLRSPCRTPRIQRHR-----------------------NRSITVSP-------SVPTSPIPYAAWKKLRLCDSP---------STPK-------------------------------------------------------------------------S---------------------------------------------------LLSKST-MPCSSSKTC----------RSQRFLRL----------STA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------FERVPSVN--INPFTPDTVR-RNS----------------------------------------------------------------------------EHYKR--------KSQRSDDDEDYGPRSK-------EIQNS----------SEDESFF-LP-SK--RPAV-SARMLSRYESEFLELACIGVGEFGSVYRCVKRLDGCMYAIKRSRRPIAGSANE------------------------------QLALKEVYAHAVLG-------------------------------------------HHPHVVRYYSAWAE----DDHMIIQNEYCDGGSLH---DAITEKREQGEFFSV--PELRDLLLQ---------------------VSMGLKYIHNSGLVHLDIKPSNIFI----------------CRRS--------TLS-------AGGE-----GDSEEE------DE-SHSSGVVYKIGDLGHVTSISSP---------------------QVEEGDSRFLAYEVLR--ED-Y---THLPKADIFALGLTVLLAAGASPLPQNGDDWHRLRQG-ELPNLPH------ELPAL-------FKDLLKSLLDPDPTARPSATAL--------CRHDVLCKERAGKLA--------------------------------------------------------------------------------------------------------------------------------------------------------------------TQLRKELNVEKFRTAMLERELKEARL-AATSPQQSCQPG---------------SLPKAKRKLVGRNV-ARSVSFGFPGY------------------------------------------------------------------------------------------------------------------------------------------------   [527]
'gi|30354631|gb|AAH51831.1| Wee1 tyrosine kinase [Homo sapiens]'                                    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFLSRQQPPPP-RRAGAACTLRQKLIFS--------PCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPE-RRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSW----EEEGFGSSSPV---KSPAAPYFLGSSFSPVRCGGPGDAS-------------PRGCGARRAGEGRRSPRP-------DHPGTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSKAR-GIDSSSVKL----------RGSSLFMD----------TEKSGKREFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------VRQTPQVN--INPFTPDSLLLHSS-----------------------------------------------------------------------------GQCR--------RRKRTYWNDSCGEDM--------EASDY----------ELEDET--RP-AK--RITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHSHVVRYFSAWAE----DDHMLIQNEYRNGGSLA---DAISENYRIMSYFKE--AELKDLLLQ---------------------VGRGLRYIHSMSLVHMDIKPSNIFI----------------SRTS--------IPNAA--------------SEEGDE------DD-WASNKVMFKIGDLGHVTRISSP---------------------QVEEGDSRFLANEVLQ--EN-Y---THLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQG-RLPRIPQ------VLSQE-------FTELLKVMIHPDPERRPSAMAL--------VKHSVLLSA-SRKSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------EQLRIELNAEKFKNSLLQKELKKAQM-AKAAAEERALFTDRMATRS-------TTQSNRTSRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [646]
'gi|4160308|emb|CAA12274.1| wee1-like kinase [Platynereis dumerilii]'                                    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSICKGRLIFHPRSERRRQDSGIAQTLNFQDD------DDNEMDSSFNDASMESVSPVRSKTSPSAFWD--------------------------------------------------------------------------SSLES-PVSSNTRKSRRSPRSARSQLLSPIPFSCEDSEEEHVAESLSAKSVHGKLP-------SFPLTPPH-KKLRSLRLYDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLQKAQ-RRITRAQRS----------MTDEKFCLNNNSLNGITTANGNTS----------------------------------------------------------------------------------------------------------------------------------------------ANGTCA--------------------SAERPLTN--INPFTPDNNN-LNL----------------------------------------------------------------------------SGGVK--------RPRHNGFDGSLTDDLI----------------------EEDLEDDMPS-TK--KIALREINT-FRYNEEFHQVSKLGDGEFGSVYKCIHRLDGCCYAIKKSKKPVAGSAYE------------------------------RQAMNEVYAHAVLG-------------------------------------------KHPHVVRYYSAWAE----NDHMYIQNEFCNGGSLA---DLCADNEKEDTLMTE--AELKQLLLQ---------------------VSQGLRYVHSQNLVHLDIKLGNIFI----------------DNSP--------QIQ-----SPESGF-----EDCEGE------ETEEMDYMVTYKIGDLGHVTSVSNP---------------------TVEEGDCRYLPNEILQ--EN-Y---DNLPKADIFSLALTLIEAGGGGPLPKNGEEWHKIRRG-ELPYLSN-------CSPA-------FNELLRSMAHPDPRARPSAAVL--------HQHPALCPF-ARKTR--------------------------------------------------------------------------------------------------------------------------------------------------------------------AQLRKELNEERFKNEVLTRQLQEAKRLSGASQPSPVQPSIIAAAKV--FPAPMMTQSTRQARLIGRKV-NRSISLNF---------------------------------------------------------------------------------------------------------------------------------------------------   [614]
'gi|49619025|gb|AAT68097.1| wee1a [Danio rerio] >gi|54144467|ref|NP 001005770.1| WEE1 homolog [Danio rerio]'                         -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFGAGRHGKSPNLKPVRQKLQFS-------------TSDGEEDSIEDANNSTGAESGFTELDSPVPLRRSLEKRPEDLGNSSPLSRNRD------------------------DDESW----DEEGFGSPS-----RVKPA-FYMKSSPSPRKSPPAYDSS-------------PERSYIHDDMEGCSSPIP-------DCPDTPPH-KTFRKLRLFDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSRAR-TMGSTS-------------RRVALFTN----------VDSTSKACLDGK------------------------------------------------------------------------------------------------------------------------------------------------------------------RNQTPRVN--INPFTPDSILVQSS----------------------------------------------------------------------------TLQRN--------NRKRSHWNDSCGEDM--------DASDA----------EIEDELI-PP-SK--RITMMENNMMSRYASEFHELEKNGSGQFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDE------------------------------QNALREVYAHAVLG-------------------------------------------QHPHVVRYYSAWAE----DDHMLIQNEYCNGGTLS---DVIAENNRRMHFLSE--LELKDLLLQ---------------------VSRGLKYIHSTALVHMDIKPSNIFI----------------SRKP--------AASV---------------EEFEDE------ED-GPTTNVVYKIGDLGHVTTVTNP---------------------QVEEGDSRFLANEVLQ--ED-Y---SNLKKADIFALALTVVSASGAEPLPTNGDKWHKIRQG-ILPHIPQ------VLSQE-------FLSLLKLMIHPDPTRRPSTSEL--------VRHPVLLTA-SRMSA--------------------------------------------------------------------------------------------------------------------------------------------------------------------DQLRVELNAEKFKNALLQKELKKAQM-AKAAAEERVLTTDRVLTRS------TIQSSSRASRLIGKKM-NRSVSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [612]
'gi|16549095|dbj|BAB70752.1| Wee1 [Carassius auratus] >gi|18413680|dbj|BAB84315.1| tyrosine kinase Wee1 [Carassius auratus langs'    ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASVNAAQQHLNFSSSGEE---DSSDNSF-EWAHRS----------------------------------------------------------------------------------------------------VPVRSPCRTPRVQRHR-----------------------TRSITVSP-------SNPTSPIPYAAWKKLRLCDSP---------STPK-------------------------------------------------------------------------S---------------------------------------------------LLSKAT-LPCSSSKPR----------RSQRFLRL----------STA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------FDRMPSVN--INPFTPETVR-RNS----------------------------------------------------------------------------EHHKR--------KSQRSDDDDDDAQRSK-------ETQNS----------SEDENFF-LP-SK--RPAV-SARMLSRYESEFLELSCIGVGEFGTVYRCVKRLDGCMYAIKRSRRPIAGSANE------------------------------QLALKEVYAHAVLG-------------------------------------------HHPHVVRYYSAWAE----DDHMIIQNEYCDGGSLH---DAITEKGEQGEFFCV--PEMSDLLLQ---------------------VSMGLKYIHSLGLVHLDIKPSNIFI----------------RRRP--------SSS-------AGGE-----GDSEEE------DE-SPSYGVVYKIGDLGHVTSISNP---------------------RVEEGDSRFLAFEVLR--ED-Y---THLPKADIFALGLTVLLAAGAPPLPQNGDDWHSLRQG-ALPSLPQ------ELPAP-------FKDLLKTLLDPDPTTRPSASAL--------CRHDVLRKERIGKLA--------------------------------------------------------------------------------------------------------------------------------------------------------------------AQLRKELNVEKFRTAMLERELKEARL-AATSPQQSSQLG---------------SLPKAGRKLVGRSA-ARSMSFGFPGY------------------------------------------------------------------------------------------------------------------------------------------------   [526]
'gi|54644087|gb|EAL32829.1| GA18218-PA [Drosophila pseudoobscura]'                                    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFRQSEHEMSVTSLEHLDSSVELRSGTPSPQVFNPRKL--------------------------------------------------------------RFADD-DFDKDQPESLSPQH-------------------------------------KKKVAADVSMSPPC-QKVRALRLFSTP---------ATPK-------------------------------------------------------------------------T---------------------------------------------------ILQKS---QCSNHLSAAAAVVN-ASRR-EELFRL----------SERPRC---------------------------------------------------------------------------------------------------------------------------------------------LPLHNRS--------------------MQPQDTAN--VNPFTPDSLL-AHN----------------------------------------------------------------------------KKRCRTQVGRE--NLNVNAIQKYLLSDTCDD-EGPEDVG------------DPMREIH-QA-PK--RLALHDTNI-SRFKREFMQVRVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSSFE------------------------------KRALNEVWAHAVLG-------------------------------------------KHDNVVRYYSAWAE----DDHMLIQNEFCDGGSLH---ARIQD-----HFLGE--AELKIVLMH---------------------VIEGLRYIHSNDLVHMDLKPENIFS----------------TMNPTAHKLVEAQPQ---QTKDDDGM-----DSVYEE------LRHTDIGDRIYKIGDLGHVTSVKEP---------------------HVEEGDCRYLPKELLK--DD-Y---SDLVRADIFSLGITLFEVAGGGPLPKNGPDWHKLRNG-EVPYLST-------LSKD-------FNELIALMMHPDPDQRPTSQSI--------FSHPILSAV-DSKSK--------------------------------------------------------------------------------------------------------------------------------------------------------------------LQLGLELTMERRKNEILMNKLRDAKKTIKQLEAKVNLFAVTNNPES--VEGQRCLRSFTRRTRTPFNTHGRY-SLGDRNKNVITNV------------------------------------------------------------------------------------------------------------------------------------------   [585]
'gi|47551231|ref|NP 999796.1| WEE1-like CDK tyrosine kinase [Strongylocentrotus purpuratus] >gi|1171350|gb|AAA86277.1| WEE1-like'    ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRLPNALILAMLLVQKAKVTRVFAAYSDFNEIQEGAI-DHSPISSSFSDDRDDSLNLTAEWDPALQLPKAVHQDGVYNVDPNSRLHDGEN-----------------------------------------------------SIASP-HFRRPSDSSCSPSPMVCAS-----------------------------SPASSAGGGDAVGSPPPHKRLRNLKLFDSP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LIQKAN--ASARRNKL----------LASRLFSE----------KPASSTPTDHGDGPIAFGIARPHTAPN------------------------------------------------------------------------------------------------------------------MRNLQRRSTRIPK--------------------TRQQNVAN--VNPFTPSAML-QNA----------------------------------------------------------------------------TKKRL--------RQERSILDDDE------------DLDDD----------MDGSYTE-NP-AK--RIALRDSDI-SRYEAEFVEVGKVGSGEFGSVYKCINRLDGCFYAIKKSKRPIAGSAFE------------------------------QMALNEVYAHAVLG-------------------------------------------THIHVVRYYSAWSE----AGHMIIQNEYCNGGSLA---DIISSNKQNNHRMTE--IELKQVLVQ---------------------IAQGLKYIHSEGLVHMDIKPGNIFI----------------SKKE--------PLP---STTPESEKIDEEEEEGATE------DN-TPLASLIYKIGDLGHVTSISNP---------------------KVEEGDVRFLPVEILQ--EE-H---THLTKADIFALALTAYLAAGGESLPKNGDDWHRIRQG-HFPPLPH-------ISTD-------LVDLLQTMIDPDPSQRPSASAL--------VQHPLLCPN-SKRSF--------------------------------------------------------------------------------------------------------------------------------------------------------------------TQLKRELNVAKFQNAILSRELNEARKSTMNPPPKSR---------------------SNAGRLIGKKV-NRSMSLTIY--------------------------------------------------------------------------------------------------------------------------------------------------   [624]
'gi|66560584|ref|XP 624069.1| PREDICTED: similar to Wee1-like CDK Tyrosine kinase [Apis mellifera]'                                  -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVAQKLHFDACDI----QDEELNISCRTNSSGCDVDDILDSSAEDLGCSPPLQPRKLSFSNTMDC-------------------------------------------SDSENNQSVPINNNKTPIS-NMTGTSRIRIPPRENICSQKI------------------------------------SMACSPPY-KRVRALRLFDSP---------ATPK-------------------------------------------------------------------------T---------------------------------------------------LMEKSAMHTPFPS-------------KCTRLFSL----------DKSRSCNYQN--------------------------------------------------------------------------------------------------------------------------------------------------------------------KSDKPTAN--VNPFTPNGML-LTA----------------------------------------------------------------------------RKRTR--------SKRSLNGSPDIQIPKF-------DLADSE---------DSDNEIE-QA-TK--RVALQDSNI-LRYHQEFHELGLIGTGEFGSVYKCINRLDGCTYAIKKSIKPVAGSINE------------------------------KNALNEVYAHAVLG-------------------------------------------KHQHVVRYYSAWAE----DNHMIIQNEYCNGGSLA---DAIINLEKEKKHFTE--AEMRQLLLH---------------------VAEGLRYIHSMQLVHMDIKPGNIFI----------------SKEK--------RLL---AVNYDSA------DDGFDE------EE-TIEEEITYKIGDLGHVTSVNNP---------------------QVEEGDCRYLPTEILR--ED-F---SHLPKADIFAFGLTVYEAGGGGPLPKNGPEWHDIRNG-NLKELSH-------YSRD-------LNELLKLMIHPNPEMRPSAICL--------IQHRVLCPF-GNKTK--------------------------------------------------------------------------------------------------------------------------------------------------------------------AQLRRELNAEKLKNEILSKQLQEAAKCLKTIAPNVAAINNTMNAGG---YKLRPTPTRTSSRAVGKKV-NRSNSTTNF--------------------------------------------------------------------------------------------------------------------------------------------------   [589]
'gi|55237920|gb|EAA12306.2| ENSANGP00000010303 [Anopheles gambiae str. PEST] >gi|58390418|ref|XP 317709.2| ENSANGP00000010303 [A'    ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLSPPY-RKVQALRLFDTP---------ATPK-------------------------------------------------------------------------T---------------------------------------------------ILQKSTNTMFRRQVASGSAGTTNG--RRVADFH-----------TDKPKP---------------------------------------------------------------------------------------------------------------------------------------------VPLHRRY--------------------DVGLPPAN--VNPFTPPAMF-MRT----------------------------------------------------------------------------KKRTR---QEGPESAKATLGHGGIGTGTANTIRSVQHGG------------GRVRRFR-QA-PK--RLALQDSNI-SRYEKEFIQLSLLGTGEFGQVYQCLNRLDGCIYAIKKSIRPVAGSSFE------------------------------KTALNEVYAHAVLG-------------------------------------------KHDNVVRYYSAWAE----NNHMLIQNEYCNGGSLQ---TVLQE-----RCLKE--SELRTLLLH---------------------IAEGLKYIHSNDLVHMDLKAGNIFL----------------SKTP--------LRS---GTPLHGAASTAVPLDCPDDGFEDVYDDLENEFLVTYKIGDLGHVTSINDP---------------------QVEEGDCRYLPNEILQ--ED-Y---SNLAKGDIFSLGITLYEAAGGGPLPKNGTGWHQLRGG-QFPDLPN-------IGKD-------FNDLIKQMMHPNPEKRPSSTTI--------FNHPVLSPI-DSKTK--------------------------------------------------------------------------------------------------------------------------------------------------------------------AQLCLELSMERQKNEVLMRKLKEQAKLLKSIEQQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [475]
'gi|73978828|ref|XP 532748.2| PREDICTED: similar to Wee1-like protein kinase (WEE1hu) [Canis familiaris]'                            ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDSSINKELKQKLNVSYCEE----ESESEGQKEAPESRETQSQTPDWAEG-QESEAKFTPPR-------------------------------------------------------------TPS---SSIHG-VGTFEEKDKMSPDQALR--------------------------TPGPGFH-------KCPGTPAQPDSRSEVVHCESP---------YTPK-------------------------------------------------------------------------S---------------------------------------------------LLSQSV-ISSTEKLPS----------RGSKHLRF----------TPVPFV----------------------------------------------------------------------------------------------------------------------------------------------D----E--------------------MTSSALVN--INPFTPESY--RKQ----------------------------------------------------------------------------FLRSN--------GKRKTRGDLE-------------EADPG----------EGKVEQG-LP-AK--RCVLRETNMASRYEKEFLEVEKIGVGEFGTVYKCIKRLDGCVYAIKRSMKPVAGLSNE------------------------------NLALHEVYAHAVLG-------------------------------------------HHPHVVRYYSAWAE----DDHMIIQNEYCNGGSLQ---TAISENTKSGNHFPE--LKLKDILLQ---------------------ISLGLKYIHNSGMVHLDIKPSNIFI----------------CHKM--------QCD---S---PVVP-----EEIENE------ADWFLSANVMYKIGDLGHVTSISKP---------------------KVEEGDSRFLANEILQ--ED-Y---QHLPKADIFALGLTIAVAAGAESLPANGAKWHHIREG-NLPDIPQ------KLSEE-------FHNLLKNMIHPDPSERPSAAGL--------ARSRVLRPS-LRKAE---------------------------------------------------------------------------------------------------------------------------------------------------------------------ELQQQLNLEKSKTATLER-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [515]
'gi|76633630|ref|XP 598279.2| PREDICTED: similar to Wee1-like protein kinase (WEE1hu) [Bos taurus]'                                  ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDHNENKELKQKLNFSCCEE----EHENKGQEEAQESEEAQTQTPERPRG-QDSEVKLTPPR-------------------------------------------------------------TPL---GNEYD-LSALYERDQASPDQGLR--------------------------TPVSHSL-------ARPETPPAPPDKSGPSHCESP---------FTPK-------------------------------------------------------------------------KEVLTLSWSSDEQALIGEQRAERFLGPFCCLRIAATGILCALFQERVPYCFGQVSQSM-ISSTGKPLP----------RSSKHLKL----------TPGPFI----------------------------------------------------------------------------------------------------------------------------------------------D----E--------------------MTSLALVN--INPFTPESY--RKQ----------------------------------------------------------------------------FLKSN--------GKRKTRGDLE-------------ESSPG----------EGKGEQG-LP-AK--RCVLRETNMASRYEKEFLEVEKIGVGDFGTVYKCIKRLDGCVYAIKRSTKPLGGLSDE------------------------------TLAMHEVYAHAVLG-------------------------------------------QHPHVVRYYSAWAE----DDYMIIQNEYCNGGSLQ---AAVTENTKSGSHFPE--PRLKDILLQ---------------------ISLGLKYIHSSGMVHLDIKPSNIFI----------------CHKM--------QSD---S---PVVL-----EEAENE------ADWFFSADVMYKIGDLGHVTSISNP---------------------KVEEGDSRFLANEILQ--EN-Y---QHLPKADIFALGLTIAVAAGAELLPTNGTEWHHIREG-NLPDIPQ------ELSKE-------FHQLLESMIHPDPAERPSAAAL--------AKSRVLCPS-LGKTE---------------------------------------------------------------------------------------------------------------------------------------------------------------------ELQHQLNLEKFKTATLQR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [566]
'gi|51703884|gb|AAH81031.1| Xe-Wee1A protein [Xenopus laevis]'                                    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRTAMSCGGGLVQRLDFSSSDEE---DGLSNGINEGPQKGSPVSS--------------------------------------------------------------------------------------------WRTNNCPFPITPQRNEREL---------------SPTQELSPSSDYSPDPS---VGAECPGTPLHYSTWKKLKLCDTP---------YTPK-------------------------------------------------------------------------S---------------------------------------------------LLYKTL-PSPGSRVHC----------RGQRLLRF----------VAGTGAE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LDDPSLVN--INPFTPESY--RQT----------------------------------------------------------------------------HFQPN--------GKRKERPEDDCRTDR--------QMKYA----------EKEHPAV-FQ-SK--RFVLRETNMGSRYKTEFLEIEKIGAGEFGSVFKCIKRLDGCFYAIKRSKKPLAGSTDE------------------------------QLALREVYAHAVLG-------------------------------------------HHPHVVRYYSAWAE----DDHMIIQNEYCNGGSLQ---DLIVDNNKEGQFVLE--QELKEILLQ---------------------VSMGLKYIHGSGLVHMDIKPSNIFI----------------CRKQ--------TELGQ--------------EESDGE------DD-LSSGSVLYKIGDLGHVTSILNP---------------------QVEEGDSRFLANEILQ--ED-Y---SQLPKADIFALGLTIALAAGAAPLPCNEDSWHHIRKG-NLPHVPQ------LLTPI-------FLALLKLLVHPDPVMRPPAASL--------AKNSVLRRC-VGKAA---------------------------------------------------------------------------------------------------------------------------------------------------------------------QLQKQLNVEKFKTAMLERELKAAKL-AQTSGKDECSDLPPMSGFS----------CRGRKRLVGAKN-TRSLSFTCGGY------------------------------------------------------------------------------------------------------------------------------------------------   [555]
'gi|1351421|sp|P47817|WEE1A XENLA Wee1-like protein kinase >gi|644770|gb|AAC59664.1| Wee1A kinase'                                   -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRTAMSCGGGLVQRLDFSSSDEE---DGLSNGINEGPQKGSPVSS--------------------------------------------------------------------------------------------WRTNNCPFPITPQRNEREL---------------SPTQELSPSSDYSPDPS---VGAECPGTPLHYSTWKKLKLCDTP---------YTPK-------------------------------------------------------------------------S---------------------------------------------------LLYKTL-PSPGSRVHC----------RGQRLLRF----------VAGTGAE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LDDPSLVN--INPFTPESY--RQT----------------------------------------------------------------------------HFQPN--------GKRKERPEDDCRTDR--------QMKYA----------EKEHPAV-FQ-SK--RFVLRETNMGSRYKTEFLEIEKIGAGEFGSVFKCVKRLDGCFYAIKRSKKPLAGSTDE------------------------------QLALREVYAHAVLG-------------------------------------------HHPHVVRYYSAWAE----DDHMIIQNEYCNGGSLQ---DLIVDNNKEGQFVLE--QELKEILLQ---------------------VSMGLKYIHGSGLVHMDIKPSNIFI----------------CRKQ--------TELGQ--------------EESDGE------DD-LSSGSVLYKIGDLGHVTSILNP---------------------QVEEGDSRFLANEILQ--ED-Y---SQLPKADIFALGLTIALAAGAAPLPCNEDSWHHIRKG-NLPHVPQ------LLTPV-------FLALLKLLVHPDPVMRPPAASL--------AKNSVLRRC-VGKAA---------------------------------------------------------------------------------------------------------------------------------------------------------------------QLQKQLNVEKFKTAMLERELKAAKL-AQTSGKDECSDLPPMSGFS----------CRGRKRLVGAKN-TRSLSFTCGGY------------------------------------------------------------------------------------------------------------------------------------------------   [555]
'gi|2827996|gb|AAB99952.1| wee1 homolog [Xenopus laevis]'                                    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRMAMSCGGRLVQRLDFSSSEEE---DGLSNRINEAPQKGSPVSS--------------------------------------------------------------------------------------------WRTNNCPFPITPQRNERGL---------------SPTQELSPSSDYSPDPSDKGVGGECPGTPLHYSTWKKLKLCDTP---------YTPK-------------------------------------------------------------------------S---------------------------------------------------LLYKTL-PSPGSRVHC----------RGQRLLRF----------VAGTGAE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------TEDPTLVN--VNPFTPQSY--RQT----------------------------------------------------------------------------HFQPN--------GKRKERPEDDCSSDS--------QMKFT----------DKEHPAV-FQ-SK--RFVLRETNMESRYKTEFLEIEKIGAGEFGSVFKCVKRLDGCFYVIKRSKKPLAGSTDE------------------------------QLALREVYAHAVLG-------------------------------------------HHPHVVRYYSAWAE----DDHMIIQNEYCNGGSLQ---DLIMENNKKGQFVPE--QELKEILLQ---------------------VSMGLKYIHGSGLVHMDIKPSNIFI----------------CRKQ--------TEVGE--------------DESDGE------DD-VASASVLYKIGDLGHVTSILNP---------------------QVEEGDSRFLANEILQ--ED-Y---RQLPKADIFALGLTIALAAGAAPLPCNEDGWHHIRKG-NLPHIPQ------PLTPA-------FLALLKLLVHPDPATRPPATSL--------AKNSVLRRC-VGKAA---------------------------------------------------------------------------------------------------------------------------------------------------------------------ELQKQLNVEKFKTAMLERELQAAKL-AQ----DECLDLPPVSGFS----------CRGRKRLVGAKN-ARSLSFTCGGY------------------------------------------------------------------------------------------------------------------------------------------------   [554]
'gi|49899753|gb|AAH76799.1| Unknown (protein for MGC:83736) [Xenopus laevis]'                                    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRTAMSCGGGLVQRLDFSSSEEE---DGLSNGINEAPQKGSPVSS--------------------------------------------------------------------------------------------WRTNNCPFPITPQRNERGL---------------SPTQELSPSSDYSPDPSDKGAGGECPGTPLHYSTWKKLKLCDTP---------YTPK-------------------------------------------------------------------------S---------------------------------------------------LLYKTL-PSPGSRVHC----------RGQRLLRF----------VAGTGAE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------TEDPTLVN--VNPFTPQSY--RQT----------------------------------------------------------------------------HFQPN--------GKRKERPEDDCSSDS--------QMKFT----------DKEHPSV-FQ-SK--RFVLRETNMESRYKTEFLEIEKIGAGEFGSVFKCVKRLDGCFYVIKRSKKPLAGSTDE------------------------------QLALREVYAHAVLG-------------------------------------------HHPHVVRYYSAWAE----DDHMIIQNEYCNGGSLQ---DLIMENNKKGQFVPE--QELKEILLQ---------------------VSMGLKYIHGSGLVHMDIKPSNIFI----------------CRKQ--------TEVGE--------------DESDGE------DD-VSSASVLYKIGDLGHVTSILNP---------------------QVEEGDSRFLANEILQ--ED-Y---RQLPKADIFALGLTIALAAGAAPLPCNEDGWHHIRKG-NLPHIPQ------PLTPA-------FLALLKLLVHPDPATRPPAASL--------AKNSVLRRC-VGKAA---------------------------------------------------------------------------------------------------------------------------------------------------------------------ELQKQLNVEKFKTAMLERELQAAKL-AQ----DECLDLPPVSGFS----------CRGRKRLVGAKN-ARSLSFTCGGY------------------------------------------------------------------------------------------------------------------------------------------------   [554]
lcl|15022_Cre_unnamed_protein_product                                    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATAAMKPP-GGSIFNYYSKQKQQSQQSQQQQCSESTSSLQMSLRHMNLGDISRPPAANPPDGPVLSQEPRPHMRALRPRVLDLSSQPSQEQYTPDHLTPQ-------------------------------------------------------------------------------------------------------------------------------EQLFRMEYEPSTMQVDDDVSRSPAPSPRAMKRPRPLKVLPGNMDDEVSSQSQSQSRSVGEPSTCSKALS------------------------------------------------------------------------------------------------------------------GRPPIPKL-------------------------REVQPPMP--RNPYLVRADDDNHV------------------------------------------------------------------------------------------------------------------------------------------FQASQSCLNRGNY-SRFLWDYHQEAELGHGNFSKVYKAVHRLTGIAYAVKTNKVPITTLQAR------------------------------NMWLNEMQALAAVQ-------------------------------------------PHPNIVGLYDTWFEPGGDAEQAYIKQELCGE-------SLRDMFKRRV-QFKE--VEVLEILRQ---------------------MASALKRIHDLGMVHLDIKPDNIYL----------------AAPS-------------------PADLALRAASGANASSSAGSSSGGSSAAPVYKLGDFGLAMLPGGQRA-------------------GTSEGDVKYLAPEALK--SRDFLTSGLADRLDVFALGASVYELLRGTELPKNGQSYHDIRQG-KLF----L----PSASTR-------IINLLKKMMSPDPAQRPTADGI--------LRSTLLQAGTSSSQL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AATTSTPLPMSQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [523]
'gi|31127136|gb|AAH52883.1| Similar to Wee1-like protein kinase (WEE1hu) [Mus musculus] >gi|41235773|ref|NP 958758.1| hypothetic'    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADTETDQGLNKKLSFSFCEE----DTESEGQMTAQDIGGAQSQKPGREES-EELEGPVPPTR----------------------------------------------------------------------DE-LHTSLSRDKGSPGPDLW--------------------------KSVSGPP-------KCPETPVL-HSKSKPPVPTNF---------STPK-------------------------------------------------------------------------N---------------------------------------------------SLGQPE-ISLLEKLSS----------RSSRHMRL----------TPASLV----------------------------------------------------------------------------------------------------------------------------------------------D----E--------------------KTSLSLVN--INPFTPETY--RKL----------------------------------------------------------------------------LLQSK--------GKRKTRDYLE-------------ETGEE----------ESKSVQW-LP-AK--RSILQETNMASRYEKEFFEIEKIGVGEFGTVYKCIKRLDGCIYAIKRSAKSFSGLSNE-------------------------------LDLHEVYAHAVLG-------------------------------------------HHPHVVRYYSSWIE----DDHVVIQNEYCNGGSLQ---AAISENTASNNHFQE--PKLKDILLQ---------------------ISLGLKYIHNSGMVHLDIKPSNIFI----------------CHKM--------QCD---S---PVGP-----EEAESE------ADWFLNASVMYKIGDLGHATSISKP---------------------KVEEGDTRFLANEILQ--EN-Y---QHLPKADIFALGLTIAVAAGAESLPINGDMWHHIRKG-NFPEISQ------ELSDD-------FYGLLKNMIHPAPKERPSAAAL--------ARSRILWPF-LEKTD---------------------------------------------------------------------------------------------------------------------------------------------------------------------ELQKQLNLEKSKTATLKRELKKARH-IQTPQREVHHCYYQICKGS-------------RHLLVGGRR-KAPSSFTRGTSSV----------------------------------------------------------------------------------------------------------------------------------------------   [555]
'gi|51593306|gb|AAH80784.1| Similar to Wee1-like protein kinase (WEE1hu) [Mus musculus]'                                    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADTETDQGLNKKLSFSFCEK----DTESEGQMTAQDIGGAQSQKPGREES-EELEGPVPPTR----------------------------------------------------------------------DE-LHTSLSRDKESPGPDLW--------------------------KSVSGPP-------KCPETPVL-HSKSKLPVPTNF---------STPK-------------------------------------------------------------------------N---------------------------------------------------SLGQPE-ISRLEKLSS----------RSSRHMRL----------TPASLM----------------------------------------------------------------------------------------------------------------------------------------------D----E--------------------KTSLSLVN--INPFTPETY--RKL----------------------------------------------------------------------------LLQSK--------GKRKTRDYLE-------------ETGEE----------ESKSVQW-LP-AK--RSILQETNMASRYEKEFFEIEKIGVGEFGTVYKCIKRLDGCIYAIKRSAKSFSGLSNE-------------------------------LDLHEVYAHAVLG-------------------------------------------HHPHVVRYYSSWIE----DDHVVIQNEYCNGGSLQ---AAISENTASNNHFQE--PKLKDILLQ---------------------ISLGLKYIHNSGMVHLDIKPSNIFI----------------CHKM--------QCD---S---PVGP-----EEAESE------ADWFLNASVMYKIGDLGHATSISKP---------------------KVEEGDTRFLANEILQ--EN-Y---QHLPKADIFALGLTIAVAAGAESLPINGDMWHHIRKG-NFPEISQ------ELSDD-------FYGLLKNMIHPAPKERPSAAAL--------ARSRILWPF-LEKTD---------------------------------------------------------------------------------------------------------------------------------------------------------------------ELQKQLNLEKSKTATLKRELKKARH-IQTPQREVHHCYYQICKGS-------------RHLLVGGRR-KAPSSFTRGTSSV----------------------------------------------------------------------------------------------------------------------------------------------   [555]
'gi|74137789|dbj|BAE24069.1| unnamed protein product [Mus musculus] >gi|74228469|dbj|BAE25345.1| unnamed protein product [Mus mu'    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADTETDQGLNKKLSFSFCEE----DTESEGQMTAQDIGGAQSQKPGREES-EELEGPVPPTR----------------------------------------------------------------------DE-LHTSLSRDKESPGPDLW--------------------------KSVSGPP-------KCPETPVL-HSKSKLPVPTNF---------STPK-------------------------------------------------------------------------N---------------------------------------------------SLGQPE-ISLLEKLSS----------RSSRHMRL----------TPASLM----------------------------------------------------------------------------------------------------------------------------------------------D----E--------------------KTSLSLVN--INPFTPETY--RKL----------------------------------------------------------------------------LLQSK--------GKRKTRDYLE-------------ETGEE----------ESKSVQW-LP-AK--RSILQETNMASRYEKEFFEIEKIGVGEFGTVYKCIKRLDGCIYAIKRSAKSFSGLSNE-------------------------------LDLHEVYAHAVLG-------------------------------------------HHPHVVRYYSSWIE----DDHVVIQNEYCNGGSLQ---AAISENTASNNHFQE--PKLKDILLQ---------------------ISLGLKYIHNSGMVHLDIKPSNIFI----------------CHKM--------QCD---S---PVGP-----EEAESE------ADWFLNASVMYKIGDLGHATSISKP---------------------KVEEGDTRFLANEILQ--EN-Y---QHLPKADIFALGLTIAVAAGAESLPINGDMWHHIRKG-NFPEISQ------ELSDD-------FYGLLKNMIHPAPKERPSAAAL--------ARSRILWPF-LEKTD---------------------------------------------------------------------------------------------------------------------------------------------------------------------ELQKQLNLEKSKTATLKRELKKARH-IQTPQREVHHCYYQICKGS-------------RHLLVGGRR-KAPSSFTRGTSSV----------------------------------------------------------------------------------------------------------------------------------------------   [555]
'gi|62647164|ref|XP 578249.1| PREDICTED: similar to Wee1-like protein kinase (WEE1hu) [Rattus norvegicus]'                           ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPHLQVQDTDIRLYSVGCKADMQLAGEEVIYSVSHSETFSPACTEMADAETDQELNKKLNFSFCEE----DTENEGQMTAQDIGRAQSQKPRRDQS-EELEGPVSSPR----------------------------------------------------------------------DE-LYTSLNRDKQSPGPALR--------------------------TSVSDFS-------TCPDTPVL-NSKSKLPVPTNF---------STPK-------------------------------------------------------------------------N---------------------------------------------------LLGQPE-ISSLEKLYV----------RSSKHLRL----------TPTSLM----------------------------------------------------------------------------------------------------------------------------------------------D----E--------------------KTSLSLVN--INPFTPETY--RKL----------------------------------------------------------------------------FLQSK--------GKRKTRDYLK-------------ELFDKSVAEQAIDLTSSRQLNV-LE-TK--RSVLQETNMASRYEKEFFEVEKIGVGEFGTVYKCIKRLDGCIYAIKRSAKSFSGLSND-------------------------------LDLHEVYAHAVLG-------------------------------------------HHPHVVRYYSSWVE----DNHVVIQNEYCNGGSLQ---AAISENADSDNHFQE--PKLKDILLQ---------------------ISLGLKYIHNSGMVHLDIKPSNIFI----------------CHKI--------QSD---C---PVGP-----EETESE------ADWFLNANVMYKIGDLGHATSISKP---------------------KVEEGDTRFLANEILQ--EN-Y---QHLPKADIFALGLTIAMAAGAEPLPINGDKWHHIRKG-NFPEISQ------ELSDD-------FYGLLKNMIHPVPEERPSAATL--------ARSRILWPF-LEKTE---------------------------------------------------------------------------------------------------------------------------------------------------------------------ELQKQLNLEKSKTATLKRELKKAQH-IHTPQRDVHHCYQQTYKSS----------RSTRHLLVGGRR-KEPPSFTSGSISTAHIVDFLFFLAYRELCRLCAPEASRWQSGLARQVREERRLRQSCESVVHERVRAWGAGVRLLAGVSVSPLFPVQPAIATLEEKYPLIPAARLGSRAYSALTGTKAQI-----------------------------------   [720]
'gi|50729280|ref|XP 425491.1| PREDICTED: similar to Wee1A kinase [Gallus gallus]'                                    -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDWENNDFIQRLDFSSCGE----EGEDRSINEED----TLSSSPIKHCDFQKWNSPLPATPH------------------------------------------------------------------RKLSE-IFLSRTKSWVSPTLKSS--------------------------PGVSRTH-------GNAETPLH-ITWKKLQLCDTP---------HTPK-------------------------------------------------------------------------S---------------------------------------------------LLSKTAFPSPGAKVPP----------KGFRHLRF----------TPGADLDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------STQASLVN--INPFTPESY--RQM----------------------------------------------------------------------------LFLPN--------GKRKAREICSAGFDP-------------------------------LVEKRLLRCPLKDSNMVSRYQKEFLELERIGVGEFGSVYKCIKRLDGCVYAIKRSKRPLAGSSDERLVQWYLYWQLFDKLEVLLNIHFKALLQQLQLALREVYAHAVLG-------------------------------------------HHPHVVRYYSAWAE----DDHMIIQNEHCNGGSLQ---DVLLENAKRGQYFPE--AKLKEILLQ---------------------VSMGLKYIHNSGLVHLDIKPSNIFI----------------CHKL--------VVE---G---QAGQ-----EE-SDS------DD-EFSSGVMYKIGDLGHVTSIANP---------------------QVEEGDRRFLANEILQ--EQ-Y---FHLPKADIFALALTIALAAGAGPLPHNGAMWHHIRKG-NIPSIPQ------KLPNG-------FIELLKLMIHPDPMERPSATAL--------TKHPILRPS-LGKAV---------------------------------------------------------------------------------------------------------------------------------------------------------------------QLQKQLNVEKCKTAMLER-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [533]
gnl|CMER|CMT590C_CDK_tyrosine_kinase_WEE1                                    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRVGVRSKTQAQQGPPPTAVLKMRRASRLGTPRLPAALVTSSAAPGQQLDTDSIAEASVGRKRRLSRTEERPRLGALGSTTESAGPSRQRTIPEVLERKAGLVVSTPKLELPRLDLISWGTTPHGARRLTPEAADIETPVN-SAEFVATPFLGEGASRDAAMGLDAGIYRTPTFTIATAVNANWMNSQAASAADEDSNASSTLAPEQGAGASQPPPSPSP------------------------------------------------------------------------------------------------------------------------------------------ALKRLHLLNGSANGRWCPARESNFSAPRPPLQSQRHEYQTQAVATADMDAPESSTFSSQMHTQTSVLSQDTLGMLLARRRAVQAARTSTDVVGRITFSQAGDDEAVANGNSAPGGSLSELRPVTAGIPTLVRDHAMMITSQVPARSARRPTENPLWANTDARTQSQTEAGPGNGLAAERIHRSLWGSRRAPATATAAELRDSFLAMGDVIQCTENGRHREAQPTSAPIINPFLVCTDEPE---------------------------------------------------------------------------------------------------------------------------------TPSKAEMSSAQLRPNQLLPEVASSPSRFLQQFEEVQILGSGVKGQVLLARHRTDGCLYAVKRTTRPLLSRTDR------------------------------LDALREVHALAAVG-------------------------------------------AHENIVRYHTAWFEEH--DTRLYLQLEYCAGGSMQL--SGRTRLTTASKLPHY--LRLVRLLGH---------------------VAAALAHCHAHGIAHMDVKPENMLIGSVRKPHQQLQLRKQPTKQE------------------------------------------------VFKLADFGLACRLDGADF-------------------TGSEGDSRYLCQSVLS--EAPL---GSLVPVDVFALGISIYELLTEQPLPTKGDEWQALRAG-RLDRLDALTAAPGETSTDANLVLSFLIDWIRRCVQPSVQERPTAAEVALACETWLVEHASLSC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDP   [791]
'gi|89293014|gb|EAR91002.1| Protein kinase domain containing protein [Tetrahymena thermophila SB210]'                                -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEGYASPPSKRDTEKANKYLYSKEQYINSSN-TKKNNFISHFDNTAKPHLHGTNENSKTKKTQFNFESIVKPNYGITLTQTPNVQKNLPSYEKIPQQRLFTQQINKYNTK----NEFDHSTPKKQHNY--------------------------------------------------------------------------------------------------------------------------------------------------------------------KKSLFSSDSQESSTERENDNHYYSNQN------------------------------------------------------------------------------------------------------------------KENDSHSKNKKNNRNHIFAVSEVPAQKRQNQISQLQKSARK--VNPFTSNETLTNKNQVIVAPFDRENRQMNMTIHQRDNKKVSINAVNHLNNNKNANQILLPSPKEFKQLNSTHKIDHQSPHVNCFTNQIMNSANQKHQINRSNTSNSDSNNEQNNNSISSFSINSGRSCNYGNNNNSNNILNQTPSKNNNQNNSKASSQPFFEEEM-DRFEQDYEVLQVLGSGFFGTVYKCQNRIDKNIYAVKVTKEQIRGENSQ------------------------------KQILKEAQALASLSA----------------------------------------CDEVEYIVCYHSAWIE----DRQLHLAMEFCDS-------NLANFPLPQPPNYNQFYQMIKKIFQD---------------------VVKGLHYLHQQNLVHLDLKPENILYN---------------KKQN------------------------------------------------KFKIADLGLALIANKDNEKYN----------------QIEEGDARYLAKEILN-----YYEAVDLKKADIFSLGAMMYHLVTQEQLPTNGDEWLQIRQG-HLPNLDSL----NQCPKE-------LKQMIRQMMNPDPELRLSTQEI--------LDSSYMKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HLINEIKWQKILKNLLLISIQKLEKNQQTQQITRRKSLPILKKINFI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [674]
'gi|55978006|gb|AAV68603.1| protein kinase Wee1 [Ostreococcus tauri]'                                    ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDISTHRDAGARLMAPSP-------RRKVPL-----------------------------------------------------------------------------------------------------------------------------VAYNDVKDSPALKMSETPAKQRFETSPLSVLLK-----------PISPLSENSPDWSDERTREGDASAIGS------------------------------------------------------------------------------------------------------------------PEEPTTPRGDALG---VFAKEVDHAARWDVRAFPADAPASA---------NSVEVRRRRGKTRSGDFDRENTFDREFDFDDGRGVGDHDGDGHPMFRVFGRDIGKPPRASSEREEGDGLGKTSGRGRTRGLFGSFGNRSGAFERVGSGSSSMGSKRSDEIGQLSRM------------------NSLAETKVLTSTLLVRQTSVSGDAQFDFDDHFRFEQQIGASQNSEVWLVTSKVSGNAFVVKKCLHSFTTEAQR------------------------------AKYKREVEAAALLP-------------------------------------------EHPNIVRYYRSWQQ----DQHFYIQMEHCACGSLT---SVFARLPPQT-LVAE--LDVWRLAEQ---------------------TASGLAFMHLHRIIHLDVKPDNIYI----------------DVSG------------------------------------------------TCKIGDFGLAYVMESGW--------------------DWEEGDGGYLAPELLNLFPG-Q---YPSPSADVFSLGVTLYEVASGLKFPRGATPRMAIP---PLP---------EGRSAE-------LARLIAGCLDFDPAKRATAQEV--------ANFARENV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AALEMGATSM   [530]
'gi|66802342|ref|XP 629953.1| putative protein tyrosine kinase [Dictyostelium discoideum] >gi|60463351|gb|EAL61542.1| putative w'    -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRP----------LP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------DQSAFEDKSELVSKKQKNEDENNENRS------------------------------------------------------------------------------------------------------------------PETPRTPKVCPKT--------------------PTKTPLRT-------------------------------------------------------------------------------------------------------------------------------------------------------PTKNQAGVQFLTQKKRTKSCSSHFEYINQIGEGSFAKVYKARSFVDGRLYAVKKSKKPIWETSER------------------------------NQHIQEIENGMKLG-------------------------------------------HHNNIAQVMCAWEE----GGHIFIQMELCERGNLKDALNLAVQEEGGLGKLPE--YMIWQYLCD---------------------IANGLSHVHEKGIMHLDIKPENLLF----------------SNDG------------------------------------------------VLKIGDFGVCSTTTGG---------------------DDSEGDQIYMAPELLN--DI-H---T--PSADIFSLGITLYEMATNYNLPQKGQWWRNLREG-KIPFPEND----DSISQD-------LKDLIILMMNPDHTKRITIQSL--------LKYDKLQSVITLKRS-----------------TSTLYRLQRKLF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [352]
'gi|24658661|ref|NP 647987.2| Myt1 CG32417-PA [Drosophila melanogaster] >gi|23094124|gb|AAF50747.3| CG32417-PA [Drosophila melan'    ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKHHR----------LP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPELHDDKH---RHKQ-----------------------------------------------------------------------------------------------------------------------------------CNG-ENS--------------------NRFRPPKY--KTR----GYVAVDNNN-LNRS---------------------------------------QSLGSCST-NS---SQIAHA---------ISFRDA---------------------------------------------GCSDSSTLPSSP-VQAELSTLSL---SHFEQCFERLAKLGEGSFGEVFQVRDRSDGQLYAVKISKQLFRGEQYR------------------------------AERLEEVRRYEEFS-------------------------------------------GHENCIRFIRAWEQ----YDRLYMQMELCRE-------SLEQYLLRCQ-RIPE--ERIWHILLD---------------------LLRGLKSLHDRNLIHLDIKLDNVLIG---------------EDDE------------------------------------------------TCKLADFGLVIDVDRA----NSH--------------HATEGDSRYMAPEILQ--GH-F---S--KAADIFSLGIAMLELACYMDLPSNGPLWHELRHG-ILP-EEFI----NKISLE-------LQSVIKSMMKPDPAQRPTAEQL--------LSHPKLQYLQKKRKS-----------------LMNFSMLSRSFRRSRRAVWGRMCNWKTAAFRYLLYFLEVLHLCKPITASQPNI------------------NIVPSSPSSKGVPLVPQVEFQLVGSTPIANRD--------------CYAS----DFLSG------------------EDPLDLSNQGSPNVINSTPLNTNQ---------------------------------------------------------------------------------------------------------------------------GKSRLDLLKNNVDSMGRYVHV-----------HDFESPCSALSSAKVLDTSSFRRKKLFVLEY-DD------E---   [533]
'gi|6942009|gb|AAF32288.1| Myt1 kinase-like protein [Drosophila melanogaster]'                                    ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKHHR----------LP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPELHDDKH---RHKQ-----------------------------------------------------------------------------------------------------------------------------------CNG-ENS--------------------NRFRPPKY--KTR----GYVAVDNNN-LNRS---------------------------------------QSLGSCST-NS---SQIAHA---------ISFRDA---------------------------------------------GCSDSSTLPSSP-VQAELSTLSL---SHFEQCFERLAKLGEGSFGEVFQVRDRSDGQLYAVKISKQLFRGEQYR------------------------------AERLEEVRRYEEFS-------------------------------------------GHENCIRFIRAWEQ----YDRLYMQMELCRE-------SLEQYLLRCQ-RIPE--ERIWHILLD---------------------LLRGLKSLHDRNLIHLDIKLDNVLIG---------------EDDE------------------------------------------------TCKLADFGLVIDVDRA----NSH--------------HATEGDSRYMAPEILQ--GH-F---S--KAADIFSLGIAMLELACYMDLPSNGPLWHELRHG-ILP-EEFI----NKISLE-------LQSVIKSMMKPDPAQRPTAEQL--------LSHPKLQYLQKKRKS-----------------LMNFSMLSRSFRRSRRAVWGRMCNWKTAAFRYLLYFLEVLHLCKPITASQPNI------------------NIVPSSPSSKGVPLVPQVEFQLVGSTPIANRD--------------CYAS----DFLSG------------------EDPLDLSNQGSPNVINSTPLNTNQ---------------------------------------------------------------------------------------------------------------------------GKSRLDLLKNNVDSMGRYVHV-----------HDFESPCSALSSAKVLDTSSFRRKKLSSWNMTTS------E---   [534]
'gi|76652628|ref|XP 600897.2| PREDICTED: similar to protein kinase Myt1 isoform 1 isoform 1 [Bos taurus]'                            -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLMPAEGT-PPPLGGTP----------VP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPAYFRHAEPGFSLKR-----------------------------------------------------------------------------------------------------------------------------------PRGLSRS-------------------LPPRPPAKG--SIP--------------VSRL-----------------------------------------FPPRTPGWH---QPHARR---------VSFR------------------------------------------------DQAS-------EPLQSPGYDPSRPESFFQQSFHRLGRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDR------------------------------TRKLAEVGGHEKVG-------------------------------------------QHPRCVRLEQAWEE----GGILYLQTELCGP-------SLQQHCEAWGASLPE--TQVWGYLRD---------------------TLLALAHLHGQGLVHLDVKPANIFL----------------GPRG------------------------------------------------RCKLGDFGLLVELGAS----GTS--------------EAQEGDPRYMAPELLQ--GS-Y---G--TAADVFSLGLTILEVACNMELPRGGEGWQRLRQG-YLP-PEFT----AGLSSE-------LRSVLVTMLEPDPKLRATAEAL--------LALPVLRQPRPWSVL-----------------WFMAAE-----------ALSRGWALWQALLSLLCW------LWHGLAHPA----------------------SWLQPPGPPATPPGSPPCGLLLDRSLSSTWD----------------------DDSIGPS-------------------------LSPEAVLARAASSTS-----------------------------------------------------------------------------------------------------TP-CSGSPAPRSRHTPRDALDL--------------------------SDIDSEPPRGTFPA------------FEPRNLLSLFEDSL------GPS-   [497]
'gi|55233428|gb|EAL38507.1| ENSANGP00000026444 [Anopheles gambiae str. PEST] >gi|57905218|ref|XP 550868.1| ENSANGP00000026444 [A'    ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MK--SP----------LP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPELFEEDEFSFSFKK-----------------------------------------------------------------------------------------------------------------------------------PRGLHDA-------------------FSRRRPPKL--MQP--------------LNRS------------------------------------------------IN---ASMANV---------ISFR------------------------------------------------LDDS-------RAELSALYNRHKPETYYEQCFEQLTKVGEGSFGEVFKVRSRTDGRLYAVKKSKTYFRSSQCR------------------------------QLCLEEVRRYEQFS-------------------------------------------DHENCVKLYQAWEQ----DDRLYMQMELCRE-------NLEVYAREQQ-QLPD--ERIWSILLD---------------------LLLALKSLHDRNLIHLDIKLDNILV----------------TDDG------------------------------------------------TCKLADFGIVFDLTKS----NPR--------------YATEGDSRYMAPELME--GT-Y---T--KAADIFSLGIATLELACNLELPPNGRMWQRLRNGQPLP-ELLA----RKVSPA-------LKDIIHSMMRPVPTERPTVDVL--------LKHPMLQKLYEARRR------------------------RRIFERTGSYLCRKLSSLARFVLVAVMWLVACFRLQHRKDSPDAKVERGQQKAANKTARSCNGSNLSVGSCSRTGIAFGASRSFQEHCSSLLADDDNEMDFSGTGFDSSACTAAGDDCDRTAGTQDGGGTDKDSVQITPTLNNSMPPTRTPTVRIVNSTPLNHHHHHNDHLHRHHLQFQQTQQSHS--GSRHASRVFCSPLRILWFEDDADDLSILNDSRRNLKASFSNSPTAASSLNDSDNDFRPLGSLSQDLDASGGGKGDGEEAPAPAGKNGTTPAHSSLSSLAVGEQSIT--STPNSSLFKALRTNVSVANGVTASAGCDTPLST-------GHSSFLIKKKLRFNA-ED------EDSD   [686]
'gi|16266769|dbj|BAB69973.1| Myt1 [Asterina pectinifera]'                                    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSDFESSLRENGFRSP----------RP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPK-FLQEQVTFSQKKHR---------------------------------------------------------------------------------------------------------------------------------GTTPRRT-------------------GPPRPPLKS--VPP--------------VSRL-----------------------------------------FPNKTRE-E---ESRPRA---------VSFR------------------------------------------------QSEP-------SVLQSPHYNEKSTESFFNQCFEVVQKLGEGSFGEVYKVKCKEDDKFYAVKRSRERFKGEADR------------------------------KRKLEEVHQHETLS-------------------------------------------RHPNCVEFLKAWAE----KGHLYIQTELCQM-------SLEEYSEGHH-DISE--STVWSFLLD---------------------LMKGVKHLHDHDLLHLDIKPENIFV----------------SMYG------------------------------------------------ACKLGDFGLTVQLGKN----DLT--------------DAQEGDPRYLAPELLQ--GK-F---G--KHADVFSIGITILELACDLDLPQNGQLWHQLRNG-DIP-WDIT----KGISRS-------LKDIITSMMDPDYQRRPSLEDL--------LHLPVMRSVDRRNRV-----------------MLTFRK-----------VWVSILAFLSMLIGILAMFVQI--VTHALRLPVSHM------------------VKSPRRYSKHRDPL----------TGISATPT----------------------TKCFDTDVHGSYGQPLS---NLTFSSDEEKSKVFAEPASYPVISTSG-----------------------------------------------------------------------------------------------------TPLLNRSCRRTPLHQPRSSSPICHGRLNNSFDRWTPNGSPNISAVHDD-------PATPLNLSFDEPKALNKSALEPKNLMQIFEDTD------DN--   [548]
'gi|54640844|gb|EAL29595.1| GA16888-PA [Drosophila pseudoobscura]'                                    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HR----------LP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPELRDDKH---RHKQ-----------------------------------------------------------------------------------------------------------------------------------CNGNENS--------------------NRFRPPKY--KGRLSQGGYVAVENNNGANNS---------------------------------------QSLGSCSAHNS---SNIAHA---------ISFRGV---------------------------------------------EFPDANTLPASPNVQQDASSTDFGDQSHFELCFERLAKLGEGSFGEVFQVRDRSDGRLYAVKISKQLFRGEQYR------------------------------AERLEEVRRYEEFS-------------------------------------------GHENCIRFIRAWEQ----YDRLYMQMELCRE-------SLEQYLLRCQ-QIPE--ERIWHILLD---------------------LLRALKSLHDRNLIHLDIKLDNVLIG---------------EDDE------------------------------------------------TCKLADFGLVIDVDRA----NSQ--------------HATEGDSRYMAPEILQ--GQ-F---S--KAADVFSLGIAMLELACYMELPSNGPLWHELRRG-ILP-EEFI----DKISQE-------LQLVIKSMMMPDPAARPTTDTL--------LSHPKLQRMQENQKS-----------------LITVSNLSRSFRKSRRVVYGKVCNWKSFAYRCLFYLLEILHLYKPISPSQPTI------------------TPAPSSPTT-FLAAVPRVEFQLVGSTPITNRD--------------CYAS----DFLTG------------------DDELELSKQETPHVINSTPLNHNQ---------------------------------------------------------------------------------------------------------------------------GKSRLD--SSRRSSLGKTIPT-----------LELDSPYSNVASLKLFETSSFRRKKLFVLDY-DD------E---   [537]
'gi|55976591|sp|Q9ESG9|PMYT1 MOUSE Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Myt1 kinase) >gi'    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTMPTEGT-PPPLSGTP----------IP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPAYFRHAEPGFSLKR-----------------------------------------------------------------------------------------------------------------------------------PGGLSRS-------------------LPPRPPAKG--CIP--------------VSRL-----------------------------------------FPPRTPGWH---QPQPRR---------VSFL------------------------------------------------CETS-------EPLQSPGYDPSRPESFFQQNFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRYMSPFRGPKDR------------------------------TRKLAEVGGHEKVG-------------------------------------------QHPHCVRLERAWEE----GGILYLQTELCGP-------SLQQHCEAWGASLPE--AQVWGYLRD---------------------ILLALDHLHSQGLVHLDVKPANIFL----------------GPRG------------------------------------------------RCKLGDFGLLVELGST----GAG--------------EAQEGDPRYMAPELLQ--GS-Y---G--TAADVFSLGLTILEVACNMELPHGGEGWQQLRQG-YLP-PEFT----AGLSSE-------LRSVLAMMLEPDPQLRATAEAL--------LALPMLRQPRPWNVL-----------------WYMAAE-----------ALSRGWALWQALVTLLCW------LWHGLVHPA----------------------SWLQPPGPPATPPGSPPCSPLLDSTLSSSWD----------------------NDSIGPS-------------------------LSPETVLSRITRRTS-----------------------------------------------------------------------------------------------------TP-RG-------RYIPRDALDL--------------------------TDVDSEPPRGPCPT------------FEPRNLLSLFEDSL------DPA-   [490]
'gi|9957091|gb|AAG09210.1| MYT1 kinase [Mus musculus] >gi|12746438|ref|NP 075545.1| membrane-associated tyrosine-and threonine-s'    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTMPTEGT-PPPLSGTP----------IP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPAYFRHAEPGFSLKR-----------------------------------------------------------------------------------------------------------------------------------PGGLSRS-------------------LPPRPPAKG--CIP--------------VSRL-----------------------------------------FPPRTPGWH---QPQPRR---------VSFL------------------------------------------------CETS-------EPLQSPGYDPSRPESFFQQNFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRYMSPFRGPKDR------------------------------TRKLAEVGGHEKVG-------------------------------------------QHPHCVRLERAWEE----GGILYLQTELCGP-------SLQQHCEAWGASLPE--AQVWGYLRD---------------------ILLALDHLHSQGLVHLDVKPANIFL----------------GPRG------------------------------------------------RCKLGDFGLLVELGST----GAG--------------EAQEGDPRYMAPELLQ--GS-Y---G--TAADVFSLGLTILEVACNMELPHGGEGWQQLRQG-YLP-PEFT----AGLSSE-------LRSVLAMMLEPDPQLRATAEAL--------LALPMLRQPRPWNVL-----------------WYMAAE-----------ALSRGWALWQALVTLLCW------LWHGLVHPA----------------------SWLQPPGPPATPLGSPPCSPLMNSTLSSSWD----------------------NDSIGPS-------------------------LSPETVLSRITRRTS-----------------------------------------------------------------------------------------------------TP-RG-------RYIPRDALDL--------------------------TDVDSEPPRGPCPT------------FEPRNLLSLFEDSL------DPA-   [490]
'gi|74177270|dbj|BAE34554.1| unnamed protein product [Mus musculus] >gi|74138482|dbj|BAE38056.1| unnamed protein product [Mus mu'    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTMPTEGT-PPPLSGTP----------IP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPAYFRHAEPGFSLKR-----------------------------------------------------------------------------------------------------------------------------------PGGLSRS-------------------LPPRPPAKG--CIP--------------VSRL-----------------------------------------FPPRTPGWH---QPQPRR---------VSFL------------------------------------------------CETS-------EPLQSPGYDPSRPESFFQQNFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRYMSPFRGPKDR------------------------------TRKLAEVGGHEKVG-------------------------------------------QHPHCVRLERAWEE----GGILYLQTELCGP-------SLQQHCEAWGASLPE--AQVWGYLRD---------------------ILLALDHLHSQGLVHLDVKPANIFL----------------GPRG------------------------------------------------RCKLGDFGLLVELGSA----GAG--------------EAQEGDPRYMAPELLQ--GS-Y---G--TAADVFSLGLTILEVACNMELPHGGEGWQQLRQG-YLP-PEFT----AGLSSE-------LRSVLAMMLEPDPQLRATAEAL--------LALPMLRQPRPWNVL-----------------WYMAAE-----------ALSRGWALWQALVTLLCW------LWHGLVHPA----------------------SWLQPPGPPATPPGSPPCSPLLDSTLSSSWD----------------------NDSIGPS-------------------------LSPETVLSRITRRTS-----------------------------------------------------------------------------------------------------TP-RG-------RYIPRDALDL--------------------------TDVDSEPPRGPCPT------------FEPRNLLSLFEDSL------DPA-   [490]
'gi|73959425|ref|XP 547170.2| PREDICTED: similar to protein kinase Myt1 isoform 1 [Canis familiaris]'                                ----------------------------------------------------------------------------------------------------------------------------------------MAGALLRCDEDSEHFVSRWWQMSLQPGPGAKYGKTEEAGLEVPGANPTELAGDSSDSGPPGASPEGSTPCLLMVWPLPSGPLLAPLAKSRGLRLRGEGRGAGSGSGYRSVRIPGTERERRSRQPRPRHAFAGTPHSVAAPARAGAEGTSRLRSDRVRPEEPAATRTQGRGGGAAVLWAPLIGCFGERAGPEAFLGGASRPVWNFWREPVLRAFTGRSPSESPPARRQE----PSAADPRPPDRPSGFRGLC-PPGVGAPAEPRPAHPSSSCFYDLQGTDNSVQAYVYLSPAFSQQVLVPVASMCKAERPPALVMPVPTEGT-PPPLSGTP----------VP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPAYFRHAEPGFSLKR-----------------------------------------------------------------------------------------------------------------------------------PGGLSRS-------------------LPPRPPAKG--SIP--------------ISRL-----------------------------------------FPPRTPGWH---QPQPRR---------VSFR------------------------------------------------GKAS-------ETLQSPSYDPSRPESFFQQSFQRLGRLGHGSYGEVFKVRSKEDGRLYAIKRSMSPFRGPKDR------------------------------ARKLAEVGGHEKVG-------------------------------------------QHPRCVRLEQAWEE----GGILYLQTELCGP-------SLQQHCEAWGTGLPE--AQVWGYLRD---------------------TLLALAHLHGQGLVHLDVKPANIFL----------------GPRG------------------------------------------------RCKLGDFGLLVELGTS----GAG--------------EAQEGDPRYMAPELLQ--GS-Y---G--TAADVFSLGLTVLEVACNMELPHGGEGWQQLRQG-YLP-PEFT----AGLSSE-------LRSVLTMMLEPDPKLRATAEAL--------LALPMLRRPRPWSIL-----------------WYVAAD-----------ALSRGWALWQALLSLLCW------LWHGLAHPA----------------------SWLQPPSPPATPPGSPPCSLLLDSSLSSSWD----------------------DDSIGLS-------------------------LSAEAVLARATGNTS-----------------------------------------------------------------------------------------------------TP-RSGSPAPRNRYTLRDALDL--------------------------SDIDSEPARGSFPS------------FEPRNLLSLFEDSL------GPG-   [805]
'gi|34868732|ref|XP 213222.2| PREDICTED: similar to Membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase ['    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSMPTEGT-PPPLSGTP----------IP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPAYFRHAEPGFSLKR-----------------------------------------------------------------------------------------------------------------------------------PGGLSRS-------------------LPPRPPAKG--SIP--------------VSRL-----------------------------------------FPPRTPGWQ---QPQPRR---------VSFL------------------------------------------------CETS-------ETLQSPGYDPSRPESFFQQNFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDR------------------------------TRKLAEVGGHEKVG-------------------------------------------QHPHCVRLERAWEE----GGILYLQTELCGP-------SLQQHCEAWGASLPE--AQVWGYLRD---------------------TLLALDHLHSQGLVHLDVKPANIFL----------------GPRG------------------------------------------------RCKLGDFGLLVELGSA----GAG--------------EAQEGDPRYMAPELLR--GS-Y---G--TAADVFSLGLTILEVACNMELPHGGEGWQQLRQG-YLP-PEFT----AGLSSE-------LRSVLTMMLEPDPQLRATAEVL--------LALPMLRQPRPWNVL-----------------WYMAAE-----------ALSRGWALWQALVTLLCW------LWHGLVHPA----------------------SWLQPPGPPATPPGSPPCSPLLDSTLSSNWD----------------------DDSIGPS-------------------------LSPETILSRITRRTS-----------------------------------------------------------------------------------------------------TP-RG-------RYTPRDVLDL--------------------------TDMDSEPPRGPCPT------------FEPRNLLSLFEDSL------DPA-   [490]
'gi|34784584|gb|AAH57703.1| Myt1 protein [Xenopus laevis] >gi|55976560|sp|Q91618|PMYT1 XENLA Membrane-associated tyrosine- and t'    -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVPGDDMGETPLTRTP----------IP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPAYFSQAEQSFSLKKR----------------------------------------------------------------------------------------------------------------------------------GRSLCYT-------------------LPPRPPVKS--ALP--------------VSRI-----------------------------------------FPNKQRSWS---QPRPQS---------VSFR------------------------------------------------SPQN-------KTPASKLYDQSKGDTFFKQCFKSICKLGRGSFGEVYKVQSLEDGCFYAVKRSVSPFRGESDR------------------------------QRKLQEVRKHERVG-------------------------------------------EHPNCLRFVRAWEE----KRMLYLQTELCAG-------SLQQHSEEFAGSLPP--RRVWNITCD---------------------LLHGLKHLHDRNLLHLDIKPANVFI----------------SFSG------------------------------------------------VCKLGDFGLMVELDGTE---GSG--------------EAQEGDPRYMAPELLD--GI-F---S--KAADVFSLGMSLLEVACNMELPKGGDGWQQLRQG-HLP-TEFT----SDLPPD-------FLKVLSAMLEPDYRRRATVDWL--------LSLPAIRNAERWRMV-----------------TLAQER-----------TLGKIIAVYQFIVWLLSF------VFQWLNRPVIGF------------------LHYCGLRALPRSPPCSPFPNHLGESSFSSDWD----------------------DESLGDDVFEVPPSPLATHRNLTYHGQELIGRHSPDLLSRPSLGSTS-----------------------------------------------------------------------------------------------------TP-RNLSPEFSMR--KRSALPL----------------TPNVSRISQDSTGKSRSPSTSHSSSGFVDAEVQRTLFLPRNLLGMFDDAT------EQ--   [548]
'gi|33304051|gb|AAQ02533.1| membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [synthetic construct]'       --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M--RPPALAMPMPTEGT-PPPLSGTP----------IP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPAYFRHAEPGFSLKR-----------------------------------------------------------------------------------------------------------------------------------PRGLSRS-------------------LPPPPPAKG--SIP--------------ISRL-----------------------------------------FPPRTPGWH---QLQPRR---------VSFR------------------------------------------------GEAS-------ETLQSPGYDPSRPESFFQQSFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDR------------------------------ARKLAEVGSHEKVG-------------------------------------------QHPCCVRLEQAWEE----GGILYLQTELCGP-------SLQQHCEAWGASLPE--AQVWGYLRD---------------------TLLALAHLHSQGLVHLDVKPANIFL----------------GPRG------------------------------------------------RCKLGDFGLLVELGTA----GAG--------------EVQEGDPRYMAPELLQ--GS-Y---G--TAADVFSLGLTILEVACNMELPHGGEGWQQLRQG-YLP-PEFT----AGLSSE-------LRSVLVMMLEPDPKLRATAEAL--------LALPVLRQPRAWGVL-----------------WCMAAE-----------ALSRGWALWQALLALLCW------LWHGLAHPA----------------------SWLQPLGPPATPPGSPPCSLLLDSSLSSNWD----------------------DDSLGPS-------------------------LSPEAVLARTVGSTS-----------------------------------------------------------------------------------------------------TP-RS-------RCTPRDALDL--------------------------SDINSEPPRGSFPS------------FEPRNLLSLFEDTL------DPTL   [498]
'gi|2914671|gb|AAC04477.1| Myt1 [Homo sapiens]'                                    ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPALAMPMPTEGT-PPPLSGTP----------IP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPAYFRHAEPGFSLKR-----------------------------------------------------------------------------------------------------------------------------------PRGLSRS-------------------LPPPPPAKG--SIP--------------ISRL-----------------------------------------FPPRTPGWH---QLQPRR---------VSFR------------------------------------------------GEAS-------ETLQSPGYDPSRPESFFQQSFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDR------------------------------ARKLAEVGSHEKVG-------------------------------------------QHPCCVRLEQAWEE----GGILYLQTELCGP-------SLQQHCEAWGASLPE--AQVWGYLRD---------------------TLLALAHLHSQGLVHLDVKPANIFL----------------GPRG------------------------------------------------RCKLGDFGLLVELGTA----GAG--------------EVQEGDPRYMAPELLQ--GS-Y---G--TAADVFSLGLTILEVACNMELPHGGEGWQQLRQG-YLP-PEFT----AGLSSE-------LRSVLVMMLEPDPKLRATAEAL--------LALPVLRQPRAWGVL-----------------WCMAAE-----------ALSRGWALWQALLALLCW------LWHGLAHPA----------------------SWLQPLGPPATPPGSPPCSLLLDSSLSSNWD----------------------DDSLGPS-------------------------LSPEAVLARTVGSTS-----------------------------------------------------------------------------------------------------TP-RS-------RCTPRDALDL--------------------------SDINSEPPRGSFPS------------FEPRNLLSLFEDTL------DPT-   [495]
'gi|33383239|ref|NP 872629.1| protein kinase Myt1 isoform 2 [Homo sapiens]'                                    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLERPPALAMPMPTEGT-PPPLSGTP----------IP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPAYFRHAEPGFSLKR-----------------------------------------------------------------------------------------------------------------------------------PRGLSRS-------------------LPPPPPAKG--SIP--------------ISRL-----------------------------------------FPPRTPGWH---QLQPRR---------VSFR------------------------------------------------GEAS-------ETLQSPGYDPSRPESFFQQSFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDR------------------------------ARKLAEVGSHEKVG-------------------------------------------QHPCCVRLEQAWEE----GGILYLQTELCGP-------SLQQHCEAWGASLPE--AQVWGYLRD---------------------TLLALAHLHSQGLVHLDVKPANIFL----------------GPRG------------------------------------------------RCKLGDFGLLVELGTA----GAG--------------EVQEGDPRYMAPELLQ--GS-Y---G--TAADVFSLGLTILEVACNMELPHGGEGWQQLRQG-YLP-PEFT----AGLSSE-------LRSVLVMMLEPDPKLRATAEAL--------LALPVLRQPRAWGVL-----------------WCMAAE-----------ALSRGWALWQALLALLCW------LWHGLAHPA----------------------SWLQPLGPPATPPGSPPCSLLLDSSLSSNWD----------------------DDSLGPG-------------------------HPP--CLACPPAGLH-----------------------------------------------------------------------------------------------------SP-LR-------LSWP----GL--------------------------WGAPPPPGAGAHPG------------M--------------------PWT   [480]
'gi|2460023|gb|AAB71843.1| membrane-associated kinase [Homo sapiens]'                                    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLERPPALAMPMPTEGT-PPPLSGTP----------IP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPAYFRHAEPGFSLKR-----------------------------------------------------------------------------------------------------------------------------------PRGLSRS-------------------LPPPPPAKG--SIP--------------ISRL-----------------------------------------FPPRTPGWH---QLQPRR---------VSFR------------------------------------------------GEAS-------ETLQSPGYDPSRPESFFQQSFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDR------------------------------ARKLAEVGSHEKVG-------------------------------------------QHPCCVRLEQAWEE----GGILYLQTELCGP-------SLQQHCEAWGASLPE--AQVWGYLRD---------------------TLLALAHLHSQGLVHLDVKPANIFL----------------GPRG------------------------------------------------RCKLGDFGLLVELGTA----GAG--------------EVQEGDPRYMAPELLQ--GS-Y---G--TAADVFSLGLTILEVACNMELPHGGEGWQQLRQG-YLP-PEFT----AGLSSE-------LRSVLVMMLEPDPKLRATAEAL--------LALPVLRQPRAWGVL-----------------WCMAAE-----------ALSRGWALWQALLALLCW------LWHGLAHPA----------------------SWLQPLGPPATPPDSPPCSLLLDSSFSSNWD----------------------DDSLGPS-------------------------LSPEAVLARTVGSTS-----------------------------------------------------------------------------------------------------TP-RS-------RCTPRDALDL--------------------------SDINSEPPRGSFPS------------FEPRNLLSMFEDTL------DPT-   [499]
'gi|33383241|ref|NP 004194.3| protein kinase Myt1 isoform 1 [Homo sapiens] >gi|23955950|gb|AAN40703.1| membrane-associated tyros'    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLERPPALAMPMPTEGT-PPPLSGTP----------IP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPAYFRHAEPGFSLKR-----------------------------------------------------------------------------------------------------------------------------------PRGLSRS-------------------LPPPPPAKG--SIP--------------ISRL-----------------------------------------FPPRTPGWH---QLQPRR---------VSFR------------------------------------------------GEAS-------ETLQSPGYDPSRPESFFQQSFQRLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDR------------------------------ARKLAEVGSHEKVG-------------------------------------------QHPCCVRLEQAWEE----GGILYLQTELCGP-------SLQQHCEAWGASLPE--AQVWGYLRD---------------------TLLALAHLHSQGLVHLDVKPANIFL----------------GPRG------------------------------------------------RCKLGDFGLLVELGTA----GAG--------------EVQEGDPRYMAPELLQ--GS-Y---G--TAADVFSLGLTILEVACNMELPHGGEGWQQLRQG-YLP-PEFT----AGLSSE-------LRSVLVMMLEPDPKLRATAEAL--------LALPVLRQPRAWGVL-----------------WCMAAE-----------ALSRGWALWQALLALLCW------LWHGLAHPA----------------------SWLQPLGPPATPPGSPPCSLLLDSSLSSNWD----------------------DDSLGPS-------------------------LSPEAVLARTVGSTS-----------------------------------------------------------------------------------------------------TP-RS-------RCTPRDALDL--------------------------SDINSEPPRGSFPS------------FEPRNLLSLFEDTL------DPT-   [499]
'gi|68435455|ref|XP 700027.1| PREDICTED: similar to membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase ['    -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTSHQ-TPVVSSTP----------LP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPTHFSNAQHSITVKKRKPPFSNLSDS------------------------------------------------------------------------------------------------------------------SQSPSPP--LYHS-------------------LPPRPPSKG--CSP--------------VSRV-----------------------------------------FPHRSIQWT---PL--------------SRS------------------------------------------------LIES-------PPPLSV-YDPSQQQSFFSQCFTNLGLIGRGSFGEVFKVVSLTDNCQYAVKRSVHRFRSEVER------------------------------AKSITEAWNHEELH-------------------------------------------PHPYILGFIAAWEE----AGHLYIQTELCCT-------SLLLYAEETPCHTGE--MRAWAYLCD---------------------MLSALIHLHDCGFAHLDIKPANFFI----------------TKSG------------------------------------------------RLKLGDFGLLIKLPAN----AQKQVNEEKREMKKERDDLQEGDPRYMAPELLR--GD-Y---G--TAADIFSLGISILELACNIEVPKEGDDWQLLRNG-HLP-EEFT----NVLSEE-------MLYILRLMLTPEPCYRASAQQL--------LSLPFVRKHKWKRHL-----------------YLCIIE---------------------SFLTLFQW---S--QWDDDDAPY----------------------PTLQMVESPLQSVGE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   [419]
;
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